Journal article
Oestradiol enhances tumour regression induced by B7-1/IL-2 adenoviral gene transfer in a murine model of breast cancer
Abstract
The majority of breast cancers are oestrogen dependent and although current treatment strategies have improved, approximately 50% of the patients will develop metastasis. New treatments that result in long-term systemic immunity are therefore being developed. We have previously shown that adenoviral gene transfer of B7-1/IL-2 to murine breast cancer induces a high rate of complete tumour regression and systemic immunity. Since oestrogens not …
Authors
Dabrosin C; Palmer K; Gauldie J
Journal
British Journal of Cancer, Vol. 89, No. 2, pp. 385–390
Publisher
Springer Nature
Publication Date
July 2003
DOI
10.1038/sj.bjc.6601099
ISSN
0007-0920