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Measurement of Platelet-Associated IgG in Animal...
Journal article

Measurement of Platelet-Associated IgG in Animal Models of Immune and Nonimmune Thrombocytopenia

Abstract

Abstract Platelet-associated IgG (PAIgG) is elevated in idiopathic thrombocytopenic purpura (ITP), but it also is elevated in other thrombocytopenic disorders traditionally considered to be nonimmune. Consequently it is possible that elevated PAIgG is a nonspecific finding secondary to thrombocytopenia. To study this issue we developed a rabbit model of immune and nonimmune mediated thrombocytopenia. The mechanism of the …

Authors

Arnott J; Horsewood P; Kelton JG

Journal

Blood, Vol. 69, No. 5, pp. 1294–1299

Publisher

American Society of Hematology

Publication Date

May 1, 1987

DOI

10.1182/blood.v69.5.1294.1294

ISSN

0006-4971