Journal article
Communicating hydrocephalus in adult rats with kaolin obstruction of the basal cisterns or the cortical subarachnoid space
Abstract
Communicating hydrocephalus (CH) occurs frequently, but clinically-relevant animal models amenable to diagnostic imaging and cerebrospinal fluid shunting are not available. In order to develop and characterize models of subarachnoid space (SAS) obstruction at the basal cisterns (BC) or cerebral convexities (CX), 25% kaolin was injected in adult female Sprague-Dawley rats following halothane anesthesia; intact- or saline-injected animals served …
Authors
Li J; McAllister JP; Shen Y; Wagshul ME; Miller JM; Egnor MR; Johnston MG; Haacke EM; Walker ML
Journal
Experimental Neurology, Vol. 211, No. 2, pp. 351–361
Publisher
Elsevier
Publication Date
June 2008
DOI
10.1016/j.expneurol.2007.12.030
ISSN
0014-4886