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PRY-1/Axin signaling regulates lipid metabolism in...
Journal article

PRY-1/Axin signaling regulates lipid metabolism in Caenorhabditis elegans

Abstract

The nematode Caenorhabditis elegans constitutes a leading animal model to study how signaling pathway components function in conserved biological processes. Here, we describe the role of an Axin family member, PRY-1, in lipid metabolism. Axins are scaffolding proteins that play crucial roles in signal transduction pathways by physically interacting with multiple factors and coordinating the assembly of protein complexes. Genome-wide …

Authors

Ranawade A; Mallick A; Gupta BP

Journal

PLOS ONE, Vol. 13, No. 11,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0206540

ISSN

1932-6203