Signal Transduction
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1,25-Dihydroxyvitamin D3Primes Acute Promyelocytic Cells for TPA-Induced Monocytic Differentiation through Both PKC and Tyrosine Phosphorylation Cascades Academic Article
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1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells Academic Article
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2-[<sup>125</sup>I]Iodomelatonin Binding in the Brains of Four Salmonids Academic Article
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2017 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis Academic Article
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4-phenylbutyrate and valproate treatment attenuates the progression of atherosclerosis and stabilizes existing plaques Academic Article
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8-isoprostaglandin E2 activates Ca2+-dependent K+ current via cyclic AMP signaling pathway in murine renal artery Academic Article
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AJP-Cell Physiology begins a new Theme of Reviews on “Inflammation: From Cellular Mechanisms to Immune Cell Education” Academic Article
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Chlamydia pneumoniae
Infection of Human Endothelial Cells Induces Proliferation of Smooth Muscle Cells via an Endothelial Cell-Derived Soluble Factor(s) Academic Article
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Cynara scolymus affects malignant pleural mesothelioma by promoting apoptosis and restraining invasion Academic Article
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Salmonella enterica
Serovar Typhimurium Exploits Toll-Like Receptor Signaling during the Host-Pathogen Interaction Academic Article
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OX
40L blockade and allergen‐induced airway responses in subjects with mild asthma Academic Article
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PhoR
autokinase activity is controlled by an intermediate in wall teichoic acid metabolism that is sensed by the intracellular
PAS
domain during the
PhoPR
‐mediated phosphate limitation response of
B
acillus subtilis Academic Article
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cTAZ
: a safeguard factor of antiviral response Academic Article
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A Budding Relationship: Bacterial Extracellular Vesicles in the Microbiota-Gut-Brain Axis Academic Article
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A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease Academic Article
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A Dietary Supplement Abolishes Age-Related Cognitive Decline in Transgenic Mice Expressing Elevated Free Radical Processes Academic Article
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A Hydroponic Co-cultivation System for Simultaneous and Systematic Analysis of Plant/Microbe Molecular Interactions and Signaling Academic Article
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A Mechanism of Extreme Growth and Reliable Signaling in Sexually Selected Ornaments and Weapons Academic Article
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A PPARγ mutant serves as a dominant negative inhibitor of PPAR signaling and is localized in the nucleus Academic Article
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A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation Academic Article
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A STAT3-NFkB/DDIT3/CEBPβ axis modulates ALDH1A3 expression in chemoresistant cell subpopulations Academic Article
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A by-product of glutathione production in cancer cells may cause disruption in bone metabolic processesThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease. Academic Article
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A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation Academic Article
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A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials Academic Article
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A general mechanism for conditional expression of exaggerated sexually-selected traits Academic Article
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A hybrid model to study how late long-term potentiation is affected by faulty molecules in an intraneuronal signaling network regulating transcription factor CREB Academic Article
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A large-scale candidate gene association study of age at menarche and age at natural menopause Academic Article
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A macrophage-stimulating compound from a screen of microbial natural products Academic Article
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A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade Academic Article
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A novel function for the competence inducing peptide, XIP, as a cell death effector ofStreptococcus mutans Academic Article
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A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells Academic Article
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A p56 Ligand Serves as a Coactivator of an Orphan Nuclear Hormone Receptor Academic Article
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A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients. Academic Article
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A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia Academic Article
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A putative Lipid Transfer Protein involved in systemic resistance signaling in Arabidopsis Academic Article
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A quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model Academic Article
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A randomized, placebo‐controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER) Academic Article
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A role for the TGFβ-Par6 polarity pathway in breast cancer progression Academic Article
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A role for the scavenger receptor, class B type I in high density lipoprotein dependent activation of cellular signaling pathways Academic Article
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A role of SIPL1/SHARPIN in promoting resistance to hormone therapy in breast cancer Academic Article
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A set of NF-κB–regulated microRNAs induces acquired TRAIL resistance in Lung cancer Academic Article
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A thrombin receptor function for platelet glycoprotein Ib–IX unmasked by cleavage of glycoprotein V Academic Article
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A translational view of the genetics of lipodystrophy and ectopic fat deposition. Chapter
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ABCF1 Regulates dsDNA-induced Immune Responses in Human Airway Epithelial Cells Academic Article
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AHR signaling is induced by infection with coronaviruses Academic Article
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AMP-activated protein kinase (AMPK) beyond metabolism Academic Article
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AMP-activated protein kinase is required for exercise-induced peroxisome proliferator-activated receptor γ co-activator 1α translocation to subsarcolemmal mitochondria in skeletal muscle Academic Article
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AMP-activated protein kinase: the current landscape for drug development Academic Article
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AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity Academic Article
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AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis Academic Article
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AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation Academic Article
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AMPK-dependent hormonal regulation of whole-body energy metabolism Academic Article
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AMPK-independent pathways regulate skeletal muscle fatty acid oxidation Academic Article
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AP-2α knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis Academic Article
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ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres Academic Article
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ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes Academic Article
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ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence Academic Article
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Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia Academic Article
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Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients Academic Article
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Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy Academic Article
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Abundance of cyclin B1 regulates γ-radiation–induced apoptosis Academic Article
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Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression Academic Article
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Actions of vasopressin and the Ca(2+)-ATPase inhibitor, thapsigargin, on Ca2+ signaling in hepatocytes. Academic Article
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Activated calcineurin ameliorates contraction-induced injury to skeletal muscles ofmdxdystrophic mice Academic Article
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Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells Academic Article
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Activation of mesangial cell signaling cascades in response to mechanical strain Academic Article
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Activation of the Hedgehog Signaling Pathway in the Developing Lens Stimulates EctopicFoxE3Expression and Disruption in Fiber Cell Differentiation Academic Article
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Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis Academic Article
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Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease Academic Article
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Activity Regulates Positive and Negative Neurotrophin-Derived Signals to Determine Axon Competition Academic Article
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Activity and expression ofXenopus laevis matrix metalloproteinases: Identification of a novel role for the hormone prolactin in regulating collagenolysis in both amphibians and mammals Academic Article
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Addressing taxane resistance in metastatic castration-resistant prostate cancer: a focus on chaperone proteins Academic Article
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Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway Academic Article
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Adiponectin inhibits oxidative stress in human prostate carcinoma cells Academic Article
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Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy Academic Article
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Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats Academic Article
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Adipose tissue as an endocrine organ Academic Article
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Administration of dexamethasone protects mice against ischemia/reperfusion induced renal injury by suppressing PI3K/AKT signaling. Academic Article
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Age-Related Resistance in Arabidopsis Is a Developmentally Regulated Defense Response to Pseudomonas syringae Academic Article
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Airway smooth muscle in asthma: Phenotype plasticity and function Conference Paper
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Akt Mediates Mechanical Strain-Induced Collagen Production by Mesangial Cells Academic Article
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Alcohol Ingestion Impairs Maximal Post-Exercise Rates of Myofibrillar Protein Synthesis following a Single Bout of Concurrent Training Academic Article
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Allergen-induced increase in bone marrow progenitors in airway hyperresponsive dogs: regulation by a serum hemopoietic factor. Academic Article
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Allosteric pluripotency: challenges and opportunities Academic Article
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Alterations in Skeletal Muscle Cell Homeostasis in a Mouse Model of Cigarette Smoke Exposure Academic Article
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Alterations of immune response of non-small cell lung cancer with Azacytidine Academic Article
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Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling Academic Article
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Amplification of MUC1 in prostate cancer metastasis and CRPC development Academic Article
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Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis Academic Article
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An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity Academic Article
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An emerging role for Wnt and GSK3 signaling pathways in schizophrenia Academic Article
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An inducible model of human amylin overexpression reveals diverse transcriptional changes Academic Article
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Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture Academic Article
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Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise Academic Article
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Analysis of the Human Fetal Liver Hematopoietic Microenvironment Academic Article
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Androgen Induces Adaptation to Oxidative Stress in Prostate Cancer: Implications for Treatment with Radiation Therapy Academic Article
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Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression Academic Article
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Angiogenesis in the Placenta: The Role of Reactive Oxygen Species Signaling Academic Article
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Angiotensin II mobilizes intracellular calcium and activates pannexin-1 channels in rat carotid body type II cells via AT1receptors Academic Article
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Anormalidades neuropatológicas e neuroquímicas no transtorno afetivo bipolar Academic Article
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Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions Academic Article
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Anti-Inflammatory Effects of Tanshinone IIA on Atherosclerostic Vessels of Ovariectomized ApoE-/- Mice are Mediated by Estrogen Receptor Activation and Through the ERK Signaling Pathway Academic Article
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Anti-pneumococcal deficits of monocyte-derived macrophages from the advanced-age, frail elderly and related impairments in PI3K-AKT signaling Academic Article
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Antialarmins for treatment of asthma Academic Article
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Antibodies to rat soluble IL-6 receptor stimulate B9 hybridoma cell proliferation Academic Article
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Antifibrotic Role of αB-Crystallin Inhibition in Pleural and Subpleural Fibrosis Academic Article
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Antiplatelet Effect of Active Components Derived from Chinese Herbal Medicine Academic Article
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Apoptosis induction by eIF5A1 involves activation of the intrinsic mitochondrial pathway Academic Article
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Apoptosis is initiated in human keratinocytes exposed to signalling factors from microbeam irradiated cells Academic Article
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Apoptosis is signalled early by low doses of ionising radiation in a radiation-induced bystander effect Academic Article
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Are SIRT1 activators another indirect method to increase AMPK for beneficial effects on aging and the metabolic syndrome? Academic Article
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Are endothelium-derived hyperpolarizing and contracting factors isoprostanes? Academic Article
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Argos and Spitz group genes function to regulate midline glial cell number in Drosophila embryos Academic Article
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Aryl hydrocarbon receptor control of a disease tolerance defence pathway Academic Article
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Association of Interleukin-6 Signalling with the Muscle Stem Cell Response Following Muscle-Lengthening Contractions in Humans Academic Article
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Association of Phosphorylated Epidermal Growth Factor Receptor with Survival in Patients with Locally Advanced Non-small Cell Lung Cancer Treated with Radiotherapy Academic Article
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Asthma therapy: how far have we come, why did we fail and where should we go next? Academic Article
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Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis Academic Article
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Atorvastatin Delays Murine Platelet Activation In Vivo Even in the Absence of Endothelial NO Synthase Academic Article
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Attenuation ofClostridium difficiletoxin-induced damage to epithelial barrier by ecto-5′-nucleotidase (CD73) and adenosine receptor signaling Academic Article
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Axon repulsion from the midline of the Drosophila CNS requires slit function Academic Article
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B Cell Maintenance of Subcapsular Sinus Macrophages Protects against a Fatal Viral Infection Independent of Adaptive Immunity Academic Article
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B7RP-1 Is Not Required for the Generation of Th2 Responses in a Model of Allergic Airway Inflammation but Is Essential for the Induction of Inhalation Tolerance Academic Article
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BDNF/TrkB Content and Interaction with Gastrin-Releasing Peptide Receptor Blockade in Colorectal Cancer Academic Article
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BH3-only proteins: Orchestrators of apoptosis Academic Article
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BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer Academic Article
