Signal Transduction - McMaster Experts

subject area of

1,25-Dihydroxyvitamin D3Primes Acute Promyelocytic Cells for TPA-Induced Monocytic Differentiation through Both PKC and Tyrosine Phosphorylation Cascades Journal Articles
1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells Journal Articles
2-[125I]Iodomelatonin Binding in the Brains of Four Salmonids Journal Articles
2017 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis Journal Articles
4-phenylbutyrate and valproate treatment attenuates the progression of atherosclerosis and stabilizes existing plaques Journal Articles
8-isoprostaglandin E2 activates Ca2+-dependent K+ current via cyclic AMP signaling pathway in murine renal artery Journal Articles
AJP-Cell Physiology begins a new Theme of Reviews on “Inflammation: From Cellular Mechanisms to Immune Cell Education” Journal Articles
Chlamydia pneumoniae Infection of Human Endothelial Cells Induces Proliferation of Smooth Muscle Cells via an Endothelial Cell-Derived Soluble Factor(s) Journal Articles
Cynara scolymus affects malignant pleural mesothelioma by promoting apoptosis and restraining invasion Journal Articles
Salmonella entericaSerovar Typhimurium Exploits Toll-Like Receptor Signaling during the Host-Pathogen Interaction Journal Articles
IL‐6 mediates ER expansion during hyperpolarization of alternatively activated macrophages Journal Articles
OX40L blockade and allergen‐induced airway responses in subjects with mild asthma Journal Articles
Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis Journal Articles
PhoR autokinase activity is controlled by an intermediate in wall teichoic acid metabolism that is sensed by the intracellular PAS domain during the PhoPR‐mediated phosphate limitation response of Bacillus subtilis Journal Articles
cTAZ : a safeguard factor of antiviral response Journal Articles
A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease Journal Articles
A Dietary Supplement Abolishes Age-Related Cognitive Decline in Transgenic Mice Expressing Elevated Free Radical Processes Journal Articles
A Hydroponic Co-cultivation System for Simultaneous and Systematic Analysis of Plant/Microbe Molecular Interactions and Signaling Journal Articles
A Mechanism of Extreme Growth and Reliable Signaling in Sexually Selected Ornaments and Weapons Journal Articles
A PPARγ mutant serves as a dominant negative inhibitor of PPAR signaling and is localized in the nucleus Journal Articles
A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation Journal Articles
A STAT3-NFkB/DDIT3/CEBPβ axis modulates ALDH1A3 expression in chemoresistant cell subpopulations Journal Articles
A by-product of glutathione production in cancer cells may cause disruption in bone metabolic processesThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease. Journal Articles
A design logic for sequential segmentation across organisms. Journal Articles
A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials Journal Articles
A general mechanism for conditional expression of exaggerated sexually‐selected traits Journal Articles
A hybrid model to study how late long-term potentiation is affected by faulty molecules in an intraneuronal signaling network regulating transcription factor CREB Journal Articles
A large-scale candidate gene association study of age at menarche and age at natural menopause Journal Articles
A macrophage-stimulating compound from a screen of microbial natural products Journal Articles
A novel function for the competence inducing peptide, XIP, as a cell death effector ofStreptococcus mutans Journal Articles
A novel profibrotic mechanism mediated by TGFβ‐stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells Journal Articles
A p56 Ligand Serves as a Coactivator of an Orphan Nuclear Hormone Receptor Journal Articles
A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients. Journal Articles
A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia Journal Articles
A putative Lipid Transfer Protein involved in systemic resistance signaling in Arabidopsis Journal Articles
A quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model Journal Articles
A randomized, placebo‐controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER) Journal Articles
A role for the TGFβ-Par6 polarity pathway in breast cancer progression Journal Articles
A role for the scavenger receptor, class B type I in high density lipoprotein dependent activation of cellular signaling pathways Journal Articles
A role of SIPL1/SHARPIN in promoting resistance to hormone therapy in breast cancer Journal Articles
A screen of kinase inhibitors reveals a potential role of Chk1 in regulating Hydra head regeneration and maintenance Journal Articles
A set of NF-κB–regulated microRNAs induces acquired TRAIL resistance in Lung cancer Journal Articles
A single dose of exercise stimulates skeletal muscle mitochondrial plasticity in myotonic dystrophy type 1 Journal Articles
A translational view of the genetics of lipodystrophy and ectopic fat deposition. Chapters
ABCF1 Regulates dsDNA-induced Immune Responses in Human Airway Epithelial Cells Journal Articles
AHNAK deficiency promotes browning and lipolysis in mice via increased responsiveness to β-adrenergic signalling Journal Articles
AHR signaling is induced by infection with coronaviruses Journal Articles
AMP-activated protein kinase (AMPK) beyond metabolism Journal Articles
AMP-activated protein kinase: the current landscape for drug development Journal Articles
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity Journal Articles
AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis Journal Articles
AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation Journal Articles
AMPK‐dependent hormonal regulation of whole‐body energy metabolism Journal Articles
AMPK‐independent pathways regulate skeletal muscle fatty acid oxidation Journal Articles
AMP‐activated protein kinase is required for exercise‐induced peroxisome proliferator‐activated receptor γ co‐activator 1α translocation to subsarcolemmal mitochondria in skeletal muscle Journal Articles
AP-2α knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis Journal Articles
ASK1 inhibitors are potential pan-antiviral drugs, which dampen replication of diverse viruses including SARS-CoV2 Journal Articles
ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres Journal Articles
ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes Journal Articles
ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence Journal Articles
Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia Journal Articles
Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients Journal Articles
Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish Journal Articles
Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy Journal Articles
Abundance of cyclin B1 regulates γ-radiation–induced apoptosis Journal Articles
Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression Journal Articles
Actions of vasopressin and the Ca(2+)-ATPase inhibitor, thapsigargin, on Ca2+ signaling in hepatocytes. Journal Articles
Activated MKK3/MYC crosstalk impairs dabrafenib response in BRAFV600E colorectal cancer leading to resistance Journal Articles
Activated calcineurin ameliorates contraction‐induced injury to skeletal muscles of mdx dystrophic mice Journal Articles
Activation of ER stress signalling increases mortality after a major trauma Journal Articles
Activation of mesangial cell signaling cascades in response to mechanical strain Journal Articles
Activation of the Hedgehog Signaling Pathway in the Developing Lens Stimulates EctopicFoxE3Expression and Disruption in Fiber Cell Differentiation Journal Articles
Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis Journal Articles
Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease Journal Articles
Activity Regulates Positive and Negative Neurotrophin-Derived Signals to Determine Axon Competition Journal Articles
Activity and expression of Xenopus laevis matrix metalloproteinases: Identification of a novel role for the hormone prolactin in regulating collagenolysis in both amphibians and mammals Journal Articles
Addressing Taxane Resistance in Metastatic Castration-Resistant Prostate Cancer: A Focus On Chaperone Proteins Journal Articles
Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway Journal Articles
Adiponectin inhibits oxidative stress in human prostate carcinoma cells Journal Articles
Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy Journal Articles
Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats Journal Articles
Adipose tissue as an endocrine organ Journal Articles
Administration of dexamethasone protects mice against ischemia/reperfusion induced renal injury by suppressing PI3K/AKT signaling. Journal Articles
Age-Related Resistance in Arabidopsis Is a Developmentally Regulated Defense Response to Pseudomonas syringae Journal Articles
Ahnak depletion accelerates liver regeneration by modulating the TGF-β/Smad signaling pathway Journal Articles
Airway smooth muscle in asthma: Phenotype plasticity and function Conferences
Akt Mediates Mechanical Strain-Induced Collagen Production by Mesangial Cells Journal Articles
Alcohol Ingestion Impairs Maximal Post-Exercise Rates of Myofibrillar Protein Synthesis following a Single Bout of Concurrent Training Journal Articles
Allergen-induced increase in bone marrow progenitors in airway hyperresponsive dogs: regulation by a serum hemopoietic factor. Journal Articles
Allergic inflammation triggers dyslipidemia via IgG signalling Journal Articles
Allosteric pluripotency: challenges and opportunities Journal Articles
Alterations in Skeletal Muscle Cell Homeostasis in a Mouse Model of Cigarette Smoke Exposure Journal Articles
Alterations of immune response of non-small cell lung cancer with Azacytidine Journal Articles
Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling Journal Articles
Amplification of MUC1 in prostate cancer metastasis and CRPC development Journal Articles
Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis Journal Articles
An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity Journal Articles
An emerging role for Wnt and GSK3 signaling pathways in schizophrenia Journal Articles
An inducible model of human amylin overexpression reveals diverse transcriptional changes Journal Articles
Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture Journal Articles
Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise Journal Articles
Analysis of the Human Fetal Liver Hematopoietic Microenvironment Journal Articles
Androgen Induces Adaptation to Oxidative Stress in Prostate Cancer: Implications for Treatment with Radiation Therapy Journal Articles
Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression Journal Articles
Angiogenesis in the Placenta: The Role of Reactive Oxygen Species Signaling Journal Articles
Angiotensin II mobilizes intracellular calcium and activates pannexin‐1 channels in rat carotid body type II cells via AT₁ receptors Journal Articles
Anormalidades neuropatológicas e neuroquímicas no transtorno afetivo bipolar Journal Articles
Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions Journal Articles
Anti-Inflammatory Effects of Tanshinone IIA on Atherosclerostic Vessels of Ovariectomized ApoE-/- Mice are Mediated by Estrogen Receptor Activation and Through the ERK Signaling Pathway Journal Articles
Anti-pneumococcal deficits of monocyte-derived macrophages from the advanced-age, frail elderly and related impairments in PI3K-AKT signaling Journal Articles
Antialarmins for treatment of asthma Journal Articles
Antibodies to rat soluble IL‐6 receptor stimulate B9 hybridoma cell proliferation Journal Articles
Antifibrotic Role of αB-Crystallin Inhibition in Pleural and Subpleural Fibrosis Journal Articles
Antiplatelet Effect of Active Components Derived from Chinese Herbal Medicine Journal Articles
Apoptosis induction by eIF5A1 involves activation of the intrinsic mitochondrial pathway Journal Articles
Apoptosis is initiated in human keratinocytes exposed to signalling factors from microbeam irradiated cells Journal Articles
Apoptosis is signalled early by low doses of ionising radiation in a radiation-induced bystander effect Journal Articles
Arachidonic Acid Metabolism and Kidney Inflammation. Journal Articles
Are SIRT1 activators another indirect method to increase AMPK for beneficial effects on aging and the metabolic syndrome? Journal Articles
Are endothelium-derived hyperpolarizing and contracting factors isoprostanes? Journal Articles
Argos and Spitz group genes function to regulate midline glial cell number in Drosophila embryos Journal Articles
Arkadia enhances nodal-related signalling to induce mesendoderm. Journal Articles
Aryl hydrocarbon receptor control of a disease tolerance defence pathway Journal Articles
Association of Interleukin-6 Signalling with the Muscle Stem Cell Response Following Muscle-Lengthening Contractions in Humans Journal Articles
Association of Phosphorylated Epidermal Growth Factor Receptor with Survival in Patients with Locally Advanced Non-small Cell Lung Cancer Treated with Radiotherapy Journal Articles
Asthma therapy: how far have we come, why did we fail and where should we go next? Journal Articles
Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis Journal Articles
Atorvastatin Delays Murine Platelet Activation In Vivo Even in the Absence of Endothelial NO Synthase Journal Articles
Axon repulsion from the midline of the Drosophila CNS requires slit function Journal Articles
B Cell Maintenance of Subcapsular Sinus Macrophages Protects against a Fatal Viral Infection Independent of Adaptive Immunity Journal Articles
B7RP-1 Is Not Required for the Generation of Th2 Responses in a Model of Allergic Airway Inflammation but Is Essential for the Induction of Inhalation Tolerance Journal Articles
BDNF/TrkB Content and Interaction with Gastrin-Releasing Peptide Receptor Blockade in Colorectal Cancer Journal Articles
BH3-only proteins: Orchestrators of apoptosis Journal Articles
BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer Journal Articles
Bacterial Peptidoglycan Stimulates Adipocyte Lipolysis via NOD1 Journal Articles
Bacterial lipids Journal Articles
Basic and Translational Research in Intracerebral Hemorrhage Journal Articles
Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line Journal Articles
Beneficial effects of resveratrol on respiratory chain defects in patients' fibroblasts involve estrogen receptor and estrogen-related receptor alpha signaling Journal Articles
Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and prostaglandin E2 (PGE2) output Journal Articles
Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways Journal Articles
Binding of Anti-GRP78 Autoantibodies to Cell Surface GRP78 Increases Tissue Factor Procoagulant Activity via the Release of Calcium from Endoplasmic Reticulum Stores Journal Articles
Bio-acoustic signaling; exploring the potential of sound as a mediator of low-dose radiation and stress responses in the environment Journal Articles
Bioactive Molecules and Their Mechanisms of Action. Journal Articles
Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region Journal Articles
Bisphosphonates Target B Cells to Enhance Humoral Immune Responses Journal Articles
Bone Morphogenetic Proteins Regulate the Developmental Program of Human Hematopoietic Stem Cells Journal Articles
Bone cancer-induced pain is associated with glutamate signalling in peripheral sensory neurons Journal Articles
Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract Journal Articles
Burn-induced hypermetabolism and skeletal muscle dysfunction Journal Articles
Bystander effects of ionizing radiation can be modulated by signaling amines Journal Articles
Bystander signal production and response are independent processes which are cell line dependent Journal Articles
Bystander-induced differentiation: A major response to targeted irradiation of a urothelial explant model Journal Articles
C. elegans electrotaxis behavior is modulated by heat shock response and unfolded protein response signaling pathways Journal Articles
CARM1 drives mitophagy and autophagy flux during fasting-induced skeletal muscle atrophy Journal Articles
CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection Journal Articles
CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence Journal Articles
CD200-dependent and nonCD200-dependant pathways of NK cell suppression by human IVIG Journal Articles
CD23-mediated transport of IgE/immune complexes across human intestinal epithelium: role of p38 MAPK Journal Articles
CD4⁺ T‐cell‐mediated anti‐tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis Journal Articles
CDC42 regulates the expression of superficial zone molecules in part through the actin cytoskeleton and myocardin‐related transcription factor‐A Journal Articles
CLASSIC IL-6 SIGNALING IS ASSOCIATED WITH POOR OUTCOMES IN BURN PATIENTS Journal Articles
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK Journal Articles
CO₂/pH Chemosensory Signaling in Co-Cultures of Rat Carotid Body Receptors and Petrosal Neurons: Role of ATP and ACh Journal Articles
COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux Journal Articles
CXCL12/CXCR4 Signaling Enhances Human PSC-Derived Hematopoietic Progenitor Function and Overcomes Early In Vivo Transplantation Failure Journal Articles
CXCL9 Contributes to Antimicrobial Protection of the Gut during Citrobacter rodentium Infection Independent of Chemokine-Receptor Signaling Journal Articles
CXCR3 Signaling Is Required for Restricted Homing of Parenteral Tuberculosis Vaccine–Induced T Cells to Both the Lung Parenchyma and Airway Journal Articles
CYFIP/Sra-1 Controls Neuronal Connectivity in Drosophila and Links the Rac1 GTPase Pathway to the Fragile X Protein Journal Articles
Ca²⁺/calmodulin-dependent protein kinase IIβ and IIδ mediate TGFβ-induced transduction of fibronectin and collagen in human pulmonary fibroblasts Journal Articles
Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β Journal Articles
Caenorhabditis elegans SMA-10/LRIG Is a Conserved Transmembrane Protein that Enhances Bone Morphogenetic Protein Signaling Journal Articles
Calcium Regulation and Contractile Dysfunction of Smooth Muscle Journal Articles
Caloxin: a novel plasma membrane Ca²⁺ pump inhibitor Journal Articles
Canadian Association of Neurosciences Review: Polyglutamine Expansion Neurodegenerative Diseases Journal Articles
Cancer phenomics: RET and PTEN as illustrative models Journal Articles
Canonical WNT/β-catenin signaling is required for ureteric branching Journal Articles
Captopril treatment induces hyperplasia but inhibits myonuclear accretion following severe myotrauma in murine skeletal muscle Journal Articles
Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans Journal Articles
Carotid Body Adaptation to Hypoxia: Cellular and Molecular Mechanisms in vitro Journal Articles
Case Report: Eosinophilic Esophagitis in a Patient With a Novel STAT1 Gain-of-Function Pathogenic Variant Journal Articles
Caspase-12 Dampens the Immune Response to Malaria Independently of the Inflammasome by Targeting NF-κB Signaling Journal Articles
Caveolin-1 in the Pathogenesis of Diabetic Nephropathy: Potential Therapeutic Target? Journal Articles
Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy Journal Articles
Cell-free Tumor Microparticle Vaccines Stimulate Dendritic Cells via cGAS/STING Signaling Journal Articles
Cells Exposed to Sublethal Oxidative Stress Selectively Attract Monocytes/Macrophages via Scavenger Receptors and MyD88-Mediated Signaling Journal Articles
Cellular Metabolic Homeostasis During Large-Scale Change in Atp Turnover Rates in Muscles Journal Articles
Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness Journal Articles
Cellular metabolic homeostasis during large-scale change in ATP turnover rates in muscles. Journal Articles
Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function Journal Articles
Changes in HIF-1α protein, pyruvate dehydrogenase phosphorylation, and activity with exercise in acute and chronic hypoxia Journal Articles
Changes in expression of theCD200 tolerance‐signaling molecule and its receptor (CD200R) by villus trophoblasts during first trimester missed abortion and in chronic histiocytic intervillositis Journal Articles
Chapter 7 Evidence that the Merkel cell is not the transducer in the mechanosensory Merkel cell – neurite complex Journal Articles
Characterization of Chemokine Receptors Expressed in Primitive Blood Cells During Human Hematopoietic Ontogeny Journal Articles
Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C Journal Articles
Characterization of Radioprotective, Radiomitigative and Bystander Signaling Modulating Effects of Endogenous Metabolites – Phenylacetate, Ursodeoxycholate and Tauroursodeoxycholate – on HCT116 Human Colon Carcinoma Cell Line Journal Articles
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance Journal Articles
Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells Journal Articles
Characterizing the Role of Glycogen Synthase Kinase-3α/β in Macrophage Polarization and the Regulation of Pro-Atherogenic Pathways in Cultured Ldlr-/- Macrophages Journal Articles
Chemical Interactions between Organisms in Microbial Communities Journal Articles
Chemosensing and signal transduction in bacteria Journal Articles
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signaling. Journal Articles
Chlamydiae Host Cell Interactions Revealed Using DNA Microarrays Journal Articles
Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle Journal Articles
Chronic modulation of AMP-Kinase, Akt and mTOR pathways by ionizing radiation in human lung cancer xenografts Journal Articles
Cigarette Smoke Exposure Triggers the Autophagic Cascade via Activation of the AMPK Pathway in Mice1 Journal Articles
Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis inSmad3knockout mice Journal Articles
Cigarette smoke upregulates pulmonary vascular matrix metalloproteinases via TNF-α signaling Journal Articles
Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice Journal Articles
Ciliary Neurotrophic Factor Suppresses Hypothalamic AMP-Kinase Signaling in Leptin-Resistant Obese Mice Journal Articles
Circulating Peroxiredoxin-1 is a novel damage-associated molecular pattern and aggravates acute liver injury via promoting inflammation Journal Articles
Class A Scavenger Receptor–Mediated Double-Stranded RNA Internalization Is Independent of Innate Antiviral Signaling and Does Not Require Phosphatidylinositol 3-Kinase Activity Journal Articles
Classification, hepatotoxic mechanisms, and targets of the risk ingredients in traditional Chinese medicine-induced liver injury Journal Articles
Clinical Implications of Targeting the JAK-STAT Pathway in Psoriatic Disease: Emphasis on the TYK2 Pathway Journal Articles
Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia Journal Articles
Collagen I induction by high glucose levels is mediated by epidermal growth factor receptor and phosphoinositide 3-kinase/Akt signalling in mesangial cells Journal Articles
Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer Journal Articles
Combinatorial therapeutic activation with heparin and AICAR stimulates additive effects on utrophin A expression in dystrophic muscles Journal Articles
Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development Journal Articles
Communication in bacteria: an ecological and evolutionary perspective Journal Articles
Communication of Radiation-Induced Signals in Vivo between DNA Repair Deficient and Proficient Medaka (Oryzias latipes) Journal Articles
Communication of ionising radiation signals – a tale of two fish Journal Articles
Comparative Proteomics Analysis of Arabidopsis Phloem Exudates Collected During the Induction of Systemic Acquired Resistance Journal Articles
Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer Journal Articles
Comparative transcriptome analysis ofAgrobacterium tumefaciensin response to plant signal salicylic acid, indole-3-acetic acid and γ-amino butyric acid reveals signalling cross-talk andAgrobacterium-plant co-evolution Journal Articles
Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress Journal Articles
Competence for collagenase gene expression by tissue fibroblasts requires activation of an interleukin 1 alpha autocrine loop. Journal Articles
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma Journal Articles
Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells Journal Articles
Conditioned medium from hypoxia-treated adipocytes renders muscle cells insulin resistant Journal Articles
Conserved Features and Evolutionary Shifts of the EDA Signaling Pathway Involved in Vertebrate Skin Appendage Development Journal Articles
Conserved mechanism of Wnt signaling function in the specification of vulval precursor fates in C. elegans and C. briggsae Journal Articles
Contactin 1: An Important and Emerging Oncogenic Protein Promoting Cancer Progression and Metastasis Journal Articles
Contraction-related stimuli regulate GLUT4 traffic in C₂C₁₂-GLUT4mycskeletal muscle cells Journal Articles
Control of Pathogenic CD4 T Cells and Lethal Immunopathology by Signaling Immunoadaptor DAP12 during Influenza Infection Journal Articles
Controlling skeletal muscle CPT-I malonyl-CoA sensitivity: the importance of AMPK-independent regulation of intermediate filaments during exercise Journal Articles
Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma Journal Articles
Converging purinergic and immune signaling pathways drive IL-6 secretion by Fragile X cortical astrocytes via STAT3 Journal Articles
Cooperation in signal transduction of extracellular guanosine 5′ triphosphate and nerve growth factor in neuronal differentiation of PC12 cells Journal Articles
Coordinated Regulation of Two Independent Cell-Cell Signaling Systems and Swarmer Differentiation inSalmonella entericaSerovar Typhimurium Journal Articles
Coordination of metabolic plasticity in skeletal muscle Journal Articles
Corneal development: Role of the periocular mesenchyme and bi-directional signaling Journal Articles
Critical Illness-Related Corticosteroid Insufficiency (CIRCI): A Narrative Review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM) Journal Articles
Critical Role of Natural Killer Cells in Lung Immunopathology During Influenza Infection in Mice Journal Articles
Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM) Journal Articles
Cross-species transcriptomic analysis elucidates constitutive aryl hydrocarbon receptor activity. Journal Articles
Cross-talk between Orphan Nuclear Hormone Receptor RZRα and Peroxisome Proliferator-activated Receptor α in Regulation of the Peroxisomal Hydratase-Dehydrogenase Gene Journal Articles
Crosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis Journal Articles
Crosstalk between the Unfolded Protein Response and NF-κB-Mediated Inflammation in the Progression of Chronic Kidney Disease Journal Articles
Crosstalk between the thyroid hormone and peroxisome proliferator-activated receptors in regulating peroxisome proliferator-responsive genes Journal Articles
Cytokine Regulation of AMPK signalling Journal Articles
Cytokine control of acute phase protein expression. Journal Articles
Cytokine-Induced Hepatic Apoptosis Is Dependent on FGL2/Fibroleukin: The Role of Sp1/Sp3 and STAT1/PU.1 CompositecisElements Journal Articles
Cytokines and Growth Factors Involved in Peritoneal Fibrosis of Peritoneal Dialysis Patients Journal Articles
Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130) Journal Articles
DNA Repair Signaling of Huntingtin: The Next Link Between Late-Onset Neurodegenerative Disease and Oxidative DNA Damage Journal Articles
Dancing in and out of the nucleus: p120ctn and the transcription factor Kaiso Journal Articles
Danger, diversity and priming in innate antiviral immunity Journal Articles
Deconstructing human embryonic stem cell cultures: niche regulation of self-renewal and pluripotency Journal Articles
Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis Journal Articles
Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Is the Result of Altered Notch Signaling Journal Articles
Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid Journal Articles
Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts Journal Articles
Deletion of MAP2K2/MEK2: a novel mechanism for a RASopathy? Journal Articles
Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice Journal Articles
Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis Journal Articles
Differences between platelet phosphoinositide metabolism stimulated by thrombin or SFLLRN are not accounted for by interaction of thrombin with glycoprotein Ib Journal Articles
Differences in Functional Consequences and Signal Transduction Induced by IL-3, IL-5, and Nerve Growth Factor in Human Basophils Journal Articles
Differences in the Hepatic Signal Transcription Pathway and Cytokine Expression Between Thermal Injury and Sepsis Journal Articles
Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle Journal Articles
Differential regulation of striatal G protein levels following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration in C57 BL/6 mice Journal Articles
Dimerization Is Required for the Activity of the Protein Histidine Kinase CheA That Mediates Signal Transduction in Bacterial Chemotaxis Journal Articles
Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance Journal Articles
Diminished contraction‐induced intracellular signaling towards mitochondrial biogenesis in aged skeletal muscle Journal Articles
Direct Microbicidal Activity of Cytotoxic T-Lymphocytes Journal Articles
Directed differentiation of neural cells to hypothalamic dopaminergic neurons Journal Articles
Disassembly of the actin network inhibits insulin-dependent stimulation of glucose transport and prevents recruitment of glucose transporters to the plasma membrane. Journal Articles
Disordered Regions Flanking Ordered Domains Modulate Signaling Transduction Journal Articles
Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling Journal Articles
Disruption of β-catenin/CBP signaling inhibits human airway epithelial–mesenchymal transition and repair Journal Articles
Disruptive physiology: olfaction and the microbiome–gut–brain axis Journal Articles
Dissociation of AMPK activity and ACCβ phosphorylation in human muscle during prolonged exercise Journal Articles
Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression Journal Articles
Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice Journal Articles
Distinguishing Between Mouse and Human Pluripotent Stem Cell Regulation: The Best Laid Plans of Mice and Men Journal Articles
Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development Journal Articles
Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation Journal Articles
Dual Pathway for Promotion of Stem Cell Neural Differentiation Mediated by Gold Nanocomposites Journal Articles
Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract Journal Articles
Dual roles of parathyroid hormone related protein in TGF-β1 signaling and fibronectin up-regulation in mesangial cells Journal Articles
Dual-action peptides: a new strategy in the treatment of diabetes-associated neuropathy Journal Articles
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human Journal Articles
Dysfunctional Nrf2–Keap1 redox signaling in skeletal muscle of the sedentary old Journal Articles
Dysregulated Purinergic Signalling in Fragile X Syndrome Cortical Astrocytes. Journal Articles
Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK Journal Articles
EGF Decreases the Abundance of MicroRNAs That Restrain Oncogenic Transcription Factors Journal Articles
EMT signaling: potential contribution of CRISPR/Cas gene editing Journal Articles
EMT signaling: potential contribution of CRISPR/Cas gene editing. Journal Articles
ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response. Journal Articles
Early Intraplatelet Signaling Enhances the Release of Human Platelet PAR-1 and -4 Amino-Terminal Peptides in Response to Thrombin Journal Articles
Early cardiac development: A Wnt beat away Journal Articles
Eccentric Exercise Activates Novel Transcriptional Regulation of Hypertrophic Signaling Pathways Not Affected by Hormone Changes Journal Articles
Editorial: You give me fever: transcriptional responses to LPS Journal Articles
Effect of dose rate on the radiation-induced bystander response Journal Articles
Effect of gamma radiation on the production of bystander signals from three earthworm species irradiated in vivo Journal Articles
Effects of Activators of Different Intracellular Signaling Pathways on Steroid Production by Goldfish Vitellogenic Ovarian Follicles Journal Articles
Effects of Chronic Treatment of Haloperidol and Clozapine on Levels of G-Protein Subunits in Rat Striatum Journal Articles
Effects of Dystrophin Isoforms on Signal Transduction through Neural Retina: Genotype–Phenotype Analysis of Duchenne Muscular Dystrophy Mouse Mutants Journal Articles
Effects of Maternal Dexamethasone Treatment Early in Pregnancy on Glucocorticoid Receptors in the Ovine Placenta Journal Articles
Effects of MeCh, thapsigargin, and La3+ on plasmalemmal and intracellular Ca2+ transport in lacrimal acinar cells Journal Articles
Effects of Reactive Oxygen and Nitrogen Species on TrkA Expression and Signalling: Implications for proNGF in Aging and Alzheimer’s Disease Journal Articles
Effects of biomaterial-induced inflammation on fibrosis and rejection Journal Articles
Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes Journal Articles
Elevated SOCS3 and altered IL-6 signaling is associated with age-related human muscle stem cell dysfunction Journal Articles
Elevated basal transcription can underlie timothy channel association with autism related disorders Journal Articles
Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule Journal Articles
Endocrine responses to environmental variation Journal Articles
Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis Journal Articles
Endoplasmic reticulum stress and insulin resistance post‐trauma: similarities to type 2 diabetes Journal Articles
Endothelin-1, but not angiotensin II, induces afferent arteriolar myosin diphosphorylation as a potential contributor to prolonged vasoconstriction Journal Articles
Endurance training partially reverses dietary-induced leptin resistance in rodent skeletal muscle Journal Articles
Energy-stress-mediated AMPK activation inhibits ferroptosis Journal Articles
Enhanced Amino Acid Sensitivity of Myofibrillar Protein Synthesis Persists for up to 24 h after Resistance Exercise in Young Men1–3 Journal Articles
Enhanced BDNF signalling following chronic hypoxia potentiates catecholamine release from cultured rat adrenal chromaffin cells Journal Articles
Enhanced Lipid Oxidation and Maintenance of Muscle Insulin Sensitivity Despite Glucose Intolerance in a Diet-Induced Obesity Mouse Model Journal Articles
Enhanced TH17 Responses in Patients with IL10 Receptor Deficiency and Infantile-onset IBD Journal Articles
Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662 Journal Articles
Enhanced adenosine A_2b receptor signaling facilitates stimulus-induced catecholamine secretion in chronically hypoxic carotid body type I cells Journal Articles
Epidermal Growth Factor Receptor and Transforming Growth Factor-β Signaling Contributes to Variation for Wing Shape in Drosophila melanogaster Journal Articles
Epidermal Growth Factor Receptor: Pathway, Therapies, and Pipeline Journal Articles
Epidermal Growth Factor–Like Domain 7 Is a Novel Inhibitor of Neutrophil Adhesion to Coronary Artery Endothelial Cells Injured by Calcineurin Inhibition Journal Articles
Epidermal growth factor receptor deficiency: Expanding the phenotype beyond infancy Journal Articles
Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1 Journal Articles
Epigenetic Regulation of SOX9 by the NF-κB Signaling Pathway in Pancreatic Cancer Stem Cells Journal Articles
Epigenetic induction of melatonin MT 1 receptors by valproate: Neurotherapeutic implications Journal Articles
Epigenetic mechanisms of melatonin action in human SH-SY5Y neuroblastoma cells Journal Articles
Epigenetic silencing of miR-145-5p contributes to brain metastasis Journal Articles
Estrogen Receptor β Is a Novel Target in Acute Myeloid Leukemia Journal Articles
Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors Journal Articles
Estrogen-Dependent Dynamic Profile of eNOS-DNA Associations in Prostate Cancer Journal Articles
Ethylenecarbodiimide-Fixed Donor Splenocyte Infusions Differentially Target Direct and Indirect Pathways of Allorecognition for Induction of Transplant Tolerance Journal Articles
Evasive Maneuvers by Secreted Bacterial Proteins to Avoid Innate Immune Responses Journal Articles
Evidence That the Epidermal Growth Factor Receptor on Host Cells Confers Reovirus Infection Efficiency Journal Articles
Evidence for P2-purinoceptors contribution in H2O2-induced contraction of rat aorta in the absence of endothelium Journal Articles
Evidence for a direct action of melatonin on the immune system. Journal Articles
Evidence for a protective response by the gill proteome of rainbow trout exposed to X‐ray induced bystander signals Journal Articles
Evidence for neuronal expression of functional Fc (ε and γ) receptors Journal Articles
Evidence for protein kinase involvement in the 5‐HT–[Ca²⁺]_i–pannexin‐1 signalling pathway in type II glial cells of the rat carotid body Journal Articles
Evidence for the role of AMPK in regulating PGC‐1 alpha expression and mitochondrial proteins in mouse epididymal adipose tissue Journal Articles
Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differences Journal Articles
Exercise-induced Protein Arginine Methyltransferase Expression in Skeletal Muscle Journal Articles
Exercise-induced beige adipogenesis of iWAT in Cidea reporter mice Journal Articles
Exercise-specific adaptations in human skeletal muscle: Molecular mechanisms of making muscles fit and mighty. Journal Articles
Exercise‐stimulated interleukin‐15 is controlled byAMPKand regulates skin metabolism and aging Journal Articles
Expanding Role of Dopaminergic Inhibition in Hypercapnic Responses of Cultured Rat Carotid Body Cells: Involvement of Type II Glial Cells Journal Articles
Expanding role of ATP as a versatile messenger at carotid and aortic body chemoreceptors Journal Articles
Exploration of trade-offs between steady-state and dynamic properties in signaling cycles Journal Articles
Expression of Multiple P2X Receptors by Glossopharyngeal Neurons Projecting to Rat Carotid Body O₂-Chemoreceptors: Role in Nitric Oxide-Mediated Efferent Inhibition Journal Articles
Expression of P2X2 and P2X3 receptor subunits in rat carotid body afferent neurones: role in chemosensory signalling Journal Articles
Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3 Journal Articles
Expression of survivin and p16INK4a/Cdk6/pRB proteins and induction of apoptosis in response to radiation and cisplatin in meningioma cells Journal Articles
Expression of the β4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells Journal Articles
Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors Journal Articles
Extracellular DNA and histones: double‐edged swords in immunothrombosis Journal Articles
Extracellular matrix regulates human airway smooth muscle cell migration Journal Articles
Extrinsic signals determine myeloid-erythroid lineage switch in MN1 leukemia Journal Articles
FGF-Regulated Etv Genes Are Essential for Repressing Shh Expression in Mouse Limb Buds Journal Articles
Fc Gamma Receptor Signaling in Mast Cells Links Microbial Stimulation to Mucosal Immune Inflammation in the Intestine Journal Articles
Fetal and Neonatal Exposure to Nicotine Disrupts Postnatal Lung Development in Rats: Role of VEGF and Its Receptors Journal Articles
Fetal growth interacts with multilocus genetic score reflecting dopamine signaling capacity to predict spontaneous sugar intake in children Journal Articles
Filamin A regulates monocyte migration through Rho small GTPases during osteoclastogenesis Journal Articles
FimH Adhesin of Type 1 Fimbriae Is a Potent Inducer of Innate Antimicrobial Responses Which Requires TLR4 and Type 1 Interferon Signalling Journal Articles
Fish oil supplementation suppresses resistance exercise and feeding-induced increases in anabolic signaling without affecting myofibrillar protein synthesis in young men Journal Articles
Fisiopatologia do transtorno afetivo bipolar: o que mudou nos últimos 10 anos? Journal Articles
Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues Journal Articles
FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells Journal Articles
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells Journal Articles
Functional impact of global rare copy number variation in autism spectrum disorders Journal Articles
Functional linkage as a direction for studies in oxidative stress: α-adrenergic receptorsThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease. Journal Articles
Fundamentals of Neurogastroenterology: Basic Science Journal Articles
G Protein-coupled Receptor Kinase-mediated Desensitization of Metabotropic Glutamate Receptor 1A Protects against Cell Death Journal Articles
G-Protein–Coupled Receptors as Signaling Targets for Antiplatelet Therapy Journal Articles
GLP-1R Agonists Modulate Enteric Immune Responses Through the Intestinal Intraepithelial Lymphocyte GLP-1R Journal Articles
GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia Journal Articles
GTP and guanosine synergistically enhance NGF‐induced neurite outgrowth from PC12 cells Journal Articles
Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling Journal Articles
Genetic analysis of vein function in the Drosophila embryonic nervous system Journal Articles
Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model Journal Articles
Genome-wide comparisons of gene expression in adult versus elderly burn patients Journal Articles
Genome‐wide DNA methylation changes with age in disease‐free human skeletal muscle Journal Articles
Genomic Minimalism in the Early Diverging Intestinal Parasite Giardia lamblia Journal Articles
Genomic responses in mouse models poorly mimic human inflammatory diseases Journal Articles
Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma Journal Articles
Germline variation in the insulin-like growth factor pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma Journal Articles
Gli3-mediated hedgehog inhibition in human pluripotent stem cells initiates and augments developmental programming of adult hematopoiesis Journal Articles
Glucocortiosteroid subsensitivity and asthma severity Journal Articles
Glucose transporter expression in L6 muscle cells: Regulation through insulin- and stress-activated pathways Journal Articles
Glucose‐regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders Journal Articles
Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells. Journal Articles
Glycogen Synthase Kinase 3α Deficiency Attenuates Atherosclerosis and Hepatic Steatosis in High Fat Diet–Fed Low Density Lipoprotein Receptor–Deficient Mice Journal Articles
Glycosyltransferases and Glycosaminoglycans in Bleomycin and Transforming Growth Factor-β1–Induced Pulmonary Fibrosis Journal Articles
Glypican LON-2 Is a Conserved Negative Regulator of BMP-like Signaling in Caenorhabditis elegans Journal Articles
Grain‐sized moxibustion promotes NK cell antitumour immunity by inhibiting adrenergic signalling in non–small cell lung cancer Journal Articles
Green tea catechins evoke a phasic contraction in rat aorta via H₂O₂‐mediated multiple‐signalling pathways Journal Articles
Guanosine 5´-O-(3-Thiotriphosphate) and Cations Regulate Melatonin Receptors, and Melatonin Inhibits Cyclic AMP Production in the Spinal Cord Journal Articles
Guanosine Inhibits CD40 Receptor Expression and Function Induced by Cytokines and β Amyloid in Mouse Microglia Cells Journal Articles
