Signal Transduction - McMaster Experts

subject area of

1,25-Dihydroxyvitamin D3Primes Acute Promyelocytic Cells for TPA-Induced Monocytic Differentiation through Both PKC and Tyrosine Phosphorylation Cascades Academic Article
1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells Academic Article
2-[125I]Iodomelatonin Binding in the Brains of Four Salmonids Academic Article
2017 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis Academic Article
4-phenylbutyrate and valproate treatment attenuates the progression of atherosclerosis and stabilizes existing plaques Academic Article
8-isoprostaglandin E2 activates Ca2+-dependent K+ current via cyclic AMP signaling pathway in murine renal artery Academic Article
AJP-Cell Physiology begins a new Theme of Reviews on “Inflammation: From Cellular Mechanisms to Immune Cell Education” Academic Article
Chlamydia pneumoniae Infection of Human Endothelial Cells Induces Proliferation of Smooth Muscle Cells via an Endothelial Cell-Derived Soluble Factor(s) Academic Article
Cynara scolymus affects malignant pleural mesothelioma by promoting apoptosis and restraining invasion Academic Article
Salmonella enterica Serovar Typhimurium Exploits Toll-Like Receptor Signaling during the Host-Pathogen Interaction Academic Article
OX 40L blockade and allergen‐induced airway responses in subjects with mild asthma Academic Article
PhoR autokinase activity is controlled by an intermediate in wall teichoic acid metabolism that is sensed by the intracellular PAS domain during the PhoPR ‐mediated phosphate limitation response of B acillus subtilis Academic Article
cTAZ : a safeguard factor of antiviral response Academic Article
A Budding Relationship: Bacterial Extracellular Vesicles in the Microbiota-Gut-Brain Axis Academic Article
A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease Academic Article
A Dietary Supplement Abolishes Age-Related Cognitive Decline in Transgenic Mice Expressing Elevated Free Radical Processes Academic Article
A Hydroponic Co-cultivation System for Simultaneous and Systematic Analysis of Plant/Microbe Molecular Interactions and Signaling Academic Article
A Mechanism of Extreme Growth and Reliable Signaling in Sexually Selected Ornaments and Weapons Academic Article
A PPARγ mutant serves as a dominant negative inhibitor of PPAR signaling and is localized in the nucleus Academic Article
A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation Academic Article
A STAT3-NFkB/DDIT3/CEBPβ axis modulates ALDH1A3 expression in chemoresistant cell subpopulations Academic Article
A by-product of glutathione production in cancer cells may cause disruption in bone metabolic processesThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease. Academic Article
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation Academic Article
A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials Academic Article
A general mechanism for conditional expression of exaggerated sexually-selected traits Academic Article
A hybrid model to study how late long-term potentiation is affected by faulty molecules in an intraneuronal signaling network regulating transcription factor CREB Academic Article
A large-scale candidate gene association study of age at menarche and age at natural menopause Academic Article
A macrophage-stimulating compound from a screen of microbial natural products Academic Article
A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade Academic Article
A novel function for the competence inducing peptide, XIP, as a cell death effector ofStreptococcus mutans Academic Article
A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells Academic Article
A p56 Ligand Serves as a Coactivator of an Orphan Nuclear Hormone Receptor Academic Article
A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients. Academic Article
A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia Academic Article
A putative Lipid Transfer Protein involved in systemic resistance signaling in Arabidopsis Academic Article
A quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model Academic Article
A randomized, placebo‐controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER) Academic Article
A role for the TGFβ-Par6 polarity pathway in breast cancer progression Academic Article
A role for the scavenger receptor, class B type I in high density lipoprotein dependent activation of cellular signaling pathways Academic Article
A role of SIPL1/SHARPIN in promoting resistance to hormone therapy in breast cancer Academic Article
A set of NF-κB–regulated microRNAs induces acquired TRAIL resistance in Lung cancer Academic Article
A thrombin receptor function for platelet glycoprotein Ib–IX unmasked by cleavage of glycoprotein V Academic Article
A translational view of the genetics of lipodystrophy and ectopic fat deposition. Chapter
ABCF1 Regulates dsDNA-induced Immune Responses in Human Airway Epithelial Cells Academic Article
AHR signaling is induced by infection with coronaviruses Academic Article
AMP-activated protein kinase (AMPK) beyond metabolism Academic Article
AMP-activated protein kinase is required for exercise-induced peroxisome proliferator-activated receptor γ co-activator 1α translocation to subsarcolemmal mitochondria in skeletal muscle Academic Article
AMP-activated protein kinase: the current landscape for drug development Academic Article
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity Academic Article
AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis Academic Article
AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation Academic Article
AMPK-dependent hormonal regulation of whole-body energy metabolism Academic Article
AMPK-independent pathways regulate skeletal muscle fatty acid oxidation Academic Article
AP-2α knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis Academic Article
ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres Academic Article
ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes Academic Article
ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence Academic Article
Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia Academic Article
Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients Academic Article
Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy Academic Article
Abundance of cyclin B1 regulates γ-radiation–induced apoptosis Academic Article
Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression Academic Article
Actions of vasopressin and the Ca(2+)-ATPase inhibitor, thapsigargin, on Ca2+ signaling in hepatocytes. Academic Article
Activated calcineurin ameliorates contraction-induced injury to skeletal muscles ofmdxdystrophic mice Academic Article
Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells Academic Article
Activation of mesangial cell signaling cascades in response to mechanical strain Academic Article
Activation of the Hedgehog Signaling Pathway in the Developing Lens Stimulates EctopicFoxE3Expression and Disruption in Fiber Cell Differentiation Academic Article
Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis Academic Article
Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease Academic Article
Activity Regulates Positive and Negative Neurotrophin-Derived Signals to Determine Axon Competition Academic Article
Activity and expression ofXenopus laevis matrix metalloproteinases: Identification of a novel role for the hormone prolactin in regulating collagenolysis in both amphibians and mammals Academic Article
Addressing taxane resistance in metastatic castration-resistant prostate cancer: a focus on chaperone proteins Academic Article
Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway Academic Article
Adiponectin inhibits oxidative stress in human prostate carcinoma cells Academic Article
Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy Academic Article
Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats Academic Article
Adipose tissue as an endocrine organ Academic Article
Administration of dexamethasone protects mice against ischemia/reperfusion induced renal injury by suppressing PI3K/AKT signaling. Academic Article
Age-Related Resistance in Arabidopsis Is a Developmentally Regulated Defense Response to Pseudomonas syringae Academic Article
Airway smooth muscle in asthma: Phenotype plasticity and function Conference Paper
Akt Mediates Mechanical Strain-Induced Collagen Production by Mesangial Cells Academic Article
Alcohol Ingestion Impairs Maximal Post-Exercise Rates of Myofibrillar Protein Synthesis following a Single Bout of Concurrent Training Academic Article
Allergen-induced increase in bone marrow progenitors in airway hyperresponsive dogs: regulation by a serum hemopoietic factor. Academic Article
Allosteric pluripotency: challenges and opportunities Academic Article
Alterations in Skeletal Muscle Cell Homeostasis in a Mouse Model of Cigarette Smoke Exposure Academic Article
Alterations of immune response of non-small cell lung cancer with Azacytidine Academic Article
Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling Academic Article
Amplification of MUC1 in prostate cancer metastasis and CRPC development Academic Article
Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis Academic Article
An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity Academic Article
An emerging role for Wnt and GSK3 signaling pathways in schizophrenia Academic Article
An inducible model of human amylin overexpression reveals diverse transcriptional changes Academic Article
Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture Academic Article
Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise Academic Article
Analysis of the Human Fetal Liver Hematopoietic Microenvironment Academic Article
Androgen Induces Adaptation to Oxidative Stress in Prostate Cancer: Implications for Treatment with Radiation Therapy Academic Article
Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression Academic Article
Angiogenesis in the Placenta: The Role of Reactive Oxygen Species Signaling Academic Article
Angiotensin II mobilizes intracellular calcium and activates pannexin-1 channels in rat carotid body type II cells via AT₁receptors Academic Article
Anormalidades neuropatológicas e neuroquímicas no transtorno afetivo bipolar Academic Article
Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions Academic Article
Anti-Inflammatory Effects of Tanshinone IIA on Atherosclerostic Vessels of Ovariectomized ApoE-/- Mice are Mediated by Estrogen Receptor Activation and Through the ERK Signaling Pathway Academic Article
Anti-pneumococcal deficits of monocyte-derived macrophages from the advanced-age, frail elderly and related impairments in PI3K-AKT signaling Academic Article
Antialarmins for treatment of asthma Academic Article
Antibodies to rat soluble IL-6 receptor stimulate B9 hybridoma cell proliferation Academic Article
Antifibrotic Role of αB-Crystallin Inhibition in Pleural and Subpleural Fibrosis Academic Article
Antiplatelet Effect of Active Components Derived from Chinese Herbal Medicine Academic Article
Apoptosis induction by eIF5A1 involves activation of the intrinsic mitochondrial pathway Academic Article
Apoptosis is initiated in human keratinocytes exposed to signalling factors from microbeam irradiated cells Academic Article
Apoptosis is signalled early by low doses of ionising radiation in a radiation-induced bystander effect Academic Article
Are SIRT1 activators another indirect method to increase AMPK for beneficial effects on aging and the metabolic syndrome? Academic Article
Are endothelium-derived hyperpolarizing and contracting factors isoprostanes? Academic Article
Argos and Spitz group genes function to regulate midline glial cell number in Drosophila embryos Academic Article
Aryl hydrocarbon receptor control of a disease tolerance defence pathway Academic Article
Association of Interleukin-6 Signalling with the Muscle Stem Cell Response Following Muscle-Lengthening Contractions in Humans Academic Article
Association of Phosphorylated Epidermal Growth Factor Receptor with Survival in Patients with Locally Advanced Non-small Cell Lung Cancer Treated with Radiotherapy Academic Article
Asthma therapy: how far have we come, why did we fail and where should we go next? Academic Article
Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis Academic Article
Atorvastatin Delays Murine Platelet Activation In Vivo Even in the Absence of Endothelial NO Synthase Academic Article
Attenuation ofClostridium difficiletoxin-induced damage to epithelial barrier by ecto-5′-nucleotidase (CD73) and adenosine receptor signaling Academic Article
Axon repulsion from the midline of the Drosophila CNS requires slit function Academic Article
B Cell Maintenance of Subcapsular Sinus Macrophages Protects against a Fatal Viral Infection Independent of Adaptive Immunity Academic Article
B7RP-1 Is Not Required for the Generation of Th2 Responses in a Model of Allergic Airway Inflammation but Is Essential for the Induction of Inhalation Tolerance Academic Article
BDNF/TrkB Content and Interaction with Gastrin-Releasing Peptide Receptor Blockade in Colorectal Cancer Academic Article
BH3-only proteins: Orchestrators of apoptosis Academic Article
BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer Academic Article
Bacterial Peptidoglycan Stimulates Adipocyte Lipolysis via NOD1 Academic Article
Bacterial lipids Academic Article
Basic and Translational Research in Intracerebral Hemorrhage Academic Article
Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line Academic Article
Beneficial effects of resveratrol on respiratory chain defects in patients' fibroblasts involve estrogen receptor and estrogen-related receptor alpha signaling Academic Article
Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and prostaglandin E2 (PGE2) output Academic Article
Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways Academic Article
Binding of Anti-GRP78 Autoantibodies to Cell Surface GRP78 Increases Tissue Factor Procoagulant Activity via the Release of Calcium from Endoplasmic Reticulum Stores Academic Article
Bio-acoustic signaling; exploring the potential of sound as a mediator of low-dose radiation and stress responses in the environment Academic Article
Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region Academic Article
Bisphosphonates Target B Cells to Enhance Humoral Immune Responses Academic Article
Bone Morphogenetic Proteins Regulate the Developmental Program of Human Hematopoietic Stem Cells Academic Article
Bone cancer-induced pain is associated with glutamate signalling in peripheral sensory neurons Academic Article
Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract Academic Article
Bystander effects of ionizing radiation can be modulated by signaling amines Academic Article
Bystander signal production and response are independent processes which are cell line dependent Academic Article
Bystander-induced differentiation: A major response to targeted irradiation of a urothelial explant model Academic Article
C. elegans electrotaxis behavior is modulated by heat shock response and unfolded protein response signaling pathways Academic Article
CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection Academic Article
CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence Academic Article
CD200-dependent and nonCD200-dependant pathways of NK cell suppression by human IVIG Academic Article
CD23-mediated transport of IgE/immune complexes across human intestinal epithelium: role of p38 MAPK Academic Article
CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis Academic Article
CDP-diacylglycerol, a critical intermediate in lipid metabolism Academic Article
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK Academic Article
CO₂/pH Chemosensory Signaling in Co-Cultures of Rat Carotid Body Receptors and Petrosal Neurons: Role of ATP and ACh Academic Article
COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux Academic Article
CXCL12/CXCR4 Signaling Enhances Human PSC-Derived Hematopoietic Progenitor Function and Overcomes Early In Vivo Transplantation Failure Academic Article
CXCL9 Contributes to Antimicrobial Protection of the Gut during Citrobacter rodentium Infection Independent of Chemokine-Receptor Signaling Academic Article
CXCR3 Signaling Is Required for Restricted Homing of Parenteral Tuberculosis Vaccine–Induced T Cells to Both the Lung Parenchyma and Airway Academic Article
CYFIP/Sra-1 Controls Neuronal Connectivity in Drosophila and Links the Rac1 GTPase Pathway to the Fragile X Protein Academic Article
Ca²⁺/calmodulin-dependent protein kinase IIβ and IIδ mediate TGFβ-induced transduction of fibronectin and collagen in human pulmonary fibroblasts Academic Article
Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β Academic Article
Caenorhabditis elegans SMA-10/LRIG Is a Conserved Transmembrane Protein that Enhances Bone Morphogenetic Protein Signaling Academic Article
Calcium Regulation and Contractile Dysfunction of Smooth Muscle Academic Article
Caloxin: a novel plasma membrane Ca²⁺pump inhibitor Academic Article
Canadian Association of Neurosciences Review: Polyglutamine Expansion Neurodegenerative Diseases Academic Article
Cancer phenomics: RET and PTEN as illustrative models Academic Article
Canonical WNT/β-catenin signaling is required for ureteric branching Academic Article
Captopril treatment induces hyperplasia but inhibits myonuclear accretion following severe myotrauma in murine skeletal muscle Academic Article
Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans Academic Article
Carotid Body Adaptation to Hypoxia: Cellular and Molecular Mechanisms in vitro Academic Article
Caveolin-1 in the Pathogenesis of Diabetic Nephropathy: Potential Therapeutic Target? Academic Article
Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy Academic Article
Cell-free Tumor Microparticle Vaccines Stimulate Dendritic Cells via cGAS/STING Signaling Academic Article
Cells Exposed to Sublethal Oxidative Stress Selectively Attract Monocytes/Macrophages via Scavenger Receptors and MyD88-Mediated Signaling Academic Article
Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness Academic Article
Cellular metabolic homeostasis during large-scale change in ATP turnover rates in muscles. Academic Article
Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function Academic Article
Changes in HIF-1α protein, pyruvate dehydrogenase phosphorylation, and activity with exercise in acute and chronic hypoxia Academic Article
Changes in expression of the CD200 tolerance-signaling molecule and its receptor (CD200R) by villus trophoblasts during first trimester missed abortion and in chronic histiocytic intervillositis Academic Article
Chapter 7 Evidence that the Merkel cell is not the transducer in the mechanosensory Merkel cell – neurite complex Academic Article
Characterization of Chemokine Receptors Expressed in Primitive Blood Cells During Human Hematopoietic Ontogeny Academic Article
Characterization of Radioprotective, Radiomitigative and Bystander Signaling Modulating Effects of Endogenous Metabolites – Phenylacetate, Ursodeoxycholate and Tauroursodeoxycholate – on HCT116 Human Colon Carcinoma Cell Line Academic Article
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance Academic Article
Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells Academic Article
Characterizing the Role of Glycogen Synthase Kinase-3α/β in Macrophage Polarization and the Regulation of Pro-Atherogenic Pathways in Cultured Ldlr-/- Macrophages Academic Article
Chemical Interactions between Organisms in Microbial Communities Academic Article
Chemosensing and signal transduction in bacteria Academic Article
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signaling. Academic Article
Chlamydiae Host Cell Interactions Revealed Using DNA Microarrays Academic Article
Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle Academic Article
Chronic modulation of AMP-Kinase, Akt and mTOR pathways by ionizing radiation in human lung cancer xenografts Academic Article
Cigarette Smoke Exposure Triggers the Autophagic Cascade via Activation of the AMPK Pathway in Mice1 Academic Article
Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis inSmad3knockout mice Academic Article
Cigarette smoke upregulates pulmonary vascular matrix metalloproteinases via TNF-α signaling Academic Article
Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice Academic Article
Ciliary Neurotrophic Factor Suppresses Hypothalamic AMP-Kinase Signaling in Leptin-Resistant Obese Mice Academic Article
Circulating Peroxiredoxin-1 is a novel damage-associated molecular pattern and aggravates acute liver injury via promoting inflammation Academic Article
Class A Scavenger Receptor–Mediated Double-Stranded RNA Internalization Is Independent of Innate Antiviral Signaling and Does Not Require Phosphatidylinositol 3-Kinase Activity Academic Article
Classification, hepatotoxic mechanisms, and targets of the risk ingredients in traditional Chinese medicine-induced liver injury Academic Article
Clinical Implications of Targeting the JAK-STAT Pathway in Psoriatic Disease: Emphasis on the TYK2 Pathway Academic Article
Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia Academic Article
Collagen I induction by high glucose levels is mediated by epidermal growth factor receptor and phosphoinositide 3-kinase/Akt signalling in mesangial cells Academic Article
Combinatorial therapeutic activation with heparin and AICAR stimulates additive effects on utrophin A expression in dystrophic muscles Academic Article
Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development Academic Article
Communication in bacteria: an ecological and evolutionary perspective Academic Article
Communication of Radiation-Induced Signals in Vivo between DNA Repair Deficient and Proficient Medaka (Oryzias latipes) Academic Article
Communication of ionising radiation signals – a tale of two fish Academic Article
Comparative Proteomics Analysis of Arabidopsis Phloem Exudates Collected During the Induction of Systemic Acquired Resistance Academic Article
Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress Academic Article
Competence for collagenase gene expression by tissue fibroblasts requires activation of an interleukin 1 alpha autocrine loop. Academic Article
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma Academic Article
Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells Academic Article
Conditioned medium from hypoxia-treated adipocytes renders muscle cells insulin resistant Academic Article
Conserved Features and Evolutionary Shifts of the EDA Signaling Pathway Involved in Vertebrate Skin Appendage Development Academic Article
Conserved mechanism of Wnt signaling function in the specification of vulval precursor fates in C. elegans and C. briggsae Academic Article
Contactin 1: An Important and Emerging Oncogenic Protein Promoting Cancer Progression and Metastasis Academic Article
Contraction-related stimuli regulate GLUT4 traffic in C₂C₁₂-GLUT4mycskeletal muscle cells Academic Article
Control of Pathogenic CD4 T Cells and Lethal Immunopathology by Signaling Immunoadaptor DAP12 during Influenza Infection Academic Article
Controlling skeletal muscle CPT-I malonyl-CoA sensitivity: the importance of AMPK-independent regulation of intermediate filaments during exercise Academic Article
Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma Academic Article
Cooperation in signal transduction of extracellular guanosine 5′ triphosphate and nerve growth factor in neuronal differentiation of PC12 cells Academic Article
Coordinated Regulation of Two Independent Cell-Cell Signaling Systems and Swarmer Differentiation in Salmonella enterica Serovar Typhimurium Academic Article
Coordination of metabolic plasticity in skeletal muscle Academic Article
Corneal development: Role of the periocular mesenchyme and bi-directional signaling Academic Article
Critical Illness-Related Corticosteroid Insufficiency (CIRCI) Academic Article
Critical Role of Natural Killer Cells in Lung Immunopathology During Influenza Infection in Mice Academic Article
Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM) Academic Article
Cross-talk between Orphan Nuclear Hormone Receptor RZRα and Peroxisome Proliferator-activated Receptor α in Regulation of the Peroxisomal Hydratase-Dehydrogenase Gene Academic Article
Crosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis Academic Article
Crosstalk between the Unfolded Protein Response and NF-κB-Mediated Inflammation in the Progression of Chronic Kidney Disease Academic Article
Crosstalk between the thyroid hormone and peroxisome proliferator-activated receptors in regulating peroxisome proliferator-responsive genes Academic Article
Cytokine Regulation of AMPK signalling Academic Article
Cytokine control of acute phase protein expression. Academic Article
Cytokine-Induced Hepatic Apoptosis Is Dependent on FGL2/Fibroleukin: The Role of Sp1/Sp3 and STAT1/PU.1 Composite cis Elements Academic Article
Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130) Academic Article
DNA Repair Signaling of Huntingtin: The Next Link Between Late-Onset Neurodegenerative Disease and Oxidative DNA Damage Academic Article
Dancing in and out of the nucleus: p120ctn and the transcription factor Kaiso Academic Article
Danger, diversity and priming in innate antiviral immunity Academic Article
Deconstructing human embryonic stem cell cultures: niche regulation of self-renewal and pluripotency Academic Article
Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis Academic Article
Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Is the Result of Altered Notch Signaling Academic Article
Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid Academic Article
Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice Academic Article
Deletion ofMAP2K2/MEK2: a novel mechanism for a RASopathy? Academic Article
Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis Academic Article
Differences between platelet phosphoinositide metabolism stimulated by thrombin or SFLLRN are not accounted for by interaction of thrombin with glycoprotein Ib Academic Article
Differences in Functional Consequences and Signal Transduction Induced by IL-3, IL-5, and Nerve Growth Factor in Human Basophils Academic Article
Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle Academic Article
Differential regulation of striatal G protein levels following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration in C57 BL/6 mice Academic Article
Dimerization Is Required for the Activity of the Protein Histidine Kinase CheA That Mediates Signal Transduction in Bacterial Chemotaxis Academic Article
Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance Academic Article
Diminished contraction-induced intracellular signaling towards mitochondrial biogenesis in aged skeletal muscle Academic Article
Direct Microbicidal Activity of Cytotoxic T-Lymphocytes Academic Article
Disassembly of the actin network inhibits insulin-dependent stimulation of glucose transport and prevents recruitment of glucose transporters to the plasma membrane. Academic Article
Disordered Regions Flanking Ordered Domains Modulate Signaling Transduction Academic Article
Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling Academic Article