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Bacterial Peptidoglycan Stimulates Adipocyte Lipolysis via NOD1 Academic Article
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Bacterial lipids Academic Article
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Basic and Translational Research in Intracerebral Hemorrhage Academic Article
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Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line Academic Article
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Beneficial effects of resveratrol on respiratory chain defects in patients' fibroblasts involve estrogen receptor and estrogen-related receptor alpha signaling Academic Article
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Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and prostaglandin E2 (PGE2) output Academic Article
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Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways Academic Article
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Binding of Anti-GRP78 Autoantibodies to Cell Surface GRP78 Increases Tissue Factor Procoagulant Activity via the Release of Calcium from Endoplasmic Reticulum Stores Academic Article
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Bio-acoustic signaling; exploring the potential of sound as a mediator of low-dose radiation and stress responses in the environment Academic Article
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Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region Academic Article
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Bisphosphonates Target B Cells to Enhance Humoral Immune Responses Academic Article
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Bone Morphogenetic Proteins Regulate the Developmental Program of Human Hematopoietic Stem Cells Academic Article
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Bone cancer-induced pain is associated with glutamate signalling in peripheral sensory neurons Academic Article
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Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract Academic Article
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Bystander effects of ionizing radiation can be modulated by signaling amines Academic Article
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Bystander signal production and response are independent processes which are cell line dependent Academic Article
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Bystander-induced differentiation: A major response to targeted irradiation of a urothelial explant model Academic Article
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C. elegans electrotaxis behavior is modulated by heat shock response and unfolded protein response signaling pathways Academic Article
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CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection Academic Article
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CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence Academic Article
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CD200-dependent and nonCD200-dependant pathways of NK cell suppression by human IVIG Academic Article
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CD23-mediated transport of IgE/immune complexes across human intestinal epithelium: role of p38 MAPK Academic Article
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CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis Academic Article
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CDP-diacylglycerol, a critical intermediate in lipid metabolism Academic Article
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CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK Academic Article
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CO2/pH Chemosensory Signaling in Co-Cultures of Rat Carotid Body Receptors and Petrosal Neurons: Role of ATP and ACh Academic Article
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COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux Academic Article
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CXCL12/CXCR4 Signaling Enhances Human PSC-Derived Hematopoietic Progenitor Function and Overcomes Early In Vivo Transplantation Failure Academic Article
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CXCL9 Contributes to Antimicrobial Protection of the Gut during Citrobacter rodentium Infection Independent of Chemokine-Receptor Signaling Academic Article
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CXCR3 Signaling Is Required for Restricted Homing of Parenteral Tuberculosis Vaccine–Induced T Cells to Both the Lung Parenchyma and Airway Academic Article
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CYFIP/Sra-1 Controls Neuronal Connectivity in Drosophila and Links the Rac1 GTPase Pathway to the Fragile X Protein Academic Article
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Ca2+/calmodulin-dependent protein kinase IIβ and IIδ mediate TGFβ-induced transduction of fibronectin and collagen in human pulmonary fibroblasts Academic Article
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Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β Academic Article
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Caenorhabditis elegans SMA-10/LRIG Is a Conserved Transmembrane Protein that Enhances Bone Morphogenetic Protein Signaling Academic Article
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Calcium Regulation and Contractile Dysfunction of Smooth Muscle Academic Article
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Caloxin: a novel plasma membrane Ca2+pump inhibitor Academic Article
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Canadian Association of Neurosciences Review: Polyglutamine Expansion Neurodegenerative Diseases Academic Article
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Cancer phenomics: RET and PTEN as illustrative models Academic Article
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Canonical WNT/β-catenin signaling is required for ureteric branching Academic Article
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Captopril treatment induces hyperplasia but inhibits myonuclear accretion following severe myotrauma in murine skeletal muscle Academic Article
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Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans Academic Article
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Carotid Body Adaptation to Hypoxia: Cellular and Molecular Mechanisms in vitro Academic Article
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Caveolin-1 in the Pathogenesis of Diabetic Nephropathy: Potential Therapeutic Target? Academic Article
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Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy Academic Article
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Cell-free Tumor Microparticle Vaccines Stimulate Dendritic Cells via cGAS/STING Signaling Academic Article
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Cells Exposed to Sublethal Oxidative Stress Selectively Attract Monocytes/Macrophages via Scavenger Receptors and MyD88-Mediated Signaling Academic Article
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Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness Academic Article
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Cellular metabolic homeostasis during large-scale change in ATP turnover rates in muscles. Academic Article
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Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function Academic Article
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Changes in HIF-1α protein, pyruvate dehydrogenase phosphorylation, and activity with exercise in acute and chronic hypoxia Academic Article
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Changes in expression of the CD200 tolerance-signaling molecule and its receptor (CD200R) by villus trophoblasts during first trimester missed abortion and in chronic histiocytic intervillositis Academic Article
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Chapter 7 Evidence that the Merkel cell is not the transducer in the mechanosensory Merkel cell – neurite complex Academic Article
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Characterization of Chemokine Receptors Expressed in Primitive Blood Cells During Human Hematopoietic Ontogeny Academic Article
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Characterization of Radioprotective, Radiomitigative and Bystander Signaling Modulating Effects of Endogenous Metabolites – Phenylacetate, Ursodeoxycholate and Tauroursodeoxycholate – on HCT116 Human Colon Carcinoma Cell Line Academic Article
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Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance Academic Article
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Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells Academic Article
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Characterizing the Role of Glycogen Synthase Kinase-3α/β in Macrophage Polarization and the Regulation of Pro-Atherogenic Pathways in Cultured Ldlr-/- Macrophages Academic Article
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Chemical Interactions between Organisms in Microbial Communities Academic Article
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Chemosensing and signal transduction in bacteria Academic Article
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Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signaling. Academic Article
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Chlamydiae Host Cell Interactions Revealed Using DNA Microarrays Academic Article
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Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle Academic Article
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Chronic modulation of AMP-Kinase, Akt and mTOR pathways by ionizing radiation in human lung cancer xenografts Academic Article
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Cigarette Smoke Exposure Triggers the Autophagic Cascade via Activation of the AMPK Pathway in Mice1 Academic Article
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Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis inSmad3knockout mice Academic Article
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Cigarette smoke upregulates pulmonary vascular matrix metalloproteinases via TNF-α signaling Academic Article
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Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice Academic Article
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Ciliary Neurotrophic Factor Suppresses Hypothalamic AMP-Kinase Signaling in Leptin-Resistant Obese Mice Academic Article
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Circulating Peroxiredoxin-1 is a novel damage-associated molecular pattern and aggravates acute liver injury via promoting inflammation Academic Article
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Class A Scavenger Receptor–Mediated Double-Stranded RNA Internalization Is Independent of Innate Antiviral Signaling and Does Not Require Phosphatidylinositol 3-Kinase Activity Academic Article
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Classification, hepatotoxic mechanisms, and targets of the risk ingredients in traditional Chinese medicine-induced liver injury Academic Article
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Clinical Implications of Targeting the JAK-STAT Pathway in Psoriatic Disease: Emphasis on the TYK2 Pathway Academic Article
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Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia Academic Article
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Collagen I induction by high glucose levels is mediated by epidermal growth factor receptor and phosphoinositide 3-kinase/Akt signalling in mesangial cells Academic Article
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Combinatorial therapeutic activation with heparin and AICAR stimulates additive effects on utrophin A expression in dystrophic muscles Academic Article
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Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development Academic Article
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Communication in bacteria: an ecological and evolutionary perspective Academic Article
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Communication of Radiation-Induced Signals in Vivo between DNA Repair Deficient and Proficient Medaka (Oryzias latipes) Academic Article
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Communication of ionising radiation signals – a tale of two fish Academic Article
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Comparative Proteomics Analysis of Arabidopsis Phloem Exudates Collected During the Induction of Systemic Acquired Resistance Academic Article
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Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress Academic Article
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Competence for collagenase gene expression by tissue fibroblasts requires activation of an interleukin 1 alpha autocrine loop. Academic Article
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Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma Academic Article
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Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells Academic Article
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Conditioned medium from hypoxia-treated adipocytes renders muscle cells insulin resistant Academic Article
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Conserved Features and Evolutionary Shifts of the EDA Signaling Pathway Involved in Vertebrate Skin Appendage Development Academic Article
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Conserved mechanism of Wnt signaling function in the specification of vulval precursor fates in C. elegans and C. briggsae Academic Article
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Contactin 1: An Important and Emerging Oncogenic Protein Promoting Cancer Progression and Metastasis Academic Article
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Contraction-related stimuli regulate GLUT4 traffic in C2C12-GLUT4mycskeletal muscle cells Academic Article
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Control of Pathogenic CD4 T Cells and Lethal Immunopathology by Signaling Immunoadaptor DAP12 during Influenza Infection Academic Article
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Controlling skeletal muscle CPT-I malonyl-CoA sensitivity: the importance of AMPK-independent regulation of intermediate filaments during exercise Academic Article
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Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma Academic Article
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Cooperation in signal transduction of extracellular guanosine 5′ triphosphate and nerve growth factor in neuronal differentiation of PC12 cells Academic Article
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Coordinated Regulation of Two Independent Cell-Cell Signaling Systems and Swarmer Differentiation in
Salmonella enterica
Serovar Typhimurium Academic Article
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Coordination of metabolic plasticity in skeletal muscle Academic Article
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Corneal development: Role of the periocular mesenchyme and bi-directional signaling Academic Article
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Critical Illness-Related Corticosteroid Insufficiency (CIRCI) Academic Article
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Critical Role of Natural Killer Cells in Lung Immunopathology During Influenza Infection in Mice Academic Article
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Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM) Academic Article
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Cross-talk between Orphan Nuclear Hormone Receptor RZRα and Peroxisome Proliferator-activated Receptor α in Regulation of the Peroxisomal Hydratase-Dehydrogenase Gene Academic Article
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Crosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis Academic Article
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Crosstalk between the Unfolded Protein Response and NF-κB-Mediated Inflammation in the Progression of Chronic Kidney Disease Academic Article
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Crosstalk between the thyroid hormone and peroxisome proliferator-activated receptors in regulating peroxisome proliferator-responsive genes Academic Article
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Cytokine Regulation of AMPK signalling Academic Article
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Cytokine control of acute phase protein expression. Academic Article
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Cytokine-Induced Hepatic Apoptosis Is Dependent on FGL2/Fibroleukin: The Role of Sp1/Sp3 and STAT1/PU.1 Composite cis Elements Academic Article
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Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130) Academic Article
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DNA Repair Signaling of Huntingtin: The Next Link Between Late-Onset Neurodegenerative Disease and Oxidative DNA Damage Academic Article
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Dancing in and out of the nucleus: p120ctn and the transcription factor Kaiso Academic Article
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Danger, diversity and priming in innate antiviral immunity Academic Article
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Deconstructing human embryonic stem cell cultures: niche regulation of self-renewal and pluripotency Academic Article
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Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis Academic Article
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Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Is the Result of Altered Notch Signaling Academic Article
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Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid Academic Article
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Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice Academic Article
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Deletion ofMAP2K2/MEK2: a novel mechanism for a RASopathy? Academic Article
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Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis Academic Article
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Differences between platelet phosphoinositide metabolism stimulated by thrombin or SFLLRN are not accounted for by interaction of thrombin with glycoprotein Ib Academic Article
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Differences in Functional Consequences and Signal Transduction Induced by IL-3, IL-5, and Nerve Growth Factor in Human Basophils Academic Article
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Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle Academic Article
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Differential regulation of striatal G protein levels following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration in C57 BL/6 mice Academic Article
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Dimerization Is Required for the Activity of the Protein Histidine Kinase CheA That Mediates Signal Transduction in Bacterial Chemotaxis Academic Article
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Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance Academic Article
