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Alteration of perivascular adipose tissue function...
Journal article

Alteration of perivascular adipose tissue function in angiotensinII-induced hypertension

Abstract

We studied the role of perivascular adipose tissue (PVAT) in the control of vascular function in an in vivo experimental model of hypertension produced by angiotensin II infusion by osmotic minipump in adult male Wistar rats. Two weeks after infusion with angiotensin II, blood pressure in treated rats was significantly elevated but heart rate was reduced compared with control rats infused with physiological saline. Contraction of aorta from the …

Authors

Lee RMKW; Ding L; Lu C; Su L-Y; Gao Y-J

Journal

Canadian Journal of Physiology and Pharmacology, Vol. 87, No. 11, pp. 944–953

Publisher

Canadian Science Publishing

Publication Date

November 2009

DOI

10.1139/y09-088

ISSN

0008-4212