Disruption of β-catenin/CBP signaling inhibits human airway epithelial–mesenchymal transition and repair Academic Article
Disruptive physiology: olfaction and the microbiome-gut-brain axis Academic Article
Dissociation of AMPK activity and ACCβ phosphorylation in human muscle during prolonged exercise Academic Article
Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression Academic Article
Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice Academic Article
Distinguishing Between Mouse and Human Pluripotent Stem Cell Regulation: The Best Laid Plans of Mice and Men Academic Article
Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development Academic Article
Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation Academic Article
Druggable targets in pediatric neurocutaneous melanocytosis: Molecular and drug sensitivity studies in xenograft and ex vivo tumor cell culture to identify agents for therapy Academic Article
Dual Pathway for Promotion of Stem Cell Neural Differentiation Mediated by Gold Nanocomposites Academic Article
Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract Academic Article
Dual roles of parathyroid hormone related protein in TGF-β1 signaling and fibronectin up-regulation in mesangial cells Academic Article
Dual-action peptides: a new strategy in the treatment of diabetes-associated neuropathy Academic Article
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human Academic Article
Dysfunctional Nrf2–Keap1 redox signaling in skeletal muscle of the sedentary old Academic Article
Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK Academic Article
EGF Decreases the Abundance of MicroRNAs That Restrain Oncogenic Transcription Factors Academic Article
ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response. Academic Article
Early Intraplatelet Signaling Enhances the Release of Human Platelet PAR-1 and -4 Amino-Terminal Peptides in Response to Thrombin Academic Article
Early cardiac development: A Wnt beat away Academic Article
Eccentric Exercise Activates Novel Transcriptional Regulation of Hypertrophic Signaling Pathways Not Affected by Hormone Changes Academic Article
Editorial: You give me fever: transcriptional responses to LPS Academic Article
Effect of dose rate on the radiation-induced bystander response Academic Article
Effect of gamma radiation on the production of bystander signals from three earthworm species irradiated in vivo Academic Article
Effects of Activators of Different Intracellular Signaling Pathways on Steroid Production by Goldfish Vitellogenic Ovarian Follicles Academic Article
Effects of Chronic Treatment of Haloperidol and Clozapine on Levels of G-Protein Subunits in Rat Striatum Academic Article
Effects of Dystrophin Isoforms on Signal Transduction through Neural Retina: Genotype–Phenotype Analysis of Duchenne Muscular Dystrophy Mouse Mutants Academic Article
Effects of Maternal Dexamethasone Treatment Early in Pregnancy on Glucocorticoid Receptors in the Ovine Placenta Academic Article
Effects of MeCh, thapsigargin, and La3+ on plasmalemmal and intracellular Ca2+ transport in lacrimal acinar cells Academic Article
Effects of Reactive Oxygen and Nitrogen Species on TrkA Expression and Signalling: Implications for proNGF in Aging and Alzheimer’s Disease Academic Article
Effects of biomaterial-induced inflammation on fibrosis and rejection Academic Article
Elevated SOCS3 and altered IL-6 signaling is associated with age-related human muscle stem cell dysfunction Academic Article
Elevated basal transcription can underlie timothy channel association with autism related disorders Academic Article
Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule Academic Article
Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis Academic Article
Endothelin-1, but not angiotensin II, induces afferent arteriolar myosin diphosphorylation as a potential contributor to prolonged vasoconstriction Academic Article
Endurance training partially reverses dietary-induced leptin resistance in rodent skeletal muscle Academic Article
Energy-stress-mediated AMPK activation inhibits ferroptosis Academic Article
Enhanced Amino Acid Sensitivity of Myofibrillar Protein Synthesis Persists for up to 24 h after Resistance Exercise in Young Men1–3 Academic Article
Enhanced BDNF signalling following chronic hypoxia potentiates catecholamine release from cultured rat adrenal chromaffin cells Academic Article
Enhanced Lipid Oxidation and Maintenance of Muscle Insulin Sensitivity Despite Glucose Intolerance in a Diet-Induced Obesity Mouse Model Academic Article
Enhanced TH17 Responses in Patients with IL10 Receptor Deficiency and Infantile-onset IBD Academic Article
Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662 Academic Article
Enhanced adenosine A_2breceptor signaling facilitates stimulus-induced catecholamine secretion in chronically hypoxic carotid body type I cells Academic Article
Epidermal Growth Factor Receptor and Transforming Growth Factor-β Signaling Contributes to Variation for Wing Shape in Drosophila melanogaster Academic Article
Epidermal Growth Factor Receptor: Pathway, Therapies, and Pipeline Academic Article
Epidermal growth factor receptor deficiency: Expanding the phenotype beyond infancy Academic Article
Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1 Academic Article
Epigenetic Regulation of SOX9 by the NF-κB Signaling Pathway in Pancreatic Cancer Stem Cells Academic Article
Epigenetic induction of melatonin MT 1 receptors by valproate: Neurotherapeutic implications Academic Article
Epigenetic mechanisms of melatonin action in human SH-SY5Y neuroblastoma cells Academic Article
Epigenetic silencing of miR-145-5p contributes to brain metastasis Academic Article
ErbB Receptor Signaling and Therapeutic Resistance to Aromatase Inhibitors Conference Paper
Estrogen Receptor β Is a Novel Target in Acute Myeloid Leukemia Academic Article
Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors Academic Article
Estrogen-Dependent Dynamic Profile of eNOS-DNA Associations in Prostate Cancer Academic Article
Ethylenecarbodiimide-Fixed Donor Splenocyte Infusions Differentially Target Direct and Indirect Pathways of Allorecognition for Induction of Transplant Tolerance Academic Article
Evasive Maneuvers by Secreted Bacterial Proteins to Avoid Innate Immune Responses Academic Article
Evidence That the Epidermal Growth Factor Receptor on Host Cells Confers Reovirus Infection Efficiency Academic Article
Evidence for P2-purinoceptors contribution in H2O2-induced contraction of rat aorta in the absence of endothelium Academic Article
Evidence for a protective response by the gill proteome of rainbow trout exposed to X-ray induced bystander signals Academic Article
Evidence for neuronal expression of functional Fc (ε and γ) receptors Academic Article
Evidence for protein kinase involvement in the 5‐HT–[Ca²⁺]_i–pannexin‐1 signalling pathway in type II glial cells of the rat carotid body Academic Article
Evidence for the role of AMPK in regulating PGC‐1 alpha expression and mitochondrial proteins in mouse epididymal adipose tissue Academic Article
Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differences Academic Article
Exercise-induced Protein Arginine Methyltransferase Expression in Skeletal Muscle Academic Article
Exercise‐stimulated interleukin‐15 is controlled by AMPK and regulates skin metabolism and aging Academic Article
Expanding Role of Dopaminergic Inhibition in Hypercapnic Responses of Cultured Rat Carotid Body Cells: Involvement of Type II Glial Cells Academic Article
Expanding role of ATP as a versatile messenger at carotid and aortic body chemoreceptors Academic Article
Exploration of trade-offs between steady-state and dynamic properties in signaling cycles Academic Article
Exploring Pluripotency with Chemical Genetics Academic Article
Expression of Multiple P2X Receptors by Glossopharyngeal Neurons Projecting to Rat Carotid Body O₂-Chemoreceptors: Role in Nitric Oxide-Mediated Efferent Inhibition Academic Article
Expression of P2X2 and P2X3 receptor subunits in rat carotid body afferent neurones: role in chemosensory signalling Academic Article
Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3 Academic Article
Expression of survivin and p16INK4a/Cdk6/pRB proteins and induction of apoptosis in response to radiation and cisplatin in meningioma cells Academic Article
Expression of the β4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells Academic Article
Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors Academic Article
Extracellular DNA and histones: double‐edged swords in immunothrombosis Academic Article
Extracellular matrix regulates human airway smooth muscle cell migration Academic Article
Extrinsic signals determine myeloid-erythroid lineage switch in MN1 leukemia Academic Article
FGF-Regulated Etv Genes Are Essential for Repressing Shh Expression in Mouse Limb Buds Academic Article
Fc Gamma Receptor Signaling in Mast Cells Links Microbial Stimulation to Mucosal Immune Inflammation in the Intestine Academic Article
Features of the Phosphatidylinositol Cycle and its Role in Signal Transduction Academic Article
Fetal and Neonatal Exposure to Nicotine Disrupts Postnatal Lung Development in Rats: Role of VEGF and Its Receptors Academic Article
Fetal growth interacts with multilocus genetic score reflecting dopamine signaling capacity to predict spontaneous sugar intake in children Academic Article
Filamin A Regulates Monocyte Migration Through Rho Small GTPases During Osteoclastogenesis Academic Article
FimH Adhesin of Type 1 Fimbriae Is a Potent Inducer of Innate Antimicrobial Responses Which Requires TLR4 and Type 1 Interferon Signalling Academic Article
Fish oil supplementation suppresses resistance exercise and feeding-induced increases in anabolic signaling without affecting myofibrillar protein synthesis in young men Academic Article
Fisiopatologia do transtorno afetivo bipolar: o que mudou nos últimos 10 anos? Academic Article
Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues Academic Article
FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells Academic Article
Functional Redundancy of GSK-3α and GSK-3β in Wnt/β-Catenin Signaling Shown by Using an Allelic Series of Embryonic Stem Cell Lines Academic Article
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells Academic Article
Functional impact of global rare copy number variation in autism spectrum disorders Academic Article
Functional linkage as a direction for studies in oxidative stress: α-adrenergic receptorsThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease. Academic Article
Fundamentals of Neurogastroenterology: Basic Science Academic Article
Future Directions in the Treatment of Neuropathic Pain: A Review on Various Therapeutic Targets Academic Article
G Protein-coupled Receptor Kinase-mediated Desensitization of Metabotropic Glutamate Receptor 1A Protects against Cell Death Academic Article
G-Protein–Coupled Receptors as Signaling Targets for Antiplatelet Therapy Academic Article
GLP-1R Agonists Modulate Enteric Immune Responses Through the Intestinal Intraepithelial Lymphocyte GLP-1R Academic Article
GSK-3 is a master regulator of neural progenitor homeostasis Academic Article
GSK-3: tricks of the trade for a multi-tasking kinase Academic Article
GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in mice Academic Article
GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia Academic Article
GTP and guanosine synergistically enhance NGF-induced neurite outgrowth from PC12 cells Academic Article
Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling Academic Article
Genetic analysis of vein function in the Drosophila embryonic nervous system Academic Article
Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model Academic Article
Genome‐wideDNAmethylation changes with age in disease‐free human skeletal muscle Academic Article
Genomic Minimalism in the Early Diverging Intestinal Parasite Giardia lamblia Academic Article
Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma Academic Article
Germline variation in the insulin-like growth factor pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma Academic Article
Gli3-mediated hedgehog inhibition in human pluripotent stem cells initiates and augments developmental programming of adult hematopoiesis Academic Article
Glucocortiosteroid subsensitivity and asthma severity Academic Article
Glucose‐regulated protein ( GRP78 ) is an important cell surface receptor for viral invasion, cancers, and neurological disorders Academic Article
Glycogen Synthase Kinase 3α Deficiency Attenuates Atherosclerosis and Hepatic Steatosis in High Fat Diet–Fed Low Density Lipoprotein Receptor–Deficient Mice Academic Article
Glycogen Synthase Kinase-3 - An Overview of An Over-Achieving Protein Kinase Academic Article
Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells Academic Article
Glycogen synthase kinase-3 in insulin and Wnt signalling: a double-edged sword? Academic Article
Glycosyltransferases and Glycosaminoglycans in Bleomycin and Transforming Growth Factor-β1–Induced Pulmonary Fibrosis Academic Article
Glypican LON-2 Is a Conserved Negative Regulator of BMP-like Signaling in Caenorhabditis elegans Academic Article
Green tea catechins evoke a phasic contraction in rat aorta via H2O2-mediated multiple-signalling pathways Academic Article
Guanosine 5´-O-(3-Thiotriphosphate) and Cations Regulate Melatonin Receptors, and Melatonin Inhibits Cyclic AMP Production in the Spinal Cord Academic Article
Guanosine Inhibits CD40 Receptor Expression and Function Induced by Cytokines and β Amyloid in Mouse Microglia Cells Academic Article
