Journal article
Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania
Abstract
Progression of bipolar disorder (BD) has been associated with cognitive impairment and changes in neuroplasticity, including a decrease in serum brain-derived neurotrophic factor (BDNF). However, no study could examine BDNF levels directly in different brain regions after repeated mood episodes to date. The proposed animal model was designed to mimic several manic episodes and evaluate whether the performance in memory tasks and BDNF levels in …
Authors
Fries GR; Valvassori SS; Bock H; Stertz L; da Silva Magalhães PV; Mariot E; Varela RB; Kauer-Sant’Anna M; Quevedo J; Kapczinski F
Journal
Journal of Psychiatric Research, Vol. 68, , pp. 329–336
Publisher
Elsevier
Publication Date
September 2015
DOI
10.1016/j.jpsychires.2015.05.006
ISSN
0022-3956