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The MRL Model: A Valuable Tool in Studies of...
Journal article

The MRL Model: A Valuable Tool in Studies of Autoimmunity-Brain Interactions

Abstract

The link between systemic autoimmunity, brain pathology, and aberrant behavior is still a largely unexplored field of biomedical science. Accumulating evidence points to causal relationships between immune factors, neurodegeneration, and neuropsychiatric manifestations. By documenting autoimmunity-associated neuronal degeneration and cytotoxicity of the cerebrospinal fluid from disease-affected subjects, the murine MRL model had shown high …

Authors

Šakić B

Journal

Methods in Molecular Biology, Vol. 1781, , pp. 259–285

Publisher

Springer Nature

Publication Date

2018

DOI

10.1007/978-1-4939-7828-1_14

ISSN

1064-3745