An approach to feeding high-percentage fish diets to mice for human and wildlife toxicology studies

Experimental feeding of sport fish to rodents has been an important tool for the study of biological effects induced by a contaminated fish diet. Most rodent feeding studies have used low-to-moderate levels of tissue from large fish species incorporated into diets fed to rats and have given little consideration to issues of diet palatability or nutrition. There are currently no rodent diet models suitable for assessing the risk to human …