Journal article
Role of P2X7 Receptor in an Animal Model of Mania Induced by D-Amphetamine
Abstract
The objective of this study was to explore the association between the P2X7 purinergic receptor (P2X7R) and neuroinflammation using a preclinical model of acute bipolar mania. We analyzed the modulatory effects of P2X7R agonist (3′-O-(4-benzoyl)benzoyl-adenosine 5′-triphosphate, BzATP) and antagonists (brilliant blue, BBG and 3-[[5-(2,3 dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride, A438079) on assessments related to behavior …
Authors
Gubert C; Fries GR; Pfaffenseller B; Ferrari P; Coutinho-Silva R; Morrone FB; Kapczinski F; Battastini AMO
Journal
Molecular Neurobiology, Vol. 53, No. 1, pp. 611–620
Publisher
Springer Nature
Publication Date
January 2016
DOI
10.1007/s12035-014-9031-z
ISSN
0893-7648