Journal article
Proximal Gut Mucosal Epithelial Homeostasis in Aged IL-1 Type I Receptor Knockout Mice after Starvation
Abstract
BACKGROUND: Previous studies have shown that starvation induces small bowel atrophy, and that atrophy diminishes with aging. In this experiment, we assessed whether starvation-induced atrophy of proximal gut mucosa is associated with the Interleukin-1 receptor (IL-1R) signaling pathway in aged mice.
MATERIALS AND METHODS: Thirty 26-month-old IL-1R knockout mice and age-matched wild-type C57BL/6 mice were randomly divided into two groups: ad …
Authors
Song J; Wolf SE; Wu X-W; Finnerty CC; Herndon DN; Jeschke MG
Journal
Journal of Surgical Research, Vol. 169, No. 2, pp. 209–213
Publisher
Elsevier
Publication Date
August 2011
DOI
10.1016/j.jss.2010.03.056
ISSN
0022-4804