Guanosine Protects Glial Cells Against 6-Hydroxydopamine Toxicity Academic Article
Guanosine promotes proliferation of neural stem cells through cAMP-CREB pathway. Academic Article
Guidance signalling regulates leading edge behaviour during collective cell migration of cardiac cells in Drosophila Academic Article
Gut Microbiota and Brain Function: An Evolving Field in Neuroscience: Table 1. Academic Article
Gut commensal microvesicles reproduce parent bacterial signals to host immune and enteric nervous systems Academic Article
H9724, a monoclonal antibody to Borrelia burgdorferi's flagellin, binds to heat shock protein 60 (HSP60) within live neuroblastoma cells: a potential role for HSP60 in peptide hormone signaling and in an autoimmune pathogenesis of the neuropathy of Lyme disease. Academic Article
HB-EGF release mediates glucose-induced activation of the epidermal growth factor receptor in mesangial cells Academic Article
HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants Academic Article
HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner Academic Article
HIV-1 gp120 Induces TLR2- and TLR4-Mediated Innate Immune Activation in Human Female Genital Epithelium Academic Article
HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells Academic Article
HSP90 modulates actin dynamics: Inhibition of HSP90 leads to decreased cell motility and impairs invasion Academic Article
HUMAN PLATELET THROMBIN RECEPTORS Academic Article
Haemopoietic processes in allergic disease: eosinophil/basophil development Academic Article
Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling Academic Article
Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration Academic Article
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia Academic Article
Hematopoietic stem cell biology: too much of a Wnt thing Academic Article
Heparin Inhibits Melatonin Binding and Signal Transduction in Chick Brain Academic Article
Heparin Synergistically Enhances Interleukin-11 Signaling through Up-regulation of the MAPK Pathway Academic Article
Hepatic Glucose Intolerance Precedes Hepatic Steatosis in the Male Aromatase Knockout (ArKO) Mouse Academic Article
Herpes Simplex Virus 1 Tegument Protein US11 Downmodulates the RLR Signaling Pathway via Direct Interaction with RIG-I and MDA-5 Academic Article
Herpes Simplex Virus Triggers and Then Disarms a Host Antiviral Response Academic Article
Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells Academic Article
High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells Academic Article
High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus Academic Article
High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells Academic Article
High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2 Academic Article
Histamine activates Cl- and K+ currents in guinea-pig tracheal myocytes: convergence with muscarinic signalling pathway. Academic Article
Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy Academic Article
History of bystander effects research 1905-present; what is in a name? Academic Article
Host Defence Peptide LL-37 Induces IL-6 Expression in Human Bronchial Epithelial Cells by Activation of the NF-κB Signaling Pathway Academic Article
Host Defense Peptide LL-37, in Synergy with Inflammatory Mediator IL-1β, Augments Immune Responses by Multiple Pathways Academic Article
How Linear Tension Converts to Curvature: Geometric Control of Bone Tissue Growth Academic Article
How is Mitochondrial Biogenesis Affected in Mitochondrial Disease? Academic Article
Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia Academic Article
Human Milk Oligosaccharides Protect against Necrotizing Enterocolitis by Activating Intestinal Cell Differentiation Academic Article
Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells Academic Article
Hydrogen peroxide is an endothelium-dependent contracting factor in rat renal artery Academic Article
Hydrogen sulfide in the pathogenesis of atherosclerosis and its therapeutic potential Academic Article
Hydrogen sulfide is a regulator of mammary gland development in prepubescent female mice Academic Article
Hydroxychloroquine attenuates cigarette smoke induced autophagic signaling in the mouse ovary Academic Article
Hyperinsulinemia-induced vascular smooth muscle cell (VSMC) migration and proliferation is mediated by converging mechanisms of mitochondrial dysfunction and oxidative stress Academic Article
Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response Academic Article
Hypoxia-Driven Immune Escape in the Tumor Microenvironment Academic Article
Hypoxia-induced autophagy, epithelial to mesenchymal transition, and invasion in the pathophysiology of endometriosis: a perspective Academic Article
Hypoxia-inducible factor-1α mediates the expression of mature β cell-disallowed genes in hypoxia-induced β cell dedifferentiation Academic Article
IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity Academic Article
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro Academic Article
II. The intestine as a sensory organ: neural, endocrine, and immune responses Academic Article
IL-15 Can Signal via IL-15Rα, JNK, and NF-κB To Drive RANTES Production by Myeloid Cells Academic Article
IL-15 and Type I Interferon Are Required for Activation of Tumoricidal NK Cells by Virus-Infected Dendritic Cells Academic Article
IL-15 has innate anti-tumor activity independent of NK and CD8 T cells Academic Article
IL-17 Receptor Signaling Inhibits C/EBPβ by Sequential Phosphorylation of the Regulatory 2 Domain Academic Article
IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization Academic Article
IL-4 and IL-13 Differentially Regulate TLR-Induced Eosinophil-Basophil Differentiation of Cord Blood CD34+ Progenitor Cells Academic Article
IL-6 Induced STAT3 Signalling Is Associated with the Proliferation of Human Muscle Satellite Cells Following Acute Muscle Damage Academic Article
IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages Academic Article
IL‐25 promotes cisplatin resistance of lung cancer cells by activating NF‐κB signaling pathway to increase of major vault protein Academic Article
Identification and Characterization of New Inhibitors of Fungal Homoserine Kinase Academic Article
Identification of COUP-TFII as a peroxisome proliferator response element binding factor using genetic selection in yeast: COUP-TFII activates transcription in yeast but anatagonizes PPAR signaling in mammalian cells Academic Article
Identification of Dp71 Isoforms in the Platelet Membrane Cytoskeleton Academic Article
Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells Academic Article
Identification of Synthetic Peptides that Inhibit Lipopolysaccharide (LPS) Binding to Myeloid Differentiation Protein-2 (MD-2) Academic Article
Identification of a Novel Pathway Essential for the Immediate-Early, Interferon-Independent Antiviral Response to Enveloped Virions Academic Article
Identification of early breast cancer patient cohorts who may benefit from lapatinib therapy Academic Article
Identification of periplakin as a major regulator of lung injury and repair in mice Academic Article
IgA potentiates NETosis in response to viral infection Academic Article
Imaging Correlates of Molecular Signatures in Oligodendrogliomas Academic Article
Immune Inhibitory Ligand CD200 Induction by TLRs and NLRs Limits Macrophage Activation to Protect the Host from Meningococcal Septicemia Academic Article
Immunological Events Underlying the Induction of T Cell Non-Responsiveness Academic Article
Immunometabolism of AMPK in insulin resistance and atherosclerosis Academic Article
Immunometabolism of obesity and diabetes: microbiota link compartmentalized immunity in the gut to metabolic tissue inflammation Academic Article
Impact of the menstrual cycle on peripheral vascular function in premenopausal women: systematic review and meta-analysis Academic Article
Impaired Growth and Force Production in Skeletal Muscles of Young Partially Pancreatectomized Rats: A Model of Adolescent Type 1 Diabetic Myopathy? Academic Article
Impaired c-src activation and motility defects in PEA3-null fibroblasts Academic Article
Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis Academic Article
In Vitro Selection of Structure‐Switching Signaling Aptamers Academic Article
Increased FGF8 signaling promotes chondrogenic rather than osteogenic development in the embryonic skull Academic Article
Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes Academic Article
Increased Placental Apoptosis in Maternal Food Restricted Gestations: Role of the Fas Pathway Academic Article
Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling Academic Article
Induction of interleukin-10 and suppressor of cytokine signalling-3 gene expression following peptide immunotherapy Academic Article
Inflammasomes in the lung Academic Article
Inflammation in Obesity is a Common Link Between Defects in Fatty Acid Metabolism and Insulin Resistance Academic Article
Inflammation promotes adipocyte lipolysis via IRE1 kinase Academic Article
Inflammation, depression and cardiovascular disease in women: the role of the immune system across critical reproductive events Academic Article
Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection Academic Article
Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation Academic Article
Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Academic Article
Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin Academic Article
Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice Academic Article
Inhibition of TGF? signaling potentiates the FGF-2-induced stimulation of cardiomyocyte DNA synthesis Academic Article
Inhibition of endogenous MTF-1 signaling in zebrafish embryos identifies novel roles for MTF-1 in development Academic Article
Inhibition of sporulation, glycopeptide antibiotic production and resistance in Streptomyces toyocaensis NRRL 15009 by protein kinase inhibitors Academic Article
Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin Academic Article
Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain Academic Article
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions Academic Article
Innate Immune Cytokines, Fibroblast Phenotypes, and Regulation of Extracellular Matrix in Lung Academic Article
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism Academic Article
Innate and adaptive immunity against herpes simplex virus type 2 in the genital mucosa Academic Article
Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions Academic Article
Insulin Activates a p21-activated Kinase in Muscle Cells via Phosphatidylinositol 3-Kinase Academic Article
Insulin Receptor Autophosphorylation and Signaling is Altered by Modulation of Membrane Physical Properties Academic Article
Insulin signaling and limb-patterning: candidate pathways for the origin and evolutionary diversification of beetle ‘horns’ Academic Article
Insulin signalling in mushroom body neurons regulates feeding behaviour inDrosophilalarvae Academic Article
Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1 Academic Article
Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response Academic Article
Integrins Regulate Responsiveness to Slit Repellent Signals Academic Article
Integrins are required for cardioblast polarisation in Drosophila Academic Article
Interaction of Peptide Substrates of Fibroblast Collagenase with Divalent Cations: Ca2+ Binding by Substrate as a Suggested Recognition Signal for Collagenase Action Academic Article
Interaction of c-Abl and p73α and their collaboration to induce apoptosis Academic Article
Interferon Gamma in Successful Pregnancies1 Academic Article
Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function Academic Article
Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase Academic Article
Interleukins 4 and 13 Increase Intestinal Epithelial Permeability by a Phosphatidylinositol 3-Kinase Pathway Academic Article
Interplay of the Peroxisome Proliferator-activated Receptor and the Thyroid Hormone Receptor-signaling Pathways in Regulating Peroxisome Proliferator?responsive Genes Academic Article
Intracellular Trafficking of CD23: Differential Regulation in Humans and Mice by Both Extracellular and Intracellular Exons Academic Article
Intracellular signalling by nucleotide receptors in PC12 pheochromocytoma cells Academic Article
Intrinsic pathway of apoptosis in peripheral blood eosinophils of Churg–Strauss syndrome Academic Article
Investigation of FGFR2-IIIC Signaling via FGF-2 Ligand for Advancing GCT Stromal Cell Differentiation Academic Article
Involvement of astrocytes in purine‐mediated reparative processes in the brain Academic Article
Involvement of multiple sulfhydryl groups in melatonin signal transduction in chick brain Academic Article
Involvement of the actin network in insulin signalling. Conference Paper
Ionic mechanisms and Ca2+ handling in airway smooth muscle Academic Article
Ionic mechanisms and Ca²⁺regulation in airway smooth muscle contraction: do the data contradict dogma? Academic Article
Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells Academic Article
Ionotropic Receptors in Pulmonary Neuroepithelial Bodies (NEB) and their Possible Role in Modulation of Hypoxia Signalling Academic Article
Is there convergence in the molecular pathways underlying the repeated evolution of sociality in African cichlids? Academic Article
Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca²⁺ handling and Rho/ROCK signaling Academic Article
Isoprostanes and Lung Vascular Pathology Academic Article
Isoprostanes constrict human radial artery by stimulation of thromboxane receptors, Ca2+ release, and RhoA activation Academic Article
