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Regulation of slow wave frequency by IP3-sensitive...
Journal article

Regulation of slow wave frequency by IP3-sensitive calcium release in the murine small intestine

Abstract

Slow waves determine frequency and propagation characteristics of contractions in the small intestine, yet little is known about mechanisms of slow wave regulation. We propose a role for intracellular Ca(2+), inositol 1,4,5,-trisphosphate (IP(3))-sensitive Ca(2+) release, and sarcoplasmic reticulum (SR) Ca(2+) content in the regulation of slow wave frequency because 1) 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid-AM, a cytosolic …

Authors

Malysz J; Donnelly G; Huizinga JD

Journal

AJP Gastrointestinal and Liver Physiology, Vol. 280, No. 3, pp. g439–g448

Publisher

American Physiological Society

Publication Date

March 1, 2001

DOI

10.1152/ajpgi.2001.280.3.g439

ISSN

0193-1857