Journal article
Temporal and spectral differences in the ultrasonic vocalizations of fragile X knock out mice during postnatal development
Abstract
The fmr1 knock out (KO) mouse has been a useful animal model to understand pathology and treatment of FXS, both anatomically and behaviorally. Ultrasonic vocalizations (USVs) are a behavioral tool to assess early life communication deficits in mice. Here, we report on the temporal and spectral features of USVs emitted after maternal separation in wild type (FVB/N) and fmr1 KO pups at postnatal days (P) P4, P7 and P10. The results show changes …
Authors
Lai JKY; Sobala-Drozdowski M; Zhou L; Doering LC; Faure PA; Foster JA
Journal
Behavioural Brain Research, Vol. 259, , pp. 119–130
Publisher
Elsevier
Publication Date
February 2014
DOI
10.1016/j.bbr.2013.10.049
ISSN
0166-4328