Journal article
PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R)
Abstract
While neuroinflammation is an evolving concept and the cells involved and their functions are being defined, microglia are understood to be a key cellular mediator of brain injury and repair. The ability to measure microglial activity specifically and noninvasively would be a boon to the study of neuroinflammation, which is involved in a wide variety of neuropsychiatric disorders including traumatic brain injury, demyelinating disease, …
Authors
Horti AG; Naik R; Foss CA; Minn I; Misheneva V; Du Y; Wang Y; Mathews WB; Wu Y; Hall A
Journal
Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 5, pp. 1686–1691
Publisher
Proceedings of the National Academy of Sciences
Publication Date
January 29, 2019
DOI
10.1073/pnas.1812155116
ISSN
0027-8424