Journal article
BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog
Abstract
The aged canine (dog) is an excellent model for investigating the neurobiological changes that underlie cognitive impairment and neurodegeneration in humans, as canines and humans undergo similar pathological and behavioral changes with aging. Recent evidence indicates that a combination of environmental enrichment and antioxidant-fortified diet can be used to reduce the rate of age-dependent neuropathology and cognitive decline in aged dogs, …
Authors
Fahnestock M; Marchese M; Head E; Pop V; Michalski B; Milgram WN; Cotman CW
Journal
Neurobiology of Aging, Vol. 33, No. 3, pp. 546–554
Publisher
Elsevier
Publication Date
March 2012
DOI
10.1016/j.neurobiolaging.2010.03.019
ISSN
0197-4580