Disease Models, Animal Concept

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•   Journal Articles
• 2 Mechanisms of action of low molecular weight heparins and heparinoids  Journal Articles
• 4-Phenylbutyric acid mitigates ER stress-induced neurodegeneration in the spinal cords of a GM2 gangliosidosis mouse model.  Journal Articles
• 4-phenylbutyrate and valproate treatment attenuates the progression of atherosclerosis and stabilizes existing plaques  Journal Articles
• 4D intravital imaging identifies platelets as the predominant cellular procoagulant surface in a mouse hemostasis model  Journal Articles
• 5-HT2A/C receptors do not mediate the attenuation of compulsive checking by mCPP in the quinpirole sensitization rat model of obsessive–compulsive disorder (OCD)  Journal Articles
• Chlamydia pneumoniaeInfection of Endothelial Cells Induces Transcriptional Activation of Platelet‐Derived Growth Factor–B: A Potential Link to Intimal Thickening in a Rabbit Model of Atherosclerosis  Journal Articles
• Lactobacillus reuteri–induced Regulatory T cells Protect against an Allergic Airway Response in Mice  Journal Articles
• N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor  Journal Articles
• Respirology year‐in‐review 2008: Basic science  Journal Articles
• Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis  Journal Articles
• RNA‐sequencing profiles hippocampal gene expression in a validated model of cancer‐induced depression  Journal Articles
• ¹H NMR-based metabolite profiling of diet-induced obesity in a mouse mode  Journal Articles
• A Broad-Spectrum Infection Diagnostic that Detects Pathogen-Associated Molecular Patterns (PAMPs) in Whole Blood  Journal Articles
• A Chronic Inflammatory Infusion Model of Peritoneal Dialysis in Rats  Journal Articles
• A Clinical Diagnostic Test for Calcium Release Deficiency Syndrome  Journal Articles
• A Complex Dietary Supplement Extends Longevity of Mice  Journal Articles
• A Highly Effective Component Vaccine against Nontyphoidal Salmonella enterica Infections  Journal Articles
• A Mouse Model of Airway Disease: Oncostatin M-Induced Pulmonary Eosinophilia, Goblet Cell Hyperplasia, and Airway Hyperresponsiveness Are STAT6 Dependent, and Interstitial Pulmonary Fibrosis Is STAT6 Independent  Journal Articles
• A Novel Mouse Model of Enteric Vibrio parahaemolyticus Infection Reveals that the Type III Secretion System 2 Effector VopC Plays a Key Role in Tissue Invasion and Gastroenteritis  Journal Articles
• A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada  Journal Articles
• A Study of the Purine Derivative AIT-082 in G93A SOD1 Transgenic Mice  Journal Articles
• A Surgical Device to Study the Efficacy of Bioengineered Skin Substitutes in Mice Wound Healing Models  Journal Articles
• A bioabsorbable (polyglactin), nonrestrictive, external sheath inhibits porcine saphenous vein graft thickening  Journal Articles
• A critical role for IL‐15 in TLR‐mediated innate antiviral immunity against genital HSV‐2 infection  Journal Articles
• A ligand of the p65/p95 receptor suppresses perforant path kindling, kindling-induced mossy fiber sprouting, and hilar area changes in adult rats  Journal Articles
• A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium  Journal Articles
• A marine microbiome antifungal targets urgent-threat drug-resistant fungi  Journal Articles
• A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis  Journal Articles
• A non-anticoagulant synthetic pentasaccharide reduces inflammation in a murine model of kidney ischemia-reperfusion injury  Journal Articles
• A non-inflammatory form of immune competence prevails in acute pre-pubescent malnutrition: new evidence based on critical mRNA transcripts in the mouse  Journal Articles
• A non-surgical model of cervical spinal cord injury induced with focused ultrasound and microbubbles  Journal Articles
• A novel copy number variant in the murine Cdh23 gene gives rise to profound deafness and vestibular dysfunction  Journal Articles
• A novel experimental approach in treating central nervous system lupus: Kudos and Kicks  Journal Articles
• A novel microbe-based treatment that attenuates the inflammatory profile in a mouse model of allergic airway disease  Journal Articles
• A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease  Journal Articles
• A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models  Journal Articles
• A point mutation in the neu1 promoter recruits an ectopic repressor, Nkx3.2 and results in a mouse model of sialidase deficiency  Journal Articles
• A polymicrobial view of disease potential in Crohn's-associated adherent-invasive E. coli  Journal Articles
• A porcine model of full-thickness burn, excision and skin autografting  Journal Articles
• A proposed mechanism for intermediate atresia ani (AA), based on a porcine case of AA and hypospadias  Journal Articles
• A role for CD4⁺ T cells in the pathogenesis of skin fibrosis in tight skin mice  Journal Articles
• A role for sensory nerves in the late asthmatic response  Journal Articles
• A short term high-fat high-sucrose diet in mice impairs optic nerve recovery after injury and this is not reversed by exercise  Journal Articles
• A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis  Journal Articles
• A virtual library for behavioral performance in standard conditions—rodent spontaneous activity in an open field during repeated testing and after treatment with drugs or brain lesions  Journal Articles
• AAV-mediated expression of 3TSR inhibits tumor and metastatic lesion development and extends survival in a murine model of epithelial ovarian carcinoma  Journal Articles
• ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer  Journal Articles
• ABT-898 Induces Tumor Regression and Prolongs Survival in a Mouse Model of Epithelial Ovarian Cancer  Journal Articles
• AHNAK Loss in Mice Promotes Type II Pneumocyte Hyperplasia and Lung Tumor Development  Journal Articles
• AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism  Journal Articles
• ANTI-INTERLEUKIN-12 THERAPY PROTECTS MICE IN LETHAL ENDOTOXEMIA BUT IMPAIRS BACTERIAL CLEARANCE IN MURINE ESCHERICHIA COLI PERITONEAL SEPSIS  Journal Articles
• AP-2α knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis  Journal Articles
• Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice  Journal Articles
• Abnormal Social Interactions in a Drosophila Mutant of an Autism Candidate Gene: Neuroligin 3  Journal Articles
• Abnormal megakaryocyte development and platelet function in Nbeal2−/− mice  Journal Articles
• Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy  Journal Articles
• Accelerated Mammary Tumor Onset in a HER2/ Neu Mouse Model Exposed to DDT Metabolites Locally Delivered to the Mammary Gland  Journal Articles
• Actinomyces viscosus promotes neuroprotection in C. elegans models of Parkinson's disease.  Journal Articles
• Activated protein C improves intestinal microcirculation in experimental endotoxaemia in the rat.  Journal Articles
• Active modification of host inflammation bySalmonella  Journal Articles
• Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease  Journal Articles
• Activin mRNA induced during amygdala kindling shows a spatiotemporal progression that tracks the spread of seizures  Journal Articles
• Acute Infectious Gastroenteritis Potentiates a Crohn's Disease Pathobiont to Fuel Ongoing Inflammation in the Post-Infectious Period  Journal Articles
• Acute anosmia in the rat: A behavioral test of a peripherally-induced olfactory deficit  Journal Articles
• Acute harmine administration induces antidepressive-like effects and increases BDNF levels in the rat hippocampus  Journal Articles
• Acute low dose of MK-801 prevents memory deficits without altering hippocampal DARPP-32 expression and BDNF levels in sepsis survivor rats  Journal Articles
• Acute propranolol infusion stimulates protein synthesis in rabbit skin wound  Journal Articles
• Acute, next‐generation AMPK activation initiates a disease‐resistant gene expression program in dystrophic skeletal muscle  Journal Articles
• Adaptation following intestinal resection: mechanisms and signals  Journal Articles
• Addition of an Fc-IgG induces receptor clustering and increases the in vitro efficacy and in vivo anti-tumor properties of the thrombospondin-1 type I repeats (3TSR) in a mouse model of advanced stage ovarian cancer  Journal Articles
• Adenoviral Gene Transfer of Interleukin-1 in Combination with Oncostatin M Induces Significant Joint Damage in a Murine Model  Journal Articles
• Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract.  Journal Articles
• Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans  Journal Articles
• Adipose browning response to burn trauma is impaired with aging  Journal Articles
• Adjuvant and Anti-Inflammatory Properties of Cigarette Smoke in Murine Allergic Airway Inflammation  Journal Articles
• Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination  Journal Articles
• Administration of dexamethasone protects mice against ischemia/reperfusion induced renal injury by suppressing PI3K/AKT signaling.  Journal Articles
• Administration of systemic matrix metalloproteinase inhibitors maintains bone mechanical integrity in adjuvant arthritis.  Journal Articles
• Adoptive transfer of macrophage from mice with depression-like behavior enhances susceptibility to colitis  Journal Articles
• Adult skin-derived precursor Schwann cells exhibit superior myelination and regeneration supportive properties compared to chronically denervated nerve-derived Schwann cells  Journal Articles
• Advances in Humanized Mouse Models to Improve Understanding of HIV-1 Pathogenesis and Immune Responses  Journal Articles
• Advances in the pathology of COPD  Journal Articles
• Adverse Fetal and Neonatal Outcomes Associated with a Life-Long High Fat Diet: Role of Altered Development of the Placental Vasculature  Journal Articles
• Adverse metabolic effects of a hypercaloric, high-fat diet in rodents precede observable changes in body weight  Journal Articles
• Age at Mycobacterium bovis BCG Priming Has Limited Impact on Anti-Tuberculosis Immunity Boosted by Respiratory Mucosal AdHu5Ag85A Immunization in a Murine Model  Journal Articles
• Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression.  Journal Articles
• Air Pollution—Who “Nose” What Chronic Exposure Models Will Reveal Next?  Journal Articles
• Airway Macrophages Mediate Mucosal Vaccine–Induced Trained Innate Immunity against Mycobacterium tuberculosis in Early Stages of Infection  Journal Articles
• Airway smooth muscle in asthma: Phenotype plasticity and function  Conferences
• Akt isoform specific effects in ovarian cancer progression  Journal Articles
• Allergen-Induced Increase in Airway Responsiveness, Airway Eosinophilia, and Bone-Marrow Eosinophil Progenitors in Mice  Journal Articles
• Allergen-induced changes in bone marrow progenitors and airway responsiveness in dogs and the effect of inhaled budesonide on these parameters.  Journal Articles
• Allergic inflammation triggers dyslipidemia via IgG signalling  Journal Articles
• Alpha‐1 Acid Glycoprotein Reduces Hepatic Leukocyte Recruitment in Murine Models of Either Early Endotoxemia or Early Sepsis  Journal Articles
• Alteration of perivascular adipose tissue function in angiotensin II-induced hypertension  Journal Articles
• Altered colonic function and microbiota profile in a mouse model of chronic depression  Journal Articles
• Altered olfactory function in the MRL model of CNS lupus  Journal Articles
• Altered physiology of acid secretion in depression‐prone Flinders rats results in exacerbated NSAID and stress‐induced gastric damage  Journal Articles
• Altered sphingolipid profile in response to skeletal muscle injury in a mouse model of type 1 diabetes mellitus.  Journal Articles
• Amelioration of ovalbumin-induced allergic airway disease following Der p 1 peptide immunotherapy is not associated with induction of IL-35  Journal Articles
• An Official ATS Conference Proceedings: Advances in Small-Animal Imaging Application to Lung Pathophysiology  Journal Articles
• An Official American Thoracic Society Research Statement: Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling  Journal Articles
• An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis  Journal Articles
• An Overview of Some Reproductive Toxicology Studies Conducted At Health Canada  Conferences
• An approach to feeding high-percentage fish diets to mice for human and wildlife toxicology studies  Journal Articles
• An aptamer‐based magnetic resonance imaging contrast agent for detecting oligomeric amyloid‐β in the brain of an Alzheimer's disease mouse model  Journal Articles
• An autoantibody identifies arrhythmogenic right ventricular cardiomyopathy and participates in its pathogenesis  Journal Articles
• An effective kinase inhibition strategy for metastatic recurrent childhood medulloblastoma  Journal Articles
• An important role for the activation peptide domain in controlling factor IX levels in the blood of haemophilia B mice  Conferences
• An in vivo model of anti-inflammatory activity of subdural dexamethasone following the spinal cord injury  Journal Articles
• An investigation of the mechanism of adjacent segment disease in a porcine spine model.  Journal Articles
• An orally active non-selective endothelin receptor antagonist, bosentan, markedly reduces injury in a rat model of colitis  Journal Articles
• An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line  Journal Articles
• Analysis of the Contribution of Salmonella Pathogenicity Islands 1 and 2 to Enteric Disease Progression Using a Novel Bovine Ileal Loop Model and a Murine Model of Infectious Enterocolitis  Journal Articles
• Anatomical location of injected microglia in different activation states and time course of injury determines survival of retinal ganglion cells after optic nerve crush.  Journal Articles
• Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression  Journal Articles
• Animal Models for Nervous System Disease in Systemic Lupus Erythematosus  Journal Articles
• Animal Models of Chronic Obstructive Pulmonary Disease Exacerbations  Journal Articles
• Animal Models of Thrombosis From Zebrafish to Nonhuman Primates  Journal Articles
• Animal models of COPD: What do they tell us?  Journal Articles
• Animal models of airway inflammation and airway smooth muscle remodelling in asthma  Conferences
• Animal models of pulmonary fibrosis: how far from effective reality?  Journal Articles
• Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy  Journal Articles
• Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions  Journal Articles
• Anti-Inflammatory Effects of Tanshinone IIA on Atherosclerostic Vessels of Ovariectomized ApoE-/- Mice are Mediated by Estrogen Receptor Activation and Through the ERK Signaling Pathway  Journal Articles
• Anticoagulant-Related Nephropathy  Journal Articles
• Antidepressants Attenuate Increased Susceptibility to Colitis in a Murine Model of Depression  Journal Articles
• Antifibrotic Effects of a Recombinant Adeno-Associated Virus Carrying Small Interfering RNA Targeting TIMP-1 in Rat Liver Fibrosis  Journal Articles
• Antifibrotic Role of αB-Crystallin Inhibition in Pleural and Subpleural Fibrosis  Journal Articles
• Antimicrobial Efficacy of a New Chlorhexidine-based Device Against Staphylococcus aureus Colonization of Venous Catheters  Journal Articles
• Antithrombotic Activity of the Novel Oral Anticoagulant, Tecarfarin [Sodium 3-[4-((1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yloxy) carbonyl) benzyl]-2-oxo-2H-chromen-4-olate] in Animal Models  Journal Articles
• Antithrombotic Properties of Heparin in a Neonatal Piglet Model of Thrombin-Induced Thrombosis  Journal Articles
• Anti‐ulcerogenic properties of endothelin receptor antagonists in the rat  Journal Articles
• Aortic endothelial cell von Willebrand factor content, and circulating plasminogen activator inhibitor-1 are increased, but expression of endothelial leukocyte adhesion molecules is unchanged in insulin-dependent diabetic BB rats  Journal Articles
• Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein.  Journal Articles
• Apoptotic Cell Death in Mouse Models of GM2 Gangliosidosis and Observations on Human Tay-Sachs and Sandhoff Diseases  Journal Articles
• Assessment of Influenza Virus Hemagglutinin Stalk-Based Immunity in Ferrets  Journal Articles
• Assessment of myocardial fibrosis by endoventricular electromechanical mapping in experimental nonischemic cardiomyopathy  Journal Articles
• Assessment of virulence diversity of methicillin-resistant Staphylococcus aureus strains with a Drosophila melanogaster infection model  Journal Articles
