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Delayed Onset of Changes in Soma Action Potential...
Journal article

Delayed Onset of Changes in Soma Action Potential Genesis in Nociceptive A-Beta DRG Neurons in Vivo in a Rat Model of Osteoarthritis

Abstract

BACKGROUND: Clinical data on osteoarthritis (OA) suggest widespread changes in sensory function that vary during the progression of OA. In previous studies on a surgically-induced animal model of OA we have observed that changes in structure and gene expression follow a variable trajectory over the initial days and weeks. To investigate mechanisms underlying changes in sensory function in this model, the present electrophysiological study …

Authors

Wu Q; Henry JL

Journal

Molecular Pain, Vol. 5, ,

Publisher

SAGE Publications

Publication Date

January 1, 2009

DOI

10.1186/1744-8069-5-57

ISSN

1744-8069