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Establishment of T‐Helper‐2 immune response based...
Journal article

Establishment of T‐Helper‐2 immune response based gerbil model of enteric infection

Abstract

BACKGROUND: The reciprocal antagonism of T-helper-1 (Th-1) and Th-2 type immune responses suggests that helminth parasitic infection may ameliorate disease where a Th-1 type response dominates. The Mongolian gerbil has been useful in the investigation of the pathogenesis of gastric cancer, since long-term infection of gerbils with Helicobacter pylori induces adenocarcinoma. In this study the kinetics of worm expulsion and associated immune …

Authors

Sagar M; Padol I; Khan WI; Bonin RP; Blennerhassett PA; Hunt RH

Journal

Scandinavian Journal of Gastroenterology, Vol. 39, No. 7, pp. 668–673

Publisher

Taylor & Francis

Publication Date

January 2004

DOI

10.1080/00365520410005315

ISSN

0036-5521