• Associations between parenting behavior and anxiety in a rodent model and a clinical sample: relationship to peripheral BDNF levels  Journal Articles
• Astrocyte-mediated disruption of ROS homeostasis in Fragile X mouse model  Journal Articles
• Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model  Journal Articles
• Astrocytes Prevent Abnormal Neuronal Development in the Fragile X Mouse  Journal Articles
• Astrocyte‐mediated purinergic signaling is upregulated in a mouse model of Fragile X syndrome  Journal Articles
• Attenuating immune pathology using a microbial-based intervention in a mouse model of cigarette smoke-induced lung inflammation  Journal Articles
• Attenuation of Age-Related Muscle Wasting and Weakness in Rats After Formoterol Treatment: Therapeutic Implications for Sarcopenia  Journal Articles
• Attenuation of mania-like behavior in Na+,K+-ATPase α3 mutant mice by prospective therapies for bipolar disorder: Melatonin and exercise  Journal Articles
• Autoimmune Manifestations in the 3xTg-AD Model of Alzheimer's Disease  Journal Articles
• Autoimmune-induced damage of the midbrain dopaminergic system in lupus-prone mice  Journal Articles
• Autologous, lentivirus‐modified, T‐rapa cell “micropharmacies” for lysosomal storage disorders  Journal Articles
• AxGxE: Using Flies to Interrogate the Complex Etiology of Neurodegenerative Disease.  Chapters
• B7RP-1 Is Not Required for the Generation of Th2 Responses in a Model of Allergic Airway Inflammation but Is Essential for the Induction of Inhalation Tolerance  Journal Articles
• BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog  Journal Articles
• BF061, a novel antiplatelet and antithrombotic agent targeting P2Y12 receptor and phosphodiesterase  Journal Articles
• BL-7010 Demonstrates Specific Binding to Gliadin and Reduces Gluten-Associated Pathology in a Chronic Mouse Model of Gliadin Sensitivity  Journal Articles
• BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis  Journal Articles
• Bacterial Genetic Determinants of Non‐O157 STEC Outbreaks and Hemolytic‐Uremic Syndrome after Infection  Journal Articles
• Basic and Translational Research in Intracerebral Hemorrhage  Journal Articles
• Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)  Journal Articles
• Behavioral abnormalities in synapsin II knockout mice implicate a causal factor in schizophrenia  Journal Articles
• Behavioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid  Journal Articles
• Behavioral and neurochemical effects of sodium butyrate in an animal model of mania  Journal Articles
• Behavioral consequences of bone marrow transplantation in the treatment of murine mucopolysaccharidosis type VII.  Journal Articles
• Behavioral effects of infection with interferon-gamma adenovector  Journal Articles
• Behavioral heterogeneity in an animal model of neuropsychiatric lupus  Journal Articles
• Behavioral impairment in the monkey following implantation of aluminum hydroxide on the temporal cortex: The role of cortical destruction  Journal Articles
• Behavioural abnormalities in a murine model of a human lysosomal storage disease  Journal Articles
• Beneficial effect of ginseng root in SOD-1 (G93A) transgenic mice  Journal Articles
• Bi-phasic gliosis drives neuropathology in a Sandhoff disease mouse model  Journal Articles
• Bilateral upregulation of α-synuclein expression in the mouse substantia nigra by intracranial rotenone treatment  Journal Articles
• Bilirubin Decreases Macrophage Cholesterol Efflux and ATP-Binding Cassette Transporter A1 Protein Expression.  Journal Articles
• Binge-eating disorder: Clinical and therapeutic advances  Journal Articles
• Binocular visual training to promote recovery from monocular deprivation  Journal Articles
• Bioluminescence Tomography–Guided Radiation Therapy for Preclinical Research  Journal Articles
• Biomarkers of inflammation and repair in kidney disease progression  Journal Articles
• Blast-Induced Tinnitus and Hearing Loss in Rats: Behavioral and Imaging Assays  Journal Articles
• Bone Affinity of a Bisphosphonate-Conjugated Protein in Vivo  Journal Articles
• Bone Formation Following Intramedullary Femoral Reaming Is Decreased by Indomethacin and Antibodies to Insulin-like Growth Factors  Journal Articles
• Bone cancer-induced pain is associated with glutamate signalling in peripheral sensory neurons  Journal Articles
• Bone marrow contribution to eosinophilic inflammation  Conferences
• Bortezomib protects from varicose‐like venous remodeling  Journal Articles
• Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection  Journal Articles
• Both sexes develop DKD in the CD1 uninephrectomized streptozotocin mouse model  Journal Articles
• Brain creatine kinase activity in an animal model of mania  Journal Articles
• Budesonide prevents but does not reverse sustained airway hyperresponsiveness in mice  Journal Articles
• CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection  Journal Articles
• CD206⁺macrophages are relevant non-invasive imaging biomarkers and therapeutic targets in experimental lung fibrosis  Journal Articles
• CD4+ T-Cell Modulation of Visceral Nociception in Mice  Journal Articles
• CORM-3-derived CO modulates polymorphonuclear leukocyte migration across the vascular endothelium by reducing levels of cell surface-bound elastase  Journal Articles
• Caloric Restriction Shortens Lifespan through an Increase in Lipid Peroxidation, Inflammation and Apoptosis in the G93A Mouse, an Animal Model of ALS  Journal Articles
• Can an Antibiotic (Macrolide) Prevent Chlamydia pneumoniae -Induced Atherosclerosis in a Rabbit Model?  Journal Articles
• Cancer immunology and canine malignant melanoma: A comparative review  Journal Articles
• Canine models for human genetic neurodegenerative diseases  Journal Articles
• Cell therapy in the treatment of bipolar mania in an animal model: a proof of concept study  Journal Articles
• Cellular and physiological roles of SR-BI, a lipoprotein receptor which mediates selective lipid uptake  Journal Articles
• Cellular magnetic resonance imaging of monocyte-derived dendritic cell migration from healthy donors and cancer patients as assessed in a scid mouse model  Journal Articles
• Cerebrolysin modulates pronerve growth factor/nerve growth factor ratio and ameliorates the cholinergic deficit in a transgenic model of Alzheimer's disease  Journal Articles
• Changes in Aβ Non-Nociceptive Primary Sensory Neurons in a Rat Model of Osteoarthritis Pain  Journal Articles
• Changes in cross‐sectional geometry of the distal femoral metaphysis associated with inflammatory arthritis are reduced by a bisphosphonate (zoledronate)  Journal Articles
• Changes in gut microbiota during development of compulsive checking and locomotor sensitization induced by chronic treatment with the dopamine agonist quinpirole  Journal Articles
• Changes in parvalbumin immunoreactive retinal ganglion cells and amacrine cells after optic nerve injury  Journal Articles
• Characterization of Inflammatory Responses During Intranasal Colonization with <em>Streptococcus pneumoniae</em>  Journal Articles
• Characterization of Proliferating Lesion‐Resident Cells During All Stages of Atherosclerotic Growth  Journal Articles
• Characterization of Retinal Microvascular Complications and the Effects of Endoplasmic Reticulum Stress in Mouse Models of Diabetic Atherosclerosis  Journal Articles
• Characterization of ileal dendritic cell distribution in a rat model of acute and chronic inflammation  Journal Articles
• Characterization of the optic nerve and retinal ganglion cell layer in the dysmyelinated adult Long Evans Shaker rat: Evidence for axonal sprouting  Journal Articles
• Characterization of the stress-inducing effects of homocysteine  Journal Articles
• Characterizing the Role of Glycogen Synthase Kinase-3α/β in Macrophage Polarization and the Regulation of Pro-Atherogenic Pathways in Cultured Ldlr-/- Macrophages  Journal Articles
• Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology  Journal Articles
• Cholinergic neurodegeneration in Alzheimer disease mouse models  Chapters
• Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice  Journal Articles
• Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle  Journal Articles
• Chronic Lead Exposure Effects in the Cynomolgus Monkey (Macaca fascicularis) Testis  Journal Articles
• Chronic Mild Stress Paradigm Reduces Sweet Food Intake in Rats without Affecting Brain Derived Neurotrophic Factor Protein Levels  Journal Articles
• Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus  Journal Articles
• Chronic exercise mitigates disease mechanisms and improves muscle function in myotonic dystrophy type 1 mice  Journal Articles
• Chronic low-dose melatonin treatment maintains nigrostriatal integrity in an intrastriatal rotenone model of Parkinson’s disease  Journal Articles
• Chronic peripheral administration of corticotropin-releasing factor causes colonic barrier dysfunction similar to psychological stress  Journal Articles
• Chronically Elevating Circulating Ketones Can Reduce Cardiac Inflammation and Blunt the Development of Heart Failure  Journal Articles
• Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice  Journal Articles
• Cigarette Smoke Differentially Affects Eosinophilia and Remodeling in a Model of House Dust Mite Asthma  Journal Articles
• Cigarette smoke upregulates pulmonary vascular matrix metalloproteinases via TNF-α signaling  Journal Articles
• Cigarette smoke-induced inflammation and respiratory host defense: Insights from animal models  Conferences
• Cigarette smoke-initiated autoimmunity facilitates sensitisation to elastin-induced COPD-like pathologies in mice  Journal Articles
• Circulating Peroxiredoxin-1 is a novel damage-associated molecular pattern and aggravates acute liver injury via promoting inflammation  Journal Articles
• Circulating brain-reactive autoantibodies and behavioral deficits in the MRL model of CNS lupus  Journal Articles
• Classification of Multiple Seizure-Like States in Three Different Rodent Models of Epileptogenesis  Journal Articles
• Classification of Visual Cortex Plasticity Phenotypes following Treatment for Amblyopia  Journal Articles
• Clinical Use of Creatine in Neuromuscular and Neurometabolic Disorders  Journal Articles
• Clinical and pathological findings in dogs following supralethal total body irradiation with and without infusion of autologous long-term marrow culture cells.  Journal Articles
• Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity  Journal Articles
• Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models  Journal Articles
• Co-factors, Microbes, and Immunogenetics in Celiac Disease to Guide Novel Approaches for Diagnosis and Treatment  Journal Articles
• Cobalt Cardiomyopathy  Journal Articles
• Colchicine attenuates renal injury in a model of hypertensive chronic kidney disease  Journal Articles
• Colchicine pre-treatment and post-treatment does not worsen bleeding or functional outcome after collagenase-induced intracerebral hemorrhage  Journal Articles
• Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation  Journal Articles
• Colonization-Resistant Antimicrobial-Coated Peritoneal Dialysis Catheters: Evaluation in a Newly Developed Rat Model of Persistent Pseudomonas Aeruginosa Peritonitis  Journal Articles
• Combined administration of barbourin–albumin and hirudin–albumin fusion proteins limits fibrin(ogen) deposition on the rabbit balloon-injured aorta  Journal Articles
• Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial–lysosomal axis and alleviates autophagic blockage in Pompe disease  Journal Articles
• Combining Vascular Normalization with an Oncolytic Virus Enhances Immunotherapy in a Preclinical Model of Advanced-Stage Ovarian Cancer  Journal Articles
• Comments on Point:Counterpoint: Estrogen and sex do/do not influence post-exercise indexes of muscle damage, inflammation, and repair  Journal Articles
• Communicating hydrocephalus in adult rats with kaolin obstruction of the basal cisterns or the cortical subarachnoid space  Journal Articles
• Comparative Hemodynamic Effects of Contemporary Percutaneous Mechanical Circulatory Support Devices in a Porcine Model of Acute Myocardial Infarction  Journal Articles
• Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus  Journal Articles
• Comparing Current and Next-Generation Humanized Mouse Models for Advancing HIV and HIV/Mtb Co-Infection Studies  Journal Articles
• Comparison between conventional and "clinical" assessment of experimental lung fibrosis  Journal Articles
• Comparison of Aerosol and Intranasal Challenge in a Mouse Model of Allergic Airway Inflammation and Hyperresponsiveness  Journal Articles
• Comparison of the effect of coagulation and platelet function impairments on various mouse bleeding models  Journal Articles
• Comparison of the effect of dabigatran and dalteparin on thrombus stability in a murine model of venous thromboembolism  Journal Articles
• Complete mitochondrial genome sequence of the heart failure model of cardiomyopathic Syrian hamster ( Mesocricetus auratus )  Journal Articles
• Comprehensive Plasma Metabolomic Analyses of Atherosclerotic Progression Reveal Alterations in Glycerophospholipid and Sphingolipid Metabolism in Apolipoprotein E-deficient Mice  Journal Articles
• Comprehensive metabolomics identifies the alarmin uric acid as a critical signal for the induction of peanut allergy  Journal Articles
• Compulsive checking behavior of quinpirole-sensitized rats as an animal model of Obsessive-Compulsive Disorder(OCD): form and control.  Journal Articles
• Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions  Journal Articles
• Context gives meaning. Commentary on Badiani and Robinson Drug-induced neurobehavioral plasticity: the role of environmental context  Journal Articles
• Continuous Exposure to 2,3,7,8-Tetrachlorodibenzo-P-Dioxin Inhibits the Growth of Surgically Induced Endometriosis in the Ovariectomized Mouse Treated with high Dose Estradiol  Journal Articles
• Continuous Exposure to House Dust Mite Elicits Chronic Airway Inflammation and Structural Remodeling  Journal Articles
• Contrast‐enhanced magnetic resonance angiography of carotid arterial wall in pigs  Journal Articles
• Contributions of electron microscopy to the study of myocardial ischaemia.  Journal Articles
• Control of Motoneuron Survival by Angiogenin  Journal Articles
• Converging purinergic and immune signaling pathways drive IL-6 secretion by Fragile X cortical astrocytes via STAT3  Journal Articles
• Correlative single photon emission computed tomography imaging of [123I]altropane binding in the rat model of Parkinson's  Journal Articles
• Cortical Bone Blood Flow in Loose and Tight Fitting Locked Unreamed Intramedullary Nailing  Journal Articles
• Counterpoint to: The Utility of the Rodent Synergist Ablation Model in Identifying Molecular and Cellular Mechanisms of Skeletal Muscle Hypertrophy  Journal Articles
• Creatine supplementation and riluzole treatment provide similar beneficial effects in copper, zinc superoxide dismutase (G93A) transgenic mice  Journal Articles
• Critical Periods in Vision Revisited  Journal Articles
• Critical windows of exposure for children's health: the reproductive system in animals and humans.  Journal Articles
• Crocetin Prevents Dexamethasone-Induced Insulin Resistance in Rats  Journal Articles
• Crocetin improves the insulin resistance induced by high‐fat diet in rats  Journal Articles
• Crosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis  Journal Articles
• Current Concepts in Mechanisms of Emphysema  Journal Articles
• Current models of pulmonary fibrosis for future drug discovery efforts  Journal Articles
• Customized Viral Immunotherapy for HPV-Associated Cancer  Journal Articles
• Cytokine and eosinophil responses in the lung, peripheral blood, and bone marrow compartments in a murine model of allergen-induced airways inflammation.  Journal Articles
• Cytokine expression by neutrophils and macrophages in vivo: endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1 beta, and interleukin-6 but not RANTES or transforming growth factor-beta 1 mRNA expression in acute lung inflammation.  Journal Articles
• Cytokine-Based Therapy in Psoriasis  Journal Articles
• Cytokines and pulmonary inflammatory and immune diseases.  Journal Articles
• Cytosolic TDP-43 expression following axotomy is associated with caspase 3 activation in NFL−/− mice: Support for a role for TDP-43 in the physiological response to neuronal injury  Journal Articles
• D-Glucose transport in piglet jejunal brush-border membranes: insights from a disease model  Journal Articles
• DJ-1/PARK7 Impairs Bacterial Clearance in Sepsis  Journal Articles
• Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism.  Journal Articles
• Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease  Journal Articles
• Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis  Journal Articles
• Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid  Journal Articles
• Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts  Journal Articles
• Defects in neuromuscular junction remodelling in the Smn(2B/-) mouse model of spinal muscular atrophy.  Journal Articles
• Delayed Onset of Changes in Soma Action Potential Genesis in Nociceptive A-Beta DRG Neurons in Vivo in a Rat Model of Osteoarthritis  Journal Articles
• Delayed but not Early Treatment with DNase Reduces Organ Damage and Improves Outcome in a Murine Model of Sepsis  Journal Articles
• Deleting Rac1 improves vertebral bone quality and resistance to fracture in a murine ovariectomy model  Journal Articles
• Deletion of Macrophage-Specific Glycogen Synthase Kinase (GSK)-3α Promotes Atherosclerotic Regression in Ldlr−/− Mice  Journal Articles
• Deletion of Myeloid GSK3α Attenuates Atherosclerosis and Promotes an M2 Macrophage Phenotype  Journal Articles
• Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice  Journal Articles
• Demyelination in a transgenic mouse: A model for multiple sclerosis  Journal Articles
• Dendritic Arborization and Spine Dynamics Are Abnormal in the Mouse Model ofMECP2Duplication Syndrome  Journal Articles
• Depressive-Like Parameters in Sepsis Survivor Rats  Journal Articles
• Design and validation of an assessment tool for open surgical procedures  Journal Articles
• Detection of Lung Dysfunction Using Ventilation and Perfusion SPECT in a Mouse Model of Chronic Cigarette Smoke Exposure  Journal Articles
• Detection of hemorrhagic and axonal pathology in mild traumatic brain injury using advanced MRI: Implications for neurorehabilitation  Journal Articles
• Determinants of the immune-inflammatory response in allergic airway inflammation: Overview of antigen presentation and cellular activation  Journal Articles
• Development and temporal organization of compulsive checking induced by repeated injections of the dopamine agonist quinpirole in an animal model of obsessive-compulsive disorder  Journal Articles
• Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD  Journal Articles
• Development of a Murine Model of Early Sepsis in Diet-Induced Obesity  Journal Articles
• Development of a Patient-Derived Xenograft Model Using Brain Tumor Stem Cell Systems to Study Cancer  Journal Articles
• Diannexin, an annexin A5 homodimer, binds phosphatidylserine with high affinity and is a potent inhibitor of platelet‐mediated events during thrombus formation  Journal Articles
• Differences Between Murine and Human Sepsis  Journal Articles
• Differences in electrophysiological properties of functionally identified nociceptive sensory neurons in an animal model of cancer-induced bone pain  Journal Articles
• Differential Expression of PCSK9 Modulates Infection, Inflammation, and Coagulation in a Murine Model of Sepsis  Journal Articles
• Differential Role of B Cells and IL-17 Versus IFN-γ During Early and Late Rejection of Pig Islet Xenografts in Mice  Journal Articles
• Differential actions of nerve growth factor receptors TrkA and p75NTR in a rat model of epileptogenesis  Journal Articles
• Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease  Journal Articles
• Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer’s disease-associated markers in 3xTg-AD mice  Journal Articles
• Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation  Journal Articles
• Differential expression and interaction of melatonin and thyroid hormone receptors with estrogen receptor α improve ovarian functions in letrozole-induced rat polycystic ovary syndrome  Journal Articles
• Differentiation of bone marrow-derived cells into regenerated mesothelial cells in peritoneal remodeling using a peritoneal fibrosis mouse model  Journal Articles
• Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis  Journal Articles
• Discerning the Complexity of Community Interactions Using a Drosophila Model of Polymicrobial Infections  Journal Articles
• Discovery of Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for Live-Cell and In Vivo Imaging  Journal Articles
• Discovery of a structural class of antibiotics with explainable deep learning  Journal Articles
• Disruption of CD40-CD40 ligand pathway inhibits the development of intestinal muscle hypercontractility and protective immunity in nematode infection  Journal Articles
• Disruption of T-cell immunoglobulin and mucin domain molecule (TIM)–1/TIM4 interaction as a therapeutic strategy in a dendritic cell–induced peanut allergy model  Journal Articles
• Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice  Journal Articles
• Dissociating basal forebrain and medial temporal amnesic syndromes: Insights from classical conditioning  Journal Articles
• Distinctive Roles and Mechanisms of Human Neutrophil Peptides in Experimental Sepsis and Acute Respiratory Distress Syndrome  Journal Articles
• Distribution and prevalence of leukocyte phenotypes in brains of lupus-prone mice  Journal Articles
• Does Compromised Immune Exclusion Drive Inflammatory Processes in Chronic Obstructive Pulmonary Disease?  Journal Articles
• Dose threshold for radiation induced fetal programming in a mouse model at 4 months of age: Hepatic expression of genes and proteins involved in glucose metabolism and glucose uptake in brown adipose tissue  Journal Articles
• Downregulation of BM88 After Optic Nerve Injury  Journal Articles
• Dramatically Different Phenotypes in Mouse Models of Human Tay-Sachs and Sandhoff Diseases  Journal Articles
• Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma  Journal Articles
• Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2  Journal Articles
• Duration of binocular decorrelation in infancy predicts the severity of nasotemporal pursuit asymmetries in strabismic macaque monkeys  Journal Articles
• EFFECT OF TEMPORARY TRACHEAL OCCLUSION ON THE ENDOTHELIN SYSTEM IN EXPERIMENTAL CASES OF DIAPHRAGMATIC HERNIA  Conferences
• Early Intervention with a Multi-Ingredient Dietary Supplement Improves Mood and Spatial Memory in a Triple Transgenic Mouse Model of Alzheimer’s Disease  Journal Articles
• Early life stress decreases hippocampal BDNF content and exacerbates recognition memory deficits induced by repeated d-amphetamine exposure  Journal Articles
• Early morphometric and anisotropic change in periarticular cancellous bone in a model of experimental knee osteoarthritis quantified using microcomputed tomography  Journal Articles
• Early myopathy in Duchenne muscular dystrophy is associated with elevated mitochondrial H₂O₂ emission during impaired oxidative phosphorylation  Journal Articles
• Early regional cuprizone‐induced demyelination in a rat model revealed with MRI  Journal Articles
• Early ultrastructural and biochemical changes in the myopathic hamster heart.  Journal Articles
• Ecobiotherapy Rich in Firmicutes Decreases Susceptibility to Colitis in a Humanized Gnotobiotic Mouse Model  Journal Articles
• Ecology of Danger‐dependent Cytokine‐boosted Spontaneous Abortion in the CBA × DBA/2 Mouse Model. I. Synergistic Effect of LPS and (TNF‐α + IFN‐γ) on Pregnancy Loss  Journal Articles
• Effect of Different Doses of Acetylsalicylic Acid on the Antithrombotic Activity of Clopidogrel in a Mouse Arterial Thrombosis Model  Journal Articles
• Effect of Interferon-γon Allergic Airway Responses in Interferon-γ–deficient Mice  Journal Articles
• Effect of Leptin on Vascular Calcification in Apolipoprotein E–Deficient Mice  Journal Articles
• Effect of Limited and Standard Reaming on Cortical Bone Blood Flow and Early Strength of Union Following Segmental Fracture  Journal Articles
• Effect of Nicotine Exposure During Pregnancy and Lactation on Maternal, Fetal, and Postnatal Rat IGF-II Profile  Journal Articles
• Effect of Oxidative Stress on Brain Damage Detected by MRI and in vivo 31P-NMR  Journal Articles
• Effect of Purified Lipopolysaccharides from Strains of Helicobacter pylori and Helicobacter felis on Acid Secretion in Mouse Gastric Glands In Vitro  Journal Articles
• Effect of Unreamed, Limited Reamed, and Standard Reamed Intramedullary Nailing on Cortical Bone Porosity and New Bone Formation  Journal Articles
• Effect of bromocriptine alginate nanocomposite (BANC) on a transgenic Drosophila model of Parkinson's disease  Journal Articles
• Effect of covalent antithrombin-heparin complex on developmental mechanisms in the lung  Journal Articles
• Effect of cyclophosphamide on leukocytic infiltration in the brain of MRL/lpr mice  Journal Articles
• Effect of dexamethasone on antigen-induced high molecular weight glycoconjugate secretion in allergic guinea pigs.  Journal Articles
• Effect of interferon-γ on allergic airway responses in interferon-γ-deficient mice  Journal Articles
• Effect of nicotine on quinpirole-induced checking behavior in rats: implications for obsessive-compulsive disorder  Journal Articles
• Effect of zoledronic acid on the doxycycline-induced decrease in tumour burden in a bone metastasis model of human breast cancer  Journal Articles
• Effects in the use of a genetically engineered strain ofLactococcus lactisdelivering in situ IL-10 as a therapy to treat low-grade colon inflammation  Journal Articles
• Effects of Intravenously Administered Recombinant Vesicular Stomatitis Virus (VSV ΔM51 ) on Multifocal and Invasive Gliomas  Journal Articles
• Effects of Kaixin Jieyu Decoction (开心解郁汤) on behavior and glial fibrillary acidic protein expression in cerebral hippocampus of a rat vascular depression model  Journal Articles
• Effects of MK-801 treatment across several pre-clinical analyses including a novel assessment of brain metabolic function utilizing PET and CT fused imaging in live rats  Journal Articles
• Effects of Nebulized Diethylenetetraamine-NONOate in a Mouse Model of Acute Pseudomonas aeruginosa Pneumonia  Journal Articles
• Effects of Obesity-Associated Chronic Inflammation on Peripheral Blood Immunophenotype Are Not Mediated by TNF in Female C57BL/6J Mice  Journal Articles
• Effects of Taurine Supplementation on Hepatic Markers of Inflammation and Lipid Metabolism in Mothers and Offspring in the Setting of Maternal Obesity  Journal Articles
• Effects of activated protein C on the mesenteric microcirculation and cytokine release during experimental endotoxemia  Journal Articles
• Effects of allergen on airway narrowing dynamics as assessed by lung-slice technique  Journal Articles
• Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania  Journal Articles
• Effects of chronic hypoxia on diaphragm function in deer mice native to high altitude  Journal Articles
• Effects of dopexamine on the intestinal microvascular blood flow and leukocyte activation in a sepsis model in rats.  Journal Articles
• Effects of flaxseed and flax oil diets in a rat-5/6 renal ablation model  Journal Articles
• Effects of fluoxetine on mast cell morphology and protease-1 expression in gastric antrum in a rat model of depression  Journal Articles
• Effects of furosemide on allergic asthmatic responses in mice  Journal Articles
• Effects of heparin, its low molecular weight fractions and other glycosaminoglycans on thrombus growth  Journal Articles
• Effects of high‐intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis  Journal Articles
• Effects of hypophysectomy on compulsive checking and cortical dendrites in an animal model of obsessive-compulsive disorder  Journal Articles
• Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania.  Journal Articles
• Effects of lithium and valproate on hippocampus citrate synthase activity in an animal model of mania  Journal Articles
• Effects of lithium and valproate on serum and hippocampal neurotrophin-3 levels in an animal model of mania  Journal Articles
• Effects of mood stabilizers on hippocampus BDNF levels in an animal model of mania  Journal Articles
• Effects of mood stabilizers on hippocampus and amygdala BDNF levels in an animal model of mania induced by ouabain  Journal Articles
• Effects of mood stabilizers on mitochondrial respiratory chain activity in brain of rats treated with d-amphetamine  Journal Articles
• Effects of prenatal immune activation on amphetamine-induced addictive behaviors: Contributions from animal models  Journal Articles
• Effects of sustained i.c.v. infusion of lupus CSF and autoantibodies on behavioral phenotype and neuronal calcium signaling  Journal Articles
• Effects of the serotonergic agonist mCPP on male rats in the quinpirole sensitization model of obsessive–compulsive disorder (OCD)  Journal Articles
• Effects of treadmill exercise on cyclooxygenase-2 in the hippocampus in type 2 diabetic rats: Correlation with the neuroblasts  Journal Articles
• Effects of variable blast pressures on blood flow and oxygen saturation in rat brain as evidenced using MRI  Journal Articles
• Effects of β-carboline harmine on behavioral and physiological parameters observed in the chronic mild stress model: Further evidence of antidepressant properties  Journal Articles
• Efficacy of gene-therapy based on adenovirus encoding granulocyte-macrophage colony-stimulating factor in drug-sensitive and drug-resistant experimental pulmonary tuberculosis  Journal Articles
• Electrical muscle stimulation after immediate nerve repair reduces muscle atrophy without affecting reinnervation  Journal Articles
• Electrical muscle stimulation elevates intramuscular BDNF and GDNF mRNA following peripheral nerve injury and repair in rats  Journal Articles
• Electromyographic telemetry in the development of humane primate model of spinal cord injury  Journal Articles
• Electron spin resonance spectroscopy reveals alpha‐phenyl‐N‐tert‐butylnitrone spin‐traps free radicals in rat striatum and prevents haloperidol‐induced vacuous chewing movements in the rat model of human tardive dyskinesia  Journal Articles
• Encapsulated engineered myoblasts can cure Hurler syndrome: preclinical experiments in the mouse model  Journal Articles
• Encapsulation for Somatic Gene Therapy  Conferences
• Endocrine Toxicants Including 2,3,7,8-Terachlorodibenzo-p-Dioxin (TCDD) and Dioxin-like Chemicals and Endometriosis: Is There A Link?  Journal Articles
• Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis  Journal Articles
• Endoplasmic reticulum stress inhibition attenuates hypertensive chronic kidney disease through reduction in proteinuria  Journal Articles
• Endoplasmic reticulum stress inhibition blunts the development of essential hypertension in the spontaneously hypertensive rat  Journal Articles
• Endoplasmic reticulum stress inhibition limits the progression of chronic kidney disease in the Dahl salt-sensitive rat  Journal Articles
• Endothelial dysfunction drives atherosclerotic plaque macrophage-dependent abdominal aortic aneurysm formation.  Journal Articles
• Endovascular Shear Strain Elastography for the Detection and Characterization of the Severity of Atherosclerotic Plaques: In Vitro Validation and In Vivo Evaluation  Journal Articles
• Endpoints in myelin-deficient (MD) rats.  Journal Articles
• Engineered Nanoparticle Applications for Recombinant Influenza Vaccines  Journal Articles
• Enhanced Lipid Oxidation and Maintenance of Muscle Insulin Sensitivity Despite Glucose Intolerance in a Diet-Induced Obesity Mouse Model  Journal Articles
• Enhancement of Antituberculosis Immunity in a Humanized Model System by a Novel Virus-Vectored Respiratory Mucosal Vaccine  Journal Articles
• Enhancing Immune Responses to Cancer Vaccines Using Multi-Site Injections  Journal Articles
• Enteric glia promote regeneration of transected dorsal root axons into spinal cord of adult rats  Journal Articles
• Environmental Dioxins and Endometriosis  Journal Articles
• Eosinophil-derived IL-13 promotes emphysema  Journal Articles
• Eosinophilia in antigen-induced airways inflammation.  Journal Articles
• Eosinophilopoiesis in A Murine Model of Allergic Airway Eosinophilia: Involvement of Bone Marrow IL-5 and IL-5 Receptor α  Journal Articles
• Eosinophils Are Dispensable for Allergic Remodeling and Immunity in a Model of House Dust Mite–induced Airway Disease  Journal Articles
• Eosinophils and T Lymphocytes Possess Distinct Roles in Bleomycin-Induced Lung Injury and Fibrosis  Journal Articles
• Epigenetic therapy inhibits metastases by disrupting premetastatic niches  Journal Articles
• Epigenetics of Sepsis  Journal Articles
• Epithelial–stromal interaction increases cell proliferation, survival and tumorigenicity in a mouse model of human epithelial ovarian cancer  Journal Articles
• Erythrocyte deformability is a nitric oxide-mediated factor in decreased capillary density during sepsis  Journal Articles
