Journal article
Effects of the serotonergic agonist mCPP on male rats in the quinpirole sensitization model of obsessive–compulsive disorder (OCD)
Abstract
RationaleThe serotonergic agonist, meta-chlorophenylpiperazine (mCPP), produces inconsistent effects on obsessive–compulsive disorder (OCD) symptoms, perhaps because clinical studies have not utilized a homogenous OCD subgroup of patients.ObjectivesThis study aimed to evaluate mCPP effects on functional components of compulsive checking, using the quinpirole sensitization rat model of OCD.MethodsIn study 1, the effects of mCPP were evaluated in …
Authors
Tucci MC; Dvorkin-Gheva A; Graham D; Amodeo S; Cheon P; Kirk A; Peel J; Taji L; Szechtman H
Journal
Psychopharmacology, Vol. 227, No. 2, pp. 277–285
Publisher
Springer Nature
Publication Date
May 2013
DOI
10.1007/s00213-013-2976-1
ISSN
0033-3158