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cTAZ: a safeguard factor of antiviral response
Journal article

cTAZ: a safeguard factor of antiviral response

Abstract

The antiviral response is a tightly regulated process that follows specific patterns of timing and duration. The type I interferon‐induced antiviral pathway is driven by JAK‐STAT signalling. This is characterized by the dimerization of the receptor upon ligand binding, inducing cytoplasmic protein–protein interactions between phosphorylated STAT1 and STAT2, dimerization and nuclear translocation, which leads to the formation of a trimeric …

Authors

Strano S; Blandino G

Journal

EMBO Reports, Vol. 20, No. 6,

Publisher

Springer Nature

Publication Date

June 2019

DOI

10.15252/embr.201948169

ISSN

1469-221X