It’s Not Easy Being Blue: Are There Olfactory and Visual Trade-Offs in Plant Signalling? Academic Article
Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells Academic Article
Jnk1 activity lowers the cellular production of H2O2 and modulates the growth arrest response to scavenging of H2O2 by catalase Academic Article
JunD/AP-1 Antagonizes the Induction of DAPK1 To Promote the Survival of v-Src-Transformed Cells Academic Article
Just-in-time transcription program in metabolic pathways Academic Article
Kaiso Represses the Cell Cycle Gene cyclin D1 via Sequence-Specific and Methyl-CpG-Dependent Mechanisms Academic Article
Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells Academic Article
Ketamine-induced neurotoxicity is mediated through endoplasmic reticulum stress in vitro in STHdhQ7/Q7 cells Academic Article
Kinase-specific responsiveness to incremental contractile activity in skeletal muscle with low and high mitochondrial content Academic Article
Largen: A Molecular Regulator of Mammalian Cell Size Control Academic Article
Leptin Therapy Reverses Hyperglycemia in Mice With Streptozotocin-Induced Diabetes, Independent of Hepatic Leptin Signaling Academic Article
Leucine supplementation is anti-atrophic during paradoxical sleep deprivation in rats Academic Article
Leukemia inhibitory factor increases glucose uptake in mouse skeletal muscle Academic Article
Leukotriene D4 receptors are not negatively coupled to adenylyl cyclase in guinea-pig lung parenchyma Academic Article
Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women Academic Article
Lipogenesis inhibitors: therapeutic opportunities and challenges Academic Article
Local Regulation of Thyroid Hormone Signaling Chapter
Long Double-Stranded RNA Induces an Antiviral Response Independent of IFN Regulatory Factor 3, IFN-β Promoter Stimulator 1, and IFN Academic Article
Looks Who’s Talking Now Academic Article
Loss of Hepatocyte-Nuclear-Factor-1α Impacts on Adult Mouse Intestinal Epithelial Cell Growth and Cell Lineages Differentiation Academic Article
Loss of dystrophin expression in skeletal muscle is associated with senescence of macrophages and endothelial cells. Academic Article
Loss-of-Function Mutations in MC4R Are Very Rare in the Greek Severely Obese Adult Population Academic Article
Low Density Lipoprotein Receptor-Related Protein-2 Expression in Efferent Duct and Epididymal Epithelia: Evidence in Rats for its in Vivo Role in Endocytosis of Apolipoprotein J/Clusterin1 Academic Article
Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men Academic Article
Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer Academic Article
Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis Academic Article
Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) Academic Article
Lysosomal and Proteasomal Degradation Play Distinct Roles in the Life Cycle of Cx43 in Gap Junctional Intercellular Communication-deficient and -competent Breast Tumor Cells Academic Article
MAPping the kinase landscape of macrophage activation Academic Article
MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial Trehalose Dimycolate and Mycobacterium tuberculosis Academic Article
MD-1 is a Critical Part of the Mechanism Causing Th1-Cytokine-Triggered Murine Fetal Loss Syndrome Academic Article
Macrophages Regulate Unilateral Ureteral Obstruction-Induced Renal Lymphangiogenesis through C-C Motif Chemokine Receptor 2–Dependent Phosphatidylinositol 3-Kinase-AKT–Mechanistic Target of Rapamycin Signaling and Hypoxia-Inducible Factor-1α/Vascular Endothelial Growth Factor-C Expression Academic Article
Mammary glands exhibit molecular laterality and undergo left–right asymmetric ductal epithelial growth in MMTV-cNeu mice* Academic Article
Maternal Nicotine Exposure Leads to Impaired Disulfide Bond Formation and Augmented Endoplasmic Reticulum Stress in the Rat Placenta Academic Article
Maternal nutrient restriction impairs young adult offspring ovarian signaling resulting in reproductive dysfunction and follicle loss† Academic Article
Mathematical model for chemotherapeutic drug efficacy in arresting tumour growth based on the cancer stem cell hypothesis Academic Article
Mathematical model for the cancer stem cell hypothesis Academic Article
Mathematical model of the role of intercellular signalling in intercellular cooperation during tumorigenesis Academic Article
Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis Academic Article
Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer. Academic Article
Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through β-catenin signaling Academic Article
Matters of taste: bridging molecular physiology and the humanities Academic Article
Mechanical Strain-Induced RhoA Activation Requires NADPH Oxidase-Mediated ROS Generation in Caveolae Academic Article
Mechanical Stretch-Induced Signal Transduction in Cultured Mesangial Cells Academic Article
Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis Conference Paper
Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK Academic Article
Mechanisms Employed by Herpes Simplex Virus 1 to Inhibit the Interferon Response Academic Article
Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma Academic Article
Mechanisms associated with mitochondrial-generated reactive oxygen species in cancerThis article is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease. Academic Article
Mechanisms of Cardiovascular Toxicity of BCR-ABL1 Tyrosine Kinase Inhibitors in Chronic Myelogenous Leukemia Academic Article
Mechanisms of exercise‐induced survival motor neuron expression in the skeletal muscle of spinal muscular atrophy‐like mice Academic Article
Mechanisms of innate immune activation by gluten peptide p31-43 in mice Academic Article
Medulloblastoma stem cells: Modeling tumor heterogeneity Academic Article
Medulloblastoma stem cells: where development and cancer cross pathways Academic Article
Melatonin and Hippo Pathway: Is There Existing Cross-Talk? Academic Article
Melatonin—A pleiotropic, orchestrating regulator molecule Academic Article
Membrane components can modulate the substrate specificity of protein kinase C Academic Article
Membrane shape as determinant of protein properties Academic Article
Mesangial cell signaling cascades in response to mechanical strain and glucose Academic Article
Metabolic Syndrome and Acute Hyperglycemia Are Associated With Endoplasmic Reticulum Stress in Human Mononuclear Cells Academic Article
Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment Academic Article
Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC Academic Article
Metformin: Metabolic Rewiring Faces Tumor Heterogeneity Academic Article
Methylation-dependent regulation of hypoxia inducible factor-1 alpha gene expression by the transcription factor Kaiso Academic Article
Mice with a Targeted Mutation of Patched2 Are Viable but Develop Alopecia and Epidermal Hyperplasia Academic Article
MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity Academic Article
MicroRNAs as Key Effectors in the p53 Network Academic Article
MicroRNAs: Non-coding fine tuners of receptor tyrosine kinase signalling in cancer Academic Article
Microvesicles Contribute to the Bystander Effect of DNA Damage Academic Article
Mind the gap: Signal movement through plasmodesmata is critical for the manifestation of SAR Academic Article
Mitochondrial Proteins at Unexpected Cellular Locations: Export of Proteins from Mitochondria from an Evolutionary Perspective Academic Article
Mitochondrial contributions to cancer cell physiology: potential for drug development Academic Article
Mitochondrial dysfunction is associated with a pro-apoptotic cellular environment in senescent cardiac muscle Academic Article
Modifying the Organ Matrix Pre-engraftment: A New Transplant Paradigm? Academic Article
Modular pharmacology-based approach to identify hub genes and kernel pathways of taodan granules treated psoriasis Academic Article
Modularity of protein function: Chimeric interleukin 1.beta.s containing specific protease inhibitor loops retain function of both molecules Academic Article
Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis Academic Article
Modulation of Hepatic Granulomatous Responses by Transgene Expression of DAP12 or TREM-1-Ig Molecules Academic Article
Modulation of Human Airway Smooth Muscle Migration by Lipid Mediators and Th-2 Cytokines Academic Article
Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication Academic Article
Modulation of autophagy signaling with resistance exercise and protein ingestion following short-term energy deficit Academic Article
Modulation of insulin action by vanadate: evidence of a role for phosphotyrosine phosphatase activity to alter cellular signaling Academic Article
Modulation of oxidative phosphorylation (OXPHOS) by radiation- induced biophotons Academic Article
Molecular Genetic Analysis of the Idd4 Locus Implicates the IFN Response in Type 1 Diabetes Susceptibility in Nonobese Diabetic Mice Academic Article
Molecular Mechanisms Linking Diabetes to the Accelerated Development of Atherosclerosis Academic Article
Molecular Pathways: Epigenetic Modulation of Wnt–Glycogen Synthase Kinase-3 Signaling to Target Human Cancer Stem Cells Academic Article
Molecular Pathways: Leveraging the BCL-2 Interactome to Kill Cancer Cells—Mitochondrial Outer Membrane Permeabilization and Beyond Academic Article
Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States Academic Article
Molecular and Histological Analysis of a New Rat Model of Experimental Knee Osteoarthritis Conference Paper
Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice Academic Article
Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis Academic Article
Molecules in focus Transforming growth factor-beta (TGF-β) Academic Article
Monocytic Differentiation of Acute Promyelocytic Leukemia Cells in Response to 1,25-Dihydroxyvitamin D3 Is Independent of Nuclear Receptor Binding Academic Article
Mood and gut feelings Academic Article
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15 Academic Article
Multifactorial Regulation of Prostaglandin Synthesis in Preovulatory Goldfish Ovarian Follicles1 Academic Article
Multiple Signaling Pathways Control the Activation of the CEF-4/9E3 Cytokine Gene by pp60v- Academic Article
Multiple histidines in the periplasmic domain of theSalmonella entericasensor kinase SsrA enhance signaling in response to extracellular acidification Academic Article
Multitargeted anti-angiogenic agents and NSCLC: Clinical update and future directions Academic Article
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells Academic Article
Muscarinic acetylcholine receptor activation increases transcellular transport of macromolecules across mouse and human intestinal epitheliumin vitro Academic Article
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition Academic Article
Mutations in TBCK, Encoding TBC1-Domain-Containing Kinase, Lead to a Recognizable Syndrome of Intellectual Disability and Hypotonia Academic Article
Mutations inCaenorhabditis briggsaeidentify new genes important for limiting the response to EGF signaling during vulval development Academic Article
Myelin-Associated Glycoprotein Is a Myelin Signal that Modulates the Caliber of Myelinated Axons Academic Article
Myostatin inhibition therapy for insulin-deficient type 1 diabetes Academic Article
Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts Academic Article
N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation Academic Article
NME4/nucleoside diphosphate kinase D in cardiolipin signaling and mitophagy Academic Article
NOD1 Activators Link Innate Immunity to Insulin Resistance Academic Article
NRAGE, A Novel MAGE Protein, Interacts with the p75 Neurotrophin Receptor and Facilitates Nerve Growth Factor–Dependent Apoptosis Academic Article
NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway Academic Article
Naphthenic Acid Mixtures from Oil Sands Process-Affected Water Enhance Differentiation of Mouse Embryonic Stem Cells and Affect Development of the Heart Academic Article
Nerve growth factor treatment alters Ca2+ pump levels in PC12 cells Academic Article
Neuroimmunologic and Neurotrophic Interactions in Autism Spectrum Disorders: Relationship to Neuroinflammation Academic Article
Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line Academic Article
Neutralization of LPS or blockage of TLR4 signaling prevents stress-triggered fetal loss in murine pregnancy Academic Article
Neutrons do not produce a bystander effect in zebrafish irradiated in vivo Academic Article
New therapeutic strategies to treat human cancers expressing mutant p53 proteins Academic Article
New treatment and markers of prognosis for idiopathic pulmonary fibrosis: lessons learned from translational research Academic Article
Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells Academic Article
Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells Academic Article
Nitric oxide, human diseases and the herbal products that affect the nitric oxide signalling pathway Academic Article
Nitric oxide-dependent changes in Schistosoma mansoni gene expression Academic Article
Non-Canonical Allostery in Cyclic Nucleotide Dependent Kinases Academic Article
Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin Academic Article
Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota Academic Article
Noncanonical Wnt Signaling Orchestrates Early Developmental Events toward Hematopoietic Cell Fate from Human Embryonic Stem Cells Academic Article
