Journal article
Haemopoietic mechanisms in murine allergic upper and lower airway inflammation
Abstract
Eosinophil recruitment to the airways, including involvement of haemopoietic eosinophil-basophil progenitors (Eo/B-CFU), is primarily regulated by interleukin-5 (IL-5) and eotaxin. In this study, we investigated the haemopoietic mechanisms in upper and lower airway eosinophilic inflammation. Ovalbumin (OVA) sensitized and challenged BALB/c mice were used to establish isolated upper (UAC), isolated lower (LAC), or combined upper and lower airway …
Authors
Li J; Saito H; Crawford L; Inman MD; Cyr MM; Denburg JA
Journal
Immunology, Vol. 114, No. 3, pp. 386–396
Publisher
Wiley
Publication Date
March 2005
DOI
10.1111/j.1365-2567.2005.02109.x
ISSN
0019-2805