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Diminished contraction-induced intracellular signaling towards mitochondrial biogenesis in aged skeletal muscle Academic Article
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Direct Microbicidal Activity of Cytotoxic T-Lymphocytes Academic Article
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Disassembly of the actin network inhibits insulin-dependent stimulation of glucose transport and prevents recruitment of glucose transporters to the plasma membrane. Academic Article
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Disordered Regions Flanking Ordered Domains Modulate Signaling Transduction Academic Article
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Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling Academic Article
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Disruption of β-catenin/CBP signaling inhibits human airway epithelial–mesenchymal transition and repair Academic Article
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Disruptive physiology: olfaction and the microbiome-gut-brain axis Academic Article
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Dissociation of AMPK activity and ACCβ phosphorylation in human muscle during prolonged exercise Academic Article
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Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression Academic Article
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Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice Academic Article
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Distinguishing Between Mouse and Human Pluripotent Stem Cell Regulation: The Best Laid Plans of Mice and Men Academic Article
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Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development Academic Article
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Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation Academic Article
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Druggable targets in pediatric neurocutaneous melanocytosis: Molecular and drug sensitivity studies in xenograft and ex vivo tumor cell culture to identify agents for therapy Academic Article
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Dual Pathway for Promotion of Stem Cell Neural Differentiation Mediated by Gold Nanocomposites Academic Article
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Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract Academic Article
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Dual roles of parathyroid hormone related protein in TGF-β1 signaling and fibronectin up-regulation in mesangial cells Academic Article
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Dual-action peptides: a new strategy in the treatment of diabetes-associated neuropathy Academic Article
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Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human Academic Article
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Dysfunctional Nrf2–Keap1 redox signaling in skeletal muscle of the sedentary old Academic Article
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Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK Academic Article
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EGF Decreases the Abundance of MicroRNAs That Restrain Oncogenic Transcription Factors Academic Article
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ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response. Academic Article
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Early Intraplatelet Signaling Enhances the Release of Human Platelet PAR-1 and -4 Amino-Terminal Peptides in Response to Thrombin Academic Article
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Early cardiac development: A Wnt beat away Academic Article
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Eccentric Exercise Activates Novel Transcriptional Regulation of Hypertrophic Signaling Pathways Not Affected by Hormone Changes Academic Article
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Editorial: You give me fever: transcriptional responses to LPS Academic Article
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Effect of dose rate on the radiation-induced bystander response Academic Article
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Effect of gamma radiation on the production of bystander signals from three earthworm species irradiated in vivo Academic Article
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Effects of Activators of Different Intracellular Signaling Pathways on Steroid Production by Goldfish Vitellogenic Ovarian Follicles Academic Article
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Effects of Chronic Treatment of Haloperidol and Clozapine on Levels of G-Protein Subunits in Rat Striatum Academic Article
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Effects of Dystrophin Isoforms on Signal Transduction through Neural Retina: Genotype–Phenotype Analysis of Duchenne Muscular Dystrophy Mouse Mutants Academic Article
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Effects of Maternal Dexamethasone Treatment Early in Pregnancy on Glucocorticoid Receptors in the Ovine Placenta Academic Article
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Effects of MeCh, thapsigargin, and La3+ on plasmalemmal and intracellular Ca2+ transport in lacrimal acinar cells Academic Article
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Effects of Reactive Oxygen and Nitrogen Species on TrkA Expression and Signalling: Implications for proNGF in Aging and Alzheimer’s Disease Academic Article
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Effects of biomaterial-induced inflammation on fibrosis and rejection Academic Article
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Elevated SOCS3 and altered IL-6 signaling is associated with age-related human muscle stem cell dysfunction Academic Article
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Elevated basal transcription can underlie timothy channel association with autism related disorders Academic Article
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Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule Academic Article
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Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis Academic Article
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Endothelin-1, but not angiotensin II, induces afferent arteriolar myosin diphosphorylation as a potential contributor to prolonged vasoconstriction Academic Article
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Endurance training partially reverses dietary-induced leptin resistance in rodent skeletal muscle Academic Article
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Energy-stress-mediated AMPK activation inhibits ferroptosis Academic Article
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Enhanced Amino Acid Sensitivity of Myofibrillar Protein Synthesis Persists for up to 24 h after Resistance Exercise in Young Men1–3 Academic Article
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Enhanced BDNF signalling following chronic hypoxia potentiates catecholamine release from cultured rat adrenal chromaffin cells Academic Article
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Enhanced Lipid Oxidation and Maintenance of Muscle Insulin Sensitivity Despite Glucose Intolerance in a Diet-Induced Obesity Mouse Model Academic Article
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Enhanced TH17 Responses in Patients with IL10 Receptor Deficiency and Infantile-onset IBD Academic Article
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Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662 Academic Article
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Enhanced adenosine A2breceptor signaling facilitates stimulus-induced catecholamine secretion in chronically hypoxic carotid body type I cells Academic Article
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Epidermal Growth Factor Receptor and Transforming Growth Factor-β Signaling Contributes to Variation for Wing Shape in Drosophila melanogaster Academic Article
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Epidermal Growth Factor Receptor: Pathway, Therapies, and Pipeline Academic Article
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Epidermal growth factor receptor deficiency: Expanding the phenotype beyond infancy Academic Article
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Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1 Academic Article
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Epigenetic Regulation of SOX9 by the NF-κB Signaling Pathway in Pancreatic Cancer Stem Cells Academic Article
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Epigenetic induction of melatonin MT 1 receptors by valproate: Neurotherapeutic implications Academic Article
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Epigenetic mechanisms of melatonin action in human SH-SY5Y neuroblastoma cells Academic Article
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Epigenetic silencing of miR-145-5p contributes to brain metastasis Academic Article
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ErbB Receptor Signaling and Therapeutic Resistance to Aromatase Inhibitors Conference Paper
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Estrogen Receptor β Is a Novel Target in Acute Myeloid Leukemia Academic Article
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Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors Academic Article
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Estrogen-Dependent Dynamic Profile of eNOS-DNA Associations in Prostate Cancer Academic Article
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Ethylenecarbodiimide-Fixed Donor Splenocyte Infusions Differentially Target Direct and Indirect Pathways of Allorecognition for Induction of Transplant Tolerance Academic Article
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Evasive Maneuvers by Secreted Bacterial Proteins to Avoid Innate Immune Responses Academic Article
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Evidence That the Epidermal Growth Factor Receptor on Host Cells Confers Reovirus Infection Efficiency Academic Article
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Evidence for P2-purinoceptors contribution in H2O2-induced contraction of rat aorta in the absence of endothelium Academic Article
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Evidence for a protective response by the gill proteome of rainbow trout exposed to X-ray induced bystander signals Academic Article
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Evidence for neuronal expression of functional Fc (ε and γ) receptors Academic Article
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Evidence for protein kinase involvement in the 5‐HT–[Ca2+]i–pannexin‐1 signalling pathway in type II glial cells of the rat carotid body Academic Article
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Evidence for the role of AMPK in regulating PGC‐1 alpha expression and mitochondrial proteins in mouse epididymal adipose tissue Academic Article
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Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differences Academic Article
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Exercise-induced Protein Arginine Methyltransferase Expression in Skeletal Muscle Academic Article
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Exercise‐stimulated interleukin‐15 is controlled by
AMPK
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Expanding Role of Dopaminergic Inhibition in Hypercapnic Responses of Cultured Rat Carotid Body Cells: Involvement of Type II Glial Cells Academic Article
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Expanding role of ATP as a versatile messenger at carotid and aortic body chemoreceptors Academic Article
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Exploration of trade-offs between steady-state and dynamic properties in signaling cycles Academic Article
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Exploring Pluripotency with Chemical Genetics Academic Article
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Expression of Multiple P2X Receptors by Glossopharyngeal Neurons Projecting to Rat Carotid Body O2-Chemoreceptors: Role in Nitric Oxide-Mediated Efferent Inhibition Academic Article
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Expression of P2X2 and P2X3 receptor subunits in rat carotid body afferent neurones: role in chemosensory signalling Academic Article
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Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3 Academic Article
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Expression of survivin and p16INK4a/Cdk6/pRB proteins and induction of apoptosis in response to radiation and cisplatin in meningioma cells Academic Article
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Expression of the β4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells Academic Article
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Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors Academic Article
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Extracellular DNA and histones: double‐edged swords in immunothrombosis Academic Article
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Extracellular matrix regulates human airway smooth muscle cell migration Academic Article
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Extrinsic signals determine myeloid-erythroid lineage switch in MN1 leukemia Academic Article
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FGF-Regulated Etv Genes Are Essential for Repressing Shh Expression in Mouse Limb Buds Academic Article
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Fc Gamma Receptor Signaling in Mast Cells Links Microbial Stimulation to Mucosal Immune Inflammation in the Intestine Academic Article
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Features of the Phosphatidylinositol Cycle and its Role in Signal Transduction Academic Article
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Fetal and Neonatal Exposure to Nicotine Disrupts Postnatal Lung Development in Rats: Role of VEGF and Its Receptors Academic Article
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Fetal growth interacts with multilocus genetic score reflecting dopamine signaling capacity to predict spontaneous sugar intake in children Academic Article
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Filamin A Regulates Monocyte Migration Through Rho Small GTPases During Osteoclastogenesis Academic Article
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FimH Adhesin of Type 1 Fimbriae Is a Potent Inducer of Innate Antimicrobial Responses Which Requires TLR4 and Type 1 Interferon Signalling Academic Article
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Fish oil supplementation suppresses resistance exercise and feeding-induced increases in anabolic signaling without affecting myofibrillar protein synthesis in young men Academic Article
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Fisiopatologia do transtorno afetivo bipolar: o que mudou nos últimos 10 anos? Academic Article
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Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues Academic Article
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FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells Academic Article
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Functional Redundancy of GSK-3α and GSK-3β in Wnt/β-Catenin Signaling Shown by Using an Allelic Series of Embryonic Stem Cell Lines Academic Article
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Functional genomic landscape of cancer-intrinsic evasion of killing by T cells Academic Article
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Functional impact of global rare copy number variation in autism spectrum disorders Academic Article
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Functional linkage as a direction for studies in oxidative stress: α-adrenergic receptorsThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease. Academic Article
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Fundamentals of Neurogastroenterology: Basic Science Academic Article
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Future Directions in the Treatment of Neuropathic Pain: A Review on Various Therapeutic Targets Academic Article
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G Protein-coupled Receptor Kinase-mediated Desensitization of Metabotropic Glutamate Receptor 1A Protects against Cell Death Academic Article
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G-Protein–Coupled Receptors as Signaling Targets for Antiplatelet Therapy Academic Article
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GLP-1R Agonists Modulate Enteric Immune Responses Through the Intestinal Intraepithelial Lymphocyte GLP-1R Academic Article
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GSK-3 is a master regulator of neural progenitor homeostasis Academic Article
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GSK-3: tricks of the trade for a multi-tasking kinase Academic Article
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GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in mice Academic Article
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GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia Academic Article
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GTP and guanosine synergistically enhance NGF-induced neurite outgrowth from PC12 cells Academic Article
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Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling Academic Article
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Genetic analysis of <i>vein</i> function in the <i>Drosophila</i> embryonic nervous system Academic Article
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Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model Academic Article
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Genome‐wideDNAmethylation changes with age in disease‐free human skeletal muscle Academic Article
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Genomic Minimalism in the Early Diverging Intestinal Parasite
Giardia lamblia Academic Article
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Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma Academic Article
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Germline variation in the insulin-like growth factor pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma Academic Article
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Gli3-mediated hedgehog inhibition in human pluripotent stem cells initiates and augments developmental programming of adult hematopoiesis Academic Article
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Glucocortiosteroid subsensitivity and asthma severity Academic Article
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Glucose‐regulated protein (
GRP78
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Glycogen Synthase Kinase 3α Deficiency Attenuates Atherosclerosis and Hepatic Steatosis in High Fat Diet–Fed Low Density Lipoprotein Receptor–Deficient Mice Academic Article
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Glycogen Synthase Kinase-3 - An Overview of An Over-Achieving Protein Kinase Academic Article
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Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells Academic Article
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Glycogen synthase kinase-3 in insulin and Wnt signalling: a double-edged sword? Academic Article