Nonendothelial Aortic Source of Nitric Oxide in Wistar-Kyoto Normotensive and Spontaneous Hypertensive Rats Academic Article
Nonhematopoietic cells represent a more rational target of in vivo hedgehog signaling affecting normal or acute myeloid leukemia progenitors Academic Article
Normal and defective pathways in biogenesis and maintenance of the insulin storage pool Academic Article
Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma Academic Article
Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells Academic Article
Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells Academic Article
Novel paradigms of innate immune sensing of viral infections Academic Article
Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells Academic Article
Nuclear import of the BTB/POZ transcriptional regulator Kaiso Academic Article
Nutrient Sensing and Response Drive Developmental Progression in Caenorhabditis elegans Academic Article
Nutrient provision increases signalling and protein synthesis in human skeletal muscle after repeated sprints Academic Article
O-GlcNAc-glycosylation of β-catenin regulates its nuclear localization and transcriptional activity Academic Article
ORIGINAL ARTICLE: LPS-Induced Murine Abortions Require C5 but not C3, and are Prevented by Upregulating Expression of the CD200 Tolerance Signaling Molecule Academic Article
Obstacles to effective Toll-like receptor agonist therapy for hematologic malignancies Academic Article
Oncogenes belonging to the CSF-1 transduction pathway direct p53 tumor suppressor effects to monocytic differentiation in 32D cells Academic Article
Oncolytic bovine herpesvirus type 1 infects and kills breast tumor cells and breast cancer-initiating cells irrespective of tumor subtype Academic Article
Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: Regulation of the type-II IL-4 receptor chains IL-4Rα and IL-13Rα1 Academic Article
Oncostatin M Regulates Eotaxin Expression in Fibroblasts and Eosinophilic Inflammation in C57BL/6 Mice Academic Article
Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells Academic Article
Oncostatin M induction of eotaxin-1 expression requires the convergence of PI3′K and ERK1/2 MAPK signal transduction pathways Academic Article
Oncostatin M-Induced IL-6 Expression in Murine Fibroblasts Requires the Activation of Protein Kinase Cδ Academic Article
Ontogeny of O2 and CO2//H+ chemosensitivity in adrenal chromaffin cells: role of innervation Academic Article
Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma Academic Article
Opposing effects of IL-1β/COX-2/PGE2 pathway loop on islets in type 2 diabetes mellitus Academic Article
Overexpression of the Endoplasmic Reticulum 60 Protein ER-60 Downregulates ApoB100 Secretion by Inducing Its Intracellular Degradation via a Nonproteasomal Pathway: Evidence for an ER-60-Mediated and pCMB-Sensitive Intracellular Degradative Pathway Academic Article
Oxidative stress and Nrf2 signaling in McArdle disease Academic Article
Oxygen sensing in airway chemoreceptors Academic Article
Oxytocin down-regulates mesenteric afferent sensitivity via the enteric OTR/nNOS/NO/K_ATPpathway in rat Academic Article
Oxytocin hyperpolarizes cultured duodenum myenteric intrinsic primary afferent neurons by opening BK _Ca channels through IP ₃ pathway Academic Article
P2Y₂ Receptor Up-Regulation Induced by Guanosine or UTP in Rat Brain Cultured Astrocytes Academic Article
PDZK1 in leukocytes protects against cellular apoptosis and necrotic core development in atherosclerotic plaques in high fat diet fed ldl receptor deficient mice Academic Article
PIKfyve: a new fish in the growing pool of AMPK substrates Academic Article
PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells Academic Article
PPAR ligands decrease human airway smooth muscle cell migration and extracellular matrix synthesis Academic Article
PRY-1/Axin signaling regulates lipid metabolism in Caenorhabditis elegans Academic Article
Packing on the Pounds in Response to Bacterial Growth Conditions Academic Article
Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans Academic Article
Pan-urologic cancer genomic subtypes that transcend tissue of origin Academic Article
Panax notoginseng saponin is superior to aspirin in inhibiting platelet adhesion to injured endothelial cells through COX pathway in vitro Academic Article
Panax quinquefolium saponin combined with dual antiplatelet drugs inhibits platelet adhesion to injured HUVECs via PI3K/AKT and COX pathways Academic Article
Parallel multi-time point cell stimulation and lysis on-chip for studying early signaling events in T cell activation Academic Article
Pathway Pathology Academic Article
Pea3 Transcription Factors and Wnt1-Induced Mouse Mammary Neoplasia Academic Article
Peptide hormones, neurotransmitters, and drugs as Ca²⁺ ionophores: implications for signal transduction Academic Article
Perinatal Administration of a Selective Serotonin Reuptake Inhibitor Induces Impairments in Reproductive Function and Follicular Dynamics in Female Rat Offspring Academic Article
Perioperative cardiovascular system failure in South Asians undergoing cardiopulmonary bypass is associated with prolonged inflammation and increased Toll-like receptor signaling in inflammatory monocytes Academic Article
Peripheral Blood Gene Expression Changes during Allergen Inhalation Challenge in Atopic Asthmatic Individuals Academic Article
Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis Academic Article
Perturbations to Homeostasis in Experimental Models Revealed Innate Pathways Driving Food Allergy Academic Article
Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer Academic Article
Phosphatidylinositol 3-Kinase (PI3K) Signaling via Glycogen Synthase Kinase-3 (Gsk-3) Regulates DNA Methylation of Imprinted Loci Academic Article
Phosphoinositide 3-kinase inhibitors in advanced breast cancer: A systematic review and meta-analysis Academic Article
Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional Activity Academic Article
Placental Trophoblast from Successful Human Pregnancies Expresses the Tolerance Signaling Molecule, CD200 (OX-2)* Academic Article
Plasticity of Skeletal Muscle Mitochondria in Response to Contractile Activity Academic Article
Pleiotropic actions of factor Xa inhibition in cardiovascular prevention: mechanistic insights and implications for anti-thrombotic treatment Academic Article
Pleiotropic roles of Notch signaling in normal, malignant, and developmental hematopoiesis in the human Academic Article
Polymorphism in the Innate Immune Receptor SIRPα Controls CD47 Binding and Autoimmunity in the Nonobese Diabetic Mouse Academic Article
Pramanicin Analog Induces Apoptosis in Human Colon Cancer Cells: Critical Roles for Bcl-2, Bim, and p38 MAPK Signaling Academic Article
Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis Academic Article
Prolonged moderate-intensity aerobic exercise does not alter apoptotic signaling and DNA fragmentation in human skeletal muscle Academic Article
Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation Academic Article
Protean effects of a natural peptide agonist of the G protein-coupled secretin receptor demonstrated by receptor mutagenesis. Academic Article
Protective activity of guanosine in an in vitro model of Parkinson's disease. Academic Article
Protein Ingestion Increases Myofibrillar Protein Synthesis after Concurrent Exercise Academic Article
Protein arginine methyltransferase expression, localization, and activity during disuse-induced skeletal muscle plasticity Academic Article
Protein kinase C α modulates liver X receptor α transactivation Academic Article
Protein kinase Cα negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor Academic Article
Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation Academic Article
Proteins and cholesterol-rich domains Academic Article
Proteolytic Cleavage of Chemerin Protein Is Necessary for Activation to the Active Form, Chem157S, Which Functions as a Signaling Molecule in Glioblastoma Academic Article
Proteomic changes in the gills of wild-type and transgenic radiosensitive medaka following exposure to direct irradiation and to X-ray induced bystander signals Academic Article
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways Academic Article
Psychosis pathways converge via D2High dopamine receptors Academic Article
Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells Academic Article
Purification and characterization of VanR and the cytosolic domain of VanS: A two-component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147 Academic Article
Purine and pyrimidine nucleotides activate distinct signalling pathways in PC12 cells Academic Article
Purinergic Pathways in the Spinal Microglia as a Putative Target for Treatment of Chronic Abdominal Pain Academic Article
Pyruvate Is Synthesized by Two Pathways in Pea Bacteroids with Different Efficiencies for Nitrogen Fixation Academic Article
Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells Academic Article
Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production Academic Article
Quorum sensing in Escherichia coli and Salmonella typhimurium Academic Article
R-spondin1 Is a High Affinity Ligand for LRP6 and Induces LRP6 Phosphorylation and β-Catenin Signaling Academic Article
RIPK2 Dictates Insulin Responses to Tyrosine Kinase Inhibitors in Obese Male Mice Academic Article
Radiation and the regulatory landscape of neo2-Darwinism Academic Article
Radiation-Induced Bystander and other Non-Targeted Effects: Novel Intervention Points in Cancer Therapy? Academic Article
Radiation-induced bystander effects — implications for cancer Academic Article
Radiosensitization of glioma cells by modulation of Met signalling with the hepatocyte growth factor neutralizing antibody, AMG102 Academic Article
Radiotherapy and the potential exploitation of bystander effects Academic Article
Rapamycin does not prevent increases in myofibrillar or mitochondrial protein synthesis following endurance exercise Academic Article
Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insulin Signaling Academic Article
Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise Academic Article
Reactive oxygen species from mitochondria impacts trophoblast fusion and the production of endocrine hormones by syncytiotrophoblasts Academic Article
Recent advances in understanding viral evasion of type I interferon Academic Article
Recent insights into neuromuscular junction biology in Duchenne muscular dystrophy: Impacts, challenges, and opportunities Academic Article
Receptor Subunit-specific Action of Oncostatin M in Hepatic Cells and Its Modulation by Leukemia Inhibitory Factor Academic Article
Receptor domains of two-component signal transduction systems Academic Article
Receptor-interacting protein 140 interacts with and inhibits transactivation by, peroxisome proliferator-activated receptor α and liver-X-receptor α Academic Article
Receptor-mediated protein kinase activation and the mechanism of transmembrane signaling in bacterial chemotaxis Academic Article
Receptors and signaling pathway underlying relaxations to isoprostanes in canine and porcine airway smooth muscle Academic Article
Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity Academic Article
Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression Academic Article
Reduced carbohydrate availability enhances exercise-induced p53 signaling in human skeletal muscle: implications for mitochondrial biogenesis Academic Article
Regulation of Acidification and Apoptosis by SHP-1 and Bcl-2 Academic Article
Regulation of Eosinophilia in Asthma—New Therapeutic Approaches for Asthma Treatment Academic Article
Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M Academic Article
Regulation of Mitochondrial Biogenesis in Muscle by Endurance Exercise Academic Article
Regulation of Myogenic Differentiation by Androgens: Cross Talk between Androgen Receptor/ β-Catenin and Follistatin/Transforming Growth Factor-β Signaling Pathways Academic Article
Regulation of Rho/ROCK signaling in airway smooth muscle by membrane potential and [Ca²⁺]_i Academic Article
Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways Academic Article
Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain Academic Article
Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3 Academic Article
Regulation of a muralytic enzyme-encoding gene by two non-coding RNAs Academic Article
Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli. Academic Article
Regulation of gene expression in oncogenically transformed cells Academic Article
Regulation of glucose transporter 4 traffic by energy deprivation from mitochondrial compromise Academic Article
Regulation of plasminogen activator inhibitor-1 secretion by growth factors in smooth muscle cells Academic Article
Regulation of plasminogen activator inhibitor-1 secretion by urokinase and tissue plasminogen activator in rat epithelioid-type smooth muscle cells Academic Article
Regulation of signal transducer, gp130 and the lif receptor in acute inflammation in vivo Academic Article
Regulation of slow wave frequency by IP₃-sensitive calcium release in the murine small intestine Academic Article
Regulation of the proline regulatory axis and autophagy modulates stemness in TP73/p73 deficient cancer stem-like cells Academic Article
Regulation of the water channel aquaporin-1: isolation and reconstitution of the regulatory complex Academic Article
Regulatory properties of neuronal cdc2-like kinase Academic Article
Relaxin alters cardiac myofilament function through a PKC-dependent pathway Academic Article