• Establishment in Severe Combined Immunodeficiency Mice of Subrenal Capsule Xenografts and Transplantable Tumor Lines from a Variety of Primary Human Lung Cancers: Potential Models for Studying Tumor Progression–Related Changes  Journal Articles
• Establishment of T‐Helper‐2 immune response based gerbil model of enteric infection  Journal Articles
• Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway  Journal Articles
• Estradiol Regulates Susceptibility following Primary Exposure to Genital Herpes Simplex Virus Type 2, while Progesterone Induces Inflammation  Journal Articles
• Ethanol during adolescence decreased the BDNF levels in the hippocampus in adult male Wistar rats, but did not alter aggressive and anxiety-like behaviors  Journal Articles
• Evaluating the evidence for macrophage presence in skeletal muscle and its relation to insulin resistance in obese mice and humans: a systematic review protocol  Journal Articles
• Evaluation of Inducible Costimulator/B7-Related Protein-1 as a Therapeutic Target in a Murine Model of Allergic Airway Inflammation  Journal Articles
• Evidence Supporting a Role for Endoplasmic Reticulum Stress in the Development of Atherosclerosis in a Hyperglycaemic Mouse Model  Journal Articles
• Evidence of extensive atherosclerosis, coronary artery disease and myocardial infarction in the ApoE−/−:Ins2 mouse fed a western diet  Journal Articles
• Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling  Journal Articles
• Evolving Concepts in the Pathophysiology of Functional Gastrointestinal Disorder  Journal Articles
• Evolving pathophysiologic models of functional gastrointestinal disorders  Journal Articles
• Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours  Journal Articles
• Examining the effect of chronic intranasal oxytocin administration on the neuroanatomy and behavior of three autism-related mouse models  Journal Articles
• Examining tissue-level changes in doxorubicin accumulation and nitric oxide formation in skeletal muscle and tumours in a mouse model of breast cancer.  Journal Articles
• Excitability of Aβ sensory neurons is altered in an animal model of peripheral neuropathy  Journal Articles
• Exercise Improves Cancer-free Survival and Health Span in a Model of Radiation-induced Cancer  Journal Articles
• Exercise training enhances the skeletal muscle response to radiation‐induced oxidative stress  Journal Articles
• Expansive Generation of Functional Airway Epithelium From Human Embryonic Stem Cells  Journal Articles
• Experience-dependent central vision deficits: Neurobiology and visual acuity  Journal Articles
• Experience-dependent changes in NMDAR1 expression in the visual cortex of an animal model for amblyopia  Journal Articles
• Experimental models of chronic subdural hematoma.  Journal Articles
• Exploiting the fitness cost of metallo-β-lactamase expression can overcome antibiotic resistance in bacterial pathogens.  Journal Articles
• Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity  Journal Articles
• Extracellular RNA Sensing Mediates Inflammation and Organ Injury in a Murine Model of Polytrauma.  Journal Articles
• Factor XIII Prevents Pulmonary Emboli in Mice by Stabilizing Deep Vein Thrombi  Journal Articles
• Factors influencing therapeutic efficacy and the host immune response to helper‐dependent adenoviral gene therapy in hemophilia A mice  Journal Articles
• Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model  Journal Articles
• Familial dysmyelination in a Long Evans rat mutant.  Journal Articles
• Fc Gamma Receptor Signaling in Mast Cells Links Microbial Stimulation to Mucosal Immune Inflammation in the Intestine  Journal Articles
• Features of compulsive checking behavior mediated by nucleus accumbens and orbital frontal cortex  Journal Articles
• Fetal and neonatal exposure to nicotine in Wistar rats results in increased beta cell apoptosis at birth and postnatal endocrine and metabolic changes associated with type 2 diabetes  Journal Articles
• Fibrinogen catabolism within the procoagulant VX-2 tumor of rabbit lung in vivo: effluxing fibrin(ogen) fragments contain antiangiogenic activity  Journal Articles
• Fibrotic extracellular matrix induces release of extracellular vesicles with pro-fibrotic miRNA from fibrocytes  Journal Articles
• First trial motor seizures triggered by amygdaloid stimulation in the rat  Journal Articles
• Folic acid prevented cognitive impairment in experimental pneumococcal meningitis  Journal Articles
• Follistatin lowers blood pressure and improves vascular structure and function in essential and secondary hypertension.  Journal Articles
• Frequency of Human CD45+ Target Cells is a Key Determinant of Intravaginal HIV-1 Infection in Humanized Mice  Journal Articles
• From Mosquito Bites to Sexual Transmission: Evaluating Mouse Models of Zika Virus Infection  Journal Articles
• Functional Changes in Muscle Afferent Neurones in an Osteoarthritis Model: Implications for Impaired Proprioceptive Performance  Journal Articles
• Functional MR imaging of the porcine kidney: physiologic changes of prolonged pneumoperitoneum.  Journal Articles
• Functional Roles for C5a and C5aR but Not C5L2 in the Pathogenesis of Human and Experimental Cerebral Malaria  Journal Articles
• Functional profiling of murine glioma models highlights targetable immune evasion phenotypes.  Journal Articles
• Fusion to Human Serum Albumin Extends the Circulatory Half-Life and Duration of Antithrombotic Action of the Kunitz Protease Inhibitor Domain of Protease Nexin 2  Journal Articles
• G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.  Journal Articles
• GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism  Journal Articles
• GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia  Journal Articles
• Gamma Interferon Responses of CD4 and CD8 T-Cell Subsets Are Quantitatively Different and Independent of Each Other during PulmonaryMycobacterium bovisBCG Infection  Journal Articles
• Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer  Journal Articles
• Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice  Journal Articles
• Gastrointestinal food hypersensitivity: Basic mechanisms of pathophysiology  Journal Articles
• Gene Therapy, A Targeted Treatment for Diabetic Nephropathy  Journal Articles
• Gene therapy for murine mucopolysaccharidosis type VII  Conferences
• Generation of Murine Xenograft Models of Brain Tumors from Primary Human Tissue for In Vivo Analysis of the Brain Tumor-Initiating Cell  Journal Articles
• Generation of experimental allergic airways inflammation in the absence of draining lymph nodes  Journal Articles
• Genetic and Chemical Screening in Human Blood Serum Reveals Unique Antibacterial Targets and Compounds against Klebsiella pneumoniae  Journal Articles
• Genetic elimination of eNOS reduces secondary complications of experimental subarachnoid hemorrhage.  Journal Articles
• Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity  Journal Articles
• Genomic responses in mouse models poorly mimic human inflammatory diseases  Journal Articles
• Gestational exposure to Δ⁹-THC impacts ovarian follicular dynamics and angiogenesis in adulthood in Wistar rats  Journal Articles
• Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice  Journal Articles
• Global analyses of gene expression in early experimental osteoarthritis  Journal Articles
• Glucagon-like peptide-2-enhanced barrier function reduces pathophysiology in a model of food allergy  Journal Articles
• Glucocorticoid Receptor Changes Associate with Age in the Paraventricular Nucleus of Type II Diabetic Rat Model  Journal Articles
• Glucocorticoid-induced osteoporosis  Journal Articles
• Gluten-Dependent Activation of CD4+ T Cells by MHC Class II–Expressing Epithelium  Journal Articles
• Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells  Journal Articles
• Glycosphingolipids promote pro-atherogenic pathways in the pathogenesis of hyperglycemia-induced accelerated atherosclerosis  Journal Articles
• Glycosyltransferases and Glycosaminoglycans in Bleomycin and Transforming Growth Factor-β1–Induced Pulmonary Fibrosis  Journal Articles
• GnRH antagonist associates with less adiposity and reduced characteristics of metabolic syndrome and atherosclerosis compared with orchiectomy and GnRH agonist in a preclinical mouse model1Contributed equally and share first authorship.  Journal Articles
• Goats Primed with Mycobacterium bovis BCG and Boosted with a Recombinant Adenovirus Expressing Ag85A Show Enhanced Protection against Tuberculosis  Journal Articles
• Gob-5 Is Not Essential for Mucus Overproduction in Preclinical Murine Models of Allergic Asthma  Journal Articles
• Goblet Cell Rebound and Airway Dysfunction with Corticosteroid Withdrawal in a Mouse Model of Asthma  Journal Articles
• Governing role of primary afferent drive in increased excitation of spinal nociceptive neurons in a model of sciatic neuropathy  Journal Articles
• Grain‐sized moxibustion promotes NK cell antitumour immunity by inhibiting adrenergic signalling in non–small cell lung cancer  Journal Articles
• Gremlin Promotes Peritoneal Membrane Injury in an Experimental Mouse Model and Is Associated with Increased Solute Transport in Peritoneal Dialysis Patients  Journal Articles
• Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: A comparative study in gene‐deficient mice  Journal Articles
• Gut Microbial and Metabolic Responses to Salmonella enterica Serovar Typhimurium and Candida albicans  Journal Articles
• Gut bacteria interact directly with colonic mast cells in a humanized mouse model of IBS  Journal Articles
• HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner  Journal Articles
• HSV-2 vaccine: Current state and insights into development of a vaccine that targets genital mucosal protection  Journal Articles
• Haemopoietic mechanisms in murine allergic upper and lower airway inflammation  Journal Articles
• Handling of the Cotton Rat in Studies for the Pre-clinical Evaluation of Oncolytic Viruses  Journal Articles
• Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling  Journal Articles
• Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A  Journal Articles
• Hemagglutinin Stalk Immunity Reduces Influenza Virus Replication and Transmission in Ferrets  Journal Articles
• Hematological Effects, Serum, and Pulmonary Cytokine Profiles in a Melanoma Mouse Model Treated with GK1  Journal Articles
• Heparin Improves Gas Exchange during Experimental Acute Lung Injury in Newborn Piglets  Journal Articles
• Heparin compromises streptokinase-induced arterial patency in rabbits  Journal Articles
• Heparin-induced thrombocytopenia: a historical perspective  Journal Articles
• Hepatitis C Virus-Induced Degradation of Cell Death-Inducing DFFA-Like Effector B Leads to Hepatic Lipid Dysregulation.  Journal Articles
• Hepatocyte growth factor modulates the hepatic acute-phase response in thermally injured rats  Journal Articles
• Heroin "Overdose" Death: Contribution of Drug-Associated Environmental Cues  Journal Articles
• Heterogeneity of the immune response to adenovirus‐mediated factor VIII gene therapy in different inbred hemophilic mouse strains  Journal Articles
• Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells  Journal Articles
• High and low pressure irrigation in contaminated wounds with exposed bone.  Journal Articles
• High salt diet exacerbates colitis in mice by decreasing Lactobacillus levels and butyrate production  Journal Articles
• High-Grade Glioma Formation Results from Postnatal Pten Loss or Mutant Epidermal Growth Factor Receptor Expression in a Transgenic Mouse Glioma Model  Journal Articles
• High-Resolution Longitudinal Screening with Magnetic Resonance Imaging in a Murine Brain Cancer Model  Journal Articles
• Hippocampal damage in mouse and human forms of systemic autoimmune disease  Journal Articles
• Hippocampal neuronal subtypes develop abnormal dendritic arbors in the presence of Fragile X astrocytes  Journal Articles
• Histidine-Rich Glycoprotein Modulates the Toxic Effects of High-Dose Polyphosphate in Mice  Journal Articles
• Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania  Journal Articles
• Host Defense Peptide Resistance Contributes to Colonization and Maximal Intestinal Pathology by Crohn's Disease-Associated Adherent-Invasive Escherichia coli  Journal Articles
• Host-Specific Adaptive Diversification of Crohn’s Disease-Associated Adherent-Invasive Escherichia coli  Journal Articles
• How useful is traditional herbal medicine for pulmonary fibrosis?  Journal Articles
• Hsp72 preserves muscle function and slows progression of severe muscular dystrophy  Journal Articles
• Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP  Journal Articles
• Human antigen R promotes lung fibroblast differentiation to myofibroblasts and increases extracellular matrix production  Journal Articles
• Human mesenchymal stem cells attenuate early damage in a ventilated pig model of acute lung injury  Journal Articles
• Human vaginal microbiota colonization is regulated by female sex hormones in a mouse model  Journal Articles
• Human-fecal microbiota transplantation in relation to gut microbiome signatures in animal models for schizophrenia: A scoping review.  Journal Articles
• Humanized mice are susceptible to Salmonella typhi infection  Journal Articles
• Humanized mice forSalmonellatyphiinfection: new tools for an old problem  Journal Articles
• Humanized mouse models of KRAS-mutated colorectal and pancreatic cancers with HLA-class-I match for pre-clinical evaluation of cancer immunotherapies.  Journal Articles
• Huntingtin N17 domain is a reactive oxygen species sensor regulating huntingtin phosphorylation and localization  Journal Articles
• Hydrophobically-modified poly(vinyl pyrrolidone) as a physically-associative, shear-responsive ophthalmic hydrogel  Journal Articles
• Hyperglycaemia is associated with impaired vasa vasorum neovascularization and accelerated atherosclerosis in apolipoprotein-E deficient mice  Journal Articles
• Hyperglycemia promotes insulin-independent ovarian tumor growth  Journal Articles
• Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice  Journal Articles
• Hypermetabolic Syndrome as a Consequence of Repeated Psychological Stress in Mice  Journal Articles
• Hyperplastic effects of aerosolized sodium metabisulfite on rat airway mucus-secretory epithelial cells  Journal Articles
• Hypertrophic scarring: the greatest unmet challenge after burn injury  Journal Articles
• Hypobaria Exposure Worsens Cardiac Function and Endothelial Injury in AN Animal Model of Polytrauma: Implications for Aeromedical Evacuation.  Journal Articles
• Hypoxia Alters The Expression of Inhibitor of Apoptosis Proteins after Brain Trauma in The Mouse  Journal Articles
• IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis  Journal Articles
• IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke–induced Lymphoid Neogenesis  Journal Articles
• IL-17A and the Promotion of Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease  Journal Articles
• IL-4Rα blockade reduces influenza-associated morbidity in a murine model of allergic asthma  Journal Articles
• IL-9+ IL-10+ T cells link immediate allergic response to late phase reaction  Journal Articles
• IL‐25 promotes cisplatin resistance of lung cancer cells by activating NF‐κB signaling pathway to increase of major vault protein  Journal Articles
• IMI – Report on Experimental Models of Emmetropization and Myopia  Journal Articles
• INSULIN ATTENUATES THE CYTOKINE RESPONSE IN A BURN WOUND INFECTION MODEL  Journal Articles
• INVESTIGATION OF THE PATHOLOGICAL EFFECTS OF HISTONES, DNA, AND NUCLEOSOMES IN A MURINE MODEL OF SEPSIS  Journal Articles
• Ibuprofen fails to prevent brain pathology in a model of neuropsychiatric lupus.  Journal Articles
• Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer  Journal Articles
• Identification of Myopia-Related Marker Proteins in Tilapia Retinal, RPE, and Choroidal Tissue following Induced Form Deprivation  Journal Articles
• Identification of novel interacting protein partners of SMN using tandem affinity purification.  Journal Articles
• Identification of periplakin as a major regulator of lung injury and repair in mice  Journal Articles
• Image-Guided Perforator Flap Design Using Invisible Near-Infrared Light and Validation With X-Ray Angiography  Journal Articles
• Immune Stimulation Using a Gut Microbe-Based Immunotherapy Reduces Disease Pathology and Improves Barrier Function in Ulcerative Colitis  Journal Articles
• Immune-mediated neural dysfunction in a murine model of chronic Helicobacter pylori infection  Journal Articles
• Immuno-Isolation in Cancer Gene Therapy  Journal Articles