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Glycosyltransferases and Glycosaminoglycans in Bleomycin and Transforming Growth Factor-β1–Induced Pulmonary Fibrosis Academic Article
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Glypican LON-2 Is a Conserved Negative Regulator of BMP-like Signaling in Caenorhabditis elegans Academic Article
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Green tea catechins evoke a phasic contraction in rat aorta via H2O2-mediated multiple-signalling pathways Academic Article
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Guanosine 5´-O-(3-Thiotriphosphate) and Cations Regulate Melatonin Receptors, and Melatonin Inhibits Cyclic AMP Production in the Spinal Cord Academic Article
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Guanosine Inhibits CD40 Receptor Expression and Function Induced by Cytokines and β Amyloid in Mouse Microglia Cells Academic Article
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Guanosine Protects Glial Cells Against 6-Hydroxydopamine Toxicity Academic Article
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Guanosine promotes proliferation of neural stem cells through cAMP-CREB pathway. Academic Article
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Guidance signalling regulates leading edge behaviour during collective cell migration of cardiac cells in Drosophila Academic Article
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Gut Microbiota and Brain Function: An Evolving Field in Neuroscience: Table 1. Academic Article
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Gut commensal microvesicles reproduce parent bacterial signals to host immune and enteric nervous systems Academic Article
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H9724, a monoclonal antibody to Borrelia burgdorferi's flagellin, binds to heat shock protein 60 (HSP60) within live neuroblastoma cells: a potential role for HSP60 in peptide hormone signaling and in an autoimmune pathogenesis of the neuropathy of Lyme disease. Academic Article
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HB-EGF release mediates glucose-induced activation of the epidermal growth factor receptor in mesangial cells Academic Article
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HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants Academic Article
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HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner Academic Article
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HIV-1 gp120 Induces TLR2- and TLR4-Mediated Innate Immune Activation in Human Female Genital Epithelium Academic Article
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HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells Academic Article
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HSP90 modulates actin dynamics: Inhibition of HSP90 leads to decreased cell motility and impairs invasion Academic Article
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HUMAN PLATELET THROMBIN RECEPTORS Academic Article
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Haemopoietic processes in allergic disease: eosinophil/basophil development Academic Article
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Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling Academic Article
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Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration Academic Article
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Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia Academic Article
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Hematopoietic stem cell biology: too much of a Wnt thing Academic Article
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Heparin Inhibits Melatonin Binding and Signal Transduction in Chick Brain Academic Article
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Heparin Synergistically Enhances Interleukin-11 Signaling through Up-regulation of the MAPK Pathway Academic Article
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Hepatic Glucose Intolerance Precedes Hepatic Steatosis in the Male Aromatase Knockout (ArKO) Mouse Academic Article
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Herpes Simplex Virus 1 Tegument Protein US11 Downmodulates the RLR Signaling Pathway via Direct Interaction with RIG-I and MDA-5 Academic Article
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Herpes Simplex Virus Triggers and Then Disarms a Host Antiviral Response Academic Article
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Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells Academic Article
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High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells Academic Article
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High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus Academic Article
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High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells Academic Article
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High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2 Academic Article
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Histamine activates Cl- and K+ currents in guinea-pig tracheal myocytes: convergence with muscarinic signalling pathway. Academic Article
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Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy Academic Article
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History of bystander effects research 1905-present; what is in a name? Academic Article
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Host Defence Peptide LL-37 Induces IL-6 Expression in Human Bronchial Epithelial Cells by Activation of the NF-κB Signaling Pathway Academic Article
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Host Defense Peptide LL-37, in Synergy with Inflammatory Mediator IL-1β, Augments Immune Responses by Multiple Pathways Academic Article
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How Linear Tension Converts to Curvature: Geometric Control of Bone Tissue Growth Academic Article
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How is Mitochondrial Biogenesis Affected in Mitochondrial Disease? Academic Article
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Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia Academic Article
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Human Milk Oligosaccharides Protect against Necrotizing Enterocolitis by Activating Intestinal Cell Differentiation Academic Article
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Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells Academic Article
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Hydrogen peroxide is an endothelium-dependent contracting factor in rat renal artery Academic Article
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Hydrogen sulfide in the pathogenesis of atherosclerosis and its therapeutic potential Academic Article
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Hydrogen sulfide is a regulator of mammary gland development in prepubescent female mice Academic Article
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Hydroxychloroquine attenuates cigarette smoke induced autophagic signaling in the mouse ovary Academic Article
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Hyperinsulinemia-induced vascular smooth muscle cell (VSMC) migration and proliferation is mediated by converging mechanisms of mitochondrial dysfunction and oxidative stress Academic Article
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Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response Academic Article
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Hypoxia-Driven Immune Escape in the Tumor Microenvironment Academic Article
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Hypoxia-induced autophagy, epithelial to mesenchymal transition, and invasion in the pathophysiology of endometriosis: a perspective Academic Article
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Hypoxia-inducible factor-1α mediates the expression of mature β cell-disallowed genes in hypoxia-induced β cell dedifferentiation Academic Article
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IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity Academic Article
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IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro Academic Article
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II. The intestine as a sensory organ: neural, endocrine, and immune responses Academic Article
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IL-15 Can Signal via IL-15Rα, JNK, and NF-κB To Drive RANTES Production by Myeloid Cells Academic Article
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IL-15 and Type I Interferon Are Required for Activation of Tumoricidal NK Cells by Virus-Infected Dendritic Cells Academic Article
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IL-15 has innate anti-tumor activity independent of NK and CD8 T cells Academic Article
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IL-17 Receptor Signaling Inhibits C/EBPβ by Sequential Phosphorylation of the Regulatory 2 Domain Academic Article
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IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization Academic Article
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IL-4 and IL-13 Differentially Regulate TLR-Induced Eosinophil-Basophil Differentiation of Cord Blood CD34+ Progenitor Cells Academic Article
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IL-6 Induced STAT3 Signalling Is Associated with the Proliferation of Human Muscle Satellite Cells Following Acute Muscle Damage Academic Article
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IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages Academic Article
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IL‐25 promotes cisplatin resistance of lung cancer cells by activating NF‐κB signaling pathway to increase of major vault protein Academic Article
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Identification and Characterization of New Inhibitors of Fungal Homoserine Kinase Academic Article
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Identification of COUP-TFII as a peroxisome proliferator response element binding factor using genetic selection in yeast: COUP-TFII activates transcription in yeast but anatagonizes PPAR signaling in mammalian cells Academic Article
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Identification of Dp71 Isoforms in the Platelet Membrane Cytoskeleton Academic Article
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Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells Academic Article
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Identification of Synthetic Peptides that Inhibit Lipopolysaccharide (LPS) Binding to Myeloid Differentiation Protein-2 (MD-2) Academic Article
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Identification of a Novel Pathway Essential for the Immediate-Early, Interferon-Independent Antiviral Response to Enveloped Virions Academic Article
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Identification of early breast cancer patient cohorts who may benefit from lapatinib therapy Academic Article
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Identification of periplakin as a major regulator of lung injury and repair in mice Academic Article
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IgA potentiates NETosis in response to viral infection Academic Article
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Imaging Correlates of Molecular Signatures in Oligodendrogliomas Academic Article
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Immune Inhibitory Ligand CD200 Induction by TLRs and NLRs Limits Macrophage Activation to Protect the Host from Meningococcal Septicemia Academic Article
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Immunological Events Underlying the Induction of T Cell Non-Responsiveness Academic Article
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Immunometabolism of AMPK in insulin resistance and atherosclerosis Academic Article
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Immunometabolism of obesity and diabetes: microbiota link compartmentalized immunity in the gut to metabolic tissue inflammation Academic Article
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Impact of the menstrual cycle on peripheral vascular function in premenopausal women: systematic review and meta-analysis Academic Article
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Impaired Growth and Force Production in Skeletal Muscles of Young Partially Pancreatectomized Rats: A Model of Adolescent Type 1 Diabetic Myopathy? Academic Article
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Impaired c-src activation and motility defects in PEA3-null fibroblasts Academic Article
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Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis Academic Article
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In Vitro Selection of Structure‐Switching Signaling Aptamers Academic Article
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Increased FGF8 signaling promotes chondrogenic rather than osteogenic development in the embryonic skull Academic Article
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Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes Academic Article
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Increased Placental Apoptosis in Maternal Food Restricted Gestations: Role of the Fas Pathway Academic Article
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Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling Academic Article
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Induction of interleukin-10 and suppressor of cytokine signalling-3 gene expression following peptide immunotherapy Academic Article
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Inflammasomes in the lung Academic Article
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Inflammation in Obesity is a Common Link Between Defects in Fatty Acid Metabolism and Insulin Resistance Academic Article
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Inflammation promotes adipocyte lipolysis via IRE1 kinase Academic Article
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Inflammation, depression and cardiovascular disease in women: the role of the immune system across critical reproductive events Academic Article
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Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection Academic Article
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Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation Academic Article
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Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Academic Article
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Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin Academic Article
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Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice Academic Article
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Inhibition of TGF? signaling potentiates the FGF-2-induced stimulation of cardiomyocyte DNA synthesis Academic Article
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Inhibition of endogenous MTF-1 signaling in zebrafish embryos identifies novel roles for MTF-1 in development Academic Article
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Inhibition of sporulation, glycopeptide antibiotic production and resistance in Streptomyces toyocaensis NRRL 15009 by protein kinase inhibitors Academic Article
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Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin Academic Article
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Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain Academic Article
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Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions Academic Article
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Innate Immune Cytokines, Fibroblast Phenotypes, and Regulation of Extracellular Matrix in Lung Academic Article
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Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism Academic Article
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Innate and adaptive immunity against herpes simplex virus type 2 in the genital mucosa Academic Article
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Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions Academic Article
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Insulin Activates a p21-activated Kinase in Muscle Cells via Phosphatidylinositol 3-Kinase Academic Article
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Insulin Receptor Autophosphorylation and Signaling is Altered by Modulation of Membrane Physical Properties Academic Article
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Insulin signaling and limb-patterning: candidate pathways for the origin and evolutionary diversification of beetle ‘horns’ Academic Article
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Insulin signalling in mushroom body neurons regulates feeding behaviour inDrosophilalarvae Academic Article
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Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1 Academic Article
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Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response Academic Article
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Integrins Regulate Responsiveness to Slit Repellent Signals Academic Article
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Integrins are required for cardioblast polarisation in Drosophila Academic Article
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Interaction of Peptide Substrates of Fibroblast Collagenase with Divalent Cations: Ca2+ Binding by Substrate as a Suggested Recognition Signal for Collagenase Action Academic Article
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Interaction of c-Abl and p73α and their collaboration to induce apoptosis Academic Article
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Interferon Gamma in Successful Pregnancies1 Academic Article
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Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function Academic Article
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Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase Academic Article
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Interleukins 4 and 13 Increase Intestinal Epithelial Permeability by a Phosphatidylinositol 3-Kinase Pathway Academic Article
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Interplay of the Peroxisome Proliferator-activated Receptor and the Thyroid Hormone Receptor-signaling Pathways in Regulating Peroxisome Proliferator?responsive Genes Academic Article
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Intracellular Trafficking of CD23: Differential Regulation in Humans and Mice by Both Extracellular and Intracellular Exons Academic Article
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Intracellular signalling by nucleotide receptors in PC12 pheochromocytoma cells Academic Article
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Intrinsic pathway of apoptosis in peripheral blood eosinophils of Churg–Strauss syndrome Academic Article
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Investigation of FGFR2-IIIC Signaling via FGF-2 Ligand for Advancing GCT Stromal Cell Differentiation Academic Article
