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The Pathogenesis of Neurotrauma Indicates Targets...
Journal article

The Pathogenesis of Neurotrauma Indicates Targets for Neuroprotective Therapies

Abstract

The spinal cord injury (SCI) initiates an extraordinarily protracted disease with 3 phases; acute, inflammatory, and resolution that are restricted to the cavity of injury (COI) or arachnoiditis by a unique CNS reaction against the severity of destructive inflammation. While the severity of inflammation involving the white matter is fueled by a potently immunogenic activity of damaged myelin, its sequestration in the COI and its continuity with …

Authors

Kwiecien JM

Journal

Current Neuropharmacology, Vol. 19, No. 8, pp. 1191–1201

Publisher

Bentham Science Publishers

Publication Date

2021

DOI

10.2174/1570159x19666210125153308

ISSN

1570-159X