• Immunogenic HSV-mediated Oncolysis Shapes the Antitumor Immune Response and Contributes to Therapeutic Efficacy  Journal Articles
• Immunomodulatory Effects of Heated Ovomucoid-Depleted Egg White in a BALB/c Mouse Model of Egg Allergy  Journal Articles
• Immunotherapeutic effects of recombinant adenovirus encoding granulocyte–macrophage colony-stimulating factor in experimental pulmonary tuberculosis  Journal Articles
• Impact of CD40 Ligand, B Cells, and Mast Cells in Peanut-Induced Anaphylactic Responses  Journal Articles
• Impact of Treadmill Running and Sex on Hippocampal Neurogenesis in the Mouse Model of Amyotrophic Lateral Sclerosis  Journal Articles
• Impact of inflammation, emphysema, and smoking cessation on V/Q in mouse models of lung obstruction  Journal Articles
• Impaired Growth and Force Production in Skeletal Muscles of Young Partially Pancreatectomized Rats: A Model of Adolescent Type 1 Diabetic Myopathy?  Journal Articles
• Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression  Journal Articles
• Impaired response to amphetamine and neuronal degeneration in the nucleus accumbens of autoimmune MRL-lpr mice  Journal Articles
• Impaired responses to gliadin and gut microbes of immune cells from mice with altered stress-related behavior and premature immune senescence  Journal Articles
• Improved adjuvanting of seasonal influenza vaccines: Preclinical studies of MVA‐NP+M1 coadministration with inactivated influenza vaccine  Journal Articles
• In Vitro and In Vivo Evaluation of Novel Ciprofloxacin-Releasing Silicone Hydrogel Contact Lenses  Journal Articles
• In Vivo Generation of Neural Tumors from Neoplastic Pluripotent Stem Cells Models Early Human Pediatric Brain Tumor Formation  Journal Articles
• In Vivo Murine Models of Brain Metastasis  Chapters
• In utero exposure to valproic acid and autism — A current review of clinical and animal studies  Journal Articles
• In vitro experiment to elucidate the mechanism of the ‘soft shell technique’ for preventing subretinal migration of perfluoro-octane  Journal Articles
• In vivo detection of macrophages in a rabbit atherosclerotic model by time-resolved laser-induced fluorescence spectroscopy  Journal Articles
• In vivo measurement of tissue damage, oxygen saturation changes and blood flow changes after experimental traumatic brain injury in rats using susceptibility weighted imaging  Journal Articles
• Inactivation of MuxABC-OpmB transporter system in Pseudomonas aeruginosa leads to increased ampicillin and carbenicillin resistance and decreased virulence  Journal Articles
• Increased Bacterial Translocation in Gluten-Sensitive Mice Is Independent of Small Intestinal Paracellular Permeability Defect  Journal Articles
• Increased Monocyte-Derived CD11b+ Macrophage Subpopulations Following Cigarette Smoke Exposure Are Associated With Impaired Bleomycin-Induced Tissue Remodelling  Journal Articles
• Increased Ornithine-Derived Polyamines Cause Airway Hyperresponsiveness in a Mouse Model of Asthma  Journal Articles
• Increased Pancreatic Beta-Cell Apoptosis following Fetal and Neonatal Exposure to Nicotine Is Mediated via the Mitochondria  Journal Articles
• Increased cerebrospinal fluid levels of S100B protein in rat model of mania induced by ouabain  Journal Articles
• Increased deposition of chondroitin/dermatan sulfate glycosaminoglycan and upregulation of β1,3-glucuronosyltransferase I in pulmonary fibrosis  Journal Articles
• Increased eosinophil-lineage committed progenitors in the lung of allergen-challenged mice  Journal Articles
• Increased expression of vascular cell adhesion molecule-1 by the aortic endothelium of rabbits with Pasteurella multocida pneumonia.  Journal Articles
• Induced Pluripotent Stem Cells to Model and Treat Neurogenetic Disorders  Journal Articles
• Induction of Innate Immunity against Herpes Simplex Virus Type 2 Infection via Local Delivery of Toll-Like Receptor Ligands Correlates with Beta Interferon Production  Journal Articles
• Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease.  Journal Articles
• Infection-Induced Thrombocytopenia  Journal Articles
• Inferior Vena Cava Ligation Rapidly Induces Tissue Factor Expression and Venous Thrombosis in Rats  Journal Articles
• Inflammatory Cytokines, Angiogenesis, and Fibrosis in the Rat Peritoneum  Journal Articles
• Inflammatory, hemostatic, and clinical changes in a baboon experimental model for heatstroke  Journal Articles
• Influence of Plate Design on Cortical Bone Perfusion and Fracture Healing in Canine Segmental Tibial Fractures  Journal Articles
• Inhibiting STAT3 in a murine model of human breast cancer-induced bone pain delays the onset of nociception  Journal Articles
• Inhibition of COX pathway in experimental myocardial infarction  Journal Articles
• Inhibition of COX pathway in experimental myocardial infarction.  Journal Articles
• Inhibition of Cyclooxygenase-2 Improves Cardiac Function in Myocardial Infarction  Journal Articles
• Inhibition of Defocus-Induced Myopia in Chickens  Journal Articles
• Inhibition of Marfan Syndrome Aortic Root Dilation by Losartan  Journal Articles
• Inhibition of histone deacetylation with vorinostat does not prevent tunicamycin-mediated acute kidney injury  Journal Articles
• Inhibitors of metallo-β-lactamases  Journal Articles
• Innate T-cell-derived IL-17A/F protects from bleomycin-induced acute lung injury but not bleomycin or adenoviral TGF-β1-induced lung fibrosis in mice.  Journal Articles
• Innate immunity in amyotrophic lateral sclerosis  Journal Articles
• Instituto Nacional de Ciência e Tecnologia em Medicina Translacional (INCT-TM): abordagens metodológicas  Journal Articles
• Insulin Treatment Improves Hepatic Morphology and Function Through Modulation of Hepatic Signals After Severe Trauma  Journal Articles
• Insulin increases resistance to burn wound infection-associated sepsis  Journal Articles
• Insulin‐like growth factor‐I analogue protects muscles of dystrophic mdx mice from contraction‐mediated damage  Journal Articles
• Interferon-λ Mediates Oral Tolerance and Inhibits Antigen-Specific, T-Helper 2 Cell–Mediated Inflammation in Mouse Intestine  Journal Articles
• Interleukin 13 and Serotonin: Linking the Immune and Endocrine Systems in Murine Models of Intestinal Inflammation  Journal Articles
• Interleukin‐5 deficient mice exhibit impaired host defence against challenge Trichinella spiralis infections  Journal Articles
• Interrupting reactivation of immunologic memory diverts the allergic response and prevents anaphylaxis  Journal Articles
• Intestinal epithelial barrier dysfunction and dendritic cell redistribution during early stages of inflammation in the rat: Role for TLR-2 and -4 blockage  Journal Articles
• Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw  Journal Articles
• Intracerebral Administration of BDNF Protects Rat Brain Against Oxidative Stress Induced by Ouabain in an Animal Model of Mania  Journal Articles
• Intraductal Adaptation of the 4T1 Mouse Model of Breast Cancer Reveals Effects of the Epithelial Microenvironment on Tumor Progression and Metastasis  Journal Articles
• Intragraft CD11b+IDO+ Cells Mediate Cardiac Allograft Tolerance by ECDI-Fixed Donor Splenocyte Infusions  Journal Articles
• Intralipid as Treatment for Recurrent Unexplained Abortion?  Journal Articles
• Intranasal Exposure of Mice to House Dust Mite Elicits Allergic Airway Inflammation via a GM-CSF-Mediated Mechanism  Journal Articles
• Intranasal Mucosal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances the Protection of BCG-Primed Guinea Pigs against Pulmonary Tuberculosis  Journal Articles
• Intratracheal Pulmonary Ventilation and Continuous Positive Airway Pressure in a Sheep Model of Severe Acute Respiratory Failure  Journal Articles
• Intratracheal Pulmonary Ventilation at Low Airway Pressures in a Ventilator-Induced Model of Acute Respiratory Failure Improves Lung Function and Survival  Journal Articles
• Intrauterine Tracheal Obstruction, a New Treatment for Congenital Diaphragmatic Hernia, Decreases Amniotic Fluid Sodium and Chloride Concentrations in the Fetal Lamb  Journal Articles
• Intravital Microscopy of the Murine Urinary Bladder Microcirculation  Journal Articles
• Introducing Critical Appraisal to studies of animal models investigating novel therapies in sepsis  Journal Articles
• Investigating Intestinal Inflammation in DSS-induced Model of IBD  Journal Articles
• Investigating the protective effects of estrogen on β-cell health and the progression of hyperglycemia-induced atherosclerosis  Journal Articles
• Investigation of the Gut Microbiome in Patients with Schizophrenia and Clozapine-Induced Weight Gain: Protocol and Clinical Characteristics of First Patient Cohorts  Journal Articles
• Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease  Journal Articles
• Is Fructose a Story of Mice but Not Men?  Journal Articles
• Is Irritable Bowel Syndrome a Low-Grade Inflammatory Bowel Disease?  Journal Articles
• Is Spontaneous Resorption in the DBA/2‐Mated CBA/J Mouse due to a Defect in “Seed” or in “Soil”?  Journal Articles
• Kainic acid lesion-induced nigral neuronal death  Journal Articles
• Ketamine alters behavior and decreases BDNF levels in the rat brain as a function of time after drug administration  Journal Articles
• Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats  Journal Articles
• Key aspects of papillomavirus infection influence the host cervicovaginal microbiome in a preclinical murine papillomavirus (MmuPV1) infection model  Journal Articles
• Kinase inhibitors modulate huntingtin cell localization and toxicity  Journal Articles
• Kindling  Journal Articles
• Kindling and status epilepticus models of epilepsy: rewiring the brain  Journal Articles
• Kindling mechanisms: Current progress on an experimental epilepsy model  Journal Articles
• Kindling: basic mechanisms and clinical validity  Journal Articles
• Kinetics of in vitro bronchoconstriction in an elastolytic mouse model of emphysema  Journal Articles
• LPS-induced lung tissue-resident trained innate immunity provides differential protection against pneumococci and SARS-CoV-2.  Journal Articles
• Lack of Effect of Methylene Blue in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis  Journal Articles
• Lack of MHC expression and retention of ultrastructural characteristics by xenograft transmissible venereal tumor cells in SCID mice  Journal Articles
• Lactobacilli Degrade Wheat Amylase Trypsin Inhibitors to Reduce Intestinal Dysfunction Induced by Immunogenic Wheat Proteins  Journal Articles
• Lactobacillus rhamnosus Ingestion Promotes Innate Host Defense in an Enteric Parasitic Infection  Journal Articles
• Lactoferrin Reduces Necrotizing Enterocolitis Severity by Upregulating Intestinal Epithelial Proliferation  Journal Articles
• Laparoscopic cryosurgery for hepatic tumors  Journal Articles
• Late onset Tay–Sachs disease in mice with targeted disruption of the Hexa gene: behavioral changes and pathology of the central nervous system  Journal Articles
• Left Ventricular Unloading Using Intra-aortic Entrainment Pumping Before Reperfusion Reduces Post-AMI Infarct Size.  Journal Articles
• Leukocyte urokinase plasminogen activator receptor and PSGL1 play a role in endogenous arterial fibrinolysis  Journal Articles
• Life-Threatening Thrombosis in Mice With Targeted Arg48-to-Cys Mutation of the Heparin-Binding Domain of Antithrombin  Journal Articles
• Limitation ofTrypanosoma bruceiparasitaemia results from density-dependent parasite differentiation and parasite killing by the host immune response  Journal Articles
• Linking Animal Models of Psychosis to Computational Models of Dopamine Function  Journal Articles
• Long-Distance Axonal Regeneration in the Filum Terminale of Adult Rats Is Regulated by Ependymal Cells  Journal Articles
• Long-term reduction of medial and intimal thickening in porcine saphenous vein grafts with a polyglactin biodegradable external sheath  Journal Articles
• Loss of SR-BI Expression Leads to the Early Onset of Occlusive Atherosclerotic Coronary Artery Disease, Spontaneous Myocardial Infarctions, Severe Cardiac Dysfunction, and Premature Death in Apolipoprotein E–Deficient Mice  Journal Articles
• Loss of dystrophin expression in skeletal muscle is associated with senescence of macrophages and endothelial cells  Journal Articles
• Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model.  Journal Articles
• Loss of the sphingolipid desaturase DEGS1 causes hypomyelinating leukodystrophy  Journal Articles
• Lost in Translation: The Gut Microbiota in Psychiatric Illness  Journal Articles
• Low Molecular Weight Heparin  Journal Articles
• Lung Development and Susceptibility to Ventilator-induced Lung Injury  Journal Articles
• Lung Epithelial CCAAT/Enhancer-binding Protein-β Is Necessary for the Integrity of Inflammatory Responses to Cigarette Smoke  Journal Articles
• Lung-Homing of Endothelial Progenitor Cells and Airway Vascularization Is Only Partially Dependant on Eosinophils in a House Dust Mite-Exposed Mouse Model of Allergic Asthma  Journal Articles
• Ly6C^hiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis  Journal Articles
• Lysyl Oxidase–Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor-β1–induced Pulmonary Fibrosis  Journal Articles
• MMP9 Differentially Regulates Proteins Involved in Actin Polymerization and Cell Migration during TGF-β-Induced EMT in the Lens  Journal Articles
• Macrophage Function and Its Impact on Atherosclerotic Lesion Composition, Progression, and Stability  Journal Articles
• Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo.  Journal Articles
• Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells  Journal Articles
• Magnesium interrelationships in ischemic heart disease: a review  Journal Articles
• Magnetic resonance imaging for detection and analysis of mouse phenotypes  Journal Articles
• Magnetic-field-driven targeting of exosomes modulates immune and metabolic changes in dystrophic muscle.  Journal Articles
• Maternal Obesity and Developmental Programming of Metabolic Disorders in Offspring: Evidence from Animal Models  Journal Articles
• Maternal undernutrition during pregnancy and lactation affects testicular morphology, the stages of spermatogenic cycle, and the testicular IGF-I system in adult offspring  Journal Articles
• Maternal undernutrition during pregnancy and lactation increases transcription factors, ETV5 and GDNF, and alters regulation of apoptosis and heat shock proteins in the testis of adult offspring in the rat  Journal Articles
• Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis  Journal Articles
• Matrix Metalloproteinase Inhibitors Suppress Transforming Growth Factor-β-Induced Subcapsular Cataract Formation  Journal Articles
• Matrix catabolism in arthritis: priming the guns with oncostatin M.  Journal Articles
• Measurement of platelet-associated IgG in animal models of immune and nonimmune thrombocytopenia  Journal Articles
• Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis  Conferences
• Mechanism of catheter thrombosis: comparison of the antithrombotic activities of fondaparinux, enoxaparin, and heparin in vitro and in vivo  Journal Articles
• Mechanisms Underlying the Maintenance of Muscle Hypercontractility in a Model of Postinfective Gut Dysfunction  Journal Articles
• Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma  Journal Articles
• Mechanisms involved in the metastasis of cancer to bone  Conferences
• Mechanisms of delayed anti-tuberculosis protection in the lung of parenteral BCG-vaccinated hosts: A critical role of airway luminal T cells  Journal Articles
• Mechanisms of microthrombi formation after experimental subarachnoid hemorrhage.  Journal Articles
• Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease  Journal Articles
• Medial prefrontal cortical synapsin II knock-down induces behavioral abnormalities in the rat: Examining synapsin II in the pathophysiology of schizophrenia  Journal Articles
• Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania  Journal Articles
• Mesenchymal stem cells for the treatment of neurodegenerative and psychiatric disorders  Journal Articles
• Metabolic dysfunction following weight regain compared to initial weight gain in a high-fat diet-induced obese mouse model  Journal Articles
• Metformin adapts its cellular effects to bioenergetic status in a model of metabolic dysfunction  Journal Articles
• Metformin increases peroxisome proliferator-activated receptor γ Co-activator-1α and utrophin a expression in dystrophic skeletal muscle  Journal Articles
• Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo  Journal Articles
• Metformin prevents the pathological browning of subcutaneous white adipose tissue  Journal Articles
