Journal article
OX40L blockade and allergen‐induced airway responses in subjects with mild asthma
Abstract
BACKGROUND: The OX40/OX40L interaction contributes to an optimal T cell response following allergic stimuli and plays an important role in the maintenance and reactivation of memory T effector cells.
OBJECTIVE: We tested whether treatment with an anti-OX40L monoclonal antibody (MAb) would inhibit allergen-induced responses in subjects with asthma.
Authors
Gauvreau GM; Boulet L; Cockcroft DW; FitzGerald JM; Mayers I; Carlsten C; Laviolette M; Killian KJ; Davis BE; Larché M
Journal
Clinical & Experimental Allergy, Vol. 44, No. 1, pp. 29–37
Publisher
Wiley
Publication Date
January 2014
DOI
10.1111/cea.12235
ISSN
0954-7894