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Peritoneal instillation of taurolidine or...
Journal article

Peritoneal instillation of taurolidine or polihexanide modulates intestinal microcirculation in experimental endotoxemia

Abstract

Background and aimsTreatment of peritonitis may include peritoneal lavage/instillation with anti-infective agents like taurolidine or chlorhexidine.Materials and methodsWe examined the effects of peritoneal instillation (INST, 5-ml solution) with taurolidine (TAURO) or polihexanide (POLI-LS) on intestinal microcirculation using intravital microscopy (IVM) in experimental endotoxemia (15 mg/kg lipopolysaccharide i.v.; LPS) in the rat (n = 8 each …

Authors

Frieling H; Lauer K-S; Gründling M; Usichenko T; Meissner K; Kanellopoulou T; Lehmann C; Wendt M; Pavlovic D

Journal

International Journal of Colorectal Disease, Vol. 22, No. 7, pp. 807–817

Publisher

Springer Nature

Publication Date

July 2007

DOI

10.1007/s00384-006-0239-x

ISSN

0179-1958