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Involvement of astrocytes in purine‐mediated reparative processes in the brain Academic Article
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Involvement of multiple sulfhydryl groups in melatonin signal transduction in chick brain Academic Article
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Involvement of the actin network in insulin signalling. Conference Paper
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Ionic mechanisms and Ca2+ handling in airway smooth muscle Academic Article
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Ionic mechanisms and Ca2+regulation in airway smooth muscle contraction: do the data contradict dogma? Academic Article
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Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells Academic Article
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Ionotropic Receptors in Pulmonary Neuroepithelial Bodies (NEB) and their Possible Role in Modulation of Hypoxia Signalling Academic Article
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Is there convergence in the molecular pathways underlying the repeated evolution of sociality in African cichlids? Academic Article
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Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca2+ handling and Rho/ROCK signaling Academic Article
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Isoprostanes and Lung Vascular Pathology Academic Article
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Isoprostanes constrict human radial artery by stimulation of thromboxane receptors, Ca2+ release, and RhoA activation Academic Article
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It’s Not Easy Being Blue: Are There Olfactory and Visual Trade-Offs in Plant Signalling? Academic Article
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Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells Academic Article
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Jnk1 activity lowers the cellular production of H2O2 and modulates the growth arrest response to scavenging of H2O2 by catalase Academic Article
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JunD/AP-1 Antagonizes the Induction of
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Just-in-time transcription program in metabolic pathways Academic Article
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Kaiso Represses the Cell Cycle Gene cyclin D1 via Sequence-Specific and Methyl-CpG-Dependent Mechanisms Academic Article
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Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells Academic Article
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Ketamine-induced neurotoxicity is mediated through endoplasmic reticulum stress in vitro in STHdhQ7/Q7 cells Academic Article
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Kinase-specific responsiveness to incremental contractile activity in skeletal muscle with low and high mitochondrial content Academic Article
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Largen: A Molecular Regulator of Mammalian Cell Size Control Academic Article
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Leptin Therapy Reverses Hyperglycemia in Mice With Streptozotocin-Induced Diabetes, Independent of Hepatic Leptin Signaling Academic Article
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Leucine supplementation is anti-atrophic during paradoxical sleep deprivation in rats Academic Article
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Leukemia inhibitory factor increases glucose uptake in mouse skeletal muscle Academic Article
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Leukotriene D4 receptors are not negatively coupled to adenylyl cyclase in guinea-pig lung parenchyma Academic Article
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Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women Academic Article
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Lipogenesis inhibitors: therapeutic opportunities and challenges Academic Article
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Local Regulation of Thyroid Hormone Signaling Chapter
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Long Double-Stranded RNA Induces an Antiviral Response Independent of IFN Regulatory Factor 3, IFN-β Promoter Stimulator 1, and IFN Academic Article
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Looks Who’s Talking Now Academic Article
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Loss of Hepatocyte-Nuclear-Factor-1α Impacts on Adult Mouse Intestinal Epithelial Cell Growth and Cell Lineages Differentiation Academic Article
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Loss of dystrophin expression in skeletal muscle is associated with senescence of macrophages and endothelial cells. Academic Article
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Loss-of-Function Mutations in MC4R Are Very Rare in the Greek Severely Obese Adult Population Academic Article
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Low Density Lipoprotein Receptor-Related Protein-2 Expression in Efferent Duct and Epididymal Epithelia: Evidence in Rats for its in Vivo Role in Endocytosis of Apolipoprotein J/Clusterin1 Academic Article
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Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men Academic Article
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Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer Academic Article
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Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis Academic Article
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Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) Academic Article
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Lysosomal and Proteasomal Degradation Play Distinct Roles in the Life Cycle of Cx43 in Gap Junctional Intercellular Communication-deficient and -competent Breast Tumor Cells Academic Article
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MAPping the kinase landscape of macrophage activation Academic Article
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MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial Trehalose Dimycolate and Mycobacterium tuberculosis Academic Article
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MD-1 is a Critical Part of the Mechanism Causing Th1-Cytokine-Triggered Murine Fetal Loss Syndrome Academic Article
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Macrophages Regulate Unilateral Ureteral Obstruction-Induced Renal Lymphangiogenesis through C-C Motif Chemokine Receptor 2–Dependent Phosphatidylinositol 3-Kinase-AKT–Mechanistic Target of Rapamycin Signaling and Hypoxia-Inducible Factor-1α/Vascular Endothelial Growth Factor-C Expression Academic Article
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Mammary glands exhibit molecular laterality and undergo left–right asymmetric ductal epithelial growth in MMTV-cNeu mice* Academic Article
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Maternal Nicotine Exposure Leads to Impaired Disulfide Bond Formation and Augmented Endoplasmic Reticulum Stress in the Rat Placenta Academic Article
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Maternal nutrient restriction impairs young adult offspring ovarian signaling resulting in reproductive dysfunction and follicle loss† Academic Article
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Mathematical model for chemotherapeutic drug efficacy in arresting tumour growth based on the cancer stem cell hypothesis Academic Article
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Mathematical model for the cancer stem cell hypothesis Academic Article
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Mathematical model of the role of intercellular signalling in intercellular cooperation during tumorigenesis Academic Article
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Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis Academic Article
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Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer. Academic Article
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Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through β-catenin signaling Academic Article
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Matters of taste: bridging molecular physiology and the humanities Academic Article
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Mechanical Strain-Induced RhoA Activation Requires NADPH Oxidase-Mediated ROS Generation in Caveolae Academic Article
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Mechanical Stretch-Induced Signal Transduction in Cultured Mesangial Cells Academic Article
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Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis Conference Paper
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Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK Academic Article
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Mechanisms Employed by Herpes Simplex Virus 1 to Inhibit the Interferon Response Academic Article
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Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma Academic Article
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Mechanisms associated with mitochondrial-generated reactive oxygen species in cancerThis article is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease. Academic Article
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Mechanisms of Cardiovascular Toxicity of BCR-ABL1 Tyrosine Kinase Inhibitors in Chronic Myelogenous Leukemia Academic Article
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Mechanisms of exercise‐induced survival motor neuron expression in the skeletal muscle of spinal muscular atrophy‐like mice Academic Article
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Mechanisms of innate immune activation by gluten peptide p31-43 in mice Academic Article
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Medulloblastoma stem cells: Modeling tumor heterogeneity Academic Article
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Medulloblastoma stem cells: where development and cancer cross pathways Academic Article
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Melatonin and Hippo Pathway: Is There Existing Cross-Talk? Academic Article
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Melatonin—A pleiotropic, orchestrating regulator molecule Academic Article
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Membrane components can modulate the substrate specificity of protein kinase C Academic Article
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Membrane shape as determinant of protein properties Academic Article
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Mesangial cell signaling cascades in response to mechanical strain and glucose Academic Article
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Metabolic Syndrome and Acute Hyperglycemia Are Associated With Endoplasmic Reticulum Stress in Human Mononuclear Cells Academic Article
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Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment Academic Article
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Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC Academic Article
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Metformin: Metabolic Rewiring Faces Tumor Heterogeneity Academic Article
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Methylation-dependent regulation of hypoxia inducible factor-1 alpha gene expression by the transcription factor Kaiso Academic Article
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Mice with a Targeted Mutation of
Patched2
Are Viable but Develop Alopecia and Epidermal Hyperplasia Academic Article
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MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity Academic Article
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MicroRNAs as Key Effectors in the p53 Network Academic Article
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MicroRNAs: Non-coding fine tuners of receptor tyrosine kinase signalling in cancer Academic Article
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Microvesicles Contribute to the Bystander Effect of DNA Damage Academic Article
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Mind the gap: Signal movement through plasmodesmata is critical for the manifestation of SAR Academic Article
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Mitochondrial Proteins at Unexpected Cellular Locations: Export of Proteins from Mitochondria from an Evolutionary Perspective Academic Article
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Mitochondrial contributions to cancer cell physiology: potential for drug development Academic Article
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Mitochondrial dysfunction is associated with a pro-apoptotic cellular environment in senescent cardiac muscle Academic Article
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Modifying the Organ Matrix Pre-engraftment: A New Transplant Paradigm? Academic Article
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Modular pharmacology-based approach to identify hub genes and kernel pathways of taodan granules treated psoriasis Academic Article
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Modularity of protein function: Chimeric interleukin 1.beta.s containing specific protease inhibitor loops retain function of both molecules Academic Article
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Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis Academic Article
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Modulation of Hepatic Granulomatous Responses by Transgene Expression of DAP12 or TREM-1-Ig Molecules Academic Article
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Modulation of Human Airway Smooth Muscle Migration by Lipid Mediators and Th-2 Cytokines Academic Article
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Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication Academic Article
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Modulation of autophagy signaling with resistance exercise and protein ingestion following short-term energy deficit Academic Article
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Modulation of insulin action by vanadate: evidence of a role for phosphotyrosine phosphatase activity to alter cellular signaling Academic Article
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Modulation of oxidative phosphorylation (OXPHOS) by radiation- induced biophotons Academic Article
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Molecular Genetic Analysis of the Idd4 Locus Implicates the IFN Response in Type 1 Diabetes Susceptibility in Nonobese Diabetic Mice Academic Article
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Molecular Mechanisms Linking Diabetes to the Accelerated Development of Atherosclerosis Academic Article
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Molecular Pathways: Epigenetic Modulation of Wnt–Glycogen Synthase Kinase-3 Signaling to Target Human Cancer Stem Cells Academic Article
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Molecular Pathways: Leveraging the BCL-2 Interactome to Kill Cancer Cells—Mitochondrial Outer Membrane Permeabilization and Beyond Academic Article
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Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States Academic Article
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Molecular and Histological Analysis of a New Rat Model of Experimental Knee Osteoarthritis Conference Paper
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Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice Academic Article
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Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis Academic Article
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Molecules in focus Transforming growth factor-beta (TGF-β) Academic Article
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Monocytic Differentiation of Acute Promyelocytic Leukemia Cells in Response to 1,25-Dihydroxyvitamin D3 Is Independent of Nuclear Receptor Binding Academic Article
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Mood and gut feelings Academic Article
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Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15 Academic Article
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Multifactorial Regulation of Prostaglandin Synthesis in Preovulatory Goldfish Ovarian Follicles1 Academic Article
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Multiple Signaling Pathways Control the Activation of the CEF-4/9E3 Cytokine Gene by pp60v- Academic Article
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Multiple histidines in the periplasmic domain of theSalmonella entericasensor kinase SsrA enhance signaling in response to extracellular acidification Academic Article
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Multitargeted anti-angiogenic agents and NSCLC: Clinical update and future directions Academic Article
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Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells Academic Article
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Muscarinic acetylcholine receptor activation increases transcellular transport of macromolecules across mouse and human intestinal epitheliumin vitro Academic Article
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Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition Academic Article
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Mutations in TBCK, Encoding TBC1-Domain-Containing Kinase, Lead to a Recognizable Syndrome of Intellectual Disability and Hypotonia Academic Article
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Mutations inCaenorhabditis briggsaeidentify new genes important for limiting the response to EGF signaling during vulval development Academic Article
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Myelin-Associated Glycoprotein Is a Myelin Signal that Modulates the Caliber of Myelinated Axons Academic Article
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Myostatin inhibition therapy for insulin-deficient type 1 diabetes Academic Article
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Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts Academic Article
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N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation Academic Article
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NME4/nucleoside diphosphate kinase D in cardiolipin signaling and mitophagy Academic Article
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NOD1 Activators Link Innate Immunity to Insulin Resistance Academic Article
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NRAGE, A Novel MAGE Protein, Interacts with the p75 Neurotrophin Receptor and Facilitates Nerve Growth Factor–Dependent Apoptosis Academic Article
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NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway Academic Article
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Naphthenic Acid Mixtures from Oil Sands Process-Affected Water Enhance Differentiation of Mouse Embryonic Stem Cells and Affect Development of the Heart Academic Article
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Nerve growth factor treatment alters Ca2+ pump levels in PC12 cells Academic Article
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Neuroimmunologic and Neurotrophic Interactions in Autism Spectrum Disorders: Relationship to Neuroinflammation Academic Article
