Journal article
Syndecan-1 (CD138) deficiency increases Staphylococcus aureus infection but has no effect on pathology in a mouse model of peritoneal dialysis
Abstract
BackgroundTechnique failure in peritoneal dialysis (PD) due to fibrosis and angiogenesis is complicated by peritonitis. Staphylococcus aureus infection is one of the most common causes of peritonitis in PD. The heparan sulfate proteoglycan, syndecan-1 (CD138), was reported to regulate fibrosis, angiogenesis, inflammation and S. aureus infection. The objectives of this study were to examine the effects of syndecan-1 on S. aureus infection and …
Authors
Kowalewska PM; Nguyen UT; Burrows LL; Fox-Robichaud AE
Journal
Journal of Biomedical Science, Vol. 23, No. 1,
Publisher
Springer Nature
Publication Date
December 2016
DOI
10.1186/s12929-016-0232-9
ISSN
1021-7770