• Methods for Assessing Serpins as Neuroprotective Therapeutics  Journal Articles
• Methods for studying experimental myocardial ischemic and reperfusion injury  Journal Articles
• MicroRNA expression pattern in different stages of nonalcoholic fatty liver disease.  Journal Articles
• MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity  Journal Articles
• Microbial Regulation of Enteric Eosinophils and Its Impact on Tissue Remodeling and Th2 Immunity  Journal Articles
• Microfluidic Devices for Automation of Assays on Drosophila Melanogaster for Applications in Drug Discovery and Biological Studies  Journal Articles
• Miglustat as a therapeutic agent: prospects and caveats  Journal Articles
• Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens  Journal Articles
• Minimally invasive multiphoton and harmonic generation imaging of extracellular matrix structures in lung airway and related diseases  Journal Articles
• Minimizing the risk of Q fever in the hospital setting.  Journal Articles
• Mitohormesis during advanced stages of Duchenne muscular dystrophy reveals a redox-sensitive creatine pathway that can be enhanced by the mitochondrial-targeting peptide SBT-20.  Journal Articles
• Model of traumatic spinal cord injury in Macaca fascicularis: similarity of experimental lesions created by epidural catheter to human spinal cord injury  Journal Articles
• Modeling Asthma in Mice  Journal Articles
• Modeling Responses to Respiratory House Dust Mite Exposure  Journal Articles
• Modeling the Initiation and Progression of Human Acute Leukemia in Mice  Journal Articles
• Modelling the human immune response: can mice be trusted?  Journal Articles
• Modelo experimental de tratamiento con extracto de semillas de uva, vino tinto y etanol del melanoma metastásico pulmonar  Journal Articles
• Modular pharmacology-based approach to identify hub genes and kernel pathways of taodan granules treated psoriasis  Journal Articles
• Modulating brain function with microbiota  Journal Articles
• Modulating progenitor accumulation attenuates lung angiogenesis in a mouse model of asthma  Journal Articles
• Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication  Journal Articles
• Molecular alterations in the hippocampus after experimental subarachnoid hemorrhage.  Journal Articles
• Molecular and Histological Analysis of a New Rat Model of Experimental Knee Osteoarthritis  Conferences
• Monkey business for hemophilia management  Journal Articles
• Morphologic characteristics of endometriosis in the mouse model: application to toxicology  Journal Articles
• Morphometric Analysis of Mouse Airways After Chronic Allergen Challenge  Journal Articles
• Mouse Models of Autism: Testing Hypotheses About Molecular Mechanisms  Journal Articles
• Mouse Models of Lung Fibrosis  Journal Articles
• Mouse behavioral mutants have neuroimaging abnormalities  Journal Articles
• Mouse is the new woman? Translational research in reproductive immunology  Journal Articles
• Mouse models for mitochondrial disease  Journal Articles
• Mouse models of cystathionine β‐synthase deficiency reveal significant threshold effects of hyperhomocysteinemia  Journal Articles
• Mouse models of immune dysfunction: their neuroanatomical differences reflect their anxiety-behavioural phenotype  Journal Articles
• MpzR98C arrests Schwann cell development in a mouse model of early-onset Charcot–Marie–Tooth disease type 1B  Journal Articles
• Muc2 Mucin and Nonmucin Microbiota Confer Distinct Innate Host Defense in Disease Susceptibility and Colonic Injury  Journal Articles
• Mucin Gene Deficiency in Mice Impairs Host Resistance to an Enteric Parasitic Infection  Journal Articles
• Mucosal Innate and Adaptive Immune Responses against Herpes Simplex Virus Type 2 in a Humanized Mouse Model  Journal Articles
• Mucosally Delivered Dendritic Cells Activate T Cells Independently of IL-12 and Endogenous APCs  Journal Articles
• Multifocal haemorrhagic brain damage following hypoxia and blood pressure lability: case report and rat model  Journal Articles
• Multiple genes in human 20q13 chromosomal region are involved in an advanced prostate cancer xenograft.  Journal Articles
• Multiple mouse biological loading and monitoring system for MRI  Journal Articles
• Murine Airway Luminal Antituberculosis Memory CD8 T Cells by Mucosal Immunization Are Maintained Via Antigen-Driven In Situ Proliferation, Independent of Peripheral T Cell Recruitment  Journal Articles
• Murine Trophoblast Failure and Spontaneous Abortion  Journal Articles
• Murine models of asthma  Journal Articles
• Muscle Perfusion after Intramedullary Nailing of the Canine Tibia  Conferences
• Muscle weakness and mitochondrial stress occur before severe metastasis in a novel mouse model of ovarian cancer cachexia  Journal Articles
• Muscle-specific overexpression of IGF-I improves E-C coupling in skeletal muscle fibers from dystrophic mdx mice  Journal Articles
• Myeloid GSK3α Deficiency Reduces Lesional Inflammation and Neovascularization during Atherosclerotic Progression.  Journal Articles
• Myocardial Infarction Following Atherosclerosis in Murine Models  Journal Articles
• Myocardial infarction size from serial CPK: variability of CPK serum entry ratio with size and model of infarction.  Journal Articles
• Myxoma virus derived immune modulating proteins, M-T7 and Serp-1, reduce early inflammation after spinal cord injury in the rat model  Journal Articles
• N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation  Journal Articles
• NET-EN treatment leads to delayed HSV-2 infection, enhanced mucin and T cell functions in the female genital tract when compared to DMPA in a preclinical mouse model.  Journal Articles
• NLRP3 Inflammasome Modulates Post-Burn Lipolysis and Hepatic Fat Infiltration via Fatty Acid Synthase  Journal Articles
• NLRP3 knockout enhances immune infiltration and inflammatory responses and improves survival in a burn sepsis model  Journal Articles
• Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis  Journal Articles
• Nasal Tissue Extraction Is Essential for Characterization of the Murine Upper Respiratory Tract Microbiota  Journal Articles
• Nebulisation of surfactants in an animal model of neonatal respiratory distress  Journal Articles
• Nerve Growth Factor Accelerates Seizure Development, Enhances Mossy Fiber Sprouting, and Attenuates Seizure-Induced Decreases in Neuronal Density in the Kindling Model of Epilepsy  Journal Articles
• Nerve constriction in the rat: model of neuropathic, surgical and central pain  Journal Articles
• Nervous System Lupus: Pathogenesis and Rationale for Therapy  Journal Articles
• Neural stem cell transplantation and melatonin treatment in a 6‐hydroxydopamine model of Parkinson’s disease  Journal Articles
• Neurodegeneration in autoimmune MRL-lpr mice as revealed by Fluoro Jade B staining  Journal Articles
• Neurologic and Histologic Tests Used to Measure Neuroprotective Effectiveness of Virus-Derived Immune-Modulating Proteins  Chapters
• Neuronal Nitric Oxide Synthase Is a Novel Biomarker for the Interstitial Cells of Cajal in Stress-Induced Diarrhea-Dominant Irritable Bowel Syndrome  Journal Articles
• Neuroprotection by valproic acid in an intrastriatal rotenone model of Parkinson’s disease  Journal Articles
• Neuroprotective effects of guanosine on stroke models in vitro and in vivo  Journal Articles
• New model of subconjunctival tumor development in rabbits  Journal Articles
• Nociceptive response to innocuous mechanical stimulation is mediated via myelinated afferents and NK-1 receptor activation in a rat model of neuropathic pain  Journal Articles
• Non-Host Factors Influencing Onset and Severity of Celiac Disease  Journal Articles
• Non-viral transfer approaches for the gene therapy of mucopolysaccharidosis type II (Hunter syndrome)  Conferences
• Nonautologous gene therapy with implantable devices  Journal Articles
• Nonexpanded Adipose Stromal Vascular Fraction Local Therapy on Peripheral Nerve Regeneration Using Allografts  Journal Articles
• Non‐Autologous Transplantation with Immuno‐isolation in Large Animals—A Review  Conferences
• Normal macromolecular clearance out of the ventricles is delayed in hydrocephalus  Journal Articles
• Novel 5-HT₇ receptor antagonists modulate intestinal immune responses and reduce severity of colitis  Journal Articles
• Novel Fecal Biomarkers That Precede Clinical Diagnosis of Ulcerative Colitis  Journal Articles
• Novel Murine Model of Pneumococcal Pneumonia: Use of Temperature as a Measure of Disease Severity To Compare the Efficacies of Moxifloxacin and Levofloxacin  Journal Articles
• Novel Roles of Cytoplasmic ICP0: Proteasome-Independent Functions of the RING Finger Are Required To Block Interferon-Stimulated Gene Production but Not To Promote Viral Replication  Journal Articles
• Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection  Journal Articles
• Novel players in coeliac disease pathogenesis: role of the gut microbiota  Journal Articles
• Nuclear transportation of exogenous epidermal growth factor receptor and androgen receptor via extracellular vesicles  Journal Articles
• Nucleus accumbens core and pathogenesis of compulsive checking  Journal Articles
• Nutritional hepatic steatosis and mortality after burn injury in rats  Journal Articles
• ORFV: A Novel Oncolytic and Immune Stimulating Parapoxvirus Therapeutic  Journal Articles
• ORIGINAL ARTICLE: Ecology of Danger‐Dependent Cytokine‐Boosted Spontaneous Abortion in the CBA × DBA/2 Mouse Model: II Fecal LPS Levels in Colonies with Different Basal Abortion Rates  Journal Articles
• ORIGINAL ARTICLE: Prevention of Spontaneous Abortion in the CBA × DBA/2 Mouse Model by Intravaginal TGF‐β and Local Recruitment of CD4⁺8⁺ FOXP3⁺ Cells  Journal Articles
• Obesity and muscle‐macrophage crosstalk in humans and mice: A systematic review  Journal Articles
• Object recognition memory and BDNF expression are reduced in young TgCRND8 mice  Journal Articles
• Obsessive-compulsive disorder: Insights from animal models  Journal Articles
• Ocular Gene Transfer of Active TGF-β Induces Changes in Anterior Segment Morphology and Elevated IOP in Rats  Journal Articles
• Oestradiol enhances tumour regression induced by B7-1/IL-2 adenoviral gene transfer in a murine model of breast cancer  Journal Articles
• On use of animal models  Journal Articles
• Oncolytic Orf virus licenses NK cells via cDC1 to activate innate and adaptive antitumor mechanisms and extends survival in a murine model of late-stage ovarian cancer  Journal Articles
• Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod‐induced psoriasis‐like inflammation  Journal Articles
• One Universal Common Endpoint in Mouse Models of Amyotrophic Lateral Sclerosis  Journal Articles
• Opposing Functions of Akt Isoforms in Lung Tumor Initiation and Progression  Journal Articles
• Opposing effects of acute and repeated nicotine exposure on boldness in zebrafish  Journal Articles
• Optimising experimental research in respiratory diseases: an ERS statement  Journal Articles
• Oral Treatment with Live Lactobacillus reuteri Inhibits the Allergic Airway Response in Mice  Journal Articles
• Oral infection of mice with Salmonella entericaserovar Typhimurium causes meningitis and infection of the brain  Journal Articles
• Original article Cellular mechanisms of white matter regeneration in an adult dysmyelinated rat model  Journal Articles
• Original article Subdural infusion of dexamethasone inhibits leukomyelitis after acute spinal cord injury in a rat model  Journal Articles
• Orthotopic, syngeneic mouse model to study the effects of epithelial-stromal interaction  Journal Articles
• Out‐FOX(O)ing proteolysis in sepsis  Journal Articles
• P2X7 Purinergic Receptor Is Involved in the Pathophysiology of Mania: a Preclinical Study  Journal Articles
• PAOPA, a potent analogue of Pro-Leu-glycinamide and allosteric modulator of the dopamine D2 receptor, prevents NMDA receptor antagonist (MK-801)-induced deficits in social interaction in the rat: Implications for the treatment of negative symptoms in schizophrenia  Journal Articles
• PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioral and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia  Journal Articles
• PDZK1 in leukocytes protects against cellular apoptosis and necrotic core development in atherosclerotic plaques in high fat diet fed ldl receptor deficient mice  Journal Articles
• PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R)  Journal Articles
• PLGA Nanoparticles Stabilized with Cationic Surfactant: Safety Studies and Application in Oral Delivery of Paclitaxel to Treat Chemical-Induced Breast Cancer in Rat  Journal Articles
• Pain Perception in Acute Model Mice of Parkinson's Disease Induced by 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)  Journal Articles
• Pan-Lysyl Oxidase Inhibitor PXS-5505 Ameliorates Multiple-Organ Fibrosis by Inhibiting Collagen Crosslinks in Rodent Models of Systemic Sclerosis  Journal Articles
• Paraoxonase-1 deficiency in mice predisposes to vascular inflammation, oxidative stress, and thrombogenicity in the absence of hyperlipidemia  Journal Articles
• Pathogenesis of Atherosclerosis  Journal Articles
• Pathophysiological Mechanisms of Stress-Induced Intestina Damage  Journal Articles
• Patient selection may affect gene therapy success. Dominant negative effects observed for ornithine transcarbamylase in mouse and human hepatocytes.  Journal Articles
• Peering into the Crystal Ball: Influenza Pandemics and Vaccine Efficacy  Journal Articles
• Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression  Journal Articles
• Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance  Journal Articles
• Pentastarch in a Balanced Solution Reduces Hepatic Leukocyte Recruitment in Early Sepsis  Journal Articles
• Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression  Journal Articles
• Peptide-based Vaccines in the Treatment of Specific Allergy  Journal Articles
• Peptide-based immunotherapy: a novel strategy for allergic disease  Journal Articles
• Performance of compulsive behavior in rats is not a unitary phenomenon – validation of separate functional components in compulsive checking behavior  Journal Articles
• Perfusion Mapping Using Computed Tomography Allows Accurate Prediction of Cerebral Infarction in Experimental Brain Ischemia  Conferences
• Perindopril treatment prolonged the lifespan of spontaneously hypertensive rats  Journal Articles
• Peripheral nucleotide hydrolysis in rats submitted to a model of electroconvulsive therapy  Journal Articles
• Peritoneal instillation of taurolidine or polihexanide modulates intestinal microcirculation in experimental endotoxemia  Journal Articles
• Persistent gut motor dysfunction in a murine model of T-cell-induced enteropathy  Journal Articles
• Perspectives for the development of animal models of bipolar disorder  Journal Articles
• Perturbations to Homeostasis in Experimental Models Revealed Innate Pathways Driving Food Allergy  Journal Articles
• Photoacoustic imaging of a cyanine dye targeting bacterial infection  Journal Articles
• Pioglitazone increases VEGFR3 expression and promotes activation of M2 macrophages via the peroxisome proliferator‑activated receptor γ  Journal Articles
• Plasminogen II accumulates five times faster than plasminogen I at the site of a balloon de-endothelializing injury in vivo to the rabbit aorta: Comparison with other hemostatic proteins  Journal Articles
• Platelet and fibrinogen turnover at the exposed subendothelium measured over 1 year after a balloon catheter de-endothelializing injury to the rabbit aorta:  Journal Articles
• Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery  Journal Articles
• Polymorphism in the Innate Immune Receptor SIRPα Controls CD47 Binding and Autoimmunity in the Nonobese Diabetic Mouse  Journal Articles
• Porphyria cutanea tarda, or the uroporphyrinogen decarboxylase deficiency diseases  Journal Articles
• Positive end-expiratory pressure above lower inflection point minimizes influx of activated neutrophils into lung*  Journal Articles
• Potential of nintedanib in treatment of progressive fibrosing interstitial lung diseases  Journal Articles
• Pre-surgical neoadjuvant oncolytic virotherapy confers protection against rechallenge in a murine model of breast cancer  Journal Articles
• Preclinical Studies on Mechanisms Underlying the Protective Effects of Propranolol in Traumatic Brain Injury: A Systematic Review  Journal Articles
• Preclinical and Clinical Evidence of Antioxidant Effects of Antidepressant Agents: Implications for the Pathophysiology of Major Depressive Disorder  Journal Articles
• Preclinical development of peptide vaccination combined with oncolytic MG1-E6E7 for HPV-associated cancer  Journal Articles
