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Targeting cellular energy production in...
Journal article

Targeting cellular energy production in neurological disorders.

Abstract

The concepts of energy dysregulation and oxidative stress and their complicated interdependence have rapidly evolved to assume primary importance in understanding the pathophysiology of numerous neurological disorders. Therefore, neuroprotective strategies addressing specific bioenergetic defects hold particular promise in the treatment of these conditions (i.e., amyotrophic lateral sclerosis, Huntington's disease, Parkinson's disease, …

Authors

Baker SK; Tarnopolsky MA

Journal

Expert Opin Investig Drugs, Vol. 12, No. 10, pp. 1655–1679

Publication Date

October 2003

DOI

10.1517/13543784.12.10.1655

ISSN

1354-3784