Journal article
Performance of compulsive behavior in rats is not a unitary phenomenon – validation of separate functional components in compulsive checking behavior
Abstract
A previous analysis of the quinpirole sensitisation rat model of obsessive-compulsive disorder revealed that the behavioral phenotype of compulsive checking consists of three constitutive components - vigor of checking performance, focus on the task of checking, and satiety following a bout of checking. As confirmation of this analysis, the aim of the present study was to reconstitute, without quinpirole treatment, each of the putative …
Authors
Tucci MC; Dvorkin-Gheva A; Johnson E; Cheon P; Taji L; Agarwal A; Foster J; Szechtman H
Journal
European Journal of Neuroscience, Vol. 40, No. 6, pp. 2971–2979
Publisher
Wiley
Publication Date
9 2014
DOI
10.1111/ejn.12652
ISSN
0953-816X