Journal article
Effects of dopexamine on the intestinal microvascular blood flow and leucocyte activation in a sepsis model in rats
Abstract
IntroductionDopexamine may be a therapeutic option to improve hepatosplanchnic perfusion in sepsis. To investigate this possibility, we administered dopexamine in an experimental sepsis model in rats.MethodsThis prospective, randomized, controlled laboratory study was conducted in 42 Wistar rats. The animals were divided into three groups. Group 1 served as the control group (CON group). The animals in both groups 2 (LPS group) and 3 (DPX …
Authors
Birnbaum J; Klotz E; Spies CD; Lorenz B; Stuebs P; Hein OV; Gründling M; Pavlovic D; Usichenko T; Wendt M
Journal
Critical Care, Vol. 10, No. 4,
Publisher
Springer Nature
Publication Date
2006
DOI
10.1186/cc5011
ISSN
1364-8535