Journal article
Tissue Factor and Thrombosis Models
Abstract
Mouse models of thrombosis have extended our understanding of the role of tissue factor (TF) in thrombogenesis. Because tissue factor deficiency is embryonic lethal in mice, inventive genetic models are required to probe the role of TF in thrombosis. TF is expressed by different cell types, including vascular smooth muscle cells, cardiomyocytes, fibroblasts, and monocytes. Platelets and endothelial cells also express TF under certain …
Authors
Kretz CA; Vaezzadeh N; Gross PL
Journal
Arteriosclerosis Thrombosis and Vascular Biology, Vol. 30, No. 5, pp. 900–908
Publisher
Wolters Kluwer
Publication Date
May 2010
DOI
10.1161/atvbaha.108.177477
ISSN
1079-5642