Journal article
SseL Is a Salmonella-Specific Translocated Effector Integrated into the SsrB-Controlled Salmonella Pathogenicity Island 2 Type III Secretion System
Abstract
Bacterial pathogens use horizontal gene transfer to acquire virulence factors that influence host colonization, alter virulence traits, and ultimately shape the outcome of disease following infection. One hallmark of the host-pathogen interaction is the prokaryotic type III secretion system that translocates virulence factors into host cells during infection. Salmonella enterica possesses two type III secretion systems that are utilized during …
Authors
Coombes BK; Lowden MJ; Bishop JL; Wickham ME; Brown NF; Duong N; Osborne S; Gal-Mor O; Finlay BB
Journal
Infection and Immunity, Vol. 75, No. 2, pp. 574–580
Publisher
American Society for Microbiology
Publication Date
February 2007
DOI
10.1128/iai.00985-06
ISSN
0019-9567
Associated Experts
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
AnimalsBacterial ProteinsCell LineCytoplasmDisease Models, AnimalEpithelial CellsFlow CytometryGene DeletionGene Expression Regulation, BacterialGenomic IslandsHumansMacrophagesMiceMice, Inbred C57BLMutagenesis, InsertionalOligonucleotide Array Sequence AnalysisProtein TransportSalmonella Infections, AnimalSalmonella typhimuriumTranscription FactorsVirulence Factors