Guanosine Protects Glial Cells Against 6-Hydroxydopamine Toxicity Journal Articles
Guanosine promotes proliferation of neural stem cells through cAMP-CREB pathway. Journal Articles
Guidance signalling regulates leading edge behaviour during collective cell migration of cardiac cells in Drosophila Journal Articles
Gut Microbiota and Brain Function: An Evolving Field in Neuroscience: Table 1. Journal Articles
Gut commensal microvesicles reproduce parent bacterial signals to host immune and enteric nervous systems Journal Articles
H9724, a monoclonal antibody to Borrelia burgdorferi's flagellin, binds to heat shock protein 60 (HSP60) within live neuroblastoma cells: a potential role for HSP60 in peptide hormone signaling and in an autoimmune pathogenesis of the neuropathy of Lyme disease. Journal Articles
HB-EGF release mediates glucose-induced activation of the epidermal growth factor receptor in mesangial cells Journal Articles
HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants Journal Articles
HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner Journal Articles
HIV-1 gp120 Induces TLR2- and TLR4-Mediated Innate Immune Activation in Human Female Genital Epithelium Journal Articles
HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells Journal Articles
HSP90 modulates actin dynamics: Inhibition of HSP90 leads to decreased cell motility and impairs invasion Journal Articles
HUMAN PLATELET THROMBIN RECEPTORS Journal Articles
Haemopoietic processes in allergic disease: eosinophil/basophil development Journal Articles
Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling Journal Articles
Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration Journal Articles
Hematopoietic stem cell biology: too much of a Wnt thing Journal Articles
Heparin Inhibits Melatonin Binding and Signal Transduction in Chick Brain Journal Articles
Heparin Synergistically Enhances Interleukin-11 Signaling through Up-regulation of the MAPK Pathway Journal Articles
Hepatic Glucose Intolerance Precedes Hepatic Steatosis in the Male Aromatase Knockout (ArKO) Mouse Journal Articles
Herpes Simplex Virus 1 Tegument Protein US11 Downmodulates the RLR Signaling Pathway via Direct Interaction with RIG-I and MDA-5 Journal Articles
Herpes Simplex Virus Triggers and Then Disarms a Host Antiviral Response Journal Articles
Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells Journal Articles
High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells Journal Articles
High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus Journal Articles
High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells Journal Articles
High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2 Journal Articles
Histamine activates Cl‐ and K+ currents in guinea‐pig tracheal myocytes: convergence with muscarinic signalling pathway. Journal Articles
Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy Journal Articles
History of bystander effects research 1905-present; what is in a name? Journal Articles
Host Defence Peptide LL-37 Induces IL-6 Expression in Human Bronchial Epithelial Cells by Activation of the NF-κB Signaling Pathway Journal Articles
Host Defense Peptide LL-37, in Synergy with Inflammatory Mediator IL-1β, Augments Immune Responses by Multiple Pathways Journal Articles
How Linear Tension Converts to Curvature: Geometric Control of Bone Tissue Growth Journal Articles
How is Mitochondrial Biogenesis Affected in Mitochondrial Disease? Journal Articles
Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia Journal Articles
Human Milk Oligosaccharides Protect against Necrotizing Enterocolitis by Activating Intestinal Cell Differentiation Journal Articles
Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells Journal Articles
Hydrogen peroxide is an endothelium‐dependent contracting factor in rat renal artery Journal Articles
Hydrogen sulfide in the pathogenesis of atherosclerosis and its therapeutic potential Journal Articles
Hydrogen sulfide is a regulator of mammary gland development in prepubescent female mice Journal Articles
Hydrogen sulfide is an endogenous stimulator of angiogenesis Journal Articles
Hydroxychloroquine attenuates cigarette smoke induced autophagic signaling in the mouse ovary Journal Articles
Hyperglycemia Exacerbates Burn-Induced Liver Inflammation via Noncanonical Nuclear Factor-κB Pathway Activation Journal Articles
Hyperinsulinemia-induced vascular smooth muscle cell (VSMC) migration and proliferation is mediated by converging mechanisms of mitochondrial dysfunction and oxidative stress Journal Articles
Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response Journal Articles
Hypoxia-Driven Immune Escape in the Tumor Microenvironment Journal Articles
Hypoxia-induced autophagy, epithelial to mesenchymal transition, and invasion in the pathophysiology of endometriosis: a perspective Journal Articles
Hypoxia-inducible factor-1α mediates the expression of mature β cell-disallowed genes in hypoxia-induced β cell dedifferentiation Journal Articles
ID4-dependent secretion of VEGFA enhances the invasion capability of breast cancer cells and activates YAP/TAZ via integrin β3-VEGFR2 interaction Journal Articles
IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity Journal Articles
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro Journal Articles
IGF-1 Protects Intestinal Epithelial Cells From Oxidative Stress-Induced Apoptosis Journal Articles
II. The intestine as a sensory organ: neural, endocrine, and immune responses Journal Articles
IL-15 Can Signal via IL-15Rα, JNK, and NF-κB To Drive RANTES Production by Myeloid Cells Journal Articles
IL-15 and Type I Interferon Are Required for Activation of Tumoricidal NK Cells by Virus-Infected Dendritic Cells Journal Articles
IL-15 has innate anti-tumor activity independent of NK and CD8 T cells Journal Articles
IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization Journal Articles
IL-4 and IL-13 Differentially Regulate TLR-Induced Eosinophil-Basophil Differentiation of Cord Blood CD34+ Progenitor Cells Journal Articles
IL-6 Induced STAT3 Signalling Is Associated with the Proliferation of Human Muscle Satellite Cells Following Acute Muscle Damage Journal Articles
IL‐25 promotes cisplatin resistance of lung cancer cells by activating NF‐κB signaling pathway to increase of major vault protein Journal Articles
Identification and Characterization of New Inhibitors of Fungal Homoserine Kinase Journal Articles
Identification of COUP-TFII as a peroxisome proliferator response element binding factor using genetic selection in yeast: COUP-TFII activates transcription in yeast but anatagonizes PPAR signaling in mammalian cells Journal Articles
Identification of Dp71 Isoforms in the Platelet Membrane Cytoskeleton Journal Articles
Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells Journal Articles
Identification of Synthetic Peptides that Inhibit Lipopolysaccharide (LPS) Binding to Myeloid Differentiation Protein-2 (MD-2) Journal Articles
Identification of a Novel Pathway Essential for the Immediate-Early, Interferon-Independent Antiviral Response to Enveloped Virions Journal Articles
Identification of periplakin as a major regulator of lung injury and repair in mice Journal Articles
IgA potentiates NETosis in response to viral infection Journal Articles
Immune Inhibitory Ligand CD200 Induction by TLRs and NLRs Limits Macrophage Activation to Protect the Host from Meningococcal Septicemia Journal Articles
Immunological Events Underlying the Induction of T Cell Non-Responsiveness Journal Articles
Immunometabolism of AMPK in insulin resistance and atherosclerosis Journal Articles
Immunometabolism of obesity and diabetes: microbiota link compartmentalized immunity in the gut to metabolic tissue inflammation Journal Articles
Immunosignatures associated with TP53 status and co-mutations classify prognostically head and neck cancer patients Journal Articles
Impact of the menstrual cycle on peripheral vascular function in premenopausal women: systematic review and meta-analysis Journal Articles
Impaired Epithelial CD200L Tolerance Signaling in Irritable Bowel Syndrome Cases With Diarrhea May Be Associated With Recurrent Miscarriages Journal Articles
Impaired Growth and Force Production in Skeletal Muscles of Young Partially Pancreatectomized Rats: A Model of Adolescent Type 1 Diabetic Myopathy? Journal Articles
Impaired c-src activation and motility defects in PEA3-null fibroblasts Journal Articles
Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis Journal Articles
Improving the Quality of Lung Cancer Care in Ontario: The Lung Cancer Disease Pathway Initiative Journal Articles
In Vitro Selection of Structure‐Switching Signaling Aptamers Journal Articles
Increased FGF8 signaling promotes chondrogenic rather than osteogenic development in the embryonic skull Journal Articles
Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes Journal Articles
Increased Placental Apoptosis in Maternal Food Restricted Gestations: Role of the Fas Pathway Journal Articles
Increased proliferation of hepatic periportal ductal progenitor cells contributes to persistent hypermetabolism after trauma Journal Articles
Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling Journal Articles
Induction of interleukin‐10 and suppressor of cytokine signalling‐3 gene expression following peptide immunotherapy Journal Articles
Inflammasomes in the lung Journal Articles
Inflammation in Obesity is a Common Link Between Defects in Fatty Acid Metabolism and Insulin Resistance Journal Articles
Inflammation promotes adipocyte lipolysis via IRE1 kinase Journal Articles
Inflammation, depression and cardiovascular disease in women: the role of the immune system across critical reproductive events Journal Articles
Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection Journal Articles
Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Journal Articles
Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin Journal Articles
Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice Journal Articles
Inhibition of endogenous MTF-1 signaling in zebrafish embryos identifies novel roles for MTF-1 in development Journal Articles
Inhibition of sporulation, glycopeptide antibiotic production and resistance in Streptomyces toyocaensis NRRL 15009 by protein kinase inhibitors Journal Articles
Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin Journal Articles
Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain Journal Articles
Innate Immune Cytokines, Fibroblast Phenotypes, and Regulation of Extracellular Matrix in Lung Journal Articles
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism Journal Articles
Innate and adaptive immunity against herpes simplex virus type 2 in the genital mucosa Journal Articles
Insulin Activates a p21-activated Kinase in Muscle Cells via Phosphatidylinositol 3-Kinase Journal Articles
Insulin Attenuates Apoptosis and Exerts Anti-Inflammatory Effects in Endotoxemic Human Macrophages Journal Articles
Insulin Attenuates the Systemic Inflammatory Response in Endotoxemic Rats Journal Articles
Insulin Decreases Inflammatory Signal Transcription Factor Expression in Primary Human Liver Cells after LPS Challenge Journal Articles
Insulin signaling and limb-patterning: candidate pathways for the origin and evolutionary diversification of beetle ‘horns’ Journal Articles
Insulin signalling in mushroom body neurons regulates feeding behaviour inDrosophilalarvae Journal Articles
Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1 Journal Articles
Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response Journal Articles
Integrins Regulate Responsiveness to Slit Repellent Signals Journal Articles
Integrins are required for cardioblast polarisation in Drosophila Journal Articles
Interaction of Peptide Substrates of Fibroblast Collagenase with Divalent Cations: Ca2+ Binding by Substrate as a Suggested Recognition Signal for Collagenase Action Journal Articles
Interaction of c-Abl and p73α and their collaboration to induce apoptosis Journal Articles
Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction Journal Articles
Interferon Gamma in Successful Pregnancies1 Journal Articles
Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function Journal Articles
Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair Journal Articles
Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase Journal Articles
Interleukins 4 and 13 Increase Intestinal Epithelial Permeability by a Phosphatidylinositol 3-Kinase Pathway Journal Articles
Interplay of the Peroxisome Proliferator‐activated Receptor and the Thyroid Hormone Receptor‐signaling Pathways in Regulating Peroxisome Proliferator–responsive Genes^a Journal Articles
Intracellular Trafficking of CD23: Differential Regulation in Humans and Mice by Both Extracellular and Intracellular Exons Journal Articles
Intracellular signalling by nucleotide receptors in PC12 pheochromocytoma cells Journal Articles
Intrinsic pathway of apoptosis in peripheral blood eosinophils of Churg–Strauss syndrome Journal Articles
Investigation of FGFR2-IIIC Signaling via FGF-2 Ligand for Advancing GCT Stromal Cell Differentiation Journal Articles
Investigations of the signaling cascade involved in diuretic hormone stimulation of Malpighian tubule fluid secretion in Rhodnius prolixus Journal Articles
Involvement of astrocytes in purine‐mediated reparative processes in the brain Journal Articles
Involvement of multiple sulfhydryl groups in melatonin signal transduction in chick brain Journal Articles
Involvement of the actin network in insulin signalling. Conferences
Ionic mechanisms and Ca2+ handling in airway smooth muscle Journal Articles
Ionic mechanisms and Ca²⁺regulation in airway smooth muscle contraction: do the data contradict dogma? Journal Articles
Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells Journal Articles
Ionotropic Receptors in Pulmonary Neuroepithelial Bodies (NEB) and their Possible Role in Modulation of Hypoxia Signalling Journal Articles
Is there convergence in the molecular pathways underlying the repeated evolution of sociality in African cichlids? Journal Articles
Is there potential for estradiol receptor signaling in lophotrochozoans? Journal Articles
Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca²⁺ handling and Rho/ROCK signaling Journal Articles
Isoprostanes and Lung Vascular Pathology Journal Articles
Isoprostanes constrict human radial artery by stimulation of thromboxane receptors, Ca2+ release, and RhoA activation Journal Articles
It’s Not Easy Being Blue: Are There Olfactory and Visual Trade-Offs in Plant Signalling? Journal Articles
Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells Journal Articles