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Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line Academic Article
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Neutralization of LPS or blockage of TLR4 signaling prevents stress-triggered fetal loss in murine pregnancy Academic Article
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Neutrons do not produce a bystander effect in zebrafish irradiated in vivo Academic Article
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New therapeutic strategies to treat human cancers expressing mutant p53 proteins Academic Article
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New treatment and markers of prognosis for idiopathic pulmonary fibrosis: lessons learned from translational research Academic Article
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Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells Academic Article
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Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells Academic Article
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Nitric oxide, human diseases and the herbal products that affect the nitric oxide signalling pathway Academic Article
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Nitric oxide-dependent changes in Schistosoma mansoni gene expression Academic Article
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Non-Canonical Allostery in Cyclic Nucleotide Dependent Kinases Academic Article
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Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin Academic Article
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Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota Academic Article
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Noncanonical Wnt Signaling Orchestrates Early Developmental Events toward Hematopoietic Cell Fate from Human Embryonic Stem Cells Academic Article
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Nonendothelial Aortic Source of Nitric Oxide in Wistar-Kyoto Normotensive and Spontaneous Hypertensive Rats Academic Article
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Nonhematopoietic cells represent a more rational target of in vivo hedgehog signaling affecting normal or acute myeloid leukemia progenitors Academic Article
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Normal and defective pathways in biogenesis and maintenance of the insulin storage pool Academic Article
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Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma Academic Article
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Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells Academic Article
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Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells Academic Article
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Novel paradigms of innate immune sensing of viral infections Academic Article
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Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells Academic Article
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Nuclear import of the BTB/POZ transcriptional regulator Kaiso Academic Article
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Nutrient Sensing and Response Drive Developmental Progression in
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Nutrient provision increases signalling and protein synthesis in human skeletal muscle after repeated sprints Academic Article
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O-GlcNAc-glycosylation of β-catenin regulates its nuclear localization and transcriptional activity Academic Article
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ORIGINAL ARTICLE: LPS-Induced Murine Abortions Require C5 but not C3, and are Prevented by Upregulating Expression of the CD200 Tolerance Signaling Molecule Academic Article
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Obstacles to effective Toll-like receptor agonist therapy for hematologic malignancies Academic Article
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Oncogenes belonging to the CSF-1 transduction pathway direct p53 tumor suppressor effects to monocytic differentiation in 32D cells Academic Article
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Oncolytic bovine herpesvirus type 1 infects and kills breast tumor cells and breast cancer-initiating cells irrespective of tumor subtype Academic Article
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Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: Regulation of the type-II IL-4 receptor chains IL-4Rα and IL-13Rα1 Academic Article
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Oncostatin M Regulates Eotaxin Expression in Fibroblasts and Eosinophilic Inflammation in C57BL/6 Mice Academic Article
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Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells Academic Article
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Oncostatin M induction of eotaxin-1 expression requires the convergence of PI3′K and ERK1/2 MAPK signal transduction pathways Academic Article
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Oncostatin M-Induced IL-6 Expression in Murine Fibroblasts Requires the Activation of Protein Kinase Cδ Academic Article
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Ontogeny of O2 and CO2//H+ chemosensitivity in adrenal chromaffin cells: role of innervation Academic Article
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Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma Academic Article
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Opposing effects of IL-1β/COX-2/PGE2 pathway loop on islets in type 2 diabetes mellitus Academic Article
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Overexpression of the Endoplasmic Reticulum 60 Protein ER-60 Downregulates ApoB100 Secretion by Inducing Its Intracellular Degradation via a Nonproteasomal Pathway: Evidence for an ER-60-Mediated and pCMB-Sensitive Intracellular Degradative Pathway Academic Article
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Oxidative stress and Nrf2 signaling in McArdle disease Academic Article
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Oxygen sensing in airway chemoreceptors Academic Article
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Oxytocin down-regulates mesenteric afferent sensitivity via the enteric OTR/nNOS/NO/KATPpathway in rat Academic Article
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Oxytocin hyperpolarizes cultured duodenum myenteric intrinsic primary afferent neurons by opening BK
Ca
channels through IP
3
pathway Academic Article
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P2Y2 Receptor Up-Regulation Induced by Guanosine or UTP in Rat Brain Cultured Astrocytes Academic Article
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PDZK1 in leukocytes protects against cellular apoptosis and necrotic core development in atherosclerotic plaques in high fat diet fed ldl receptor deficient mice Academic Article
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PIKfyve: a new fish in the growing pool of AMPK substrates Academic Article
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PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells Academic Article
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PPAR ligands decrease human airway smooth muscle cell migration and extracellular matrix synthesis Academic Article
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PRY-1/Axin signaling regulates lipid metabolism in Caenorhabditis elegans Academic Article
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Packing on the Pounds in Response to Bacterial Growth Conditions Academic Article
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Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans Academic Article
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Pan-urologic cancer genomic subtypes that transcend tissue of origin Academic Article
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Panax notoginseng saponin is superior to aspirin in inhibiting platelet adhesion to injured endothelial cells through COX pathway in vitro Academic Article
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Panax quinquefolium saponin combined with dual antiplatelet drugs inhibits platelet adhesion to injured HUVECs via PI3K/AKT and COX pathways Academic Article
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Parallel multi-time point cell stimulation and lysis on-chip for studying early signaling events in T cell activation Academic Article
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Pathway Pathology Academic Article
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Pea3 Transcription Factors and Wnt1-Induced Mouse Mammary Neoplasia Academic Article
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Peptide hormones, neurotransmitters, and drugs as Ca2+ ionophores: implications for signal transduction Academic Article
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Perinatal Administration of a Selective Serotonin Reuptake Inhibitor Induces Impairments in Reproductive Function and Follicular Dynamics in Female Rat Offspring Academic Article
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Perioperative cardiovascular system failure in South Asians undergoing cardiopulmonary bypass is associated with prolonged inflammation and increased Toll-like receptor signaling in inflammatory monocytes Academic Article
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Peripheral Blood Gene Expression Changes during Allergen Inhalation Challenge in Atopic Asthmatic Individuals Academic Article
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Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis Academic Article
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Perturbations to Homeostasis in Experimental Models Revealed Innate Pathways Driving Food Allergy Academic Article
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Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer Academic Article
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Phosphatidylinositol 3-Kinase (PI3K) Signaling via Glycogen Synthase Kinase-3 (Gsk-3) Regulates DNA Methylation of Imprinted Loci Academic Article
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Phosphoinositide 3-kinase inhibitors in advanced breast cancer: A systematic review and meta-analysis Academic Article
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Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional Activity Academic Article
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Placental Trophoblast from Successful Human Pregnancies Expresses the Tolerance Signaling Molecule, CD200 (OX-2)* Academic Article
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Plasticity of Skeletal Muscle Mitochondria in Response to Contractile Activity Academic Article
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Pleiotropic actions of factor Xa inhibition in cardiovascular prevention: mechanistic insights and implications for anti-thrombotic treatment Academic Article
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Pleiotropic roles of Notch signaling in normal, malignant, and developmental hematopoiesis in the human Academic Article
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Polymorphism in the Innate Immune Receptor SIRPα Controls CD47 Binding and Autoimmunity in the Nonobese Diabetic Mouse Academic Article
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Pramanicin Analog Induces Apoptosis in Human Colon Cancer Cells: Critical Roles for Bcl-2, Bim, and p38 MAPK Signaling Academic Article
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Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis Academic Article
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Prolonged moderate-intensity aerobic exercise does not alter apoptotic signaling and DNA fragmentation in human skeletal muscle Academic Article
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Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation Academic Article
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Protean effects of a natural peptide agonist of the G protein-coupled secretin receptor demonstrated by receptor mutagenesis. Academic Article
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Protective activity of guanosine in an in vitro model of Parkinson's disease. Academic Article
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Protein Ingestion Increases Myofibrillar Protein Synthesis after Concurrent Exercise Academic Article
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Protein arginine methyltransferase expression, localization, and activity during disuse-induced skeletal muscle plasticity Academic Article
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Protein kinase C α modulates liver X receptor α transactivation Academic Article
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Protein kinase Cα negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor Academic Article
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Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation Academic Article
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Proteins and cholesterol-rich domains Academic Article
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Proteolytic Cleavage of Chemerin Protein Is Necessary for Activation to the Active Form, Chem157S, Which Functions as a Signaling Molecule in Glioblastoma Academic Article
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Proteomic changes in the gills of wild-type and transgenic radiosensitive medaka following exposure to direct irradiation and to X-ray induced bystander signals Academic Article
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Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways Academic Article
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Psychosis pathways converge via D2High dopamine receptors Academic Article
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Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells Academic Article
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Purification and characterization of VanR and the cytosolic domain of VanS: A two-component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147 Academic Article
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Purine and pyrimidine nucleotides activate distinct signalling pathways in PC12 cells Academic Article
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Purinergic Pathways in the Spinal Microglia as a Putative Target for Treatment of Chronic Abdominal Pain Academic Article
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Pyruvate Is Synthesized by Two Pathways in Pea Bacteroids with Different Efficiencies for Nitrogen Fixation Academic Article
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Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells Academic Article
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Quorum sensing in
Escherichia coli
,
Salmonella typhimurium
, and
Vibrio harveyi
: A new family of genes responsible for autoinducer production Academic Article
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Quorum sensing in
Escherichia coli
and
Salmonella typhimurium Academic Article
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R-spondin1 Is a High Affinity Ligand for LRP6 and Induces LRP6 Phosphorylation and β-Catenin Signaling Academic Article
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RIPK2 Dictates Insulin Responses to Tyrosine Kinase Inhibitors in Obese Male Mice Academic Article
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Radiation and the regulatory landscape of neo2-Darwinism Academic Article
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Radiation-Induced Bystander and other Non-Targeted Effects: Novel Intervention Points in Cancer Therapy? Academic Article
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Radiation-induced bystander effects — implications for cancer Academic Article
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Radiosensitization of glioma cells by modulation of Met signalling with the hepatocyte growth factor neutralizing antibody, AMG102 Academic Article
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Radiotherapy and the potential exploitation of bystander effects Academic Article
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Rapamycin does not prevent increases in myofibrillar or mitochondrial protein synthesis following endurance exercise Academic Article
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Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insulin Signaling Academic Article
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Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise Academic Article
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Reactive oxygen species from mitochondria impacts trophoblast fusion and the production of endocrine hormones by syncytiotrophoblasts Academic Article
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Recent advances in understanding viral evasion of type I interferon Academic Article
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Recent insights into neuromuscular junction biology in Duchenne muscular dystrophy: Impacts, challenges, and opportunities Academic Article
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Receptor Subunit-specific Action of Oncostatin M in Hepatic Cells and Its Modulation by Leukemia Inhibitory Factor Academic Article
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Receptor domains of two-component signal transduction systems Academic Article
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Receptor-interacting protein 140 interacts with and inhibits transactivation by, peroxisome proliferator-activated receptor α and liver-X-receptor α Academic Article
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Receptor-mediated protein kinase activation and the mechanism of transmembrane signaling in bacterial chemotaxis Academic Article
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Receptors and signaling pathway underlying relaxations to isoprostanes in canine and porcine airway smooth muscle Academic Article
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Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity Academic Article
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Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression Academic Article
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Reduced carbohydrate availability enhances exercise-induced p53 signaling in human skeletal muscle: implications for mitochondrial biogenesis Academic Article
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Regulation of Acidification and Apoptosis by SHP-1 and Bcl-2 Academic Article
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Regulation of Eosinophilia in Asthma—New Therapeutic Approaches for Asthma Treatment Academic Article
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Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M Academic Article
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Regulation of Mitochondrial Biogenesis in Muscle by Endurance Exercise Academic Article
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Regulation of Myogenic Differentiation by Androgens: Cross Talk between Androgen Receptor/ β-Catenin and Follistatin/Transforming Growth Factor-β Signaling Pathways Academic Article
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Regulation of Rho/ROCK signaling in airway smooth muscle by membrane potential and [Ca2+]i Academic Article