Release of Neutrophil Extracellular Traps by Neutrophils Stimulated With Antiphospholipid Antibodies: A Newly Identified Mechanism of Thrombosis in the Antiphospholipid Syndrome Academic Article
Repellent Signaling by Slit Requires the Leucine-Rich Repeats Academic Article
Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis Academic Article
Resistance exercise decreases eIF2Bε phosphorylation and potentiates the feeding-induced stimulation of p70^S6K1 and rpS6 in young men Academic Article
Resistance exercise enhances mTOR and MAPK signalling in human muscle over that seen at rest after bolus protein ingestion Academic Article
Resistance exercise load does not determine training-mediated hypertrophic gains in young men Academic Article
Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men Academic Article
Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men Academic Article
Resistance training minimizes catabolic effects induced by sleep deprivation in rats Academic Article
Response regulator output in bacterial chemotaxis Academic Article
Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis Academic Article
Revisiting Type 2-high and Type 2-low airway inflammation in asthma: current knowledge and therapeutic implications Academic Article
Role of DAP12 in Innate and Adaptive Immune Responses Academic Article
Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC) Academic Article
Role of Ets transcription factors in mammary gland development and oncogenesis. Academic Article
Role of Sarcoplasmic Reticulum in the Contractile Function of Vascular Smooth Muscle as Studied by 2,5-Di-(Tert-Butyl)-1,4-Benzohydroquinone Academic Article
Role of Serum Amyloid A as an Intermediate in the IL-1 and PMA-Stimulated Signaling Pathways Regulating Expression of Rabbit Fibroblast Collagenase Academic Article
Role of bisphenol A on calcium influx and its potential toxicity on the testis of Danio rerio Academic Article
Role of glycoprotein IIa (beta 1 subunit of very late activation antigens) in platelet functions Academic Article
Role of inflammation in the pathogenesis of atherosclerosis and therapeutic interventions Academic Article
Role of serotonergic neurons in the Drosophila larval response to light Academic Article
Role of the COX2-PGE₂ axis in S. pneumoniae-induced exacerbation of experimental fibrosis Academic Article
Role of the actin cytoskeleton in insulin action Academic Article
Role of α-Helical Coiled-coil Interactions in Receptor Dimerization, Signaling, and Adaptation during Bacterial Chemotaxis Academic Article
Roles for VEGF‐C/NRP–2 axis in regulating renal tubular epithelial cell survival and autophagy during serum deprivation Academic Article
Roles of specific lipid species in the cell and their molecular mechanism Academic Article
SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells Academic Article
SBDS-deficient cells undergo accelerated apoptosis through the Fas-pathway Academic Article
SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells Academic Article
SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction Academic Article
SREBP-1 activation by glucose mediates TGF-β upregulation in mesangial cells Academic Article
SREBP-1 is a novel mediator of TGFβ1 signaling in mesangial cells Academic Article
STAT-6 Is an Absolute Requirement for Murine Rejection of Hymenolepis diminuta Academic Article
Saikosaponin d downregulates microRNA-155 and upregulates FGF2 to improve depression-like behaviors in rats induced by unpredictable chronic mild stress by negatively regulating NF-κB Academic Article
Salicylate enhances the response of prostate cancer to radiotherapy Academic Article
Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine Academic Article
SapB and the chaplins: connections between morphogenetic proteins in Streptomyces coelicolor Academic Article
Selective involvement of the PI3K/PKB/bad pathway in retinal cell death Academic Article
Semaphorin 3F Antagonizes Neurotrophin-Induced Phosphatidylinositol 3-Kinase and Mitogen-Activated Protein Kinase Kinase Signaling: A Mechanism for Growth Cone Collapse Academic Article
Sensitization of G Protein-Coupled Benzodiazepine Receptors in the Striatum of 6-Hydroxydopamine-Lesioned Rats Academic Article
Separate roles of IL-6 and oncostatin M in mouse macrophage polarizationin vitroandin vivo Academic Article
Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts Academic Article
Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells Academic Article
Shear flow-induced motility ofDictyostelium discoideumcells on solid substrate Academic Article
Shifting of Immune Responsiveness to House Dust Mite by Influenza A Infection: Genomic Insights Academic Article
Signal Transduction Pathways Involved in Enterohemorrhagic Escherichia coli -Induced Alterations in T84 Epithelial Permeability Academic Article
Signal Transduction within G-protein Coupled Receptors via an Ion Tunnel: A Hypothesis Academic Article
Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects Academic Article
Signal pathways involved in microbe–nematode interactions provide new insights into the biocontrol of plant-parasitic nematodes Academic Article
Signal processing at mammalian carotid body chemoreceptors Academic Article
Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells Academic Article
Signal transduction in bacterial chemotaxis. Academic Article
Signal transduction in smooth muscle as studied by the subcellular membrane approach Academic Article
Signaling at Crossroads: The Dialogue between PDEs and PKA is Spoken in Multiple Languages Academic Article
Signaling at the Fetomaternal Interface Academic Article
Signaling through dynamic linkers as revealed by PKA Academic Article
Simple Fluorescent Sensors Engineered with Catalytic DNA ‘MgZ’ Based on a Non-Classic Allosteric Design Academic Article
Sirolimus and mTORC1: centre stage in the story of what makes muscles bigger? Academic Article
Skeletal Muscle Lipogenic Protein Expression Is Not Different between Lean and Obese Individuals: A Potential Factor in Ceramide Accumulation Academic Article
Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK Academic Article
Skeletal muscle myoblasts possess a stretch-responsive local angiotensin signalling system Academic Article
Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis Academic Article
Smad3 Signaling Involved in Pulmonary Fibrosis and Emphysema Academic Article
Smad3-dependent and -independent pathways are involved in peritoneal membrane injury Academic Article
Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling Academic Article
Socs1 Deficiency Enhances Hepatic Insulin Signaling Academic Article
Sox9-related signaling controls zebrafish juvenile ovary–testis transformation Academic Article
Specialized and shared functions of diguanylate cyclases and phosphodiesterases in Streptomyces development Academic Article
Specific CD45 isoforms differentially regulate T cell receptor signaling. Academic Article
Sphingosine-1-Phosphate Receptor 1, Expressed in Myeloid Cells, Slows Diet-Induced Atherosclerosis and Protects against Macrophage Apoptosis in Ldlr KO Mice Academic Article
Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase Academic Article
Stat6 dependent goblet cell hyperplasia during intestinal nematode infection Academic Article
Sterol Regulatory Element Binding Protein (SREBP)-1 is a novel regulator of the Transforming Growth Factor (TGF)-β receptor I (TβRI) through exosomal secretion Academic Article
Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Academic Article
Stimulatory and inhibitory signaling molecules that regulate renal branching morphogenesis Academic Article
Streptomyces exploration is triggered by fungal interactions and volatile signals Academic Article
Stress neuropeptides evoke epithelial responses via mast cell activation in the rat colon Academic Article
Stress-responsive signal transduction mechanisms in glomerular cells Academic Article
Stretch activation of Jun N-terminal kinase/stress-activated protein kinase in mesangial cells Academic Article
Stretch-induced Activation of Transforming Growth Factor-β₁ in Pulmonary Fibrosis Academic Article
Stretch-induced Raf-1 activation in mesangial cells requires actin cytoskeletal integrity Academic Article
Stromal β-catenin overexpression contributes to the pathogenesis of renal dysplasia Academic Article
Stromally Expressed β-Catenin Modulates Wnt9b Signaling in the Ureteric Epithelium Academic Article
Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases Academic Article
Structures and Solution Properties of Two Novel Periplasmic Sensor Domains with c-Type Heme from Chemotaxis Proteins of Geobacter sulfurreducens: Implications for Signal Transduction Academic Article
Subgroup-specific structural variation across 1,000 medulloblastoma genomes Academic Article
Substance P activates Cl⁻ and K⁺ conductances in guinea-pig tracheal smooth muscle cells Academic Article
Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability Academic Article
Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity Academic Article
Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo Academic Article
Swelling‐induced chloride current in glioblastoma proliferation, migration, and invasion Academic Article
Synapse Formation and Hypoxic Signalling in Co-Cultures of Rat Petrosal Neurones and Carotid Body Type 1 Cells Academic Article
Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis Academic Article
Synergy in Induction of Increased Renal Allograft Survival after Portal Vein Infusion of Dendritic Cells Transduced to Express TGFβ and IL-10, along with Administration of CHO Cells Expressing the Regulatory Molecule OX-2 Academic Article
Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits Academic Article
Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways Academic Article
Systemic acquired resistance networks amplify airborne defense cues Academic Article
T cell-mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells Academic Article
TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells Academic Article
TGF- receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung Academic Article
TGF-β and Smad3 Signaling Link Inflammation to Chronic Fibrogenesis Academic Article
TGFβ receptor I transactivation mediates stretch-induced Pak1 activation and CTGF upregulation in mesangial cells Academic Article
TLR2 Plays a Pivotal Role in Mediating Mucosal Serotonin Production in the Gut Academic Article
TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathway Academic Article
TNF-α is a critical negative regulator of type 1 immune activation during intracellular bacterial infection Academic Article
TRIM33 prevents pulmonary fibrosis by impairing TGF-β1 signalling Academic Article
Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR Academic Article
Targeting AMP-activated protein kinase (AMPK) for treatment of autosomal dominant polycystic kidney disease Academic Article
Targeting C3a/C5a receptors inhibits human mesangial cell proliferation and alleviates immunoglobulin A nephropathy in mice Academic Article
Targeting Genes for Treatment in Idiopathic Pulmonary Fibrosis: Challenges and Opportunities, Promises and Pitfalls Academic Article
Targeting Myelin to Optimize Plasticity of Spared Spinal Axons Academic Article
Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology Academic Article
Targeting apoptosis: preclinical and early clinical experience with mapatumumab, an agonist monoclonal antibody targeting TRAIL-R1 Academic Article
Telomerase Mediates Vascular Endothelial Growth Factor-dependent Responsiveness in a Rat Model of Hind Limb Ischemia Academic Article
Temtamy Preaxial Brachydactyly Syndrome Is Caused by Loss-of-Function Mutations in Chondroitin Synthase 1, a Potential Target of BMP Signaling Academic Article
Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors. Academic Article
Testosterone inhibits transforming growth factor-β signaling during myogenic differentiation and proliferation of mouse satellite cells: Potential role of follistatin in mediating testosterone action Academic Article
Thaxtomin A-deficient endophytic Streptomyces sp. enhances plant disease resistance to pathogenic Streptomyces scabies Academic Article
The Antibiotic Resistome: A Guide for the Discovery of Natural Products as Antimicrobial Agents Academic Article
The CD200 tolerance-signaling molecule and its receptor, CD200R1, are expressed in human placental villus trophoblast and in peri-implant decidua by 5 weeks’ gestation Academic Article
The Circadian Clock Gene, Bmal1, Regulates Intestinal Stem Cell Signaling and Represses Tumor Initiation Academic Article
The Cleaved Peptide of PAR1 Results in a Redistribution of the Platelet Surface GPIb-IX-V Complex to the Surface-Connected Canalicular System Academic Article
The Effects of Leptin on Airway Smooth Muscle Responses Academic Article
The GRHL2/ZEB Feedback Loop-A Key Axis in the Regulation of EMT in Breast Cancer Academic Article
The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma Academic Article
The Gastrin-Releasing Peptide Receptor as a Therapeutic Target in Central Nervous System Disorders Academic Article
The Herpes Simplex Virus 1-Encoded Envelope Glycoprotein B Activates NF-κB through the Toll-Like Receptor 2 and MyD88/TRAF6-Dependent Signaling Pathway Academic Article
The Hippo Tumor Suppressor Pathway: A Brainstorming WorkshopA report on the research meeting “The Hippo Tumor Suppressor Pathway: A Brainstorming Workshop” sponsored mainly by the Regina Elena Cancer Center and the Nicola Foundation and held in Rome, Italy, on 22 and 23 April 2009. Academic Article
The Hippo tumor suppressor pathway: a report on ‘the second workshop on the Hippo tumor suppressor pathway’ Academic Article
