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A Highly Effective Component Vaccine against...
Journal article

A Highly Effective Component Vaccine against Nontyphoidal Salmonella enterica Infections

Abstract

Nontyphoidal Salmonella enterica (NTS) infections are a major burden to global public health, as they lead to diseases ranging from gastroenteritis to systemic infections and there is currently no vaccine available. Here, we describe a highly effective component vaccine against S. enterica serovar Typhimurium in both gastroenteritis and systemic murine infection models. We devised an approach to generate supernatants of S. enterica serovar …

Authors

Ferreira RBR; Valdez Y; Coombes BK; Sad S; Gouw JW; Brown EM; Li Y; Grassl GA; Antunes LCM; Gill N

Journal

mBio, Vol. 6, No. 5, pp. 10.1128/mbio.01421–10.1128/mbio.01415

Publisher

American Society for Microbiology

Publication Date

October 30, 2015

DOI

10.1128/mbio.01421-15

ISSN

2161-2129