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Mechanisms Employed by Herpes Simplex Virus 1 to...
Journal article

Mechanisms Employed by Herpes Simplex Virus 1 to Inhibit the Interferon Response

Abstract

The interferon (IFN) family of cytokines constitutes potent inducers of innate antiviral responses that also influence adaptive immune processes. Despite eliciting such formidable cellular defense responses, viruses have evolved ways to interfere with the IFN response. Herpes simplex virus 1 (HSV-1) is an enveloped, dsDNA virus and a member of the herpesvirus family. Like other herpesvirus family members, HSV-1 has become highly specialized for …

Authors

Paladino P; Mossman KL

Journal

Journal of Interferon & Cytokine Research, Vol. 29, No. 9, pp. 599–608

Publisher

Mary Ann Liebert

Publication Date

September 2009

DOI

10.1089/jir.2009.0074

ISSN

1079-9907