Journal article
Anti‐ulcerogenic properties of endothelin receptor antagonists in the rat
Abstract
BACKGROUND: Endothelins have been implicated in gastric mucosal damage in a variety of animal models. Exogenous ET-1 and ET-3 are causally associated with experimental gastric ulcers. Furthermore, clinical reports also show elevated plasma and gastric mucosal endothelin-1 levels in patients suffering from peptic ulcers.
AIM: To study the possibility that endothelin receptor antagonists may have beneficial effects and prevent the development of …
Authors
PADOL; HUANG; HUNT
Journal
Alimentary Pharmacology & Therapeutics, Vol. 13, No. 4, pp. 537–544
Publisher
Wiley
Publication Date
April 1999
DOI
10.1046/j.1365-2036.1999.00503.x
ISSN
0269-2813