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Starvation‐Induced Proximal Gut Mucosal Atrophy...
Journal article

Starvation‐Induced Proximal Gut Mucosal Atrophy Diminished With Aging

Abstract

BACKGROUND: Starvation induces small bowel atrophy with increased intestinal epithelial apoptosis and decreased proliferation. The authors examined these parameters after starvation in aged animals. METHODS: Sixty-four 6-week-old and 26-month-old C57BL/6 mice were randomly assigned to either an ad libitum fed or fasted group. The small bowel was harvested at 12, 48, and 72 hours following starvation. Proximal gut mucosal height was measured and …

Authors

Song J; Wolf SE; Wu X; Finnerty CC; Gauglitz GG; Herndon DN; Jeschke MG

Journal

Journal of Parenteral and Enteral Nutrition, Vol. 33, No. 4, pp. 411–416

Publisher

Wiley

Publication Date

July 2009

DOI

10.1177/0148607108325178

ISSN

0148-6071