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Regulation of Eosinophilia in Asthma—New...
Journal article

Regulation of Eosinophilia in Asthma—New Therapeutic Approaches for Asthma Treatment

Abstract

Asthma is a complex and chronic inflammatory disease of the airways, characterized by variable and recurring symptoms, reversible airflow obstruction, bronchospasm, and airway eosinophilia. As the pathophysiology of asthma is becoming clearer, the identification of new valuable drug targets is emerging. IL-5 is one of these such targets because it is the major cytokine supporting eosinophilia and is responsible for terminal differentiation of …

Authors

Cusack RP; Whetstone CE; Xie Y; Ranjbar M; Gauvreau GM

Journal

Cells, Vol. 10, No. 4,

Publisher

MDPI

DOI

10.3390/cells10040817

ISSN

2073-4409