Jnk1 activity lowers the cellular production of H2O2 and modulates the growth arrest response to scavenging of H2O2 by catalase Journal Articles
JunD/AP-1 Antagonizes the Induction of DAPK1 To Promote the Survival of v-Src-Transformed Cells Journal Articles
Just-in-time transcription program in metabolic pathways Journal Articles
Kaiso Represses the Cell Cycle Gene cyclin D1 via Sequence-Specific and Methyl-CpG-Dependent Mechanisms Journal Articles
Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells Journal Articles
Ketamine-induced neurotoxicity is mediated through endoplasmic reticulum stress in vitro in STHdhQ7/Q7 cells Journal Articles
Kinase-specific responsiveness to incremental contractile activity in skeletal muscle with low and high mitochondrial content Journal Articles
Leptin Therapy Reverses Hyperglycemia in Mice With Streptozotocin-Induced Diabetes, Independent of Hepatic Leptin Signaling Journal Articles
Leucine supplementation is anti-atrophic during paradoxical sleep deprivation in rats Journal Articles
Leukemia inhibitory factor increases glucose uptake in mouse skeletal muscle Journal Articles
Leukotriene D₄ receptors are not negatively coupled to adenylyl cyclase in guinea‐pig lung parenchyma Journal Articles
Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women Journal Articles
Lipogenesis inhibitors: therapeutic opportunities and challenges Journal Articles
Liraglutide Protects Pancreatic Islet From Ischemic Injury by Reducing Oxidative Stress and Activating Akt Signaling During Cold Preservation to Improve Islet Transplantation Outcomes Journal Articles
Local Regulation of Thyroid Hormone Signaling Chapters
Long Double-Stranded RNA Induces an Antiviral Response Independent of IFN Regulatory Factor 3, IFN-β Promoter Stimulator 1, and IFN Journal Articles
Looks Who’s Talking Now Journal Articles
Loss of Hepatocyte-Nuclear-Factor-1α Impacts on Adult Mouse Intestinal Epithelial Cell Growth and Cell Lineages Differentiation Journal Articles
Loss of dystrophin expression in skeletal muscle is associated with senescence of macrophages and endothelial cells Journal Articles
Low Density Lipoprotein Receptor-Related Protein-2 Expression in Efferent Duct and Epididymal Epithelia: Evidence in Rats for its in Vivo Role in Endocytosis of Apolipoprotein J/Clusterin1 Journal Articles
Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men Journal Articles
Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer Journal Articles
Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis Journal Articles
Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) Journal Articles
Lysophosphatidic acid receptor 1 inhibition: a potential treatment target for pulmonary fibrosis Journal Articles
Lysosomal and Proteasomal Degradation Play Distinct Roles in the Life Cycle of Cx43 in Gap Junctional Intercellular Communication-deficient and -competent Breast Tumor Cells Journal Articles
MAPping the kinase landscape of macrophage activation Journal Articles
MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial Trehalose Dimycolate and Mycobacterium tuberculosis Journal Articles
MD‐1 is a Critical Part of the Mechanism Causing Th1‐Cytokine‐Triggered Murine Fetal Loss Syndrome Journal Articles
Macrophages Regulate Unilateral Ureteral Obstruction-Induced Renal Lymphangiogenesis through C-C Motif Chemokine Receptor 2–Dependent Phosphatidylinositol 3-Kinase-AKT–Mechanistic Target of Rapamycin Signaling and Hypoxia-Inducible Factor-1α/Vascular Endothelial Growth Factor-C Expression Journal Articles
Magnolol inhibits venous remodeling in mice Journal Articles
Mammary glands exhibit molecular laterality and undergo left–right asymmetric ductal epithelial growth in MMTV-cNeu mice* Journal Articles
Maternal Nicotine Exposure Leads to Impaired Disulfide Bond Formation and Augmented Endoplasmic Reticulum Stress in the Rat Placenta Journal Articles
Maternal nutrient restriction impairs young adult offspring ovarian signaling resulting in reproductive dysfunction and follicle loss† Journal Articles
Mathematical model for chemotherapeutic drug efficacy in arresting tumour growth based on the cancer stem cell hypothesis Journal Articles
Mathematical model for the cancer stem cell hypothesis Journal Articles
Mathematical model of the role of intercellular signalling in intercellular cooperation during tumorigenesis Journal Articles
Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis Journal Articles
Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer. Journal Articles
Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through β-catenin signaling Journal Articles
Matters of taste: bridging molecular physiology and the humanities Journal Articles
Mechanical Strain-Induced RhoA Activation Requires NADPH Oxidase-Mediated ROS Generation in Caveolae Journal Articles
Mechanical Stretch-Induced Signal Transduction in Cultured Mesangial Cells Journal Articles
Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis Conferences
Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK Journal Articles
Mechanisms Employed by Herpes Simplex Virus 1 to Inhibit the Interferon Response Journal Articles
Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma Journal Articles
Mechanisms associated with mitochondrial-generated reactive oxygen species in cancerThis article is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease. Journal Articles
Mechanisms of Cardiovascular Toxicity of BCR-ABL1 Tyrosine Kinase Inhibitors in Chronic Myelogenous Leukemia Journal Articles
Mechanisms of exercise‐induced survival motor neuron expression in the skeletal muscle of spinal muscular atrophy‐like mice Journal Articles
Mechanisms of innate immune activation by gluten peptide p31-43 in mice Journal Articles
Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions Journal Articles
Medulloblastoma stem cells: Modeling tumor heterogeneity Journal Articles
Medulloblastoma stem cells: where development and cancer cross pathways Journal Articles
Melatonin and Hippo Pathway: Is There Existing Cross-Talk? Journal Articles
Melatonin—A pleiotropic, orchestrating regulator molecule Journal Articles
Mesangial cell signaling cascades in response to mechanical strain and glucose Journal Articles
Metabolic Syndrome and Acute Hyperglycemia Are Associated With Endoplasmic Reticulum Stress in Human Mononuclear Cells Journal Articles
Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment Journal Articles
Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC Journal Articles
Metformin: Metabolic Rewiring Faces Tumor Heterogeneity Journal Articles
Methylation-dependent regulation of hypoxia inducible factor-1 alpha gene expression by the transcription factor Kaiso Journal Articles
Mice with a Targeted Mutation of Patched2 Are Viable but Develop Alopecia and Epidermal Hyperplasia Journal Articles
MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity Journal Articles
MicroRNAs as Key Effectors in the p53 Network Journal Articles
MicroRNAs: Non-coding fine tuners of receptor tyrosine kinase signalling in cancer Journal Articles
Microvesicles Contribute to the Bystander Effect of DNA Damage Journal Articles
Mind the gap: Signal movement through plasmodesmata is critical for the manifestation of SAR Journal Articles
Mitochondrial Proteins at Unexpected Cellular Locations: Export of Proteins from Mitochondria from an Evolutionary Perspective Journal Articles
Mitochondrial contributions to cancer cell physiology: potential for drug development Journal Articles
Mitochondrial dysfunction is associated with a pro-apoptotic cellular environment in senescent cardiac muscle Journal Articles
Modelling the MYC-driven normal-to-tumour switch in breast cancer. Journal Articles
Modifying the Organ Matrix Pre-engraftment: A New Transplant Paradigm? Journal Articles
Modular pharmacology-based approach to identify hub genes and kernel pathways of taodan granules treated psoriasis Journal Articles
Modularity of protein function: Chimeric interleukin 1.beta.s containing specific protease inhibitor loops retain function of both molecules Journal Articles
Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication Journal Articles
Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis Journal Articles
Modulation of Hepatic Granulomatous Responses by Transgene Expression of DAP12 or TREM-1-Ig Molecules Journal Articles
Modulation of Human Airway Smooth Muscle Migration by Lipid Mediators and Th-2 Cytokines Journal Articles
Modulation of autophagy signaling with resistance exercise and protein ingestion following short-term energy deficit Journal Articles
Modulation of insulin action by vanadate: evidence of a role for phosphotyrosine phosphatase activity to alter cellular signaling Journal Articles
Modulation of oxidative phosphorylation (OXPHOS) by radiation- induced biophotons Journal Articles
Molecular Genetic Analysis of the Idd4 Locus Implicates the IFN Response in Type 1 Diabetes Susceptibility in Nonobese Diabetic Mice Journal Articles
Molecular Mechanisms Linking Diabetes to the Accelerated Development of Atherosclerosis Journal Articles
Molecular Pathways: Epigenetic Modulation of Wnt–Glycogen Synthase Kinase-3 Signaling to Target Human Cancer Stem Cells Journal Articles
Molecular Pathways: Leveraging the BCL-2 Interactome to Kill Cancer Cells—Mitochondrial Outer Membrane Permeabilization and Beyond Journal Articles
Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States Journal Articles
Molecular and Histological Analysis of a New Rat Model of Experimental Knee Osteoarthritis Conferences
Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice Journal Articles
Molecular signatures in rainbow darter (Etheostoma caeruleum) inhabiting an urbanized river reach receiving wastewater effluents Journal Articles
Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis Journal Articles
Molecules in focus Transforming growth factor-beta (TGF-β) Journal Articles
Monocytic Differentiation of Acute Promyelocytic Leukemia Cells in Response to 1,25-Dihydroxyvitamin D3 Is Independent of Nuclear Receptor Binding Journal Articles
Mood and gut feelings Journal Articles
Multifactorial Regulation of Prostaglandin Synthesis in Preovulatory Goldfish Ovarian Follicles1 Journal Articles
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset Journal Articles
Multiple Signaling Pathways Control the Activation of the CEF-4/9E3 Cytokine Gene by pp60v- Journal Articles
Multiple histidines in the periplasmic domain of the Salmonella enterica sensor kinase SsrA enhance signaling in response to extracellular acidification Journal Articles
Multitargeted anti-angiogenic agents and NSCLC: Clinical update and future directions Journal Articles
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells Journal Articles
Muscarinic acetylcholine receptor activation increases transcellular transport of macromolecules across mouse and human intestinal epithelium in vitro Journal Articles
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition Journal Articles
Mutations in Caenorhabditis briggsae identify new genes important for limiting the response to EGF signaling during vulval development Journal Articles
Mutations in TBCK, Encoding TBC1-Domain-Containing Kinase, Lead to a Recognizable Syndrome of Intellectual Disability and Hypotonia Journal Articles
Myelin-Associated Glycoprotein Is a Myelin Signal that Modulates the Caliber of Myelinated Axons Journal Articles
Myostatin inhibition therapy for insulin-deficient type 1 diabetes Journal Articles
Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts Journal Articles
N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation Journal Articles
NOD1 Activators Link Innate Immunity to Insulin Resistance Journal Articles
NRAGE, A Novel MAGE Protein, Interacts with the p75 Neurotrophin Receptor and Facilitates Nerve Growth Factor–Dependent Apoptosis Journal Articles
NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway Journal Articles
Naphthenic Acid Mixtures from Oil Sands Process-Affected Water Enhance Differentiation of Mouse Embryonic Stem Cells and Affect Development of the Heart Journal Articles
Natural products for the treatment of neurodegenerative diseases Journal Articles
Nerve growth factor treatment alters Ca2+ pump levels in PC12 cells Journal Articles
Neuroimmunologic and Neurotrophic Interactions in Autism Spectrum Disorders: Relationship to Neuroinflammation Journal Articles
Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line Journal Articles
Neutralization of LPS or blockage of TLR4 signaling prevents stress-triggered fetal loss in murine pregnancy Journal Articles
Neutrons do not produce a bystander effect in zebrafish irradiated in vivo Journal Articles
New therapeutic strategies to treat human cancers expressing mutant p53 proteins Journal Articles
New treatment and markers of prognosis for idiopathic pulmonary fibrosis: lessons learned from translational research Journal Articles
Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells Journal Articles
Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells Journal Articles
Nitric oxide, human diseases and the herbal products that affect the nitric oxide signalling pathway Journal Articles
Nitric oxide-dependent changes in Schistosoma mansoni gene expression Journal Articles
Non-Canonical Allostery in Cyclic Nucleotide Dependent Kinases Journal Articles
Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin Journal Articles
Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota Journal Articles
Non-ionotropic voltage-gated calcium channel signaling Journal Articles
Noncanonical Wnt Signaling Orchestrates Early Developmental Events toward Hematopoietic Cell Fate from Human Embryonic Stem Cells Journal Articles
Nonendothelial Aortic Source of Nitric Oxide in Wistar-Kyoto Normotensive and Spontaneous Hypertensive Rats Journal Articles
Nonhematopoietic cells represent a more rational target of in vivo hedgehog signaling affecting normal or acute myeloid leukemia progenitors Journal Articles
Normal and defective pathways in biogenesis and maintenance of the insulin storage pool Journal Articles
Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma Journal Articles
Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells Journal Articles
Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells Journal Articles
Notch-Induced miR-708 Antagonizes Satellite Cell Migration and Maintains Quiescence Journal Articles
Novel 5-HT₇ receptor antagonists modulate intestinal immune responses and reduce severity of colitis Journal Articles
Novel paradigms of innate immune sensing of viral infections Journal Articles
Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells Journal Articles
Nuclear import of the BTB/POZ transcriptional regulator Kaiso Journal Articles
Nutrient Sensing and Response Drive Developmental Progression in Caenorhabditis elegans Journal Articles
Nutrient provision increases signalling and protein synthesis in human skeletal muscle after repeated sprints Journal Articles
O-GlcNAc-glycosylation of β-catenin regulates its nuclear localization and transcriptional activity Journal Articles
ORIGINAL ARTICLE: LPS‐Induced Murine Abortions Require C5 but not C3, and are Prevented by Upregulating Expression of the CD200 Tolerance Signaling Molecule Journal Articles
Obstacles to effective Toll-like receptor agonist therapy for hematologic malignancies Journal Articles
Oncogenes belonging to the CSF-1 transduction pathway direct p53 tumor suppressor effects to monocytic differentiation in 32D cells Journal Articles
Oncolytic bovine herpesvirus type 1 infects and kills breast tumor cells and breast cancer-initiating cells irrespective of tumor subtype Journal Articles
Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: Regulation of the type-II IL-4 receptor chains IL-4Rα and IL-13Rα1 Journal Articles
Oncostatin M Regulates Eotaxin Expression in Fibroblasts and Eosinophilic Inflammation in C57BL/6 Mice Journal Articles
Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells Journal Articles
Oncostatin M induction of eotaxin-1 expression requires the convergence of PI3′K and ERK1/2 MAPK signal transduction pathways Journal Articles
Oncostatin M-Induced IL-6 Expression in Murine Fibroblasts Requires the Activation of Protein Kinase Cδ Journal Articles
Ontogeny of O2 and CO2//H+ chemosensitivity in adrenal chromaffin cells: role of innervation Journal Articles
Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma Journal Articles
Opposing effects of IL-1β/COX-2/PGE2 pathway loop on islets in type 2 diabetes mellitus Journal Articles
Overexpression of the Endoplasmic Reticulum 60 Protein ER-60 Downregulates ApoB100 Secretion by Inducing Its Intracellular Degradation via a Nonproteasomal Pathway: Evidence for an ER-60-Mediated and pCMB-Sensitive Intracellular Degradative Pathway Journal Articles
Oxidative stress and Nrf2 signaling in McArdle disease Journal Articles
Oxygen sensing in airway chemoreceptors Journal Articles
Oxytocin down‐regulates mesenteric afferent sensitivity via the enteric OTR/nNOS/NO/K_ATP pathway in rat Journal Articles
Oxytocin hyperpolarizes cultured duodenum myenteric intrinsic primary afferent neurons by opening BK_Ca channels through IP₃ pathway Journal Articles
P2Y₂ Receptor Up-Regulation Induced by Guanosine or UTP in Rat Brain Cultured Astrocytes Journal Articles
PDZK1 in leukocytes protects against cellular apoptosis and necrotic core development in atherosclerotic plaques in high fat diet fed ldl receptor deficient mice Journal Articles
PIKfyve: a new fish in the growing pool of AMPK substrates Journal Articles
PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells Journal Articles
POST-BURN HEPATIC INSULIN RESISTANCE IS ASSOCIATED WITH ENDOPLASMIC RETICULUM (ER) STRESS Journal Articles
PPAR ligands decrease human airway smooth muscle cell migration and extracellular matrix synthesis Journal Articles
PRY-1/Axin signaling regulates lipid metabolism in Caenorhabditis elegans Journal Articles
Packing on the Pounds in Response to Bacterial Growth Conditions Journal Articles
Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans Journal Articles
Palmitate differentially regulates the polarization of differentiating and differentiated macrophages Journal Articles
Pan-urologic cancer genomic subtypes that transcend tissue of origin Journal Articles
Panax notoginseng saponin is superior to aspirin in inhibiting platelet adhesion to injured endothelial cells through COX pathway in vitro Journal Articles
Panax quinquefolium saponin combined with dual antiplatelet drugs inhibits platelet adhesion to injured HUVECs via PI3K/AKT and COX pathways Journal Articles
Parallel multi-time point cell stimulation and lysis on-chip for studying early signaling events in T cell activation Journal Articles
Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Signaling Journal Articles
Pathway Pathology Journal Articles
Pea3 Transcription Factors and Wnt1-Induced Mouse Mammary Neoplasia Journal Articles
Peptide hormones, neurotransmitters, and drugs as Ca²⁺ ionophores: implications for signal transduction Journal Articles
Perinatal Administration of a Selective Serotonin Reuptake Inhibitor Induces Impairments in Reproductive Function and Follicular Dynamics in Female Rat Offspring Journal Articles
Peripheral Blood Gene Expression Changes during Allergen Inhalation Challenge in Atopic Asthmatic Individuals Journal Articles
Perturbations to Homeostasis in Experimental Models Revealed Innate Pathways Driving Food Allergy Journal Articles
Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer Journal Articles
Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional Activity Journal Articles
Placental Trophoblast from Successful Human Pregnancies Expresses the Tolerance Signaling Molecule, CD200 (OX‐2)* Journal Articles
Plasma Proteome Response to Severe Burn Injury Revealed by ¹⁸O-Labeled “Universal” Reference-Based Quantitative Proteomics Journal Articles
Plasminogen Alleles Influence Susceptibility to Invasive Aspergillosis Journal Articles
Plasticity of Skeletal Muscle Mitochondria in Response to Contractile Activity Journal Articles
Pleiotropic actions of factor Xa inhibition in cardiovascular prevention: mechanistic insights and implications for anti-thrombotic treatment Journal Articles
Pleiotropic roles of Notch signaling in normal, malignant, and developmental hematopoiesis in the human Journal Articles
Poly ADP-ribose signaling is dysregulated in Huntington disease. Journal Articles
Polymorphism in the Innate Immune Receptor SIRPα Controls CD47 Binding and Autoimmunity in the Nonobese Diabetic Mouse Journal Articles
Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis Journal Articles
Prolonged moderate-intensity aerobic exercise does not alter apoptotic signaling and DNA fragmentation in human skeletal muscle Journal Articles
Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation Journal Articles
Propranolol Improves Impaired Hepatic Phosphatidylinositol 3-Kinase/Akt Signaling after Burn Injury Journal Articles
Protean effects of a natural peptide agonist of the G protein-coupled secretin receptor demonstrated by receptor mutagenesis. Journal Articles
Protective activity of guanosine in an in vitro model of Parkinson's disease. Journal Articles
Protein Ingestion Increases Myofibrillar Protein Synthesis after Concurrent Exercise Journal Articles
Protein arginine methyltransferase expression, localization, and activity during disuse-induced skeletal muscle plasticity Journal Articles
Protein kinase C α modulates liver X receptor α transactivation Journal Articles
Protein kinase CK1alphaLS promotes vascular cell proliferation and intimal hyperplasia. Journal Articles
Protein kinase Cα negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor Journal Articles
Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation Journal Articles
Proteomic changes in the gills of wild-type and transgenic radiosensitive medaka following exposure to direct irradiation and to X-ray induced bystander signals Journal Articles
Proximal Gut Mucosal Epithelial Homeostasis in Aged IL-1 Type I Receptor Knockout Mice after Starvation Journal Articles
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways Journal Articles
Psychosis pathways converge via D2High dopamine receptors Journal Articles
Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells Journal Articles
Purification and characterization of VanR and the cytosolic domain of VanS: A two-component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147 Journal Articles
Purine and pyrimidine nucleotides activate distinct signalling pathways in PC12 cells Journal Articles
Purinergic Pathways in the Spinal Microglia as a Putative Target for Treatment of Chronic Abdominal Pain Journal Articles
Purinergic Signalling Mediates Aberrant Excitability of Developing Neuronal Circuits in the Fmr1 Knockout Mouse Model Journal Articles
Pyruvate Is Synthesized by Two Pathways in Pea Bacteroids with Different Efficiencies for Nitrogen Fixation Journal Articles
Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells Journal Articles
Quantum Biology and the Potential Role of Entanglement and Tunneling in Non-Targeted Effects of Ionizing Radiation: A Review and Proposed Model Journal Articles
Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production Journal Articles
Quorum sensing in Escherichia coli and Salmonella typhimurium Journal Articles
RIPK2 Dictates Insulin Responses to Tyrosine Kinase Inhibitors in Obese Male Mice Journal Articles
Radiation and the regulatory landscape of neo2-Darwinism Journal Articles
Radiation-Induced Bystander and other Non-Targeted Effects: Novel Intervention Points in Cancer Therapy? Journal Articles
Radiation-induced bystander effects — implications for cancer Journal Articles
Radiosensitization of glioma cells by modulation of Met signalling with the hepatocyte growth factor neutralizing antibody, AMG102 Journal Articles
Radiotherapy and the potential exploitation of bystander effects Journal Articles
Rapamycin does not prevent increases in myofibrillar or mitochondrial protein synthesis following endurance exercise Journal Articles
Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insulin Signaling Journal Articles
Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise Journal Articles
Rapid stimulation of glucose transport by mitochondrial uncoupling depends in part on cytosolic Ca²⁺ and cPKC Journal Articles
Reactive oxygen species from mitochondria impacts trophoblast fusion and the production of endocrine hormones by syncytiotrophoblasts Journal Articles
Recent advances in understanding viral evasion of type I interferon Journal Articles
Recent insights into neuromuscular junction biology in Duchenne muscular dystrophy: Impacts, challenges, and opportunities Journal Articles
Receptor Subunit-specific Action of Oncostatin M in Hepatic Cells and Its Modulation by Leukemia Inhibitory Factor Journal Articles
Receptor domains of two-component signal transduction systems Journal Articles
Receptor-interacting protein 140 interacts with and inhibits transactivation by, peroxisome proliferator-activated receptor α and liver-X-receptor α Journal Articles
Receptor-mediated protein kinase activation and the mechanism of transmembrane signaling in bacterial chemotaxis Journal Articles
Receptors and signaling pathway underlying relaxations to isoprostanes in canine and porcine airway smooth muscle Journal Articles
Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity Journal Articles
Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression Journal Articles
Reduced carbohydrate availability enhances exercise-induced p53 signaling in human skeletal muscle: implications for mitochondrial biogenesis Journal Articles
Regulation of Acidification and Apoptosis by SHP-1 and Bcl-2 Journal Articles
Regulation of Eosinophilia in Asthma—New Therapeutic Approaches for Asthma Treatment Journal Articles
Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M Journal Articles
Regulation of Mitochondrial Biogenesis in Muscle by Endurance Exercise Journal Articles
Regulation of Myogenic Differentiation by Androgens: Cross Talk between Androgen Receptor/ β-Catenin and Follistatin/Transforming Growth Factor-β Signaling Pathways Journal Articles
Regulation of Rho/ROCK signaling in airway smooth muscle by membrane potential and [Ca²⁺]_i Journal Articles
Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways Journal Articles
Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain Journal Articles
Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3 Journal Articles
Regulation of a muralytic enzyme-encoding gene by two non-coding RNAs Journal Articles
Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli Journal Articles
Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli. Journal Articles
Regulation of gene expression in oncogenically transformed cells Journal Articles
Regulation of glucose transporter 4 traffic by energy deprivation from mitochondrial compromise Journal Articles
Regulation of plasminogen activator inhibitor-1 secretion by growth factors in smooth muscle cells Journal Articles
Regulation of plasminogen activator inhibitor‐1 secretion by urokinase and tissue plasminogen activator in rat epithelioid‐type smooth muscle cells Journal Articles
Regulation of signal transducer, gp130 and the lif receptor in acute inflammation in vivo Journal Articles
Regulation of slow wave frequency by IP₃-sensitive calcium release in the murine small intestine Journal Articles
Regulation of the proline regulatory axis and autophagy modulates stemness in TP73/p73 deficient cancer stem-like cells Journal Articles
Regulation of the water channel aquaporin‐1: isolation and reconstitution of the regulatory complex Journal Articles
Regulatory properties of neuronal cdc2-like kinase Journal Articles
Relaxin alters cardiac myofilament function through a PKC-dependent pathway Journal Articles
Release of Neutrophil Extracellular Traps by Neutrophils Stimulated With Antiphospholipid Antibodies: A Newly Identified Mechanism of Thrombosis in the Antiphospholipid Syndrome Journal Articles
Repellent Signaling by Slit Requires the Leucine-Rich Repeats Journal Articles
Reply to The Letter to The Editor: Adipocyte Browning in Response to Trauma: Some Important Methodological Considerations Journal Articles
Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis Journal Articles
Resistance exercise decreases eIF2Bε phosphorylation and potentiates the feeding-induced stimulation of p70^S6K1 and rpS6 in young men Journal Articles
Resistance exercise enhances mTOR and MAPK signalling in human muscle over that seen at rest after bolus protein ingestion Journal Articles
Resistance exercise load does not determine training-mediated hypertrophic gains in young men Journal Articles
Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men Journal Articles
Resistance exercise‐induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men Journal Articles
Resistance training minimizes catabolic effects induced by sleep deprivation in rats Journal Articles
Response regulator output in bacterial chemotaxis Journal Articles
Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis Journal Articles
Revisiting Type 2‐high and Type 2‐low airway inflammation in asthma: current knowledge and therapeutic implications Journal Articles