• Preface to the special issue on computational cognitive neuroscience  Journal Articles
• Preliminary evaluation of oral anticonvulsant treatment in the quinpirole model of bipolar disorder  Journal Articles
• Prevention of peritoneal adhesions using polymeric rheological blends  Journal Articles
• Primary HSV-2 Infection in Early Pregnancy Results in Transplacental Viral Transmission and Dose-Dependent Adverse Pregnancy Outcomes in a Novel Mouse Model  Journal Articles
• Pro-Leu-glycinamide and its peptidomimetic, PAOPA, attenuate haloperidol induced vacuous chewing movements in rat: A model of human tardive dyskinesia  Journal Articles
• Pro-apoptotic and anti-angiogenic actions of 2-methoxyestradiol and docosahexaenoic acid, the biologically derived active compounds from flaxseed diet, in preventing ovarian cancer  Journal Articles
• Probiotics Improve Inflammation-Associated Sickness Behavior by Altering Communication between the Peripheral Immune System and the Brain  Journal Articles
• Profile of betrixaban and its potential in the prevention and treatment of venous thromboembolism  Journal Articles
• Proinflammatory properties of IL-4 in the intestinal microenvironment  Journal Articles
• Prolonged inflammation leads to ongoing damage after spinal cord injury  Journal Articles
• Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota Is Associated With Visceral and Somatic Hypersensitivity  Journal Articles
• Proteasomal Regulation of Cardiac Hypertrophy  Journal Articles
• Protection Against MPTP Treatment by an Analog of Pro-Leu-Gly-NH2 (PLG, MIF-1)  Journal Articles
• Protective effect of pharmacological castration on metabolic perturbations and cardiovascular disease in the hyperglycemic male ApoE−/−:Ins2+/Akita mouse model  Journal Articles
• Protective effects of Xiongshao Capsule (芎芍胶囊) on anti-inflammatory function of high-density lipoprotein in an atherosclerosis rabbit model  Journal Articles
• Protein Kinase C and Oxidative Stress in an Animal Model of Mania  Journal Articles
• Protein arginine methyltransferase expression, localization, and activity during disuse-induced skeletal muscle plasticity  Journal Articles
• Proteolytic bacteria expansion during colitis amplifies inflammation through cleavage of the external domain of PAR2.  Journal Articles
• Proteomic Profiling of Hepatic Endoplasmic Reticulum-associated Proteins in an Animal Model of Insulin Resistance and Metabolic Dyslipidemia  Journal Articles
• Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy  Journal Articles
• Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis  Journal Articles
• Psychosis pathways converge via D2High dopamine receptors  Journal Articles
• Psychostimulant-Induced Behavior as an Animal Model of Obsessive-Compulsive Disorder: An Ethological Approach to the Form of Compulsive Rituals  Journal Articles
• Pulmonary Fibrosis  Journal Articles
• Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells  Journal Articles
• Pulmonary mucosal dendritic cells in T-cell activation: implications for TB therapy  Journal Articles
• Pulmonary structural maturation and pulmonary artery remodeling after reversible fetal ovine tracheal occlusion in diaphragmatic hernia  Conferences
• Purine receptor antagonist modulates serology and affective behaviors in lupus-prone mice: Evidence of autoimmune-induced pain?  Journal Articles
• Purinergic Signalling Mediates Aberrant Excitability of Developing Neuronal Circuits in the Fmr1 Knockout Mouse Model  Journal Articles
• Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells  Journal Articles
• Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus  Journal Articles
• Quantitative MRI in a non‐surgical model of cervical spinal cord injury  Journal Articles
• Quebec platelet disorder  Journal Articles
• Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner  Journal Articles
• Quinpirole and 8-OH-DPAT induce compulsive checking behavior in male rats by acting on different functional parts of an OCD neurocircuit  Journal Articles
• Quinpirole induces compulsive checking behavior in rats: A potential animal model of obsessive-compulsive disorder (OCD).  Journal Articles
• Radiation-induced bystander effects, carcinogenesis and models  Journal Articles
• Rapid development of atherosclerotic lesions in the rabbit carotid artery induced by perivascular manipulation  Journal Articles
• Reactivation of Inflammatory Bowel Disease in a Mouse Model of Depression  Journal Articles
• Rearrangement of the metaphyseal vasculature of the rat growth plate in rickets and rachitic reversal: A model of vascular arrest and angiogenesis renewed  Journal Articles
• Recent Applications of Engineered Animal Antioxidant Deficiency Models in Human Nutrition and Chronic Disease  Journal Articles
• Recent insights into neuromuscular junction biology in Duchenne muscular dystrophy: Impacts, challenges, and opportunities  Journal Articles
• Receptor protein tyrosine phosphatase sigma regulates synapse structure, function and plasticity  Journal Articles
• Reduced Prefrontal Synaptic Connectivity and Disturbed Oscillatory Population Dynamics in the CNTNAP2 Model of Autism  Journal Articles
• Reduced Tissue Levels of Noradrenaline Are Associated with Behavioral Phenotypes of the TgCRND8 Mouse Model of Alzheimer's Disease  Journal Articles
• Reduced expression of synapsin II in a chronic phencyclidine preclinical rat model of schizophrenia  Journal Articles
• Reduced levels of maternal progesterone during pregnancy increase the risk for allergic airway diseases in females only  Journal Articles
• Reduced metabotropic glutamate receptor 5 in the Flinders Sensitive Line of rats, an animal model of depression: An autoradiographic study  Journal Articles
• Reduced tissue macrophage population in the lung by anticancer agent cyclophosphamide: restoration by local granulocyte macrophage–colony-stimulating factor gene transfer  Journal Articles
• Reduction of GAG storage in MPS II mouse model following implantation of encapsulated recombinant myoblasts  Journal Articles
• Reduction of thrombus size in murine models of thrombosis following administration of recombinant α1-proteinase inhibitor mutant proteins  Journal Articles
• Regional brain volumes changes in adult male FMR1-KO mouse on the FVB strain  Journal Articles
• Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3  Journal Articles
• Regulation of signal transducer, gp130 and the lif receptor in acute inflammation in vivo  Journal Articles
• Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells  Journal Articles
• Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice  Journal Articles
• Relationship between the anticoagulant and antithrombotic effects of heparin in experimental venous thrombosis  Journal Articles
• Relationships among tumor burden, tumor size, and the changing concentrations of fibrin degradation products and fibrinolytic factors in the pleural effusions of rabbits with VX2 lung tumors  Journal Articles
• Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis  Journal Articles
• Repetitive invasive lung function maneuvers do not accentuate experimental fibrosis in mice  Journal Articles
• Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid  Journal Articles
• Reproductive and developmental effects of phthalate diesters in males  Journal Articles
• Resistance training minimizes catabolic effects induced by sleep deprivation in rats  Journal Articles
• Response of the rat intestinal microcirculation to experimental endotoxemia is attenuated by ampicillin but not by its derivative KKP723.  Journal Articles
• Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis  Journal Articles
• Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene  Journal Articles
• Review: Behaviour of MRL Mice: An Animal Model of Disturbed Behaviour in Systemic Autoimmune Disease  Journal Articles
• Robust effects of genetic background on responses to subarachnoid hemorrhage in mice.  Journal Articles
• Role for NLRP3 Inflammasome–mediated, IL-1β–Dependent Responses in Severe, Steroid-Resistant Asthma  Journal Articles
• Role of Estrogen in Type 1 and Type 2 Diabetes Mellitus: A Review of Clinical and Preclinical Data  Journal Articles
• Role of Macrophage Migration Inhibitory Factor in Granulomatosis With Polyangiitis  Conferences
• Role of P2X7 Receptor in an Animal Model of Mania Induced by D-Amphetamine  Journal Articles
• Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study  Journal Articles
• Role of dopamine systems in obsessive-compulsive disorder (OCD): implications from a novel psychostimulant-induced animal model.  Journal Articles
• Role of environmental factors and epigenetics in autism spectrum disorders  Chapters
• Role of the COX2-PGE₂ axis in S. pneumoniae-induced exacerbation of experimental fibrosis  Journal Articles
• Ron receptor tyrosine kinase-dependent hepatic neutrophil recruitment and survival benefit in a murine model of bacterial peritonitis  Journal Articles
• Rosiglitazone improves pancreatic mitochondrial function in an animal model of dysglycemia: role of the insulin-like growth factor axis  Journal Articles
• Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering  Journal Articles
• SECOND HIT POST BURN INCREASED PROXIMAL GUT MUCOSA EPITHELIAL CELLS DAMAGE  Journal Articles
• SMAD3-dependent and -independent pathways in glomerular injury associated with experimental glomerulonephritis  Journal Articles
• SR-BI in Bone Marrow Derived Cells Protects Mice from Diet Induced Coronary Artery Atherosclerosis and Myocardial Infarction  Journal Articles
• Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice  Journal Articles
• Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine  Journal Articles
• Salsalate, but not metformin or canagliflozin, slows kidney cyst growth in an adult-onset mouse model of polycystic kidney disease  Journal Articles
• Se(XY) matters: the importance of incorporating sex in microphysiological models  Journal Articles
• Secondary Acylation of Klebsiella pneumoniae Lipopolysaccharide Contributes to Sensitivity to Antibacterial Peptides  Journal Articles
• Secreted PLA2 group X orchestrates innate and adaptive immune responses to inhaled allergen  Journal Articles
• Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits  Journal Articles
• Sensory Nerve Cross-Anastomosis and Electrical Muscle Stimulation Synergistically Enhance Functional Recovery of Chronically Denervated Muscle  Journal Articles
• Sensory Protection of Rat Muscle Spindles following Peripheral Nerve Injury and Reinnervation  Journal Articles
• Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation  Journal Articles
• Separate mechanisms for development and performance of compulsive checking in the quinpirole sensitization rat model of obsessive-compulsive disorder (OCD)  Journal Articles
• Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts  Journal Articles
• Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines  Journal Articles
• Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice  Journal Articles
• Sex-Specific Differences in an ApoE−/−:Ins2+/Akita Mouse Model of Accelerated Atherosclerosis  Journal Articles
• Sex-based analysis of treatment responses in animal models of sepsis: a preclinical systematic review protocol  Journal Articles
• Shedding a new light on Huntington’s disease: how blood can both propagate and ameliorate disease pathology  Journal Articles
• Short-Course Therapy of Gemifloxacin Effective Against Pneumococcal Pneumonia in Mice  Journal Articles
• Signaling at the Fetomaternal Interface  Journal Articles
• Simple model systems reveal conserved mechanisms of Alzheimer’s disease and related tauopathies  Journal Articles
• Single-Dose Mucosal Immunotherapy With Chimpanzee Adenovirus-Based Vaccine Accelerates Tuberculosis Disease Control and Limits Its Rebound After Antibiotic Cessation  Journal Articles
• Singlet Oxygen Luminescence Dosimetry (SOLD) for Photodynamic Therapy: Current Status, Challenges and Future Prospects  Journal Articles
• Skeletal Adaptations to Alterations in Weight-Bearing Activity  Journal Articles
• Skeletal muscle mitochondrial and autophagic dysregulation are modifiable in spinal muscular atrophy  Journal Articles
• Sleep Architecture in a Canine Model of Obstructive Sleep Apnea  Journal Articles
• Small Molecule Antagonists of the Wnt/Beta-Catenin Signaling Pathway Target Breast Tumor-Initiating Cells in a Her2/Neu Mouse Model of Breast Cancer  Journal Articles
• Small animal models of thermal injury  Chapters
• Small rodent models of atherosclerosis  Journal Articles
• Small-Molecule Allosteric Triggers of Clostridium difficile Toxin B Auto-proteolysis as a Therapeutic Strategy  Journal Articles
• Social interaction modulates the intensity of compulsive checking in a rat model of obsessive-compulsive disorder (OCD)  Journal Articles
• Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract  Journal Articles
• Sperm Chromatin Structure Is Altered in Cynomolgus Monkeys With Environmentally Relevant Blood Lead Levels  Journal Articles
• Spermidine metabolism regulates leukemia stem and progenitor cell function through KAT7 expression in patient-derived mouse models.  Journal Articles
• Sphingosine-1-phosphate receptor 3 regulates the transendothelial transport of high-density lipoproteins and low-density lipoproteins in opposite ways.  Journal Articles
• Spinal cord injury models in non human primates: Are lesions created by sharp instruments relevant to human injuries?  Journal Articles
• Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase  Journal Articles
• Spotlight on animal models of acute traumatic coagulopathy: an update  Journal Articles
• Squalamine Restores the Function of the Enteric Nervous System in Mouse Models of Parkinson’s Disease  Journal Articles
• SseL Is a Salmonella -Specific Translocated Effector Integrated into the SsrB-Controlled Salmonella Pathogenicity Island 2 Type III Secretion System  Journal Articles
• Starvation‐Induced Proximal Gut Mucosal Atrophy Diminished With Aging  Journal Articles
• Stereologic Analysis of Tibial-Plateau Cartilage and Femoral Cancellous Bone in Guinea Pigs With Spontaneous Osteoarthritis  Journal Articles
• Strain- and Species-Level Variation in the Microbiome of Diabetic Wounds Is Associated with Clinical Outcomes and Therapeutic Efficacy  Journal Articles
• Strain-specific differences in cell proliferation and differentiation in the dentate gyrus of C57BL/6N and C3H/HeN mice fed a high fat diet  Journal Articles
• Streptococcus pneumoniae Colonization Is Required To Alter the Nasal Microbiota in Cigarette Smoke-Exposed Mice  Journal Articles
• Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin  Journal Articles
• Stress‐Triggered Abortion: Inhibition of Protective Suppression and Promotion of Tumor Necrosis Factor‐α (TNF‐α) Release as a Mechanism Triggering Resorptions in Mice  Journal Articles
• Stretch-induced Activation of Transforming Growth Factor-β₁ in Pulmonary Fibrosis  Journal Articles
• Stromal β-catenin overexpression contributes to the pathogenesis of renal dysplasia  Journal Articles
• Structure–Function Relationships of Human Milk Oligosaccharides on the Intestinal Epithelial Transcriptome in Caco‐2 Cells and a Murine Model of Necrotizing Enterocolitis  Journal Articles
• Suppression of NK and CD8+ T cells reduces astrogliosis but accelerates cerebellar dysfunction and shortens life span in a mouse model of Sandhoff disease  Journal Articles
• Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis  Journal Articles
• Sustained and therapeutic levels of human factor IX in hemophilia B mice implanted with microcapsules: key role of encapsulated cells  Journal Articles
• Synapsin II knockout mice show sensorimotor gating and behavioural abnormalities similar to those in the phencyclidine-induced preclinical animal model of schizophrenia  Journal Articles
• Syndecan-1 (CD138) deficiency increases Staphylococcus aureus infection but has no effect on pathology in a mouse model of peritoneal dialysis  Journal Articles
• Synergistic effects of diet and exercise on hippocampal function in chronically stressed mice  Journal Articles
• Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis*  Journal Articles
• Systemic FasL and TRAIL Neutralisation Reduce Leishmaniasis Induced Skin Ulceration  Journal Articles
• Systemic aspects of chronic rhinosinusitis  Journal Articles
• T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice  Journal Articles
• T-cell-mediated inflammation does not contribute to the maintenance of airway dysfunction in mice  Journal Articles
• T-lymphocyte modulation of intestinal muscle function in the Trichinella-infected rat  Journal Articles
