Dissociating basal forebrain and medial temporal amnesic syndromes: Insights from classical conditioning

In humans, anterograde amnesia can result from damage to the medical temporal (MT) lobes (including hippocampus), as well as to other brain areas such as basal forebrain. Results from animal classical conditioning studies suggest that there may be qualitative differences in the memory impairment following MT vs. basal forebrain damage. Specifically, delay eyeblink conditioning is spared after MT damage in animals and humans, but impaired in …