Journal article
Ketamine alters behavior and decreases BDNF levels in the rat brain as a function of time after drug administration
Abstract
OBJECTIVE: To evaluate behavioral changes and brain-derived neurotrophic factor (BDNF) levels in rats subjected to ketamine administration (25 mg/kg) for 7 days.
METHOD: Behavioral evaluation was undertaken at 1 and 6 hours after the last injection.
Authors
Fraga DB; Réus GZ; Abelaira HM; De Luca RD; Canever L; Pfaffenseller B; Colpo GD; Kapczinski F; Quevedo J; Zugno AI
Journal
Brazilian Journal of Psychiatry, Vol. 35, No. 3, pp. 262–266
Publisher
EDITORA SCIENTIFIC
Publication Date
September 2013
DOI
10.1590/1516-4446-2012-0858
ISSN
1516-4446