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Social interaction modulates the intensity of...
Journal article

Social interaction modulates the intensity of compulsive checking in a rat model of obsessive-compulsive disorder (OCD)

Abstract

Here we present an empirical study that provides a basis for understanding the impact of the social environment on individuals with mental disorders. Rats treated chronically with the dopamine-agonist quinpirole offer a solid animal model for compulsive behavior that has been comprehensively evaluated and validated in numerous studies. Moreover, the method of behavioral analysis used in the quinpirole rat model has been similarly applied to the …

Authors

Dorfman A; Szechtman H; Eilam D

Journal

Behavioural Brain Research, Vol. 359, , pp. 156–164

Publisher

Elsevier

Publication Date

February 2019

DOI

10.1016/j.bbr.2018.10.038

ISSN

0166-4328