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WNT signaling is required for peritoneal membrane...
Journal article

WNT signaling is required for peritoneal membrane angiogenesis

Abstract

The wingless-type mouse mammary tumor virus integration site family (WNT) signaling pathway is involved in wound healing and fibrosis. We evaluated the WNT signaling pathway in peritoneal membrane injury. We assessed WNT1 protein expression in the peritoneal effluents of 54 stable peritoneal dialysis (PD) patients and WNT-related gene expression in ex vivo mesothelial cell cultures from 21 PD patients. In a transforming growth factor-β …

Authors

Padwal M; Cheng G; Liu L; Boivin F; Gangji AS; Brimble KS; Bridgewater D; Margetts PJ

Journal

American Journal of Physiology. Renal physiology, Vol. 314, No. 6, pp. f1036–f1045

Publisher

American Physiological Society

Publication Date

June 1, 2018

DOI

10.1152/ajprenal.00497.2017

ISSN

0363-6127