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Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways Academic Article
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Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain Academic Article
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Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3 Academic Article
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Regulation of a muralytic enzyme-encoding gene by two non-coding RNAs Academic Article
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Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli. Academic Article
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Regulation of gene expression in oncogenically transformed cells Academic Article
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Regulation of glucose transporter 4 traffic by energy deprivation from mitochondrial compromise Academic Article
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Regulation of plasminogen activator inhibitor-1 secretion by growth factors in smooth muscle cells Academic Article
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Regulation of plasminogen activator inhibitor-1 secretion by urokinase and tissue plasminogen activator in rat epithelioid-type smooth muscle cells Academic Article
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Regulation of signal transducer, gp130 and the lif receptor in acute inflammation in vivo Academic Article
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Regulation of slow wave frequency by IP3-sensitive calcium release in the murine small intestine Academic Article
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Regulation of the proline regulatory axis and autophagy modulates stemness in TP73/p73 deficient cancer stem-like cells Academic Article
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Regulation of the water channel aquaporin-1: isolation and reconstitution of the regulatory complex Academic Article
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Regulatory properties of neuronal cdc2-like kinase Academic Article
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Relaxin alters cardiac myofilament function through a PKC-dependent pathway Academic Article
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Release of Neutrophil Extracellular Traps by Neutrophils Stimulated With Antiphospholipid Antibodies: A Newly Identified Mechanism of Thrombosis in the Antiphospholipid Syndrome Academic Article
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Repellent Signaling by Slit Requires the Leucine-Rich Repeats Academic Article
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Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis Academic Article
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Resistance exercise decreases eIF2Bε phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men Academic Article
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Resistance exercise enhances mTOR and MAPK signalling in human muscle over that seen at rest after bolus protein ingestion Academic Article
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Resistance exercise load does not determine training-mediated hypertrophic gains in young men Academic Article
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Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men Academic Article
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Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men Academic Article
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Resistance training minimizes catabolic effects induced by sleep deprivation in rats Academic Article
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Response regulator output in bacterial chemotaxis Academic Article
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Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis Academic Article
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Revisiting Type 2-high and Type 2-low airway inflammation in asthma: current knowledge and therapeutic implications Academic Article
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Role of DAP12 in Innate and Adaptive Immune Responses Academic Article
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Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC) Academic Article
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Role of Ets transcription factors in mammary gland development and oncogenesis. Academic Article
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Role of Sarcoplasmic Reticulum in the Contractile Function of Vascular Smooth Muscle as Studied by 2,5-Di-(Tert-Butyl)-1,4-Benzohydroquinone Academic Article
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Role of Serum Amyloid A as an Intermediate in the IL-1 and PMA-Stimulated Signaling Pathways Regulating Expression of Rabbit Fibroblast Collagenase Academic Article
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Role of bisphenol A on calcium influx and its potential toxicity on the testis of Danio rerio Academic Article
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Role of glycoprotein IIa (beta 1 subunit of very late activation antigens) in platelet functions Academic Article
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Role of inflammation in the pathogenesis of atherosclerosis and therapeutic interventions Academic Article
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Role of serotonergic neurons in the Drosophila larval response to light Academic Article
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Role of the COX2-PGE2 axis in S. pneumoniae-induced exacerbation of experimental fibrosis Academic Article
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Role of the actin cytoskeleton in insulin action Academic Article
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Role of α-Helical Coiled-coil Interactions in Receptor Dimerization, Signaling, and Adaptation during Bacterial Chemotaxis Academic Article
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Roles for VEGF‐C/NRP–2 axis in regulating renal tubular epithelial cell survival and autophagy during serum deprivation Academic Article
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Roles of specific lipid species in the cell and their molecular mechanism Academic Article
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SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells Academic Article
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SBDS-deficient cells undergo accelerated apoptosis through the Fas-pathway Academic Article
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SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells Academic Article
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SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction Academic Article
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SREBP-1 activation by glucose mediates TGF-β upregulation in mesangial cells Academic Article
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SREBP-1 is a novel mediator of TGFβ1 signaling in mesangial cells Academic Article
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STAT-6 Is an Absolute Requirement for Murine Rejection of Hymenolepis diminuta Academic Article
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Saikosaponin d downregulates microRNA-155 and upregulates FGF2 to improve depression-like behaviors in rats induced by unpredictable chronic mild stress by negatively regulating NF-κB Academic Article
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Salicylate enhances the response of prostate cancer to radiotherapy Academic Article
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Salmonella Pathogenicity Island 2 Is Expressed Prior
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SapB and the chaplins: connections between morphogenetic proteins in Streptomyces coelicolor Academic Article
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Selective involvement of the PI3K/PKB/bad pathway in retinal cell death Academic Article
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Semaphorin 3F Antagonizes Neurotrophin-Induced Phosphatidylinositol 3-Kinase and Mitogen-Activated Protein Kinase Kinase Signaling: A Mechanism for Growth Cone Collapse Academic Article
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Sensitization of G Protein-Coupled Benzodiazepine Receptors in the Striatum of 6-Hydroxydopamine-Lesioned Rats Academic Article
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Separate roles of IL-6 and oncostatin M in mouse macrophage polarizationin vitroandin vivo Academic Article
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Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts Academic Article
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Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells Academic Article
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Shear flow-induced motility ofDictyostelium discoideumcells on solid substrate Academic Article
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Signal processing at mammalian carotid body chemoreceptors Academic Article
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Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells Academic Article
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Signal transduction in bacterial chemotaxis. Academic Article
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Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK Academic Article
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Specific CD45 isoforms differentially regulate T cell receptor signaling. Academic Article
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Sphingosine-1-Phosphate Receptor 1, Expressed in Myeloid Cells, Slows Diet-Induced Atherosclerosis and Protects against Macrophage Apoptosis in Ldlr KO Mice Academic Article
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Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase Academic Article
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Stat6 dependent goblet cell hyperplasia during intestinal nematode infection Academic Article
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Sterol Regulatory Element Binding Protein (SREBP)-1 is a novel regulator of the Transforming Growth Factor (TGF)-β receptor I (TβRI) through exosomal secretion Academic Article
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Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Academic Article
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Stimulatory and inhibitory signaling molecules that regulate renal branching morphogenesis Academic Article
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Streptomyces exploration is triggered by fungal interactions and volatile signals Academic Article
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Stress neuropeptides evoke epithelial responses via mast cell activation in the rat colon Academic Article
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Stress-responsive signal transduction mechanisms in glomerular cells Academic Article
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Stretch activation of Jun N-terminal kinase/stress-activated protein kinase in mesangial cells Academic Article
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Stretch-induced Activation of Transforming Growth Factor-β1 in Pulmonary Fibrosis Academic Article
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Stretch-induced Raf-1 activation in mesangial cells requires actin cytoskeletal integrity Academic Article
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Stromal β-catenin overexpression contributes to the pathogenesis of renal dysplasia Academic Article
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Stromally Expressed β-Catenin Modulates Wnt9b Signaling in the Ureteric Epithelium Academic Article
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Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases Academic Article
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Structures and Solution Properties of Two Novel Periplasmic Sensor Domains with c-Type Heme from Chemotaxis Proteins of Geobacter sulfurreducens: Implications for Signal Transduction Academic Article
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Subgroup-specific structural variation across 1,000 medulloblastoma genomes Academic Article
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Substance P activates Cl− and K+ conductances in guinea-pig tracheal smooth muscle cells Academic Article
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Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability Academic Article
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Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity Academic Article
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Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo Academic Article
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Swelling‐induced chloride current in glioblastoma proliferation, migration, and invasion Academic Article
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Synapse Formation and Hypoxic Signalling in Co-Cultures of Rat Petrosal Neurones and Carotid Body Type 1 Cells Academic Article
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Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis Academic Article
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Synergy in Induction of Increased Renal Allograft Survival after Portal Vein Infusion of Dendritic Cells Transduced to Express TGFβ and IL-10, along with Administration of CHO Cells Expressing the Regulatory Molecule OX-2 Academic Article
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Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits Academic Article
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Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways Academic Article
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Systemic acquired resistance networks amplify airborne defense cues Academic Article
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T cell-mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells Academic Article
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TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells Academic Article
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TGF- receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung Academic Article
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TGF-β and Smad3 Signaling Link Inflammation to Chronic Fibrogenesis Academic Article
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TGFβ receptor I transactivation mediates stretch-induced Pak1 activation and CTGF upregulation in mesangial cells Academic Article
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TLR2 Plays a Pivotal Role in Mediating Mucosal Serotonin Production in the Gut Academic Article
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TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathway Academic Article
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TNF-α is a critical negative regulator of type 1 immune activation during intracellular bacterial infection Academic Article
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TRIM33 prevents pulmonary fibrosis by impairing TGF-β1 signalling Academic Article
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Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR Academic Article
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Targeting AMP-activated protein kinase (AMPK) for treatment of autosomal dominant polycystic kidney disease Academic Article
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Targeting C3a/C5a receptors inhibits human mesangial cell proliferation and alleviates immunoglobulin A nephropathy in mice Academic Article
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Targeting Genes for Treatment in Idiopathic Pulmonary Fibrosis: Challenges and Opportunities, Promises and Pitfalls Academic Article
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Targeting Myelin to Optimize Plasticity of Spared Spinal Axons Academic Article
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Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology Academic Article
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Targeting apoptosis: preclinical and early clinical experience with mapatumumab, an agonist monoclonal antibody targeting TRAIL-R1 Academic Article
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Telomerase Mediates Vascular Endothelial Growth Factor-dependent Responsiveness in a Rat Model of Hind Limb Ischemia Academic Article
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Temtamy Preaxial Brachydactyly Syndrome Is Caused by Loss-of-Function Mutations in Chondroitin Synthase 1, a Potential Target of BMP Signaling Academic Article
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Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors. Academic Article
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Testosterone inhibits transforming growth factor-β signaling during myogenic differentiation and proliferation of mouse satellite cells: Potential role of follistatin in mediating testosterone action Academic Article
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Thaxtomin A-deficient endophytic Streptomyces sp. enhances plant disease resistance to pathogenic Streptomyces scabies Academic Article
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The Antibiotic Resistome: A Guide for the Discovery of Natural Products as Antimicrobial Agents Academic Article
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The CD200 tolerance-signaling molecule and its receptor, CD200R1, are expressed in human placental villus trophoblast and in peri-implant decidua by 5 weeks’ gestation Academic Article
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The Circadian Clock Gene, Bmal1, Regulates Intestinal Stem Cell Signaling and Represses Tumor Initiation Academic Article
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The Cleaved Peptide of PAR1 Results in a Redistribution of the Platelet Surface GPIb-IX-V Complex to the Surface-Connected Canalicular System Academic Article
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The Effects of Leptin on Airway Smooth Muscle Responses Academic Article
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The GRHL2/ZEB Feedback Loop-A Key Axis in the Regulation of EMT in Breast Cancer Academic Article
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The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma Academic Article
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The Gastrin-Releasing Peptide Receptor as a Therapeutic Target in Central Nervous System Disorders Academic Article
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The Herpes Simplex Virus 1-Encoded Envelope Glycoprotein B Activates NF-κB through the Toll-Like Receptor 2 and MyD88/TRAF6-Dependent Signaling Pathway Academic Article
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The Hippo Tumor Suppressor Pathway: A Brainstorming WorkshopA report on the research meeting “The Hippo Tumor Suppressor Pathway: A Brainstorming Workshop” sponsored mainly by the Regina Elena Cancer Center and the Nicola Foundation and held in Rome, Italy, on 22 and 23 April 2009. Academic Article
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The Hippo tumor suppressor pathway: a report on ‘the second workshop on the Hippo tumor suppressor pathway’ Academic Article
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The Human Microbiota in Multiple Myeloma and Proteasome Inhibitors Academic Article