• TAOK2 rescues autism-linked developmental deficits in a 16p11.2 microdeletion mouse model  Journal Articles
• TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells  Journal Articles
• TGF-β and Smad3 Signaling Link Inflammation to Chronic Fibrogenesis  Journal Articles
• TGF-β1 gene transfer to the mouse colon leads to intestinal fibrosis  Journal Articles
• TGFβ Programs Central Memory Differentiation inEx Vivo–Stimulated Human T Cells  Journal Articles
• THE EFFECTS OF DNASE I AND LOW-MOLECULAR-WEIGHT HEPARIN IN A MURINE MODEL OF POLYMICROBIAL ABDOMINAL SEPSIS  Journal Articles
• TIM-4 Expressed by Mucosal Dendritic Cells Plays a Critical Role in Food Antigen–Specific Th2 Differentiation and Intestinal Allergy  Journal Articles
• TNF is a critical cytokine in age-related dry eye disease  Journal Articles
• TRIM33 prevents pulmonary fibrosis by impairing TGF-β1 signalling  Journal Articles
• Tamoxifen effects on respiratory chain complexes and creatine kinase activities in an animal model of mania  Journal Articles
• Targeted Inhibition of Serotonin Type 7 (5-HT7) Receptor Function Modulates Immune Responses and Reduces the Severity of Intestinal Inflammation  Journal Articles
• Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function  Journal Articles
• Targeting C3a/C5a receptors inhibits human mesangial cell proliferation and alleviates immunoglobulin A nephropathy in mice  Journal Articles
• Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment.  Journal Articles
• Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model  Journal Articles
• Targeting cellular energy production in neurological disorders  Journal Articles
• Targeting cellular energy production in neurological disorders.  Journal Articles
• Taste responsiveness and diet preference in autoimmune MRL mice  Journal Articles
• Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease  Journal Articles
• Taxol Involution of Collagen-Induced Arthritis: Ultrastructural Correlation with the Inhibition of Synovitis and Neovascularization  Journal Articles
• Temporal and spectral differences in the ultrasonic vocalizations of fragile X knock out mice during postnatal development  Journal Articles
• Temporal–Spatial Analysis of the Immune Response in a Murine Model of Ovalbumin-Induced Airways Inflammation  Journal Articles
• Testicular atrophy in the spontaneously diabetic BB Wistar rat.  Journal Articles
• The yjeQ Gene Is Required for Virulence of Staphylococcus aureus  Journal Articles
• The Absence or Overexpression of IL-15 Drastically Alters Breast Cancer Metastasis via Effects on NK Cells, CD4 T Cells, and Macrophages  Journal Articles
• The Application of Humanized Mouse Models for the Study of Human Exclusive Viruses  Journal Articles
• The Commensal Bacterium Faecalibacterium prausnitzii Is Protective in DNBS-induced Chronic Moderate and Severe Colitis Models  Journal Articles
• The Cystic Fibrosis Gene: A Molecular Genetic Perspective  Journal Articles
• The Effect of Thrombin Inhibitors on Tissue Plasminogen Activator Induced Thrombolysis in a Rat Model  Journal Articles
• The Effect of Tracheal Occlusion on Lung Branching in the Rat Nitrofen CDH Model  Journal Articles
• The Effects of Diet on Occlusive Coronary Artery Atherosclerosis and Myocardial Infarction in Scavenger Receptor Class B, Type 1/Low-Density Lipoprotein Receptor Double Knockout Mice  Journal Articles
• The FMS-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis  Journal Articles
• The Importance of Obtaining Conjugate Views on Renographic Evaluation of Large Hydronephrotic Kidneys: An In Vitro and Ex Vivo Analysis  Journal Articles
• The Inflammatory Hypothesis  Journal Articles
• The Isosteroid Alkaloid Imperialine from Bulbs of Fritillaria cirrhosa Mitigates Pulmonary Functional and Structural Impairment and Suppresses Inflammatory Response in a COPD-Like Rat Model.  Journal Articles
• The MRL Model: A Valuable Tool in Studies of Autoimmunity-Brain Interactions  Journal Articles
• The MRL Model: An Invaluable Tool in Studies of Autoimmunity–Brain Interactions  Journal Articles
• The NLRP3 inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice  Journal Articles
• The Pathogenesis of Neurotrauma Indicates Targets for Neuroprotective Therapies  Journal Articles
• The Pathophysiology of the Peritoneal Membrane  Journal Articles
• The Peripheral Nerve Allograft  Journal Articles
• The Role of Astrogliosis in Formation of the Syrinx in Spinal Cord Injury  Journal Articles
• The Role of Serotonin during Skin Healing in Post-Thermal Injury  Journal Articles
• The Role of Serotonin in Breast Cancer Stem Cells  Journal Articles
• The SseC translocon component in Salmonella enterica serovar Typhimurium is chaperoned by SscA  Journal Articles
• The TGFβ-ERK pathway contributes to Notch3 upregulation in the renal tubular epithelial cells of patients with obstructive nephropathy  Journal Articles
• The Vagus Nerve: A Tonic Inhibitory Influence Associated With Inflammatory Bowel Disease in a Murine Model  Journal Articles
• The WAGxDA rat: An animal model of cholinergic supersensitivity  Journal Articles
• The aetiology, consequences and prevention of barotrauma: a critical review of the literature  Journal Articles
• The attenuated virulence of a Burkholderia cenocepacia paaABCDE mutant is due to inhibition of quorum sensing by release of phenylacetic acid  Journal Articles
• The benefit of intraperitoneal chemotherapy for the treatment of colorectal carcinomatosis  Journal Articles
• The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?  Journal Articles
• The clinical antiprotozoal drug halofuginone promotes weight loss by elevating GDF15 and FGF21.  Journal Articles
• The complement factor C5a receptor is upregulated in NFL−/− mouse motor neurons  Journal Articles
• The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo  Journal Articles
• The effect of anatomic location on porcine models of burn injury and wound healing  Journal Articles
• The effect of hepatocyte growth factor on gut mucosal apoptosis and proliferation, and cellular mediators after severe trauma  Journal Articles
• The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice  Journal Articles
• The effects of inhaled house dust mite on airway barrier function and sensitivity to inhaled methacholine in mice  Journal Articles
• The impact of dietary fermentable carbohydrates on a postinflammatory model of irritable bowel syndrome  Journal Articles
• The impact of early life gut colonization on metabolic and obesogenic outcomes: what have animal models shown us?  Journal Articles
• The impact of perfluoroalkyl substances on pregnancy, birth outcomes, and offspring development: a review of data from mouse models  Journal Articles
• The impact of the ovarian microenvironment on the anti-tumor effect of SPARC on ovarian cancer¹This article is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal’s usual peer review process.  Journal Articles
• The importance of being a regulatory T cell in pregnancy  Journal Articles
• The importance of interventional timing in the bleomycin model of pulmonary fibrosis  Journal Articles
• The influence of P-glycoprotein expression and its inhibitors on the distribution of doxorubicin in breast tumors  Journal Articles
• The link between environmental toxicant exposure and endometriosis  Journal Articles
• The many faces of airway inflammation. Asthma and chronic obstructive pulmonary disease. Asthma Research Group.  Journal Articles
• The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies  Journal Articles
• The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms  Journal Articles
• The polymicrobial nature of airway infections in cystic fibrosis: Cangene Gold Medal LectureThis article is based on a presentation by Dr. Christopher Sibley at the 60th Annual Meeting of the Canadian Society of Microbiologists in Hamilton, Ontario, on 15 June 2010. Dr. Sibley was the recipient of the 2010 Cangene Gold Medal as the Canadian Graduate Student Microbiologist of the Year, an annual award sponsored by Cangene Corporation intended to recognize excellence in graduate research.  Journal Articles
• The protective effect of the vagus nerve in a murine model of chronic relapsing colitis  Journal Articles
• The putative role of the intestinal microbiota in the irritable bowel syndrome  Journal Articles
• The reproductive cycle is a pathogenic determinant during gonococcal pelvic inflammatory disease in mice  Journal Articles
• The role of ICP0-Null HSV-1 and interferon signaling defects in the effective treatment of breast adenocarcinoma  Journal Articles
• The role of cannabis in treating anxiety  Journal Articles
• The role of hippocampus in the pathophysiology of bipolar disorder  Journal Articles
• The slow-release adiponectin analog ALY688-SR modifies early-stage disease development in the D2.mdx mouse model of Duchenne muscular dystrophy  Journal Articles
• The small heat‐shock protein αB‐crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis  Journal Articles
• The thrombogenicity of C1 esterase inhibitor (human): Review of the evidence  Journal Articles
• The use and misuse of animal analog models of human pregnancy disorders  Journal Articles
• The valproic acid-induced rodent model of autism  Journal Articles
• The water maze paradigm in experimental studies of chronic cognitive disorders: Theory, protocols, analysis, and inference  Journal Articles
• The worm turns for antimicrobial discovery  Journal Articles
• Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease.  Journal Articles
• Therapeutic effects of the endothelin receptor antagonist Ro 48-5695 in the TNBS/DNBS rat model of colitis  Journal Articles
• Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma  Journal Articles
• Three-dimensional computed tomography imaging in an animal model of emphysema  Journal Articles
• Thrombin-activatable fibrinolysis inhibitor and sex modulate thrombus stability and pulmonary embolism burden in a murine model  Journal Articles
• Thrombin-activatable fibrinolysis inhibitor is activated in vivo in a baboon model of Escherichia coli induced sepsis  Journal Articles
• Thrombolysis with a Combination of Small Doses of Streptokinase and Full Doses of Heparin  Journal Articles
• Thrombus stability explains the factor V Leiden paradox: a mouse model  Journal Articles
• Time course and nature of brain atrophy in the MRL mouse model of central nervous system lupus  Journal Articles
• Tissue Factor and Thrombosis Models  Journal Articles
• Toll-like receptors 2 and 7 mediate coagulation activation and coagulopathy in murine sepsis.  Journal Articles
• Toll‐Like Receptor (TLR)–3, but Not TLR4, Agonist Protects against Genital Herpes Infection in the Absence of Inflammation Seen with CpG DNA  Journal Articles
• Tracheoscopic endotracheal occlusion in the ovine model: Technique and pulmonary effects  Conferences
• Tracking gastrointestinal transit of solids in aged rats as pharmacological models of chronic dysmotility  Journal Articles
• Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73  Journal Articles
• Transfer of the Active Form of Transforming Growth Factor-β1 Gene to Newborn Rat Lung Induces Changes Consistent with Bronchopulmonary Dysplasia  Journal Articles
• Transgenic expression of neuronal dystonin isoform 2 partially rescues the disease phenotype of the dystonia musculorum mouse model of hereditary sensory autonomic neuropathy VI.  Journal Articles
• Transgenic mice expressing the βAPP695SWE mutation: effects on exploratory activity, anxiety, and motor coordination  Journal Articles
• Transient Corticosteroid Treatment Permanently Amplifies the Th2 Response in a Murine Model of Asthma  Journal Articles
• Transient Overexpression of TGF-β1 Induces Epithelial Mesenchymal Transition in the Rodent Peritoneum  Journal Articles
• Transient caloric restriction in early adulthood hastens disease endpoint in male, but not female, Cu/Zn‐SOD mutant G93A mice  Journal Articles
• Transient middle cerebral artery occlusion induces microglial priming in the lumbar spinal cord: a novel model of neuroinflammation  Journal Articles
• Transplantation of Monocytes: A Novel Strategy forIn VivoAugmentation of Collateral Vessel Growth  Journal Articles
• Transplants of neurosphere cell suspensions from aged mice are functional in the mouse model of Parkinson's  Journal Articles
• Treating Viral Exacerbations of Chronic Obstructive Pulmonary Disease: Insights from a Mouse Model of Cigarette Smoke and H1N1 Influenza Infection  Journal Articles
• Treatment of Prion Disease with Heterologous Prion Proteins  Journal Articles
• Treatment of idiopathic pulmonary fibrosis: an update on emerging drugs in phase II & III clinical trials  Journal Articles
• Treatment with apolipoprotein A1 protects mice against doxorubicin-induced cardiotoxicity in a scavenger receptor class B, type I-dependent manner  Journal Articles
• Treatment with atorvastatin ameliorates hepatic very[ndash ]low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: Evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity  Journal Articles
• Tregs and allergic disease  Journal Articles
• Trends and recommendations in studies of mouse airway function  Journal Articles
• Trophic and proliferative effects of Shh on motor neurons in embryonic spinal cord culture from wildtype and G93A SOD1 mice  Journal Articles
• Trophoblast Invasion and Blood Vessel Remodeling Are Altered in a Rat Model of Lifelong Maternal Obesity  Journal Articles
• Truncating Mutations in UBAP1 Cause Hereditary Spastic Paraplegia  Journal Articles
• Type I Insulin-like Growth Factor Receptor Induces Pulmonary Tumorigenesis  Journal Articles
• Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells  Journal Articles
• USP22 mediates the multidrug resistance of hepatocellular carcinoma via the SIRT1/AKT/MRP1 signaling pathway  Journal Articles
• Ultrastructural dynamics of experimental atherosclerosis.  Journal Articles
• Ultrastructural pathology of the myocardium.  Journal Articles
• Unconventional screening approaches for antibiotic discovery  Journal Articles
• Understanding the Role of DISC1 in Psychiatric Disease and during Normal Development  Journal Articles
• Unique microbial-derived volatile organic compounds in portal venous circulation in murine non-alcoholic fatty liver disease  Journal Articles
• Untapped "-omics": the microbial metagenome, estrobolome, and their influence on the development of breast cancer and response to treatment.  Journal Articles
• Untitled  Journal Articles
• Use of Antenatal Steroids to Counteract the Negative Effects of Tracheal Occlusion in the Fetal Lamb Model  Journal Articles
• Use of a murine xenograft model for canine transmissible venereal tumor  Journal Articles
• Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation  Journal Articles
• VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats  Journal Articles
• Vagus nerve integrity and experimental colitis  Journal Articles
• Vanadate, an inhibitor of stromelysin and collagenase expression, suppresses collagen induced arthritis.  Journal Articles
• Varicose Remodeling of Veins Is Suppressed by 3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Inhibitors  Journal Articles
• Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality  Journal Articles
• Ventilatory and Arousal Responses to Hypoxia and Hypercapnia in a Canine Model of Obstructive Sleep Apnea  Journal Articles
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• WISH-PC2: a unique xenograft model of human prostatic small cell carcinoma.  Journal Articles
• WNT signaling is required for peritoneal membrane angiogenesis  Journal Articles
• What’s New in Shock, August 2014?  Journal Articles
• Wnt activation as a therapeutic strategy in medulloblastoma  Journal Articles
• Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal muscle fibers  Journal Articles
• Zebrafish models of major depressive disorders  Journal Articles
• [18F]Fluorodeoxyglucose Uptake in Neonatal Acute Lung Injury Measured by Positron Emission Tomography1  Journal Articles
• cAMP response element–binding protein is expressed at high levels in human ovarian adenocarcinoma and regulates ovarian tumor cell proliferation  Journal Articles
• xCT knockdown in human breast cancer cells delays onset of cancer-induced bone pain  Journal Articles
• β-Adrenergic blockade attenuates adverse adipose tissue responses after burn.  Journal Articles
• β-Catenin Causes Renal Dysplasia via Upregulation of Tgfβ2 and Dkk1  Journal Articles
• β-Catenin/CBP–Dependent Signaling Regulates TGF-β–Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells  Journal Articles
• β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer  Journal Articles