Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β Academic Article uri icon

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abstract

  • Adhesion with macrophages promotes the activation of fibroblasts into myofibroblasts and creates a self-sustaining profibrotic niche.

authors

  • Lodyga, Monika
  • Cambridge, Elizabeth
  • Karvonen, Henna M
  • Pakshir, Pardis
  • Wu, Brian
  • Boo, Stellar
  • Kiebalo, Melanie
  • Kaarteenaho, Riitta
  • Glogauer, Michael
  • Kapoor, Mohit
  • Ask, Kjetil
  • Hinz, Boris

publication date

  • January 15, 2019