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The Imprinted Gene Neuronatin
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The Influence of Cigarette Smoking on Viral Infections Academic Article
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The Involvement of Calcium and MAP Kinase Signaling Pathways in the Production of Radiation-Induced Bystander Effects Academic Article
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The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule Academic Article
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The Methyltransferase Smyd1 Mediates LPS-Triggered Up-Regulation of IL-6 in Endothelial Cells Academic Article
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The NK Receptor NKp30 Mediates Direct Fungal Recognition and Killing and Is Diminished in NK Cells from HIV-Infected Patients Academic Article
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The Nitric Oxide Pathway Provides Innate Antiviral Protection in Conjunction with the Type I Interferon Pathway in Fibroblasts Academic Article
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The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm Academic Article
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The Order of Exercise during Concurrent Training for Rehabilitation Does Not Alter Acute Genetic Expression, Mitochondrial Enzyme Activity or Improvements in Muscle Function Academic Article
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The Orphan Nuclear Hormone Receptor LXRα Interacts with the Peroxisome Proliferator-activated Receptor and Inhibits Peroxisome Proliferator Signaling Academic Article
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The P2Y6 Receptor Mediates Clostridium difficile Toxin-Induced CXCL8/IL-8 Production and Intestinal Epithelial Barrier Dysfunction Academic Article
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The POZ-ZF Transcription Factor Kaiso (ZBTB33) Induces Inflammation and Progenitor Cell Differentiation in the Murine Intestine Academic Article
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The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-β Oligomer Toxicity Academic Article
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The Pulmonary Biology of Isoprostanes Academic Article
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The RING‐finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling inDrosophila Academic Article
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The Role of Dietary Fat throughout the Prostate Cancer Trajectory Academic Article
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The Role of Endoplasmic Reticulum Stress-Glycogen Synthase Kinase-3 Signaling in Atherogenesis Academic Article
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The Role of Serotonin in Breast Cancer Stem Cells Academic Article
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The Role of the TL1A/DR3 Axis in the Activation of Group 2 Innate Lymphoid Cells in Subjects with Eosinophilic Asthma Academic Article
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The Suppressor of Cytokine Signaling 3 Inhibits Leptin Activation of AMP-Kinase in Cultured Skeletal Muscle of Obese Humans Academic Article
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The Trophic Effects of Purines and Purinergic Signaling in Pathologic Reactions of Astrocytes Academic Article
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The YebC Family Protein PA0964 Negatively Regulates the
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The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades. Academic Article
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The acute phase response of the liver in inflammation. Academic Article
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The common inflammatory etiology of depression and cognitive impairment: a therapeutic target Academic Article
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The complex roles of STAT3 and STAT5 in maintaining redox balance: Lessons from STAT-mediated xCT expression in cancer cells Academic Article
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The control of testicular androgen production in the goldfish: Effects of activators of different intracellular signalling pathways Academic Article
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The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo Academic Article
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The dynamic microbe: green fluorescent protein brings bacteria to light Academic Article
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The effect of montelukast, budesonide alone, and in combination on exercise-induced bronchoconstriction Academic Article
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The effect of smoking cessation pharmacotherapies on pancreatic beta cell function Academic Article
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The fate of released histamine: reception, response and termination. Conference Paper
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The fight between the teleost fish immune response and aquatic viruses Academic Article
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The function of IGF-IR in NNK-mediated lung tumorigenesis Academic Article
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The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system Academic Article
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The impact of body mass index in gene expression of reelin pathway mediators in individuals with schizophrenia and mood disorders: A post-mortem study Academic Article
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The integrative role of leptin, oestrogen and the insulin family in obesity‐associated breast cancer: potential effects of exercise Academic Article
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The interplay between the intestinal microbiota and the brain Academic Article
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The lnterleukin-5/Receptor Interaction Activates Lyn and Jak2 Tyrosine Kinases and Propagates Signals via the Ras-Raf-1-MAP Kinase and the Jak-STAT Pathways in Eosinophils Conference Paper
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The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms Academic Article
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The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus Academic Article
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The p53/p21 DNA damage-signaling pathway is defective in most meningioma cells Academic Article
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The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway Academic Article
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The plant signal salicylic acid shuts down expression of the
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The rapid effects of estrogen: a mini-review Academic Article
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The recognition of biomaterials: Pattern recognition of medical polymers and their adsorbed biomolecules Academic Article
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The regulation of cardiac activity by nitric oxide (NO) in the Vietnamese stick insect, Baculum extradentatum Academic Article
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The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise Academic Article
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The role of ICP0-Null HSV-1 and interferon signaling defects in the effective treatment of breast adenocarcinoma Academic Article
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The role of microRNAs in prethrombotic status associated with coronary artery disease Academic Article
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The role of serotonin and its receptors in activation of immune responses and inflammation Academic Article
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The role of sphingosine kinase 2 in alcoholic liver disease Academic Article
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The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression Academic Article
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The sex-limited effects of mutations in the EGFR and TGF-β signaling pathways on shape and size sexual dimorphism and allometry in the Drosophila wing Academic Article
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The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation Academic Article
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The telomerase tale in vascular aging: regulation by estrogens and nitric oxide signaling Academic Article
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The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors Academic Article
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The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis Academic Article
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The tissue polarity gene nemo carries out multiple roles in patterning during Drosophila development Academic Article
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The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells Academic Article
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The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout Academic Article
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Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia Academic Article
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Therapeutic approaches for muscle wasting disorders Academic Article
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Thermosensing Coordinates a Cis-regulatory Module for Transcriptional Activation of the Intracellular Virulence System in Salmonella enterica Serovar Typhimurium Academic Article
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Thrombospondin-1/CD47 signaling modulates transmembrane cation conductance, survival, and deformability of human red blood cells Academic Article
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Thyroid hormone receptor α in breast cancer: prognostic and therapeutic implications Academic Article
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Thyroid hormone regulation of thermal acclimation in ectotherms: Physiological mechanisms and ecoevolutionary implications Academic Article
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Tie2 protects the vasculature against thrombus formation in systemic inflammation Academic Article
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Tissue-Specific Role of Glycogen Synthase Kinase 3β in Glucose Homeostasis and Insulin Action Academic Article
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Tolerance Signaling Molecules Academic Article
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Tolerance Signaling Molecules and Pregnancy: IDO, Galectins, and the Renaissance of Regulatory T Cells Academic Article
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Toll-like Receptor 9, CpG DNA and Innate Immunity Academic Article
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Toll‐Like Receptor (TLR)–3, but Not TLR4, Agonist Protects against Genital Herpes Infection in the Absence of Inflammation Seen with CpG DNA Academic Article
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Transactivation by PPAR/RXR heterodimers in yeast is potentiated by exogenous fatty acid via a pathway requiring intact peroxisomes. Academic Article
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Transcriptome and translational signaling following endurance exercise in trained skeletal muscle: impact of dietary protein Academic Article
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Transcriptomic and proteomic analyses in bone tumor cells: Deciphering parathyroid hormone-related protein regulation of the cell cycle and apoptosis Academic Article
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Transfusion-related immunomodulation due to peripheral blood dendritic cells expressing the CD200 tolerance signaling molecule and alloantigen Academic Article
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Transgenic plants with altered ethylene biosynthesis or perception Academic Article
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Transplantation of human hematopoietic repopulating cells: mechanisms of regeneration and differentiation using human???mouse xenografts Academic Article
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Treatment with apolipoprotein A1 protects mice against doxorubicin-induced cardiotoxicity in a scavenger receptor class B, type I-dependent manner Academic Article
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Treatment-induced cell cycle kinetics dictate tumor response to chemotherapy Academic Article
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Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone Academic Article
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Tryptophan‐derived serotonin‐kynurenine balance in immune activation and intestinal inflammation Academic Article
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Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling Academic Article
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Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity Academic Article
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Type I IFN signaling on dendritic cells is required for NK cell-mediated anti-tumor immunity Academic Article
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Type I interferon signalling is not required for the induction of endotoxin tolerance Academic Article
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Type IV Pilin Proteins: Versatile Molecular Modules Academic Article
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Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages Academic Article
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Tyrosine phosphorylation and cadherin/catenin function Academic Article
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UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways Academic Article
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Uncoupling of Pro- and Anti-Inflammatory Properties of Staphylococcus aureus Academic Article
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Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo Academic Article
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Understanding the Role of DISC1 in Psychiatric Disease and during Normal Development Academic Article
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Up-Regulation of the Complement System in Subcutaneous Adipocytes from Nonobese, Hypertriglyceridemic Subjects Is Associated with Adipocyte Insulin Resistance Academic Article
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Update on bipolar disorder biomarker candidates Academic Article
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Upregulating Nrf2-dependent antioxidant defenses in Pacific oysters Crassostrea gigas: Investigating the Nrf2/Keap1 pathway in bivalves Academic Article
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Upregulation of IL-17A/F from human lung tissue explants with cigarette smoke exposure: implications for COPD Academic Article
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Upregulation of MMP-13 via Runx2 in the stromal cell of Giant Cell Tumor of Bone Academic Article
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Using G-deleted vesicular stomatitis virus to probe the innate anti-viral response Academic Article
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VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents Academic Article
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Vascular Endothelial Tissue Factor Pathway Inhibitor Kinetics in Culture Following Exposure to DX-9065a—A Selective and Direct Factor Xa Inhibitor Academic Article
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Vascular Regenerative Cell Exhaustion in Diabetes: Translational Opportunities to Mitigate Cardiometabolic Risk Academic Article
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Vascular Research at INABIS 98 Academic Article
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Vascular β-adrenoceptor function in hypertension and in ageing Academic Article
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Vasoconstrictor actions of isoprostanes via
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Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle Academic Article
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Vasopressin increases intracellular NO concentration via Ca(2+) signaling in inner medullary collecting duct. Academic Article
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Voices from within: gut microbes and the CNS Academic Article
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W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity Academic Article
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What have we learned from basic science studies on idiopathic pulmonary fibrosis? Academic Article
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Whole-cell and perforated-patch recordings from O2-sensitive rat carotid body cells grown in short- and long-term culture Academic Article
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Wnt3a Activates Dormant c-Kit− Bone Marrow-Derived Cells with Short-Term Multilineage Hematopoietic Reconstitution Capacity Academic Article
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Wnt7a treatment ameliorates muscular dystrophy Academic Article
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cAMP activation of PKA defines an ancient signaling mechanism Academic Article
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miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis Academic Article
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miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells Academic Article
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nMET, A New Target in Recurrent Cancer Academic Article
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p53: The pivot between cell cycle arrest and senescence Academic Article
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p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade Academic Article
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α-Adrenoceptor subtypes of dog saphenous vein: Another unusual property Academic Article
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β-Catenin Causes Renal Dysplasia via Upregulation of Tgfβ2 and Dkk1 Academic Article
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β-Catenin Overexpression in the Metanephric Mesenchyme Leads to Renal Dysplasia Genesis via Cell-Autonomous and Non–Cell-Autonomous Mechanisms Academic Article
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β-Catenin/CBP–Dependent Signaling Regulates TGF-β–Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells Academic Article
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β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens Academic Article
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β-Subunit of the voltage-gated Ca
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β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer Academic Article
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β2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis Academic Article
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β‐adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling Academic Article
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γ-aminobutyric acid nurtures allergic asthma Academic Article