Journal article
Stat6 dependent goblet cell hyperplasia during intestinal nematode infection
Abstract
To identify the role of signal transducer and activator of transcription factor 6 (Stat6) in the development of intestinal goblet cell hyperplasia during nematode infection, we compared the number of goblet cells in Stat6 deficient (Stat6 -/-) mice with that generated in wild-type (Stat6 +/+) mice in Trichinella spiralis infection. The number of goblet cells significantly increased with infection in wild-type mice. However, Stat6 -/- failed to …
Authors
Khan WI; Blennerhasset P; Ma C; Matthaei KI; Collins SM
Journal
Parasite Immunology, Vol. 23, No. 1, pp. 39–42
Publisher
Wiley
Publication Date
January 26, 2001
DOI
10.1046/j.1365-3024.2001.00353.x
ISSN
0141-9838