Journal article
Inactivation of MuxABC-OpmB transporter system in Pseudomonas aeruginosa leads to increased ampicillin and carbenicillin resistance and decreased virulence
Abstract
Resistance-Nodulation-Cell Division (RND) pumps play important roles in bacterial resistance to antibiotics. Pseudomonas aeruginosa is an important human pathogen which exhibits high level resistance to antibiotics. There are total of 12 RND pumps present in the P. aeruginosa PAOl genome. The recently characterized MuxABC-OpmB system has been shown to play a role in resistance to novobiocin, aztreonam, macrolides, and tetracycline in a multiple …
Authors
Yang L; Chen L; Shen L; Surette M; Duan K
Journal
Journal of Microbiology, Vol. 49, No. 1, pp. 107–114
Publisher
The Microbiological Society of Korea
Publication Date
February 2011
DOI
10.1007/s12275-011-0186-2
ISSN
1225-8873