The Human Microbiota in Multiple Myeloma and Proteasome Inhibitors Academic Article
The Imprinted Gene Neuronatin Is Regulated by Metabolic Status and Associated With Obesity Academic Article
The Influence of Cigarette Smoking on Viral Infections Academic Article
The Involvement of Calcium and MAP Kinase Signaling Pathways in the Production of Radiation-Induced Bystander Effects Academic Article
The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule Academic Article
The Methyltransferase Smyd1 Mediates LPS-Triggered Up-Regulation of IL-6 in Endothelial Cells Academic Article
The NK Receptor NKp30 Mediates Direct Fungal Recognition and Killing and Is Diminished in NK Cells from HIV-Infected Patients Academic Article
The Nitric Oxide Pathway Provides Innate Antiviral Protection in Conjunction with the Type I Interferon Pathway in Fibroblasts Academic Article
The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm Academic Article
The Order of Exercise during Concurrent Training for Rehabilitation Does Not Alter Acute Genetic Expression, Mitochondrial Enzyme Activity or Improvements in Muscle Function Academic Article
The Orphan Nuclear Hormone Receptor LXRα Interacts with the Peroxisome Proliferator-activated Receptor and Inhibits Peroxisome Proliferator Signaling Academic Article
The P2Y6 Receptor Mediates Clostridium difficile Toxin-Induced CXCL8/IL-8 Production and Intestinal Epithelial Barrier Dysfunction Academic Article
The POZ-ZF Transcription Factor Kaiso (ZBTB33) Induces Inflammation and Progenitor Cell Differentiation in the Murine Intestine Academic Article
The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-β Oligomer Toxicity Academic Article
The Pulmonary Biology of Isoprostanes Academic Article
The RING‐finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling inDrosophila Academic Article
The Role of Dietary Fat throughout the Prostate Cancer Trajectory Academic Article
The Role of Endoplasmic Reticulum Stress-Glycogen Synthase Kinase-3 Signaling in Atherogenesis Academic Article
The Role of Serotonin in Breast Cancer Stem Cells Academic Article
The Role of the TL1A/DR3 Axis in the Activation of Group 2 Innate Lymphoid Cells in Subjects with Eosinophilic Asthma Academic Article
The Suppressor of Cytokine Signaling 3 Inhibits Leptin Activation of AMP-Kinase in Cultured Skeletal Muscle of Obese Humans Academic Article
The Trophic Effects of Purines and Purinergic Signaling in Pathologic Reactions of Astrocytes Academic Article
The YebC Family Protein PA0964 Negatively Regulates the Pseudomonas aeruginosa Quinolone Signal System and Pyocyanin Production Academic Article
The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades. Academic Article
The acute phase response of the liver in inflammation. Academic Article
The common inflammatory etiology of depression and cognitive impairment: a therapeutic target Academic Article
The complex roles of STAT3 and STAT5 in maintaining redox balance: Lessons from STAT-mediated xCT expression in cancer cells Academic Article
The control of testicular androgen production in the goldfish: Effects of activators of different intracellular signalling pathways Academic Article
The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo Academic Article
The dynamic microbe: green fluorescent protein brings bacteria to light Academic Article
The effect of montelukast, budesonide alone, and in combination on exercise-induced bronchoconstriction Academic Article
The effect of smoking cessation pharmacotherapies on pancreatic beta cell function Academic Article
The fate of released histamine: reception, response and termination. Conference Paper
The fight between the teleost fish immune response and aquatic viruses Academic Article
The function of IGF-IR in NNK-mediated lung tumorigenesis Academic Article
The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system Academic Article
The impact of body mass index in gene expression of reelin pathway mediators in individuals with schizophrenia and mood disorders: A post-mortem study Academic Article
The integrative role of leptin, oestrogen and the insulin family in obesity‐associated breast cancer: potential effects of exercise Academic Article
The interplay between the intestinal microbiota and the brain Academic Article
The lnterleukin-5/Receptor Interaction Activates Lyn and Jak2 Tyrosine Kinases and Propagates Signals via the Ras-Raf-1-MAP Kinase and the Jak-STAT Pathways in Eosinophils Conference Paper
The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms Academic Article
The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus Academic Article
The p53/p21 DNA damage-signaling pathway is defective in most meningioma cells Academic Article
The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway Academic Article
The plant signal salicylic acid shuts down expression of the vir regulon and activates quormone-quenching genes in Agrobacterium Academic Article
The rapid effects of estrogen: a mini-review Academic Article
The recognition of biomaterials: Pattern recognition of medical polymers and their adsorbed biomolecules Academic Article
The regulation of cardiac activity by nitric oxide (NO) in the Vietnamese stick insect, Baculum extradentatum Academic Article
The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise Academic Article
The role of ICP0-Null HSV-1 and interferon signaling defects in the effective treatment of breast adenocarcinoma Academic Article
The role of microRNAs in prethrombotic status associated with coronary artery disease Academic Article
The role of serotonin and its receptors in activation of immune responses and inflammation Academic Article
The role of sphingosine kinase 2 in alcoholic liver disease Academic Article
The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression Academic Article
The sex-limited effects of mutations in the EGFR and TGF-β signaling pathways on shape and size sexual dimorphism and allometry in the Drosophila wing Academic Article
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation Academic Article
The telomerase tale in vascular aging: regulation by estrogens and nitric oxide signaling Academic Article
The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors Academic Article
The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis Academic Article
The tissue polarity gene nemo carries out multiple roles in patterning during Drosophila development Academic Article
The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells Academic Article
The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout Academic Article
Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia Academic Article
Therapeutic approaches for muscle wasting disorders Academic Article
Thermosensing Coordinates a Cis-regulatory Module for Transcriptional Activation of the Intracellular Virulence System in Salmonella enterica Serovar Typhimurium Academic Article
Thrombospondin-1/CD47 signaling modulates transmembrane cation conductance, survival, and deformability of human red blood cells Academic Article
Thyroid hormone receptor α in breast cancer: prognostic and therapeutic implications Academic Article
Thyroid hormone regulation of thermal acclimation in ectotherms: Physiological mechanisms and ecoevolutionary implications Academic Article
Tie2 protects the vasculature against thrombus formation in systemic inflammation Academic Article
Tissue-Specific Role of Glycogen Synthase Kinase 3β in Glucose Homeostasis and Insulin Action Academic Article
Tolerance Signaling Molecules Academic Article
Tolerance Signaling Molecules and Pregnancy: IDO, Galectins, and the Renaissance of Regulatory T Cells Academic Article
Toll-like Receptor 9, CpG DNA and Innate Immunity Academic Article
Toll‐Like Receptor (TLR)–3, but Not TLR4, Agonist Protects against Genital Herpes Infection in the Absence of Inflammation Seen with CpG DNA Academic Article
Transactivation by PPAR/RXR heterodimers in yeast is potentiated by exogenous fatty acid via a pathway requiring intact peroxisomes. Academic Article
Transcriptome and translational signaling following endurance exercise in trained skeletal muscle: impact of dietary protein Academic Article
Transcriptomic and proteomic analyses in bone tumor cells: Deciphering parathyroid hormone-related protein regulation of the cell cycle and apoptosis Academic Article
Transfusion-related immunomodulation due to peripheral blood dendritic cells expressing the CD200 tolerance signaling molecule and alloantigen Academic Article
Transgenic plants with altered ethylene biosynthesis or perception Academic Article
Transplantation of human hematopoietic repopulating cells: mechanisms of regeneration and differentiation using human???mouse xenografts Academic Article
Treatment with apolipoprotein A1 protects mice against doxorubicin-induced cardiotoxicity in a scavenger receptor class B, type I-dependent manner Academic Article
Treatment-induced cell cycle kinetics dictate tumor response to chemotherapy Academic Article
Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone Academic Article
Tryptophan‐derived serotonin‐kynurenine balance in immune activation and intestinal inflammation Academic Article
Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling Academic Article
Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity Academic Article
Type I IFN signaling on dendritic cells is required for NK cell-mediated anti-tumor immunity Academic Article
Type I interferon signalling is not required for the induction of endotoxin tolerance Academic Article
Type IV Pilin Proteins: Versatile Molecular Modules Academic Article
Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages Academic Article
Tyrosine phosphorylation and cadherin/catenin function Academic Article
UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways Academic Article
Uncoupling of Pro- and Anti-Inflammatory Properties of Staphylococcus aureus Academic Article
Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo Academic Article
Understanding the Role of DISC1 in Psychiatric Disease and during Normal Development Academic Article
Up-Regulation of the Complement System in Subcutaneous Adipocytes from Nonobese, Hypertriglyceridemic Subjects Is Associated with Adipocyte Insulin Resistance Academic Article
Update on bipolar disorder biomarker candidates Academic Article
Upregulating Nrf2-dependent antioxidant defenses in Pacific oysters Crassostrea gigas: Investigating the Nrf2/Keap1 pathway in bivalves Academic Article
Upregulation of IL-17A/F from human lung tissue explants with cigarette smoke exposure: implications for COPD Academic Article
Upregulation of MMP-13 via Runx2 in the stromal cell of Giant Cell Tumor of Bone Academic Article
Using G-deleted vesicular stomatitis virus to probe the innate anti-viral response Academic Article
VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents Academic Article
Vascular Endothelial Tissue Factor Pathway Inhibitor Kinetics in Culture Following Exposure to DX-9065a—A Selective and Direct Factor Xa Inhibitor Academic Article
Vascular Regenerative Cell Exhaustion in Diabetes: Translational Opportunities to Mitigate Cardiometabolic Risk Academic Article
Vascular Research at INABIS 98 Academic Article
Vascular β-adrenoceptor function in hypertension and in ageing Academic Article
Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles Academic Article
Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle Academic Article
Vasopressin increases intracellular NO concentration via Ca(2+) signaling in inner medullary collecting duct. Academic Article
Voices from within: gut microbes and the CNS Academic Article
W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity Academic Article
What have we learned from basic science studies on idiopathic pulmonary fibrosis? Academic Article
Whole-cell and perforated-patch recordings from O2-sensitive rat carotid body cells grown in short- and long-term culture Academic Article
Wnt3a Activates Dormant c-Kit− Bone Marrow-Derived Cells with Short-Term Multilineage Hematopoietic Reconstitution Capacity Academic Article
Wnt7a treatment ameliorates muscular dystrophy Academic Article
cAMP activation of PKA defines an ancient signaling mechanism Academic Article
miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis Academic Article
miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells Academic Article
nMET, A New Target in Recurrent Cancer Academic Article
p53: The pivot between cell cycle arrest and senescence Academic Article
p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade Academic Article
α-Adrenoceptor subtypes of dog saphenous vein: Another unusual property Academic Article
β-Catenin Causes Renal Dysplasia via Upregulation of Tgfβ2 and Dkk1 Academic Article
β-Catenin Overexpression in the Metanephric Mesenchyme Leads to Renal Dysplasia Genesis via Cell-Autonomous and Non–Cell-Autonomous Mechanisms Academic Article
β-Catenin/CBP–Dependent Signaling Regulates TGF-β–Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells Academic Article
β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens Academic Article
β-Subunit of the voltage-gated Ca ²⁺ channel Cav1.2 drives signaling to the nucleus via H-Ras Academic Article
β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer Academic Article
β2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis Academic Article
β‐adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling Academic Article
γ-aminobutyric acid nurtures allergic asthma Academic Article

Signal Transduction Concept

Vocabulary Service

Overview

subject area of