Journal article
Differences in electrophysiological properties of functionally identified nociceptive sensory neurons in an animal model of cancer-induced bone pain
Abstract
BACKGROUND: Bone cancer pain is often severe, yet little is known about mechanisms generating this type of chronic pain. While previous studies have identified functional alterations in peripheral sensory neurons that correlate with bone tumours, none has provided direct evidence correlating behavioural nociceptive responses with properties of sensory neurons in an intact bone cancer model.
RESULTS: In a rat model of prostate cancer-induced …
Authors
Zhu YF; Ungard R; Seidlitz E; Zacal N; Huizinga J; Henry JL; Singh G
Journal
Molecular Pain, Vol. 12, ,
Publisher
SAGE Publications
Publication Date
January 1, 2016
DOI
10.1177/1744806916628778
ISSN
1744-8069