Calcium Regulation and Contractile Dysfunction of Smooth Muscle

A brief overview of recent findings of abnormal contractile function of smooth muscle under several selected pathophysiological conditions is presented and related to the dysfunction of the control of cytosolic calcium ion concentration, [Ca2+]. In diabetes mellitus (DM), contractile abnormalities depend on the animal species, vascular segments, mode of the induction of DM, and the period after the induction of DM. The abnormal contractile …