Journal article
Arachidonic Acid Metabolism and Kidney Inflammation
Abstract
As a major component of cell membrane lipids, Arachidonic acid (AA), being a major component of the cell membrane lipid content, is mainly metabolized by three kinds of enzymes: cyclooxygenase (COX), lipoxygenase (LOX), and cytochrome P450 (CYP450) enzymes. Based on these three metabolic pathways, AA could be converted into various metabolites that trigger different inflammatory responses. In the kidney, prostaglandins (PG), thromboxane (Tx), …
Authors
Wang T; Fu X; Chen Q; Patra JK; Wang D; Wang Z; Gai Z
Journal
International Journal of Molecular Sciences, Vol. 20, No. 15,
Publisher
MDPI
DOI
10.3390/ijms20153683
ISSN
1661-6596