Rocaglamide promotes the infiltration and antitumor immunity of NK cells by activating cGAS-STING signaling in non-small cell lung cancer Journal Articles
Role of DAP12 in Innate and Adaptive Immune Responses Journal Articles
Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC) Journal Articles
Role of Ets transcription factors in mammary gland development and oncogenesis. Journal Articles
Role of Hippo pathway dysregulation from gastrointestinal premalignant lesions to cancer Journal Articles
Role of Sarcoplasmic Reticulum in the Contractile Function of Vascular Smooth Muscle as Studied by 2,5-Di-(Tert-Butyl)-1,4-Benzohydroquinone Journal Articles
Role of Serum Amyloid A as an Intermediate in the IL-1 and PMA-Stimulated Signaling Pathways Regulating Expression of Rabbit Fibroblast Collagenase Journal Articles
Role of bisphenol A on calcium influx and its potential toxicity on the testis of Danio rerio Journal Articles
Role of serotonergic neurons in the Drosophila larval response to light Journal Articles
Role of the COX2-PGE₂ axis in S. pneumoniae-induced exacerbation of experimental fibrosis Journal Articles
Role of the actin cytoskeleton in insulin action Journal Articles
Role of α-Helical Coiled-coil Interactions in Receptor Dimerization, Signaling, and Adaptation during Bacterial Chemotaxis Journal Articles
Roles for VEGF‐C/NRP–2 axis in regulating renal tubular epithelial cell survival and autophagy during serum deprivation Journal Articles
SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells Journal Articles
SBDS-deficient cells undergo accelerated apoptosis through the Fas-pathway Journal Articles
SHC-3: a previously unidentified C. elegans Shc family member functions in the insulin-like signaling pathway to enhance survival during L1 arrest Journal Articles
SMAD3-dependent and -independent pathways in glomerular injury associated with experimental glomerulonephritis Journal Articles
SNORD90 induces glutamatergic signaling following treatment with monoaminergic antidepressants Journal Articles
SOX2 Functions to Maintain Neural Progenitor Identity Journal Articles
SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells Journal Articles
SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction Journal Articles
SREBP-1 activation by glucose mediates TGF-β upregulation in mesangial cells Journal Articles
SREBP-1 is a novel mediator of TGFβ1 signaling in mesangial cells Journal Articles
STAT-6 Is an Absolute Requirement for Murine Rejection of Hymenolepis diminuta Journal Articles
Saikosaponin d downregulates microRNA-155 and upregulates FGF2 to improve depression-like behaviors in rats induced by unpredictable chronic mild stress by negatively regulating NF-κB Journal Articles
Salicylate enhances the response of prostate cancer to radiotherapy Journal Articles
Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine Journal Articles
SapB and the chaplins: connections between morphogenetic proteins in Streptomyces coelicolor Journal Articles
Scar management in burn injuries using drug delivery and molecular signaling: Current treatments and future directions Journal Articles
Selective involvement of the PI3K/PKB/bad pathway in retinal cell death Journal Articles
Selenite Inhibits the c-Jun N-terminal Kinase/Stress-activated Protein Kinase (JNK/SAPK) through a Thiol Redox Mechanism Journal Articles
Semaphorin 3F Antagonizes Neurotrophin-Induced Phosphatidylinositol 3-Kinase and Mitogen-Activated Protein Kinase Kinase Signaling: A Mechanism for Growth Cone Collapse Journal Articles
Sensitization of G Protein‐Coupled Benzodiazepine Receptors in the Striatum of 6‐Hydroxydopamine‐Lesioned Rats Journal Articles
Separate roles of IL‐6 and oncostatin M in mouse macrophage polarization in vitro and in vivo Journal Articles
Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts Journal Articles
Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells Journal Articles
Shear flow-induced motility ofDictyostelium discoideumcells on solid substrate Journal Articles
Shifting of Immune Responsiveness to House Dust Mite by Influenza A Infection: Genomic Insights Journal Articles
Signal Transduction Pathways Involved in EnterohemorrhagicEscherichia coli-Induced Alterations in T84 Epithelial Permeability Journal Articles
Signal Transduction within G-protein Coupled Receptors via an Ion Tunnel: A Hypothesis Journal Articles
Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects Journal Articles
Signal pathways involved in microbe–nematode interactions provide new insights into the biocontrol of plant-parasitic nematodes Journal Articles
Signal processing at mammalian carotid body chemoreceptors Journal Articles
Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells Journal Articles
Signal transduction in bacterial chemotaxis. Journal Articles
Signal transduction in smooth muscle as studied by the subcellular membrane approach Journal Articles
Signaling at Crossroads: The Dialogue between PDEs and PKA is Spoken in Multiple Languages Journal Articles
Signaling at the Fetomaternal Interface Journal Articles
Signaling through dynamic linkers as revealed by PKA Journal Articles
Simple Fluorescent Sensors Engineered with Catalytic DNA ‘MgZ’ Based on a Non-Classic Allosteric Design Journal Articles
Sirolimus and mTORC1: centre stage in the story of what makes muscles bigger? Journal Articles
Skeletal Muscle Lipogenic Protein Expression Is Not Different between Lean and Obese Individuals: A Potential Factor in Ceramide Accumulation Journal Articles
Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK Journal Articles
Skeletal muscle myoblasts possess a stretch-responsive local angiotensin signalling system Journal Articles
Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis Journal Articles
Smad3 Signaling Involved in Pulmonary Fibrosis and Emphysema Journal Articles
Smad3-dependent and -independent pathways are involved in peritoneal membrane injury Journal Articles
Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling Journal Articles
Socs1 Deficiency Enhances Hepatic Insulin Signaling Journal Articles
Sox9-related signaling controls zebrafish juvenile ovary–testis transformation Journal Articles
Spatial Fold Change of FGF Signaling Encodes Positional Information for Segmental Determination in Zebrafish. Journal Articles
Spatiotemporal encoding of sound level: Models for normal encoding and recruitment of loudness Journal Articles
Specialized and shared functions of diguanylate cyclases and phosphodiesterases in Streptomyces development Journal Articles
Specific CD45 isoforms differentially regulate T cell receptor signaling. Journal Articles
Sphingosine-1-Phosphate Receptor 1, Expressed in Myeloid Cells, Slows Diet-Induced Atherosclerosis and Protects against Macrophage Apoptosis in Ldlr KO Mice Journal Articles
Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase Journal Articles
Stat6 dependent goblet cell hyperplasia during intestinal nematode infection Journal Articles
Sterol Regulatory Element Binding Protein (SREBP)-1 is a novel regulator of the Transforming Growth Factor (TGF)-β receptor I (TβRI) through exosomal secretion Journal Articles
Stimulation of Glucose Uptake by the Natural Coenzyme α-Lipoic Acid/Thioctic Acid: Participation of Elements of the Insulin Signaling Pathway Journal Articles
Stimulatory and inhibitory signaling molecules that regulate renal branching morphogenesis Journal Articles
Streptomyces exploration is triggered by fungal interactions and volatile signals Journal Articles
Stress neuropeptides evoke epithelial responses via mast cell activation in the rat colon Journal Articles
Stress-responsive signal transduction mechanisms in glomerular cells Journal Articles
Stretch activation of Jun N-terminal kinase/stress-activated protein kinase in mesangial cells Journal Articles
Stretch-induced Activation of Transforming Growth Factor-β₁ in Pulmonary Fibrosis Journal Articles
Stretch-induced Raf-1 activation in mesangial cells requires actin cytoskeletal integrity Journal Articles
Stromal β-catenin overexpression contributes to the pathogenesis of renal dysplasia Journal Articles
Stromally Expressed β-Catenin Modulates Wnt9b Signaling in the Ureteric Epithelium Journal Articles
Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases Journal Articles
Subgroup-specific structural variation across 1,000 medulloblastoma genomes Journal Articles
Substance P activates Cl⁻ and K⁺ conductances in guinea-pig tracheal smooth muscle cells Journal Articles
Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability Journal Articles
Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity Journal Articles
Supraspinal locomotor centers do/do not contribute significantly to the hyperpnea of dynamic exercise in humans. Journal Articles
Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo Journal Articles
Sweet Taste in Man: A Review Journal Articles
Synapse Formation and Hypoxic Signalling in Co‐Cultures of Rat Petrosal Neurones and Carotid Body Type 1 Cells Journal Articles
Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis Journal Articles
Synergy in Induction of Increased Renal Allograft Survival after Portal Vein Infusion of Dendritic Cells Transduced to Express TGFβ and IL-10, along with Administration of CHO Cells Expressing the Regulatory Molecule OX-2 Journal Articles
Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits Journal Articles
Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways Journal Articles
Systemic acquired resistance networks amplify airborne defense cues Journal Articles
T cell‐mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells Journal Articles
TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells Journal Articles
TGF- receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung Journal Articles
TGF-β and Smad3 Signaling Link Inflammation to Chronic Fibrogenesis Journal Articles
TGFβ receptor I transactivation mediates stretch-induced Pak1 activation and CTGF upregulation in mesangial cells Journal Articles
TLR2 Plays a Pivotal Role in Mediating Mucosal Serotonin Production in the Gut Journal Articles
TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathway Journal Articles
TNF-α and Poly(I:C) induction of A20 and activation of NF-κB signaling are independent of ABCF1 in human airway epithelial cells Journal Articles
TNF-α is a critical negative regulator of type 1 immune activation during intracellular bacterial infection Journal Articles
TRIM33 prevents pulmonary fibrosis by impairing TGF-β1 signalling Journal Articles
Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR Journal Articles
Targeting AMP-activated protein kinase (AMPK) for treatment of autosomal dominant polycystic kidney disease Journal Articles
Targeting C3a/C5a receptors inhibits human mesangial cell proliferation and alleviates immunoglobulin A nephropathy in mice Journal Articles
Targeting Genes for Treatment in Idiopathic Pulmonary Fibrosis: Challenges and Opportunities, Promises and Pitfalls Journal Articles
Targeting Myelin to Optimize Plasticity of Spared Spinal Axons Journal Articles
Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology Journal Articles
Targeting apoptosis: preclinical and early clinical experience with mapatumumab, an agonist monoclonal antibody targeting TRAIL-R1 Journal Articles
Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells Journal Articles
Telomerase Mediates Vascular Endothelial Growth Factor-dependent Responsiveness in a Rat Model of Hind Limb Ischemia Journal Articles
Temtamy Preaxial Brachydactyly Syndrome Is Caused by Loss-of-Function Mutations in Chondroitin Synthase 1, a Potential Target of BMP Signaling Journal Articles
Testosterone Inhibits Adipogenic Differentiation in 3T3-L1 Cells: Nuclear Translocation of Androgen Receptor Complex with β-Catenin and T-Cell Factor 4 May Bypass Canonical Wnt Signaling to Down-Regulate Adipogenic Transcription Factors Journal Articles
Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors. Journal Articles
Testosterone inhibits transforming growth factor-β signaling during myogenic differentiation and proliferation of mouse satellite cells: Potential role of follistatin in mediating testosterone action Journal Articles
Thaxtomin A-deficient endophytic Streptomyces sp. enhances plant disease resistance to pathogenic Streptomyces scabies Journal Articles
The Antibiotic Resistome: A Guide for the Discovery of Natural Products as Antimicrobial Agents Journal Articles
The CD200 tolerance-signaling molecule and its receptor, CD200R1, are expressed in human placental villus trophoblast and in peri-implant decidua by 5 weeks’ gestation Journal Articles
The Circadian Clock Gene, Bmal1, Regulates Intestinal Stem Cell Signaling and Represses Tumor Initiation Journal Articles
The Cleaved Peptide of PAR1 Results in a Redistribution of the Platelet Surface GPIb-IX-V Complex to the Surface-Connected Canalicular System Journal Articles
The Effects of Leptin on Airway Smooth Muscle Responses Journal Articles
The GRHL2/ZEB Feedback Loop-A Key Axis in the Regulation of EMT in Breast Cancer Journal Articles
The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma Journal Articles
The Gastrin-Releasing Peptide Receptor as a Therapeutic Target in Central Nervous System Disorders Journal Articles
The Hepatic Response to Thermal Injury: Is the Liver Important for Postburn Outcomes? Journal Articles
The Herpes Simplex Virus 1-Encoded Envelope Glycoprotein B Activates NF-κB through the Toll-Like Receptor 2 and MyD88/TRAF6-Dependent Signaling Pathway Journal Articles
The Hippo Tumor Suppressor Pathway: A Brainstorming WorkshopA report on the research meeting “The Hippo Tumor Suppressor Pathway: A Brainstorming Workshop” sponsored mainly by the Regina Elena Cancer Center and the Nicola Foundation and held in Rome, Italy, on 22 and 23 April 2009. Journal Articles
The Hippo tumor suppressor pathway: a report on ‘the second workshop on the Hippo tumor suppressor pathway’ Journal Articles
The Human Microbiota in Multiple Myeloma and Proteasome Inhibitors Journal Articles
The Human Papilloma Virus E7 Oncoprotein Inhibits Transforming Growth Factor-β Signaling by Blocking Binding of the Smad Complex to Its Target Sequence Journal Articles
The Implications of Cannabinoid-Induced Metabolic Dysregulation for Cellular Differentiation and Growth Journal Articles
The Influence of Cigarette Smoking on Viral Infections Journal Articles
The Involvement of Calcium and MAP Kinase Signaling Pathways in the Production of Radiation-Induced Bystander Effects Journal Articles
The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum‐sensing signal molecule Journal Articles
