Journal article
Distinguishing Between Mouse and Human Pluripotent Stem Cell Regulation: The Best Laid Plans of Mice and Men
Abstract
Pluripotent stem cells (PSCs) have been derived from the embryos of mice and humans, representing the two major sources of PSCs. These cells are universally defined by their developmental properties, specifically their self-renewal capacity and differentiation potential which are regulated in mice and humans by complex transcriptional networks orchestrated by conserved transcription factors. However, significant differences exist in the …
Authors
Schnerch A; Cerdan C; Bhatia M
Journal
Stem Cells, Vol. 28, No. 3, pp. 419–430
Publisher
Oxford University Press (OUP)
Publication Date
March 1, 2010
DOI
10.1002/stem.298
ISSN
1066-5099