Journal article
Neuronal Nitric Oxide Synthase Is a Novel Biomarker for the Interstitial Cells of Cajal in Stress-Induced Diarrhea-Dominant Irritable Bowel Syndrome
Abstract
BackgroundIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder involving changes in normal bowel movements. The pathophysiology of IBS is not clearly understood owing to the lack of identifiable pathological abnormalities and reliable biomarkers.AimThe aim of this study was to discover the novel and reliable biomarker for IBS.MethodIn this study, neonatal maternal separation (NMS) stress model was used for the IBS mouse …
Authors
Jang DE; Bae JH; Chang YJ; Lee YH; Nam KT; Kim IY; Seong JK; Lee YC; Yeom SC
Journal
Digestive Diseases and Sciences, Vol. 63, No. 3, pp. 619–627
Publisher
Springer Nature
Publication Date
3 2018
DOI
10.1007/s10620-018-4933-7
ISSN
0163-2116