Journal article
Mechanisms of microthrombi formation after experimental subarachnoid hemorrhage
Abstract
Microcirculatory dysfunction may contribute to delayed cerebral ischemia after subarachnoid hemorrhage (SAH). Using a prechiasmatic injection model, this study investigated ultrastructural changes in microvessels in brain parenchyma to determine the nature of the microthromboemboli, the involvement of nitric oxide (NO) and P-selectin in their formation, and relationship to brain injury after SAH. Brains were examined by electron microscopy (EM) …
Authors
Sabri M; Ai J; Lakovic K; D’abbondanza J; Ilodigwe D; Macdonald RL
Journal
Neuroscience, Vol. 224, , pp. 26–37
Publisher
Elsevier
Publication Date
11 2012
DOI
10.1016/j.neuroscience.2012.08.002
ISSN
0306-4522