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Dual Pathway for Promotion of Stem Cell Neural...
Journal article

Dual Pathway for Promotion of Stem Cell Neural Differentiation Mediated by Gold Nanocomposites

Abstract

The neural differentiation of embryonic stem cells (ESCs) is of great value in the treatment of neurodegenerative diseases. On the basis of the two related signaling pathways that direct the neural differentiation of ESCs, we used gold nanoparticles (GNP) as a means of combining chemical and physical cues to trigger the neurogenic differentiation of stem cells. Neural differentiation-related functional units (glyco and sulfonate units on …

Authors

Zhang S; Hang Y; Wu J; Tang Z; Li X; Zhang S; Wang L; Brash JL; Chen H

Journal

ACS Applied Materials & Interfaces, Vol. 12, No. 19, pp. 22066–22073

Publisher

American Chemical Society (ACS)

Publication Date

May 13, 2020

DOI

10.1021/acsami.9b22258

ISSN

1944-8244