Journal article
Altered colonic function and microbiota profile in a mouse model of chronic depression
Abstract
BACKGROUND: Depression often coexists with the irritable bowel syndrome (IBS) which is characterized by alterations in gut function. There is emerging evidence that the microbial composition (microbiota) of the gut is altered in IBS, but the basis for this is poorly understood. The aim of this study was to determine whether the induction of chronic depression results in changes in the colonic function and in its microbial community, and to …
Authors
Park AJ; Collins J; Blennerhassett PA; Ghia JE; Verdu EF; Bercik P; Collins SM
Journal
Neurogastroenterology & Motility, Vol. 25, No. 9, pp. 733–e575
Publisher
Wiley
Publication Date
September 2013
DOI
10.1111/nmo.12153
ISSN
1350-1925