The Methyltransferase Smyd1 Mediates LPS-Triggered Up-Regulation of IL-6 in Endothelial Cells Journal Articles
The NK Receptor NKp30 Mediates Direct Fungal Recognition and Killing and Is Diminished in NK Cells from HIV-Infected Patients Journal Articles
The Nitric Oxide Pathway Provides Innate Antiviral Protection in Conjunction with the Type I Interferon Pathway in Fibroblasts Journal Articles
The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm Journal Articles
The Order of Exercise during Concurrent Training for Rehabilitation Does Not Alter Acute Genetic Expression, Mitochondrial Enzyme Activity or Improvements in Muscle Function Journal Articles
The Orphan Nuclear Hormone Receptor LXRα Interacts with the Peroxisome Proliferator-activated Receptor and Inhibits Peroxisome Proliferator Signaling Journal Articles
The POZ-ZF Transcription Factor Kaiso (ZBTB33) Induces Inflammation and Progenitor Cell Differentiation in the Murine Intestine Journal Articles
The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-β Oligomer Toxicity Journal Articles
The Pulmonary Biology of Isoprostanes Journal Articles
The RING‐finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling in Drosophila Journal Articles
The Role of Dietary Fat throughout the Prostate Cancer Trajectory Journal Articles
The Role of Endoplasmic Reticulum Stress-Glycogen Synthase Kinase-3 Signaling in Atherogenesis Journal Articles
The Role of Serotonin in Breast Cancer Stem Cells Journal Articles
The Role of the TL1A/DR3 Axis in the Activation of Group 2 Innate Lymphoid Cells in Subjects with Eosinophilic Asthma Journal Articles
The Suppressor of Cytokine Signaling 3 Inhibits Leptin Activation of AMP-Kinase in Cultured Skeletal Muscle of Obese Humans Journal Articles
The Trophic Effects of Purines and Purinergic Signaling in Pathologic Reactions of Astrocytes Journal Articles
The YebC Family Protein PA0964 Negatively Regulates thePseudomonas aeruginosaQuinolone Signal System and Pyocyanin Production Journal Articles
The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades. Journal Articles
The acute phase response of the liver in inflammation. Journal Articles
The common inflammatory etiology of depression and cognitive impairment: a therapeutic target Journal Articles
The complex roles of STAT3 and STAT5 in maintaining redox balance: Lessons from STAT-mediated xCT expression in cancer cells Journal Articles
The control of testicular androgen production in the goldfish: Effects of activators of different intracellular signalling pathways Journal Articles
The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo Journal Articles
The dynamic microbe: green fluorescent protein brings bacteria to light Journal Articles
The effect of montelukast, budesonide alone, and in combination on exercise-induced bronchoconstriction Journal Articles
The effect of smoking cessation pharmacotherapies on pancreatic beta cell function Journal Articles
The effects of 17-α-ethinylestradiol (EE2) on molecular signaling cascades in mummichog (Fundulus heteroclitus) Journal Articles
The endothelium in lung fibrosis: a core signaling hub in disease pathogenesis? Journal Articles
The fate of released histamine: reception, response and termination. Conferences
The fight between the teleost fish immune response and aquatic viruses Journal Articles
The function of IGF-IR in NNK-mediated lung tumorigenesis Journal Articles
The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system Journal Articles
The impact of body mass index in gene expression of reelin pathway mediators in individuals with schizophrenia and mood disorders: A post-mortem study Journal Articles
The integrative role of leptin, oestrogen and the insulin family in obesity‐associated breast cancer: potential effects of exercise Journal Articles
The interplay between the intestinal microbiota and the brain Journal Articles
The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms Journal Articles
The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus Journal Articles
The neurotrophic factor MANF regulates autophagy and lysosome function to promote proteostasis in Caenorhabditis elegans. Journal Articles
The p53/p21 DNA damage-signaling pathway is defective in most meningioma cells Journal Articles
The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway Journal Articles
The plant signal salicylic acid shuts down expression of the vir regulon and activates quormone-quenching genes in Agrobacterium Journal Articles
The rapid effects of estrogen: a mini-review Journal Articles
The recognition of biomaterials: Pattern recognition of medical polymers and their adsorbed biomolecules Journal Articles
The regulation of cardiac activity by nitric oxide (NO) in the Vietnamese stick insect, Baculum extradentatum Journal Articles
The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise Journal Articles
The role of ICP0-Null HSV-1 and interferon signaling defects in the effective treatment of breast adenocarcinoma Journal Articles
The role of ghrelin in the regulation of glucose homeostasis Journal Articles
The role of microRNAs in prethrombotic status associated with coronary artery disease Journal Articles
The role of serotonin and its receptors in activation of immune responses and inflammation Journal Articles
The role of sphingosine kinase 2 in alcoholic liver disease Journal Articles
The role of the type I insulin-like growth factor receptor (IGF-IR) in glomerular integrity Journal Articles
The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression Journal Articles
The sex-limited effects of mutations in the EGFR and TGF-β signaling pathways on shape and size sexual dimorphism and allometry in the Drosophila wing Journal Articles
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation Journal Articles
The telomerase tale in vascular aging: regulation by estrogens and nitric oxide signaling Journal Articles
The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors Journal Articles
The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis Journal Articles
The tissue polarity gene nemo carries out multiple roles in patterning during Drosophila development Journal Articles
The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells Journal Articles
The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout Journal Articles
Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia Journal Articles
Therapeutic approaches for muscle wasting disorders Journal Articles
Thermal Injury Activates the eEF2K‐Dependent eEF2 Pathway in Pediatric Patients Journal Articles
Thermosensing Coordinates a Cis-regulatory Module for Transcriptional Activation of the Intracellular Virulence System in Salmonella enterica Serovar Typhimurium Journal Articles
Thrombospondin-1/CD47 signaling modulates transmembrane cation conductance, survival, and deformability of human red blood cells Journal Articles
Thyroid hormone receptor α in breast cancer: prognostic and therapeutic implications Journal Articles
Thyroid hormone regulation of thermal acclimation in ectotherms: Physiological mechanisms and ecoevolutionary implications Journal Articles
Tie2 protects the vasculature against thrombus formation in systemic inflammation Journal Articles
Tolerance Signaling Molecules Journal Articles
Tolerance Signaling Molecules and Pregnancy: IDO, Galectins, and the Renaissance of Regulatory T Cells Journal Articles
Toll-like Receptor 9, CpG DNA and Innate Immunity Journal Articles
Toll-like receptors 2 and 7 mediate coagulation activation and coagulopathy in murine sepsis. Journal Articles
Toll‐Like Receptor (TLR)–3, but Not TLR4, Agonist Protects against Genital Herpes Infection in the Absence of Inflammation Seen with CpG DNA Journal Articles
Transactivation by PPAR/RXR heterodimers in yeast is potentiated by exogenous fatty acid via a pathway requiring intact peroxisomes. Journal Articles
Transcriptome Profiling and Functional Analysis ofAgrobacterium tumefaciensReveals a General Conserved Response to Acidic Conditions (pH 5.5) and a Complex Acid-Mediated Signaling Involved inAgrobacterium-Plant Interactions Journal Articles
Transcriptome and translational signaling following endurance exercise in trained skeletal muscle: impact of dietary protein Journal Articles
Transcriptomic and proteomic analyses in bone tumor cells: Deciphering parathyroid hormone-related protein regulation of the cell cycle and apoptosis Journal Articles
Transcriptomic profiling of progesterone in the male fathead minnow (Pimephales promelas) testis Journal Articles
Transfusion‐related immunomodulation due to peripheral blood dendritic cells expressing the CD200 tolerance signaling molecule and alloantigen Journal Articles
Transgenic plants with altered ethylene biosynthesis or perception Journal Articles
Transplantation of human hematopoietic repopulating cells: mechanisms of regeneration and differentiation using human???mouse xenografts Journal Articles
Treatment with apolipoprotein A1 protects mice against doxorubicin-induced cardiotoxicity in a scavenger receptor class B, type I-dependent manner Journal Articles
Treatment-induced cell cycle kinetics dictate tumor response to chemotherapy Journal Articles
Trimethylamine N-oxide impairs β-cell function and glucose tolerance Journal Articles
Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone Journal Articles
Tryptophan‐derived serotonin‐kynurenine balance in immune activation and intestinal inflammation Journal Articles
Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling Journal Articles
Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity Journal Articles
Type I IFN signaling on dendritic cells is required for NK cell-mediated anti-tumor immunity Journal Articles
Type I interferon signalling is not required for the induction of endotoxin tolerance Journal Articles
Type IV Pilin Proteins: Versatile Molecular Modules Journal Articles
Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages Journal Articles
Tyrosine 740 Phosphorylation of Discoidin Domain Receptor 2 by Src Stimulates Intramolecular Autophosphorylation and Shc Signaling Complex Formation Journal Articles
Tyrosine phosphorylation and cadherin/catenin function Journal Articles
UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways Journal Articles
Uncoupling of Pro- and Anti-Inflammatory Properties of Staphylococcus aureus Journal Articles
Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo Journal Articles
Understanding the Role of DISC1 in Psychiatric Disease and during Normal Development Journal Articles
Update on bipolar disorder biomarker candidates Journal Articles
Upregulating Nrf2-dependent antioxidant defenses in Pacific oysters Crassostrea gigas: Investigating the Nrf2/Keap1 pathway in bivalves Journal Articles
Upregulation of IL-17A/F from human lung tissue explants with cigarette smoke exposure: implications for COPD Journal Articles
Upregulation of MMP-13 via Runx2 in the stromal cell of Giant Cell Tumor of Bone Journal Articles
Upregulation of microRNA-532 enhances cardiomyocyte apoptosis in the diabetic heart Journal Articles
Using G-deleted vesicular stomatitis virus to probe the innate anti-viral response Journal Articles
VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents Journal Articles
Varicose Remodeling of Veins Is Suppressed by 3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Inhibitors Journal Articles
Vascular Endothelial Tissue Factor Pathway Inhibitor Kinetics in Culture Following Exposure to DX-9065a—A Selective and Direct Factor Xa Inhibitor Journal Articles
Vascular Regenerative Cell Exhaustion in Diabetes: Translational Opportunities to Mitigate Cardiometabolic Risk Journal Articles
Vascular Research at INABIS 98 Journal Articles
Vascular smooth muscle cell proliferation as a therapeutic target. Part 1: molecular targets and pathways. Journal Articles
Vascular β-adrenoceptor function in hypertension and in ageing Journal Articles
Vasculoprotective effects of ginger (Zingiber officinale Roscoe) and underlying molecular mechanisms Journal Articles
Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles Journal Articles
Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle Journal Articles
Vasopressin Increases Intracellular NO Concentration via Ca ²⁺ Signaling in Inner Medullary Collecting Duct Conferences
Vasopressin increases intracellular NO concentration via Ca(2+) signaling in inner medullary collecting duct. Journal Articles
Voices from within: gut microbes and the CNS Journal Articles
W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity Journal Articles
What have we learned from basic science studies on idiopathic pulmonary fibrosis? Journal Articles
Whole-cell and perforated-patch recordings from O2-sensitive rat carotid body cells grown in short- and long-term culture Journal Articles
Wnt3a Activates Dormant c-Kit− Bone Marrow-Derived Cells with Short-Term Multilineage Hematopoietic Reconstitution Capacity Journal Articles
Wnt7a treatment ameliorates muscular dystrophy Journal Articles
cAMP activation of PKA defines an ancient signaling mechanism Journal Articles
miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis Journal Articles
miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells Journal Articles
nMET, A New Target in Recurrent Cancer Journal Articles
p53: The pivot between cell cycle arrest and senescence Journal Articles
p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade Journal Articles
α-Adrenoceptor subtypes of dog saphenous vein: Another unusual property Journal Articles
β-Catenin Causes Renal Dysplasia via Upregulation of Tgfβ2 and Dkk1 Journal Articles
β-Catenin Overexpression in the Metanephric Mesenchyme Leads to Renal Dysplasia Genesis via Cell-Autonomous and Non–Cell-Autonomous Mechanisms Journal Articles
β-Catenin in stromal progenitors controls medullary stromal development Journal Articles
β-Catenin/CBP–Dependent Signaling Regulates TGF-β–Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells Journal Articles
β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens Journal Articles
β-Subunit of the voltage-gated Ca ²⁺ channel Cav1.2 drives signaling to the nucleus via H-Ras Journal Articles
β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer Journal Articles
β2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis Journal Articles
β‐Catenin in the kidney stroma modulates pathways and genes to regulate kidney development Journal Articles
β‐adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling Journal Articles
γ‐aminobutyric acid nurtures allergic asthma Journal Articles

Signal Transduction Concept

Vocabulary Service

Overview

subject area of